For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SFVVVDPEMVAATAADLANIGSTIGAANGAAAATTRAVLAAGGDEISAAVAACFEAQAEAYRTFGAHTAA LHDQIVRALTAGAGGYSAVEAANTSLQQAANLVTSPVQTLTGRPLFGNGADATTPGANGGNGGWLIGSGG DGAAGGVAGQAGGNGGSAGLIGDGGNGGTGGFGAAGGTGGAGGMLFGNGGAGGVGVTAGLGGNGGAGGSV GLWGHGGNGGIGGAGGAGADGVNPLPADAPFSHADSGQQGHDVIDGTAAGGHAGADGTTAGEIGGVGGRG GGAWAQSPTGTPNVTGGAGGAGGAAGDGAFGGGPYHTGQGGVGGDGGNGGNGGAGGAGGLIGHSGGSGLG GAAGGGGSGGAGGLGGAGGFGEGGGAAAGANGATGATGNSGHSGQAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3741 | - | - | 100% (398) | N-term PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_3062 | - | 9e-96 | 49.31% (436) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_0212 | - | 2e-94 | 48.44% (450) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0896c | PE_PGRS15 | 1e-104 | 50.58% (433) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 2e-64 | 47.35% (283) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3595c | PE_PGRS59 | 1e-111 | 53.85% (403) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 1e-10 | 34.57% (162) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 3e-31 | 38.46% (312) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_3816 | - | 0.0 | 83.17% (416) | PE-PGRS family protein, PE_PGRS59 |
| M. avium 104 | MAV_4827 | - | 3e-20 | 37.57% (189) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-57 | 42.41% (323) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 2e-41 | 39.71% (277) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 2e-64 | 40.25% (395) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3741|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3816|M.marinum_M --------------------------------------------------
Mb0896c|M.bovis_AF2122/97 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------------------MSIIDFILNLFRDPV
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ---------------------------------MAGKARVHELAKELGVT
MUL_3741|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3816|M.marinum_M --------------------------------------------------
Mb0896c|M.bovis_AF2122/97 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 EAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQSQWVNT
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 SKEVLARLNEQGEFVKSASSTVEAPVARRLRESFGGIKPAADKGAEQVAT
MUL_3741|M.ulcerans_Agy99 ------------------------------------------MSFVVVDP
MMAR_3816|M.marinum_M ------------------------------------------MSFVVVDP
Mb0896c|M.bovis_AF2122/97 ------------------------------------------MSYVLATP
Rv3595c|M.tuberculosis_H37Rv ------------------------------------------MSFVIAVP
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDFASHNP
MAV_4827|M.avium_104 -----------------------------MNIVLGVSMAPSSIQMVVLEG
MLBr_01556|M.leprae_Br4923 KAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQVDHSAAVVPIVAGEG
MUL_3741|M.ulcerans_Agy99 ----------------------------------------EMVAATAADL
MMAR_3816|M.marinum_M ----------------------------------------EMVAATAADL
Mb0896c|M.bovis_AF2122/97 ----------------------------------------EMVAAAANNL
Rv3595c|M.tuberculosis_H37Rv ----------------------------------------EFLSAAATDL
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu ------------------------------------------VDGDGG--
MAB_4284c|M.abscessus_ATCC_199 IASG------------------------------------NQVMSPSGNV
MAV_4827|M.avium_104 EYADG-----------------------------------ATVEEDAIDV
MLBr_01556|M.leprae_Br4923 PSTAHR----------------------------------EELAPPAGQP
:
MUL_3741|M.ulcerans_Agy99 AN----------------------IGSTIG-----------AANGAAAAT
MMAR_3816|M.marinum_M AN----------------------IGSTIG-----------AANGAAAAT
Mb0896c|M.bovis_AF2122/97 AQ----------------------IGSTLS-----------AANAAALAP
Rv3595c|M.tuberculosis_H37Rv AN----------------------LGSTIS-----------AANAAASIP
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu ------------------------------------------SGGRTGLF
MAB_4284c|M.abscessus_ATCC_199 DSFNRG----------------PLLDLSFGDLQFGNRDTTAIGDGAVAVG
MAV_4827|M.avium_104 TG---------------------------------------ADDAATASA
MLBr_01556|M.leprae_Br4923 SE---------------------QPGVPLP-----------GQQGTPAAP
.
MUL_3741|M.ulcerans_Agy99 TR-------AVLAAGGDEISAAVAACFEAQAEAYRTFG------------
MMAR_3816|M.marinum_M TR-------AVLAAGGDEISAAVAACFEAQAEAYQTFG------------
Mb0896c|M.bovis_AF2122/97 TT-------GVLAAGADEVSAAVASLFSGHAQAYQTLG------------
Rv3595c|M.tuberculosis_H37Rv TT-------GVLAAGADDVSAAIAALFGAHAQAYQTIS------------
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
TH_3810|M.thermoresistible__bu SK---------LSRGGDGGDGGLGGN-GGHGGGTGIIS------------
MAB_4284c|M.abscessus_ATCC_199 GS---NSGPIASGQGSTAVNGDVRDSNIINADHGSNVGVDQSQTRVGGDY
MAV_4827|M.avium_104 PDR---VISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRI
MLBr_01556|M.leprae_Br4923 HPG-----HPGMPTGPHPGPAPKPGGRPPRVGNNPFSS----AQSVARPI
. .
MUL_3741|M.ulcerans_Agy99 -----AHTAALHDQIVRALTAGAGGYSAVEAANTS--------LQQAANL
MMAR_3816|M.marinum_M -----AHTAALHDQIVRALTAGAGGYSAVEAANTS--------LQQAANL
Mb0896c|M.bovis_AF2122/97 -----TQAAAFHERFIQALSTAAGAYGSAEAANASP-------LQQALNV
Rv3595c|M.tuberculosis_H37Rv -----AQAATFHAQFVQTLSAGAGAYANAEAANVQ---------QSLLNA
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
TH_3810|M.thermoresistible__bu -------------LLSLAGNGGNGGNGYRTTDNNA---------LDGGHG
MAB_4284c|M.abscessus_ATCC_199 TNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTE
MAV_4827|M.avium_104 DNVMLVSAFLAAAALAQNVGGAMGYERTAVLLVEPDTATLAVVETSDGSI
MLBr_01556|M.leprae_Br4923 PRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGR
. .
MUL_3741|M.ulcerans_Agy99 VTSPVQTLTGRPLFGNGADAT--TPGANG--GNGG-------------WL
MMAR_3816|M.marinum_M VTSPVQTLTGRPLFGNGADAT--TPGANG--GNGG-------------WL
Mb0896c|M.bovis_AF2122/97 INAPTQTLLGRPLIGNGTNGAP-GTGQAG--GPGG-------------LL
Rv3595c|M.tuberculosis_H37Rv INAPTQALLGRPLIGDGADGT--APGQNG--GAGG-------------LL
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
TH_3810|M.thermoresistible__bu GNGGNVGFFS--LFNLGGAGGWGGSGVDGVDVVGG---------------
MAB_4284c|M.abscessus_ATCC_199 IGSHNQANIGTSTSAGGSAAVGGNAGLAGNAGLAG--------------N
MAV_4827|M.avium_104 PDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLPGG-----------LLL
MLBr_01556|M.leprae_Br4923 SDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGG--------------G
. * *
MUL_3741|M.ulcerans_Agy99 IGSGGDGAAGGVAGQAG---------------------------------
MMAR_3816|M.marinum_M IGSGGDGAAGGVAGQAG---------------------------------
Mb0896c|M.bovis_AF2122/97 YGNGGNGGSGG-VGQAG---------------------------------
Rv3595c|M.tuberculosis_H37Rv YGNGGNGAAGVNAGIAG---------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
TH_3810|M.thermoresistible__bu NPDGGTPGAHGESHTPG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAGLAGNAGLAG---------------------------------
MAV_4827|M.avium_104 VGSGVDVAPLKQVLQTT---------------------------------
MLBr_01556|M.leprae_Br4923 GRPGQRGGAAGAFGRPGGAPRRGRKSKRQKRQEYDS--------------
.
MUL_3741|M.ulcerans_Agy99 ------GNGGSAGLIGDG-GNGGTGGFG----------------------
MMAR_3816|M.marinum_M ------GSGGSAGLIGDG-GNGGTGGFG----------------------
Mb0896c|M.bovis_AF2122/97 ------GAGGSAGLIGIG-GTGGAGGAG----------------------
Rv3595c|M.tuberculosis_H37Rv ------GSGGAAGLIGNG-GSGGAGGAG----------------------
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTG-ANGGAGGVG-----GVGGTGAAGAAGGAGGL
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVG-GNGGAGQAG-----GIGGTGAAGAAGQAGTA
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAG-GNGGTGGTGRVIAEGTGSTAEGTATGGDGGH
TH_3810|M.thermoresistible__bu ---VYTDRQGEDGEDGTGTGIGGRGGNG----------------------
MAB_4284c|M.abscessus_ATCC_199 ----NAGLAGNAGLAGNAGLAGNAGLAG----------------------
MAV_4827|M.avium_104 --TFLDVSVAEEPETALARGAALAAANAP---------------------
MLBr_01556|M.leprae_Br4923 --MQAPVVGGVRLPHGNGETIRLARGASLS--------------------
. . . .
MUL_3741|M.ulcerans_Agy99 ------------------------------------AAGGTGGAGGM---
MMAR_3816|M.marinum_M ------------------------------------AAGGTGGAGGM---
Mb0896c|M.bovis_AF2122/97 ------------------------------------AVGGVGGNGGW---
Rv3595c|M.tuberculosis_H37Rv ------------------------------------AAGGSGGQGGL---
Mflv_5091|M.gilvum_PYR-GCK GETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGA
Mvan_1264|M.vanbaalenii_PYR-1 GETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGV
MSMEG_0868|M.smegmatis_MC2_155 STGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEI
TH_3810|M.thermoresistible__bu --------------------------------------GSSSGTHPMAE-
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------NAGLAGNAGLAG-
MAV_4827|M.avium_104 -----------------------------------LFASSTAALAYAQDP
MLBr_01556|M.leprae_Br4923 ----------------------------------DFAEKIDANPAALVQA
.
MUL_3741|M.ulcerans_Agy99 -------------------------------------LFG----------
MMAR_3816|M.marinum_M -------------------------------------LFG----------
Mb0896c|M.bovis_AF2122/97 -------------------------------------LYG----------
Rv3595c|M.tuberculosis_H37Rv -------------------------------------LYG----------
Mflv_5091|M.gilvum_PYR-GCK G----------STGAVGG-------VGGKG----IQGGQG----------
Mvan_1264|M.vanbaalenii_PYR-1 G----------ATGGAGG-------VGGKG----IQGGQG----------
MSMEG_0868|M.smegmatis_MC2_155 YSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGT
TH_3810|M.thermoresistible__bu --------------------------------------DG----------
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------NAG----------
MAV_4827|M.avium_104 -------------------------------------GTG-----AVDQY
MLBr_01556|M.leprae_Br4923 LFN-------------------------LGEMVTATQSVG----------
*
MUL_3741|M.ulcerans_Agy99 ----NGG---AGGVG-------------------------------VTAG
MMAR_3816|M.marinum_M ----NGGNGGAGGVG-------------------------------VTAG
Mb0896c|M.bovis_AF2122/97 ----NGG---AGGLGGT-------------------------GVAGVNGG
Rv3595c|M.tuberculosis_H37Rv ----NGG---AGGNG---------------------------GAATIPGG
Mflv_5091|M.gilvum_PYR-GCK ---LQGGKGGDGGAGGKGGDADSMGS------------------AGATGG
Mvan_1264|M.vanbaalenii_PYR-1 ---LQGGQGGDGGTGGTGGDATSMGE------------------AGATGG
MSMEG_0868|M.smegmatis_MC2_155 AKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGA
TH_3810|M.thermoresistible__bu ----EHVKALDGRPGLD----------------------------GGNGS
MAB_4284c|M.abscessus_ATCC_199 ---LAGNAGLAGNAG-----------------------------LAGNAG
MAV_4827|M.avium_104 SLPDYLYVPVDPEPGDD---------------------------ELAYSA
MLBr_01556|M.leprae_Br4923 ---DETLELLGSEMNYNVQVVSPEDEDRE-------------LLEPFDLT
.
MUL_3741|M.ulcerans_Agy99 LGGNGGAGGSVGLWG-----------------------------------
MMAR_3816|M.marinum_M LGGNGGAGGSAGLWG-----------------------------------
Mb0896c|M.bovis_AF2122/97 MGAAGGAGGNAYLFG-----------------------------------
Rv3595c|M.tuberculosis_H37Rv NGGAGGAGGNAWLFG-----------------------------------
Mflv_5091|M.gilvum_PYR-GCK KGGNGGNGGRGGLFG---------------KGGNAGNGAD----------
Mvan_1264|M.vanbaalenii_PYR-1 KGGNGGNGGRGSLFG---------------RGGNAGNGGN----------
MSMEG_0868|M.smegmatis_MC2_155 VGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNG
TH_3810|M.thermoresistible__bu HGGNGGHGGRGGFLG-----------------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAGLAG-----------------------------------
MAV_4827|M.avium_104 VGEEDAESPTVVIEKLFLP-------------------------------
MLBr_01556|M.leprae_Br4923 YGEDQGDEDELQVRPPVVTVMG----------------------------
. . .
MUL_3741|M.ulcerans_Agy99 -----------------------HGG------------------------
MMAR_3816|M.marinum_M -----------------------HGG------------------------
Mb0896c|M.bovis_AF2122/97 -----------------------SGG------------------------
Rv3595c|M.tuberculosis_H37Rv -----------------------NGG------------------------
Mflv_5091|M.gilvum_PYR-GCK ------------GGTGGAGGAGGTGG-TGGAGGTGG--------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------GGTGGNGGNGGTGG-TGGNGGTGG--------------
MSMEG_0868|M.smegmatis_MC2_155 PAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTG
TH_3810|M.thermoresistible__bu -----------------------IGG------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------------------NAG------------------------
MAV_4827|M.avium_104 ------------EDSEPRRRPVLLVG------------------------
MLBr_01556|M.leprae_Br4923 ---------------------HVDHG---------------------KTR
*
MUL_3741|M.ulcerans_Agy99 ---NGGIGGAGGAGADGVNPLPADAPFSHADSGQQ---GHDVIDGTAAGG
MMAR_3816|M.marinum_M ---NGGIGGAGGAGADGVNPVPADAPFSYADSGQQ---GHDVIDGTAAGG
Mb0896c|M.bovis_AF2122/97 ---AGGQGGMGAAGADGVNPTPTGTADAGSTGTDQTL-GGNAIGGNGGPG
Rv3595c|M.tuberculosis_H37Rv ---AGGLGAAGAAGAAGVNP-LTVPAGQGS------------MGNNGEPG
Mflv_5091|M.gilvum_PYR-GCK ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG---GTGGTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 QTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSE--GEGGTGGHGGDG
TH_3810|M.thermoresistible__bu ---SGGWGGHGGNGGD-----TDADGGNGGD------------GGNGGSA
MAB_4284c|M.abscessus_ATCC_199 ---LAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAG---NAAVAGNAAVG
MAV_4827|M.avium_104 ----SGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAP
MLBr_01556|M.leprae_Br4923 LLDTIRKANVREAEAGGITQHIGAYQVGVDLDGSERLITFIDTPGHEAFT
.
MUL_3741|M.ulcerans_Agy99 HAGADGTTAGEIGG--------VGGRGGGAWAQSPTG------TPNVTGG
MMAR_3816|M.marinum_M HAGADGTTAGEIGG--------VGGRGGAAWAQSPTG------TPNVTGG
Mb0896c|M.bovis_AF2122/97 DAGDAMTSGGAGGSGGNAVSTVNGDAVGGEGGKGGEG------AYGGAGG
Rv3595c|M.tuberculosis_H37Rv GPGQPGTEFGQTG---------------------------------GTGG
Mflv_5091|M.gilvum_PYR-GCK GKGGTGGTGGAGGTG-------GDGGTGGTGGTGGTG---------GTGG
Mvan_1264|M.vanbaalenii_PYR-1 GKGGTGGTGGDGGTG-------GTGGTGGTGGTGGTG---------GTGG
MSMEG_0868|M.smegmatis_MC2_155 GRGGDGALGGNGGTGGVG---LGNGGKGGNGGNGGNGGTYVDPSHTGAGG
TH_3810|M.thermoresistible__bu GRGGTGGLRGVFGIN------------GGNG----------------RAG
MAB_4284c|M.abscessus_ATCC_199 GVLNTGVSGAIGGSS----------HVGGAINESLGG----------SGS
MAV_4827|M.avium_104 APPPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAPPPAAPPLPEAPP
MLBr_01556|M.leprae_Br4923 AMRARGAKATDIAILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDK
MUL_3741|M.ulcerans_Agy99 AGG-----------------------------------------------
MMAR_3816|M.marinum_M AGGGGGDGGS---------GAMGGGGGAGGDATAGTGAVATGGAGGDG--
Mb0896c|M.bovis_AF2122/97 AGGSAASIGN---------AAIGGNGGAGGNAQAPGGVGGAGGEGGDA--
Rv3595c|M.tuberculosis_H37Rv TGGTGLSVG-----------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TGGTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG----
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG----
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALI
TH_3810|M.thermoresistible__bu LGGRGXXX------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGSTAVGGG----------------------------------------
MAV_4827|M.avium_104 IPAAPPVVPVP---------------------------------------
MLBr_01556|M.leprae_Br4923 EGADPAKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTA
.
MUL_3741|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3816|M.marinum_M -------------GAGGAGAIGGAGGAGGSAGTVLGTG------------
Mb0896c|M.bovis_AF2122/97 -------------QVGTNSPSNAEAGNGGSGGNGFDS-------------
Rv3595c|M.tuberculosis_H37Rv ----------------------------GTGG------------------
Mflv_5091|M.gilvum_PYR-GCK -------------TGGTGGQGG-LGGGGGTG-------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------TGGTGGQGG-LGGVGGTG-------------------
MSMEG_0868|M.smegmatis_MC2_155 RATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 DAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRG------------
MUL_3741|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3816|M.marinum_M ---SAHGGAGGAGGAGGAGAAGGIGGAGGSADVNANVFPGQSATGGNGGM
Mb0896c|M.bovis_AF2122/97 ---FASGGTGGAGGTGGAGGRGG-------------LLIGDGGAGGAGGV
Rv3595c|M.tuberculosis_H37Rv -----TGGTGGTGGAGGSGGRGG-------------LLVGDGGAGGIGGT
Mflv_5091|M.gilvum_PYR-GCK ----GQGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL
Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGL
MSMEG_0868|M.smegmatis_MC2_155 TATDGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGL
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------AHTGVGGGVSTGVGVGSHVGGG--------ISESLGGSGSVGGS
MAV_4827|M.avium_104 -VVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSP
MLBr_01556|M.leprae_Br4923 -----TLRIGDSVVAGDAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSV
MUL_3741|M.ulcerans_Agy99 --------------------------------------------------
MMAR_3816|M.marinum_M GGRGGDGVAAGLAGDGGNGGVGGRGGVLFGDGGIGGAGGGGGIGGTGAVG
Mb0896c|M.bovis_AF2122/97 GGTGGSGAPGGGGAGGDGGAANTDSAGSSRKAFGGDGGVGGDGASALGTG
Rv3595c|M.tuberculosis_H37Rv GGEGGIGARGG---------------------TGGQGGMGG--------A
Mflv_5091|M.gilvum_PYR-GCK GGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GS
Mvan_1264|M.vanbaalenii_PYR-1 GGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GS
MSMEG_0868|M.smegmatis_MC2_155 GGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQS
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 TAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVG--GG
MAV_4827|M.avium_104 PQVGGTVPQSPPQHQTPPGEGTPPKPDGPGNYGGGHVPTPGAGGSGGSGG
MLBr_01556|M.leprae_Br4923 PGAGDNFLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDSALKE
MUL_3741|M.ulcerans_Agy99 ----AGGAAGDGAFGGGPYHTG-QGGVGGDGG---------------NGG
MMAR_3816|M.marinum_M GGGGAGGAAGDGAFGGGPFHTG-QGGVGGDGGD------GGAGGDGGNGG
Mb0896c|M.bovis_AF2122/97 GEGGIGGQGGNGGAGGLLIGNGGAGGVGGTAG------------AGGTGG
Rv3595c|M.tuberculosis_H37Rv GQPGVGGDAGDGGNG----------GIGGDGG------------AGGDGG
Mflv_5091|M.gilvum_PYR-GCK GSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAG
Mvan_1264|M.vanbaalenii_PYR-1 GSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASG
MSMEG_0868|M.smegmatis_MC2_155 GYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTA
TH_3810|M.thermoresistible__bu ----XGGGVGAAVRSG-------NGVFSGGGG----------------TP
MAB_4284c|M.abscessus_ATCC_199 AHTGVGGGVNTGVGVGSHVGGGISESLGGSGS------------VGGSTA
MAV_4827|M.avium_104 GHVPTPGAGGSGGSGGGHVPTPGTGGPGGTGGS-----GGGHVPTPGAGT
MLBr_01556|M.leprae_Br4923 TSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVN
MUL_3741|M.ulcerans_Agy99 NGGAGGAGGLIGHSGGSG-------------------------LGGAAG-
MMAR_3816|M.marinum_M NGGAGGAGGLIGHSGGSG-------------------------LGGAAG-
Mb0896c|M.bovis_AF2122/97 SGGAGGAGGAGGGGTNSGP---------------------GAAFGGNGN-
Rv3595c|M.tuberculosis_H37Rv AGGAGGAGGLFGVSGSSG-------------------------LGGAAG-
Mflv_5091|M.gilvum_PYR-GCK KAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQ
Mvan_1264|M.vanbaalenii_PYR-1 AQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQ
MSMEG_0868|M.smegmatis_MC2_155 TGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGK
TH_3810|M.thermoresistible__bu SAGFGVPTTIQFPAGSCT--------------------------------
MAB_4284c|M.abscessus_ATCC_199 VGGGAHTSAINDALGGSGS-------------------------------
MAV_4827|M.avium_104 PGGSGGGHLPFPGAGSTPG-------------------------GSGGG-
MLBr_01556|M.leprae_Br4923 LASASDAIIIGFNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRG
.
MUL_3741|M.ulcerans_Agy99 ----------------------------------------GGGSGGAGG-
MMAR_3816|M.marinum_M ----------------------------------------GGGSGGAGG-
Mb0896c|M.bovis_AF2122/97 ----------------------------------------TGGNGGNGGA
Rv3595c|M.tuberculosis_H37Rv ----------------------------------------SGGNGGGGGE
Mflv_5091|M.gilvum_PYR-GCK GAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG-
Mvan_1264|M.vanbaalenii_PYR-1 GAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG-
MSMEG_0868|M.smegmatis_MC2_155 GADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGN
TH_3810|M.thermoresistible__bu ----------------------------------------SRAVSREGIM
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------VGGSTAVGGG
MAV_4827|M.avium_104 -------------------------------------HLPTPGAGTPGGG
MLBr_01556|M.leprae_Br4923 MLKPIYEENQLGRAEIR-------------------ALFRSSKVGIIAGC
.
MUL_3741|M.ulcerans_Agy99 ----------------LGGAGG----------------FGEGGGAAAGAN
MMAR_3816|M.marinum_M ----------------LGGAGG----------------FGEGGGAAAGAN
Mb0896c|M.bovis_AF2122/97 -------------PGALGGKGGSGGLIGRAGSDGGVGAGGAGGAGGAGGT
Rv3595c|M.tuberculosis_H37Rv -------------PGVAGSPG--------------VGPAGRGGDGNLGQF
Mflv_5091|M.gilvum_PYR-GCK ----------AGGEGGEGGDGGKGGAGAE---------GGAGGGGGAGGS
Mvan_1264|M.vanbaalenii_PYR-1 ----------AGGEGGEGGAGGAGGDGSE---------GGAGGSGGAGGS
MSMEG_0868|M.smegmatis_MC2_155 TSVWKSGGQTADGEHNTGGNGGNGGDGSEPGP-GGNGAGGAGGNGGTGGT
TH_3810|M.thermoresistible__bu P-------------------------------------SSRAASARAGAA
MAB_4284c|M.abscessus_ATCC_199 ------------AHTSAINESMNSSINASHSSSMNESFGSSMGSHGAAGT
MAV_4827|M.avium_104 ----------------LGGFGGGHAPAPG---------GGLGGGGGHAPA
MLBr_01556|M.leprae_Br4923 IIS----------SGVVRRNAKVRLLRDNIVVTDNLTVTSLRREKDDVTE
.
MUL_3741|M.ulcerans_Agy99 GATG-----------------ATGNSGHSGQAG-
MMAR_3816|M.marinum_M GATG-----------------ATGNSGHSGQAG-
Mb0896c|M.bovis_AF2122/97 GGEGGTGGDGKTTDGNPGMGGSPGSAGQPGQPG-
Rv3595c|M.tuberculosis_H37Rv GPEG-----------------APGQPGQPGQPG-
Mflv_5091|M.gilvum_PYR-GCK GAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 GTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 TAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu CASS-----------------TSRSRRSFCCSRA
MAB_4284c|M.abscessus_ATCC_199 GFEAQG--------HAQGHASETAHTTLPGAEHH
MAV_4827|M.avium_104 PGGGLG---------GFGGGHSGGGLGGLGGGHK
MLBr_01556|M.leprae_Br4923 VREGFECGMTLGYSDIKEGDVIESYELVEKQRA-
.