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VPLHTGPNGYDLDSFDDPDFLSAEVRYDLPRLGRLDGLDIAHLQCHIGTDTVWLSRLGPRSTVGLDFSPA ALQAARDLAMRARADVGFVEADVYDAVQALGGERFDLVYTGLGALCWIPSISRWADVFASLLRPGGRLFM REGHPFLWSLSDPRPDGLVVVEYPYFETSGIPFVEHETYAGNGTVASPQIIHFNHGLGEIFTALTAAGLM VTGLEEHREVPWNPLGDAMIPSPDYDGEFILAEDRDRIPMTYTVQAIKR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4458 | - | - | 100% (259) | hypothetical protein MUL_4458 |
| M. ulcerans Agy99 | MUL_2009 | - | 9e-05 | 26.72% (131) | methyltransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1550 | - | 7e-05 | 26.72% (131) | methyltransferase |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv1523 | - | 7e-05 | 26.72% (131) | methyltransferase |
| M. leprae Br4923 | MLBr_00130 | - | 9e-05 | 25.71% (140) | hypothetical protein MLBr_00130 |
| M. abscessus ATCC 19977 | MAB_1977 | - | 9e-06 | 27.96% (186) | putative methyltransferase |
| M. marinum M | MMAR_4607 | - | 1e-151 | 99.23% (259) | hypothetical protein MMAR_4607 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_0546 | - | 1e-100 | 66.28% (258) | hypothetical protein MSMEG_0546 |
| M. thermoresistible (build 8) | TH_1636 | - | 9e-08 | 30.56% (144) | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| M. vanbaalenii PYR-1 | Mvan_5314 | - | 7e-06 | 35.42% (96) | methyltransferase type 11 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4458|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4607|M.marinum_M --------------------------------------------------
MSMEG_0546|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00130|M.leprae_Br4923 ---------------------MAFTRIHSFLASAGNTSMYKR--------
TH_1636|M.thermoresistible__bu ---------------------VRESRDQVFRKLNEKLTQHG---------
Mb1550|M.bovis_AF2122/97 MTITALTVTLPLLWRRLTTAGVKYADQGHFVGSAGVPAADAGGRDAASEQ
Rv1523|M.tuberculosis_H37Rv MTITALTVTLPLLWRRLTTAGVKYADQGHFVGSAGVPAADAGGRDAASEQ
MAB_1977|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_5314|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4458|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4607|M.marinum_M --------------------------------------------------
MSMEG_0546|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_00130|M.leprae_Br4923 --------------------------------------------------
TH_1636|M.thermoresistible__bu --------------------------------------------------
Mb1550|M.bovis_AF2122/97 IARWTQTCTVVLVCGHGPAKWAFRSWCTSRSCDTLPVALRYRLQSNPLVG
Rv1523|M.tuberculosis_H37Rv IARWTQTCTVVLVCGHGPAKWAFRSWCTSRSCDTLPVALRYRLQSNPLVG
MAB_1977|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_5314|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_4458|M.ulcerans_Agy99 -------------------------MPLHTGPNGYDLDSFDDPDFLSAEV
MMAR_4607|M.marinum_M -MDDVSQRPMAASWRSLNLANWESRVPLHTGPNGYDLDSFDDPDFLSAEV
MSMEG_0546|M.smegmatis_MC2_155 ---------MVEDWRTLNLANWEARVPLHVSPGGYDLDSFSDPRHLSGVV
MLBr_00130|M.leprae_Br4923 --VWRFWYPLMTHKLGTDEIMFINWAYEEDPPMALPLEASDEPNRAHINL
TH_1636|M.thermoresistible__bu ---QKFIYSYASRRLDDDDVVFLNYGYEEDPPMGLPLSETDEPNRYSIQL
Mb1550|M.bovis_AF2122/97 KLTTKYFLPLGTRQVG-DHVVFFNFGYEEDPPMALPLSESDEPNRYCIQL
Rv1523|M.tuberculosis_H37Rv KLTTKYFLPLGTRQVG-DHVVFFNFGYEEDPPMALPLSESDEPNRYCIQL
MAB_1977|M.abscessus_ATCC_1997 -------------MDPAEHARHTRDVYDRLAPVWSATTDDGPFNGLLERP
Mvan_5314|M.vanbaalenii_PYR-1 ------MFARCRTAAHAGAMTHSPDAAALAEEWDERYTSLADRIPDGTPS
MUL_4458|M.ulcerans_Agy99 RYDLPRLGRLDGLDIAHLQCHIGTDTVWLSR-LGPRSTVGLDFSPAALQA
MMAR_4607|M.marinum_M RYDLPRLGRLDGLDIAHLQCHIGTDTVSLSR-LGPRSTVGLDFSPAALQA
MSMEG_0546|M.smegmatis_MC2_155 RYDLPRLGDITGLDVVHLQCHIGTDTVSLAR-LGPRSVTGLDFSPSAIAA
MLBr_00130|M.leprae_Br4923 YHRTATQVNLSGKRILEVSCGHGGGASYLTRALHPASYTGLDLNPAGIKL
TH_1636|M.thermoresistible__bu YHRTAGQADLTGKRVLEVGCGHGGGASYLMRTLGPMSYVGLDLNPAGIEF
Mb1550|M.bovis_AF2122/97 YHQTASQVDLTGKEVLEVSCGAGGGASYIARNLGPASYTGLDLNPASIDL
Rv1523|M.tuberculosis_H37Rv YHQTASQVDLTGKEVLEVSCGAGGGASYIARNLGPASYTGLDLNPASIDL
MAB_1977|M.abscessus_ATCC_1997 ALRSLIPRPLAGRSVLDAGCGSGAQCAWLLG--EGADVTGLDLSPAMVDQ
Mvan_5314|M.vanbaalenii_PYR-1 AVLIETAEKLTPGAALDIGCGVGSDAIWLAA--QGWKSTALDVSRVALDR
: . * * : . ..**.. :
MUL_4458|M.ulcerans_Agy99 ARDLAMRARADVGFVEADVYDAVQALGGERFDLVYTGLGALCWIPSISRW
MMAR_4607|M.marinum_M ARDLAMRARADVGFVEADVYDAVQALGGERFDLVYTGLGALCWIPSISRW
MSMEG_0546|M.smegmatis_MC2_155 ANDLAARAVAAVRFVESDVYDAAVVLGRESCDLVYTGIGALCWLPDIRRW
MLBr_00130|M.leprae_Br4923 CQ--KRHQLPGLEFVRGDAEN--LPFDNESFDVVIN-IEASHCYPHFPRF
TH_1636|M.thermoresistible__bu CR--KKHRLPGLEFVVGDAQD--LPFGAESFDAVIN-IESSHLYPRFSRF
Mb1550|M.bovis_AF2122/97 CR--AKHRLPGLQFVQGDAQN--LPFPDESFDAVVN-VEASHQYPDFRGF
Rv1523|M.tuberculosis_H37Rv CR--AKHRLPGLQFVQGDAQN--LPFPDESFDAVVN-VEASHQYPDFRGF
MAB_1977|M.abscessus_ATCC_1997 AR---QRCGSAAKLMVADLADD-LPLEPRSFDGVTC-SLALHYLRDWQVP
Mvan_5314|M.vanbaalenii_PYR-1 ATERGRRAGVDVNWVCSRLED--LPLPPGGFDLVTAHYPALLHSPGADAE
. : : . : : * * :
MUL_4458|M.ulcerans_Agy99 ADVFASLLRPGGRLFMREGHPFLWSLSDPRPDGLVVVEYPYFETSGIPFV
MMAR_4607|M.marinum_M ADVVASLLRPGGRLFMREGHPFLWSLSDPRPDGLVVVEYPYFETSGIPFV
MSMEG_0546|M.smegmatis_MC2_155 ATVVAQLLRPGGRLFMREGHPMLDTIDETRSDDLLVVHYPYFETAGSPFT
MLBr_00130|M.leprae_Br4923 LAEVVRVLRPGGHLAYAD----------LRPSNKVGEWEVDFANSRLQQL
TH_1636|M.thermoresistible__bu LSEVARVLRPGGHFLYAD----------ARQPHEFAEWEAALAAAPLDMV
Mb1550|M.bovis_AF2122/97 LAEVARVLRPGGHFLYTD----------SRRNPVVAEWEAALADAPLRTI
Rv1523|M.tuberculosis_H37Rv LAEVARVLRPGGHFLYTD----------SRRNPVVAEWEAALADAPLRTI
MAB_1977|M.abscessus_ATCC_1997 LASFARILRPGGWVVISLDHPFG----APLPDQRGGYFQHQLVSDTWNKA
Mvan_5314|M.vanbaalenii_PYR-1 RTLLAAVA-PGGTLLVVH-----------------------HADIDVDLA
.. : *** .
MUL_4458|M.ulcerans_Agy99 EHETYAGNGTVASPQIIHFNHGLGEIFTALTAAGLMVTGLEEHREVPWNP
MMAR_4607|M.marinum_M EHETYAGNGTVASPQIIHFNHGLGEIFTALTAAGLMVTGLEEHREVPWNP
MSMEG_0546|M.smegmatis_MC2_155 ETTTYGGEGTVSAPKGVSFNHGLGEVFTALTEAGLTVTALEEHREAPWKA
MLBr_00130|M.leprae_Br4923 SQREIN----AEVLRGIASNSQKSRDLVDRHLPAFLRFAGREFIGVQGTQ
TH_1636|M.thermoresistible__bu SARVIN----AEVVRGMEQILPVWEDVIERVAPAFLRRRVREFAPARRAW
Mb1550|M.bovis_AF2122/97 SQRDIG----AQAKRGLDANTARSQEAIGRRAPVLLAGLTRCAVRVLDWD
Rv1523|M.tuberculosis_H37Rv SQRDIG----AQAKRGLDANTARSQEAIGRRAPVLLAGLTRCAVRVLDWD
MAB_1977|M.abscessus_ATCC_1997 DVEVTQHFWRRPLGQVADAFADAGLLIERISEPRPSAEAIRRFPAELRNV
Mvan_5314|M.vanbaalenii_PYR-1 KAHGFDPADYLSHDDVIELLGEEWEVSVEKRRPRDVPAGIDGQHTHDDIV
. .
MUL_4458|M.ulcerans_Agy99 LGDAMIPSPDYDGEFILAEDRDRIPMTYTVQAIKR
MMAR_4607|M.marinum_M LGDAMIPSPDYDGEFILAEDRDRIPMTYTVQAIKR
MSMEG_0546|M.smegmatis_MC2_155 LVQGMIESTEFEGEYVLAEHPERLPLTYTIQARKP
MLBr_00130|M.leprae_Br4923 LSRYLEGGELSYRMYSFAKD---------------
TH_1636|M.thermoresistible__bu EELRTEG-STEYRMYCFTKPPEHADIP--------
Mb1550|M.bovis_AF2122/97 LRR---GGGFSYRIYLFAKD---------------
Rv1523|M.tuberculosis_H37Rv LRR---GGGFSYRIYLFAKD---------------
MAB_1977|M.abscessus_ATCC_1997 VDS---PSFIVYRLRYWGAPA--------------
Mvan_5314|M.vanbaalenii_PYR-1 LARRR------------------------------