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M. ulcerans Agy99 MUL_3321 (arsA)

annotation: arsenic-transport integral membrane protein ArsA
coordinates: 3695407 - 3696696
length: 429

MSIVAVAIFVVAYALIASERVNKTLVALAGAAIVVMLPVINSEDVFYSHETGVDWDVIFLLLGMMIIVSV
LRQTGVFEYVAICAAKRARGKPLRIMILLVIVTAVASALLDNVTTVLLIAPVTLLVCDRLVINPAPYLMA
EAFASNIGGTATLVGDPPNIVIASKGGLTFNDFLIHLAPIVVIVMAVFILMLPRLFPGSFEADPERVADV
MSLEEKEAIRDHGLLIKCGIVLLLVFTAFVANSALHVKPSMVALIGAGILVVVSRLDHSDYLSSVEWDTL
LFFVGLFIMVGALVKTGVVTQVAQMAVTATGGNTLLATMVILASSLVISGIVNNVPYAATMTPIVAELVP
VLVDKGNPDVLWWALALGTDFGGDLTAIGASANVIVLGIAKRADNPISFWEFTRKGIVVTTMSLVLAAIY
LWVRYFVLS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_3321arsA-100% (429)arsenic-transport integral membrane protein ArsA
M. ulcerans Agy99MUL_4154arsB29e-2524.58% (419) arsenical pump integral membrane protein ArsB2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2703arsA1e-17571.73% (428) arsenic-transport integral membrane protein ArsA
M. gilvum PYR-GCKMflv_1448-5e-3126.06% (426) arsenical pump membrane protein
M. tuberculosis H37RvRv2684arsA1e-17571.73% (428) arsenic-transport integral membrane protein ArsA
M. leprae Br4923MLBr_01036-1e-17770.40% (429) putative membrane transport protein
M. abscessus ATCC 19977-----
M. marinum MMMAR_2030arsA0.099.30% (429) arsenic-transport integral membrane protein ArsA
M. avium 104MAV_3579-0.077.99% (427) citrate transporter
M. smegmatis MC2 155MSMEG_0851-1e-13051.89% (424) citrate transporter
M. thermoresistible (build 8)TH_3461-2e-2825.53% (423) PUTATIVE putative Arsenical pump membrane protein
M. vanbaalenii PYR-1Mvan_5336-4e-3325.30% (423) arsenical pump membrane protein

CLUSTAL 2.0.9 multiple sequence alignment


MUL_3321|M.ulcerans_Agy99           ---MSIVAVAIFVVAYALIASERVNKTLVALAGAAIVVMLPVINSEDVFY
MMAR_2030|M.marinum_M               ---MSIVAVAIFVVAYALIASERVNKTLVALAGAAIVVMLPVINSEDVFY
MAV_3579|M.avium_104                ---MSVIAIAVFVVAYALIASDRVNKTFVALAGAAVVITLPLIRSDDVFY
Mb2703|M.bovis_AF2122/97            ---MSVVAVTIFVAAYVLIASDRVNKTMVALTGAAAVVVLPVITSHDIFY
Rv2684|M.tuberculosis_H37Rv         ---MSVVAVTIFVAAYVLIASDRVNKTMVALTGAAAVVVLPVITSHDIFY
MLBr_01036|M.leprae_Br4923          ---MSVIAITVFIVTYALIASDRVNKTLAALTGAAIVVTLPIINSEDVFY
MSMEG_0851|M.smegmatis_MC2_155      -MLAPVLALTIFVVAFWFIATERADKVKTVLVAAGLMTLLGLVPGAEVFY
Mflv_1448|M.gilvum_PYR-GCK          MALTLSVAALAAVLACALLRPR--LQAIVAGLAAALVIVAGATTWRAAVG
Mvan_5336|M.vanbaalenii_PYR-1       MELILSVAALASVLAFALLRPHRWPEAVIAVPAAALVIASGAISWDDALA
TH_3461|M.thermoresistible__bu      MAVTVASAALIAVLVSALTRPRGWPEAVVAVPAAALVVLTGAIALPDALA
                                           *    : .  :  .    :.  .  .*. :           . 

MUL_3321|M.ulcerans_Agy99           SHETGVDWDVIFLLLGMMIIVSVLRQTGVFEYVAICAAKRARGKPLRIMI
MMAR_2030|M.marinum_M               SHETGVDWDVIFLLLGMMIIVSVLRQTGVFEYVAIWAAKRARGKPLRIMI
MAV_3579|M.avium_104                SRETGIDWDVIFLLLGMMIIVSVLRQTGVFEYVAIWSAKRARGSPLRVMI
Mb2703|M.bovis_AF2122/97            SHDTGIDWDVIFLLVGMMIIVGVLRQTGVFEYTAIWAAKRARGSPLRIMI
Rv2684|M.tuberculosis_H37Rv         SHDTGIDWDVIFLLVGMMIIVGVLRQTGVFEYTAIWAAKRARGSPLRIMI
MLBr_01036|M.leprae_Br4923          SHETGIDWEVIFLLLSMMIIVSVLRQTGVFEYVAIWTAKRSHGSPLRILL
MSMEG_0851|M.smegmatis_MC2_155      SEHEGIDWNVIFLLLGMMVIVGVVKQTGLFDFLAIWAAKRSRGKPFRLMV
Mflv_1448|M.gilvum_PYR-GCK          EISE--LAPVVAFLAAVLVLARLCDDEGLFRAAGTLMARATSGGQSRLLT
Mvan_5336|M.vanbaalenii_PYR-1       EVGR--LAPVVGFLAAVLVLARLCDDVGLFHTAGVMMARATSGGQIRLLA
TH_3461|M.thermoresistible__bu      VADR--LLPVVGFLAAVLVLARLCDDEGLFRAAGAAMARVSSGNPVRLLA
                                             *: :* .::::. :  : *:*   .   *: : *   *:: 

MUL_3321|M.ulcerans_Agy99           LLVIVTAVASALLDNVTTVLLIAPVTLLVCDRLVINPAPYLMAEAFASNI
MMAR_2030|M.marinum_M               LLVIVTAVASALLDNVTTVLLIAPVTLLVCDRLVINPAPYLMAEAFASNI
MAV_3579|M.avium_104                LLVLVTALASALLDNVTTVLLIAPVTLLVCDRLAIAAAPFLMAEVFASNV
Mb2703|M.bovis_AF2122/97            LLVLVSALASALLDNVTTVLLIAPVTLLVCDRLNINTTSFLMAEVFASNI
Rv2684|M.tuberculosis_H37Rv         LLVLVSALASALLDNVTTVLLIAPVTLLVCDRLNINTTSFLMAEVFASNI
MLBr_01036|M.leprae_Br4923          LLVLVMALGSALLDNVTTVLLIAPVTLLVCERLTINAAPFLMAEVFASNI
MSMEG_0851|M.smegmatis_MC2_155      MLMIITAFASPVLDNVTIILLVAPVTVVICDRLRIPPQPYLIAEVLASNI
Mflv_1448|M.gilvum_PYR-GCK          TVFAISAAVTAILSLDATVILLTPVVLATARALAVPARPHAYATAHLANS
Mvan_5336|M.vanbaalenii_PYR-1       SVFAIAAGVTAILSLDATVVLLTPVVLATARTLAVPPRPHAYATAHLANS
TH_3461|M.thermoresistible__bu      MVFVVAAATTAILSLDATAVLLTPVVLATARRLGVAPRPHAYATAHLANS
                                     :. : *  :.:*.  :  :*::**.:  .  * : . ..  * .  :* 

MUL_3321|M.ulcerans_Agy99           GGTATLVGDPPNIVIASKGGLTFNDFLIHLAPIVVIVMAVFILMLPRLFP
MMAR_2030|M.marinum_M               GGTATLVGDPPNIVIASKGGLTFNDFLIHLAPIVVIVMAVFILMLPRLFP
MAV_3579|M.avium_104                GGAATLVGDPPNIIIASRGGLSFNDFLVHLAPIVVIVVGVLIALLPRLFP
Mb2703|M.bovis_AF2122/97            GGAATLVGDPPNIIVASRAGLTFNDFMLHLTPLVVIVLIALIAVLPRLF-
Rv2684|M.tuberculosis_H37Rv         GGAATLVGDPPNIIVASRAGLTFNDFMLHLTPLVVIVLIALIAVLPRLF-
MLBr_01036|M.leprae_Br4923          GGAATLVGDPPNIIIASRAGFSFNDFLIHLTPIVIIVTVVLSALLPRLFR
MSMEG_0851|M.smegmatis_MC2_155      GGAATLIGDPPNIIIGSRAGLTFNDFLIHMAPIVIVIFALFVVFTRVLFR
Mflv_1448|M.gilvum_PYR-GCK          ASLLLPVSNLTNLLAFSAAGLSFLHFAAAMTLPWIAAIVVEFLLLRWLFA
Mvan_5336|M.vanbaalenii_PYR-1       ASLLLPVSNLTNLLAFGAAGLSFLHFAAAMSLPWLAAIAVEFVLLRWFFA
TH_3461|M.thermoresistible__bu      ASLLLPVSNLTNLLAFGVCGLSFTRFTALMTLPWLAAIACEFVLLRRLFR
                                    ..    :.: .*::  .  *::*  *   ::   :        .   :* 

MUL_3321|M.ulcerans_Agy99           GSFEADPERVADVMSLEEKEAIRDHGLLIKCGIVLLLVFTAFVANSALHV
MMAR_2030|M.marinum_M               GSFEADPERVADVMSLEEKEAIRDHGLLIKCGIVLLLVFTAFVANSALHV
MAV_3579|M.avium_104                GAFTVDPERVADVMSLEEKEAIRDPRLLVTCGVVLLAVFAAFIAHGPLHL
Mb2703|M.bovis_AF2122/97            GSITVEADRIADVMALDEGEAIRDRGLLVKCGAVLVLVFAAFVAHPVLHI
Rv2684|M.tuberculosis_H37Rv         GSITVEADRIADVMALDEGEAIRDRGLLVKCGAVLVLVFAAFVAHPVLHI
MLBr_01036|M.leprae_Br4923          GAFAVDPERVADIMSLNEREAIRDRWLLIKCGVVLLLVFVAFIAHPVLHT
MSMEG_0851|M.smegmatis_MC2_155      KELRANHVHIEEVMALQERRAIKDMRLLVRSLIVLNIVIVGFALHSVFHV
Mflv_1448|M.gilvum_PYR-GCK          KDLATEPQR-AVSVEP--------LDVPKFTLAVVVLTLAGFAVTSLLGF
Mvan_5336|M.vanbaalenii_PYR-1       KDLAVEPRR-AAVTEP--------VEVPVFALVVLGLTLLGFAVTSLLGL
TH_3461|M.thermoresistible__bu      ADLSPAPSTGDRPAEP--------VGVPVFVLTVLGLTLTGFAVTSWLGI
                                      :                       :      *:  .: .*     :  

MUL_3321|M.ulcerans_Agy99           KPSMVALIGAGILVVVSRLDHSDYLSSVEWDTLLFFVGLFIMVGALVKTG
MMAR_2030|M.marinum_M               KPSMVALIGAGILVVVSRLDHSDYLSSVEWDTLLFFVGLFIMVGALVKTG
MAV_3579|M.avium_104                EPSLVALLGAGILVVASRLQPADYLSGVEWDTLLFFAGLFVMVGALVKTG
Mb2703|M.bovis_AF2122/97            QPSLVALLGAGMLIVVSGLTRSEYLSSVEWDTLLFFAGLFIMVGALVKTG
Rv2684|M.tuberculosis_H37Rv         QPSLVALLGAGMLIVVSGLTRSEYLSSVEWDTLLFFAGLFIMVGALVKTG
MLBr_01036|M.leprae_Br4923          GPSLVGMLGAGILIVISKLERSDYLSSVKWETLLFFAGLFIMVGALVKTD
MSMEG_0851|M.smegmatis_MC2_155      APSIVALLGAGVMLLVTDVDINEVLPEVEWPTLVFFMGLFVMVAGLTHTG
Mflv_1448|M.gilvum_PYR-GCK          SPAWAALAGALVLGVRALADRRTTMSRIVVSLDIPFLIFVLCLGVVVDAV
Mvan_5336|M.vanbaalenii_PYR-1       SPAWAALAGALVLGVRALATRHTTVTRIAAAADVPFLIFVLCLGVVVAAV
TH_3461|M.thermoresistible__bu      APAWAALAGALVLGVHGLARGRTTAEGVLSAANLPFLAFVVCLGIVVEAV
                                     *: ..: ** :: :            :     : *  :.: :. :. : 

MUL_3321|M.ulcerans_Agy99           VVTQVAQMAVTATG-GNTLLATMVILASSLVISGIVNNVPYAATMTPIVA
MMAR_2030|M.marinum_M               VVTQVAQMAVTATG-GNTLLATMVILAASLVISGIVNNVPYAATMTPIVA
MAV_3579|M.avium_104                VVKHLARLAITATG-GNTLTATMVILVASVVISGIVDNVPYAATMAPVVA
Mb2703|M.bovis_AF2122/97            VVNDLARAATQLTG-GNIVATAFLILGVSAPISGIIDNIPYVATMTPLVA
Rv2684|M.tuberculosis_H37Rv         VVNDLARAATQLTG-GNIVATAFLILGVSAPISGIIDNIPYVATMTPLVA
MLBr_01036|M.leprae_Br4923          VVNQLARATTTLTG-GHELLTVVLTLGVSTLVSSIIDNIPYVATMTPIVS
MSMEG_0851|M.smegmatis_MC2_155      VIGELGSVAQSAFG-DNWLGAATALLFGSSIAGAFIDNIPYTATMTPVVE
Mflv_1448|M.gilvum_PYR-GCK          MRNGLESAMQQVIPDGHGLLALLGIAAVAALLSNVVNNLPAVLVLLPLVA
Mvan_5336|M.vanbaalenii_PYR-1       MRNGLESAMRDAIPEGQGLAALLGIAAVAAVLSNVVNNLPAVLVLLPLVT
TH_3461|M.thermoresistible__bu      RTAGLDGALAAVLPDPGSLWGLLGIAAAAAVLANAVNNLPAVLALLPLVS
                                        :             :         :   .  ::*:* . .: *:* 

MUL_3321|M.ulcerans_Agy99           ELVPVLVDKGNPDVLWWALALGTDFGGDLTAIGASANVIVLGIAKRADNP
MMAR_2030|M.marinum_M               ELVPVLVDKGNPDVLWWALALGTDFGGNLTAIGASANVIVLGIAKRADNP
MAV_3579|M.avium_104                DLVPALGDHANPAVLWWSLALGTDFGGNLTAIGASANIVLLGIARRADNP
Mb2703|M.bovis_AF2122/97            ELVAVMGGQPSTDTPWWALALGADFGGNLTAIGASANVVMLGIARRAGAP
Rv2684|M.tuberculosis_H37Rv         ELVAVMGGQPSTDTPWWALALGADFGGNLTAIGASANVVMLGIARRAGAP
MLBr_01036|M.leprae_Br4923          ELVASMPDQSHTDILWWALALGADFGGNLTAVGASANVVMLEIAKSAGTP
MSMEG_0851|M.smegmatis_MC2_155      SMVADAPDMVTGNALWWAFALGACFSGNGTAIAASANVVAIGIAKRAGHP
Mflv_1448|M.gilvum_PYR-GCK          GSGPAAV---------LAVLIGVNIGPNLTYVGSLANLLWRSVVR-RDVK
Mvan_5336|M.vanbaalenii_PYR-1       PIGPAAV---------LAVLIGVNIGPNLTYVGSLANLLWRSVVR-RDMR
TH_3461|M.thermoresistible__bu      AAGPAAV---------LAVLIGVNIGPNLSYLGSLSNLLWRNAVQ-PDIP
                                       .             :. :*. :. : : :.: :*::    .:  .  

MUL_3321|M.ulcerans_Agy99           ISFWEFTRKGIVVTTMSLVLAAIYLWVRYFVLS-
MMAR_2030|M.marinum_M               ISFWEFTRKGIVVTTMSLVLAAIYLWVRYFVLS-
MAV_3579|M.avium_104                ISFWEFTRKGVVVTAVSVALSALYLWLRYFVWG-
Mb2703|M.bovis_AF2122/97            ISFWEFTRKGAVVTAVSIALAAIYLWLRYFVLLH
Rv2684|M.tuberculosis_H37Rv         ISFWEFTRKGAVVTAVSIALAAIYLWLRYFVLLH
MLBr_01036|M.leprae_Br4923          ISFWEFTRKGIAVTVISIALAGIYLWLRYLVMS-
MSMEG_0851|M.smegmatis_MC2_155      ISFWQFTRYGIVVTFLSTALAWVYVWLRYF----
Mflv_1448|M.gilvum_PYR-GCK          AGFGEFSRIGVVTTPLVLVAAVLGLWTYVRLIGL
Mvan_5336|M.vanbaalenii_PYR-1       VGFAEFSRAGLVTAPLTLVAAVLGLWAWIQLFGL
TH_3461|M.thermoresistible__bu      AGFGEFSRIGLMTAPLTLVASVLALWVSLQLFGT
                                     .* :*:* *  .: :  . : : :*