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MSVTSVLRRFNRTYTQRIGVLDESYLGTGRPLNVSRVLFEIGGLGAVTIRDLRDRLGLDSGYVTRILTRL ENEGLVRVVPDPADGRRRIVELTDAGREAVNELEDRSESRAADLVAPLTARQRERLADALATAELLVRAA TVRLVEVDQDSDVARTALTHYYDELNRRFPQGFDPGAPSGPEHGAHYIAAISDGQPVGFGGIRPLESGDD GPVAEVKRMWVDDRWRGAGLGSRILRHLETLAAEHGFARVRLDTNGNLGEAIALYERTGYAQIDRYNDNP YAQFFFEKRL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0469 | - | - | 100% (290) | transcriptional regulatory protein PadR- |
| M. smegmatis MC2 155 | MSMEG_0773 | - | 3e-10 | 30.50% (141) | acetyltransferase |
| M. smegmatis MC2 155 | MSMEG_1492 | - | 2e-07 | 40.51% (79) | transcriptional regulator, MarR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0758 | - | 2e-08 | 39.24% (79) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_5017 | - | 2e-08 | 35.14% (111) | MarR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0737 | - | 2e-08 | 39.24% (79) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1138c | - | 5e-61 | 45.36% (291) | MarR family transcriptional regulator |
| M. marinum M | MMAR_0228 | - | 6e-09 | 35.71% (98) | hypothetical protein MMAR_0228 |
| M. avium 104 | MAV_4763 | - | 2e-08 | 31.48% (162) | acetyltransferase, gnat family protein |
| M. thermoresistible (build 8) | TH_2302 | - | 1e-09 | 36.63% (101) | acetyltransferase |
| M. ulcerans Agy99 | MUL_4886 | - | 2e-08 | 34.69% (98) | hypothetical protein MUL_4886 |
| M. vanbaalenii PYR-1 | Mvan_0695 | - | 3e-11 | 31.91% (141) | GCN5-related N-acetyltransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0469|M.smegmatis_MC2_155 MS--VTSVLRRFNRTYTQRIGVLDESYLGTGRPLNVSRVLFEIGGLGAVT
MAB_1138c|M.abscessus_ATCC_199 MTDALVDGLRSFNRTVTQRIGVLESEYLARDRPLGQSRVLWEIGDSG-CD
TH_2302|M.thermoresistible__bu --------------------------------------------------
Mvan_0695|M.vanbaalenii_PYR-1 --------------------------------------------------
MAV_4763|M.avium_104 --------------------------------------------------
MMAR_0228|M.marinum_M --------------------------------------------------
MUL_4886|M.ulcerans_Agy99 --------------------------------------------------
Mb0758|M.bovis_AF2122/97 --------------------------------------------------
Rv0737|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5017|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_0469|M.smegmatis_MC2_155 IRDLRDRLGLDSGYVTRILTRLENEGLVRVVPDPADGRRRIVELTDAGRE
MAB_1138c|M.abscessus_ATCC_199 IRELRARLGLDSGYLSRLLRALEGAGLIEVTAADGDTRVRTARLTAAGRA
TH_2302|M.thermoresistible__bu ---------------------VSTVEQLSFQAVGRH--------------
Mvan_0695|M.vanbaalenii_PYR-1 MTTPRGKLRRARPTLDSVVMSVQTVGELRFVAVGQD--------------
MAV_4763|M.avium_104 ---------------MTPESSPPADGRLRFVPATHD--------------
MMAR_0228|M.marinum_M --------------------------MRRVLDAAWE--------------
MUL_4886|M.ulcerans_Agy99 --------------------------MRRVLDAAWE--------------
Mb0758|M.bovis_AF2122/97 -------------------MASDNRDPIAAARANWE--------------
Rv0737|M.tuberculosis_H37Rv -------------------MASDNRDPIAAARANWE--------------
Mflv_5017|M.gilvum_PYR-GCK ----MVIHTAGAPVRYERCVASDRPDPIATARDNWE--------------
.
MSMEG_0469|M.smegmatis_MC2_155 AVNELEDRSESRAADLVAPLTARQRERLADALATA-ELLVRAATVRLVEV
MAB_1138c|M.abscessus_ATCC_199 ELAELDRRSDDLAHSILEPLSVNQRQRLADAMAEV-ERLFVASQVQIAVM
TH_2302|M.thermoresistible__bu ---------HRLAEPLLAELAVEYAHRYDSTVDRV-ARWLRSAPAAEFEP
Mvan_0695|M.vanbaalenii_PYR-1 ---------DPLAAPLIDELAVEYADRYGGSRDKV-HAWLRGYPAAEFEA
MAV_4763|M.avium_104 ---------DPLARPLLAELAVEYAQRYGGTPSAH-LSWLP-VPRDELAP
MMAR_0228|M.marinum_M ----------PTVPALMQLVAATAAPRLRSAFAEAGLDGIRPAQAIGLVP
MUL_4886|M.ulcerans_Agy99 ----------PTVPALMQLVAATAAPRLRSAFAAAGLDGIRPAQAIGLVP
Mb0758|M.bovis_AF2122/97 --------RSGWGDVSLGMVAVTSVMRAHQILLARVETALRPYDLS----
Rv0737|M.tuberculosis_H37Rv --------RSGWGDVSLGMVAVTSVMRAHQILLARVETALRPYDLS----
Mflv_5017|M.gilvum_PYR-GCK --------RSGWHDVADGMVAVTSVMRAHQILLARVETALRPYDLS----
::. * .
MSMEG_0469|M.smegmatis_MC2_155 DQDSDVARTALTHYYDELNRRFPQGFDPG--APSGP----EHGAHYIAAI
MAB_1138c|M.abscessus_ATCC_199 DTRTPEARYCIRAYFEEISARFEDGFDPALTLPAGDAELCAPAGLFLVAA
TH_2302|M.thermoresistible__bu -----------------------------------------PDGALVIGL
Mvan_0695|M.vanbaalenii_PYR-1 -----------------------------------------PGGGLLIGL
MAV_4763|M.avium_104 -----------------------------------------PDGGLLIGV
MMAR_0228|M.marinum_M ----------------------------------------LAGGGLHASD
MUL_4886|M.ulcerans_Agy99 ----------------------------------------LAGGGLHASD
Mb0758|M.bovis_AF2122/97 ----------------------------------------FSRFELLRLL
Rv0737|M.tuberculosis_H37Rv ----------------------------------------FSRFELLRLL
Mflv_5017|M.gilvum_PYR-GCK ----------------------------------------FSRYELLRLL
MSMEG_0469|M.smegmatis_MC2_155 SDGQPVGFGGIRPLESGDDGPVAEVKRMWVDDRWRGAGLGSRILRHLETL
MAB_1138c|M.abscessus_ATCC_199 LHEEPVGCAGLKLPPHTD---TAEIKRVWIAPHVRGLGLGKRILAELERL
TH_2302|M.thermoresistible__bu LSGQPVTGGAFRRFDAHT----AELKRIWTDSRHRRRGHARALLAELERR
Mvan_0695|M.vanbaalenii_PYR-1 LDGQPVTGGAFRRFDDTT----AELKRIWTDARYRRRGLGQALVSRLEAD
MAV_4763|M.avium_104 VDGVPVTGGAFRRYDAET----AELKRIWTDAAHRRRGYARALLAALEER
MMAR_0228|M.marinum_M LADR---LGVSRQAVAQA---VTALERHGYVLRAPDPADARARIIELTP-
MUL_4886|M.ulcerans_Agy99 LADR---LGVSRQAVAQA---VAALERHGYVLRAPDPADARARIIELTP-
Mb0758|M.bovis_AF2122/97 AFSR---IGALPITKASDR---LQVHVTSVTHAIRRLEADGLVRRVPHPT
Rv0737|M.tuberculosis_H37Rv AFSR---IGALPITKASDR---LQVHVTSVTHAIRRLEADGLVRRVPHPT
Mflv_5017|M.gilvum_PYR-GCK AFSR---TGALPITKASDR---LQVHVTSVTHAIRRLEADGLVERLPHPT
. :.
MSMEG_0469|M.smegmatis_MC2_155 AAEHGFARVRLDTNGNLGEAIALYERTGYAQID---RYNDNPYAQFFFEK
MAB_1138c|M.abscessus_ATCC_199 AVDHGAHTIRLDTNRALTEAIAMYRSAGYDEVA---AFNQEKYAHFWFQK
TH_2302|M.thermoresistible__bu ITARGYRRIYLTTGDRQPEAEALYRAAGYSRLP-KPLPGDEEGYPVAFLK
Mvan_0695|M.vanbaalenii_PYR-1 IAARGYSRIYLTTGDRQPEAEALYSSLGYQRLE-EPLPAEGEVYAIAFLK
MAV_4763|M.avium_104 TRACGYRRLYLITGNRQPEAEALYDATGYTRVPPDPLPDWGPFRPIAFEK
MMAR_0228|M.marinum_M ---RGRQALRVMRANALDAQRRWQKILGPQRLG-----ELRETLQLLLDA
MUL_4886|M.ulcerans_Agy99 ---RGRQALRVMRANALDAQRRWQKILGPQRLG-----ELRETLQLLLDA
Mb0758|M.bovis_AF2122/97 DGRTTLVQITELGRSTVEDATVTLNEQVFANVGMGAEESQALVSAVETLR
Rv0737|M.tuberculosis_H37Rv DGRTTLVQITELGRSTVEDATVTLNEQVFANVGMGAEESQALVSAVETLR
Mflv_5017|M.gilvum_PYR-GCK DGRTTLVRITDLGRSTVEDATVTLNKDVFGDIGISGEQSRALADAIETLR
: : .
MSMEG_0469|M.smegmatis_MC2_155 RL-----
MAB_1138c|M.abscessus_ATCC_199 QLS----
TH_2302|M.thermoresistible__bu ELGGPGS
Mvan_0695|M.vanbaalenii_PYR-1 ELH----
MAV_4763|M.avium_104 WLVPNER
MMAR_0228|M.marinum_M ESGA---
MUL_4886|M.ulcerans_Agy99 ESGA---
Mb0758|M.bovis_AF2122/97 RNAGDF-
Rv0737|M.tuberculosis_H37Rv RNAGDF-
Mflv_5017|M.gilvum_PYR-GCK RSAGDF-