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MSYVLATPEMVAAAANNLAQIGSTLSAANAAALAPTTGVLAAGADEVSAAVASLFSGHAQAYQTLGTQAA AFHERFIQALSTAAGAYGSAEAANASPLQQALNVINAPTQTLLGRPLIGNGTNGAPGTGQAGGPGGLLYG NGGNGGSGGVGQAGGAGGSAGLIGIGGTGGAGGAGAVGGVGGNGGWLYGNGGAGGLGGTGVAGVNGGMGA AGGAGGNAYLFGSGGAGGQGGMGAAGADGVNPTPTGTADAGSTGTDQTLGGNAIGGNGGPGDAGDAMTSG GAGGSGGNAVSTVNGDAVGGEGGKGGEGAYGGAGGAGGSAASIGNAAIGGNGGAGGNAQAPGGVGGAGGE GGDAQVGTNSPSNAEAGNGGSGGNGFDSFASGGTGGAGGTGGAGGRGGLLIGDGGAGGAGGVGGTGGSGA PGGGGAGGDGGAANTDSAGSSRKAFGGDGGVGGDGASALGTGGEGGIGGQGGNGGAGGLLIGNGGAGGVG GTAGAGGTGGSGGAGGAGGAGGGGTNSGPGAAFGGNGNTGGNGGNGGAPGALGGKGGSGGLIGRAGSDGG VGAGGAGGAGGAGGTGGEGGTGGDGKTTDGNPGMGGSPGSAGQPGQPG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0896c | PE_PGRS15 | - | 100% (608) | PE-PGRS family protein |
M. bovis AF2122 / 97 | Mb2878 | PE_PGRS48 | 0.0 | 65.11% (622) | PE-PGRS family protein |
M. bovis AF2122 / 97 | Mb2667c | PE_PGRS46 | 0.0 | 49.02% (763) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_5091 | - | 1e-118 | 49.91% (537) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv0872c | PE_PGRS15 | 0.0 | 99.83% (606) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01183 | - | 6e-14 | 39.58% (96) | hypothetical protein MLBr_01183 |
M. abscessus ATCC 19977 | MAB_4284c | - | 3e-50 | 32.38% (522) | hypothetical protein MAB_4284c |
M. marinum M | MMAR_2490 | - | 0.0 | 58.79% (626) | PE-PGRS family protein, PE_PGRS15_1 |
M. avium 104 | MAV_4827 | - | 7e-23 | 38.42% (190) | hypothetical protein MAV_4827 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-94 | 41.63% (615) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 2e-39 | 38.72% (297) | PUTATIVE - |
M. ulcerans Agy99 | MUL_0572 | - | 1e-159 | 46.41% (765) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-113 | 43.67% (577) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb0896c|M.bovis_AF2122/97 -------------------------------------------------- Rv0872c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2490|M.marinum_M -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES MUL_0572|M.ulcerans_Agy99 -------------------------------------------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------- Mb0896c|M.bovis_AF2122/97 --------MSYVLATPEMVAAAANNLAQIGSTLSAANAAALAPTTGVLAA Rv0872c|M.tuberculosis_H37Rv --------MSYVLATPEMVAAAANNLAQIGSTLSAANAAALAPTTGVLAA MMAR_2490|M.marinum_M --------MSFVITAPELISAAATDLAGIGSTISAANAAASASTTAVAAA TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP-- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT MUL_0572|M.ulcerans_Agy99 --------MSYVVAIPDMLASAAADVAGIGSSVGAANTAAVGATTGVMAA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------MSIIDFILNLFRDPVEAASYVADPEAALANAGLSAVSAAQVG MAV_4827|M.avium_104 ----MNIVLGVSMAPSSIQMVVLEGEYADGATVEEDAIDVTGADDAATAS Mb0896c|M.bovis_AF2122/97 GADEVSAAVASLFSGHAQAYQTLGTQAAAFHERFIQALSTAAGAYGSAEA Rv0872c|M.tuberculosis_H37Rv GADEVSAAVASLFSGHAQAYQTLGTQAAAFHERFIQALSTAAGAYGSAEA MMAR_2490|M.marinum_M AADEVSTAVATLFGAHAQQYQSLGSQMAAFHDDFVRILASGSNLYATAEA TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA MUL_0572|M.ulcerans_Agy99 ADDEVSVAIAALFSGHGQAYQAISAQAAAFHDQFLRALTGAGGAYAAAEA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AVMPVVAESVASNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILSP MAV_4827|M.avium_104 APDRVISAILGTREGAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDN Mb0896c|M.bovis_AF2122/97 AN-------------------------------------ASPLQQALNVI Rv0872c|M.tuberculosis_H37Rv AN-------------------------------------ASPLQQALNVI MMAR_2490|M.marinum_M TN-------------------------------------ASPLQPLLDLI TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP MUL_0572|M.ulcerans_Agy99 AN-------------------------------------ASPLQAAEQEV MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 SL-------------------------------------LSPRDNDFLSH MAV_4827|M.avium_104 VMLVS-----------------------------------AFLAAAALAQ Mb0896c|M.bovis_AF2122/97 N---------------------APTQTLLG--------RPLIGNGTNGAP Rv0872c|M.tuberculosis_H37Rv N---------------------APTQTLLG--------RPLIGNGTNGAP MMAR_2490|M.marinum_M N---------------------APTQAILG--------RPLIGNGSNGTY TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA MUL_0572|M.ulcerans_Agy99 LAVIN-----------------APTNALLG--------RPLIGNGTDGLA MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 N---------------------DTDFASHN--------PIASGNQVMSPS MAV_4827|M.avium_104 N-----------------------VGGAMG----------YERTAVLLVE Mb0896c|M.bovis_AF2122/97 GTGQAGGPGGLLYGNGGNGGSGGVG-QAGGAGGSAGLIG-IGGTGGAGGA Rv0872c|M.tuberculosis_H37Rv GTGQAGGPGGLLYGNGGNGGSGGVG-QAGGAGGSAGLIG-IGGTGGAGGA MMAR_2490|M.marinum_M -PGQDGRDGGLLIGNGGNGAAGDFG-QAGGGGGSAGLFG-DGGNGGTGGA TH_3810|M.thermoresistible__bu -------------------------------------------------V Mflv_5091|M.gilvum_PYR-GCK QN------GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLG Mvan_1264|M.vanbaalenii_PYR-1 QN------GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLG MSMEG_0868|M.smegmatis_MC2_155 DNPNGG-TGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWA MUL_0572|M.ulcerans_Agy99 GTGAAGGAGGLLWGNGGNGG-SGAAGQAGGAGGAAGLIGTGGAGGMGGAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GNVDSFNRGPLLDLSFGDLQFGNRDTTAIGDG--AVAVGGSNSGPIASGQ MAV_4827|M.avium_104 PDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKLESLP Mb0896c|M.bovis_AF2122/97 GAVGGVGGNGG--WLYGNGGAGGLGGTGVAGVNGGMG----AAGGAGGNA Rv0872c|M.tuberculosis_H37Rv GAVGGVGGNGG--WLYGNGGAGGLGGTGVAGVNGGMG----AAGGAGGNA MMAR_2490|M.marinum_M GSAGGNGGTGG--LLFGNGGNGGMGGTATLGFNGGMA----GAGGNGGSA TH_3810|M.thermoresistible__bu DGDGGSGGRTGLFSKLSRGGDGGDGGLG-------------GNGGHGGGT Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGAT Mvan_1264|M.vanbaalenii_PYR-1 SGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGAT MSMEG_0868|M.smegmatis_MC2_155 GLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGT MUL_0572|M.ulcerans_Agy99 GGAGGMGGSGG--WLLGNGGAGGAGGVGCAGVSGGVG----GTGGNAMLF MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GSTAVNGDVRD--SNIINADHGSNVGVDQSQTRVGGDYTNVSGHGSADID MAV_4827|M.avium_104 GGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAAANAPL Mb0896c|M.bovis_AF2122/97 YLFG------------------SGGAGGQGGMGAAG-------------- Rv0872c|M.tuberculosis_H37Rv YLFG------------------SGGAGGQGGMGAAG-------------- MMAR_2490|M.marinum_M LLFG------------------SGGAGGQGGTGVAG-------------- TH_3810|M.thermoresistible__bu GIIS--------------------LLSLAGNGGNGG-------------- Mflv_5091|M.gilvum_PYR-GCK GVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------- Mvan_1264|M.vanbaalenii_PYR-1 GVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------- MSMEG_0868|M.smegmatis_MC2_155 GGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNV MUL_0572|M.ulcerans_Agy99 GNGGAGGMGGAGADGAVGAAGTAGTSTSAGGVGGAG------------WD MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 KSVTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTN-------------T MAV_4827|M.avium_104 FASS------------------TAALAYAQDPGTGAVD------------ Mb0896c|M.bovis_AF2122/97 ADGVNPTPTGTADAGSTG-------------------------------- Rv0872c|M.tuberculosis_H37Rv ADGVNPTPTGTADAGSTG-------------------------------- MMAR_2490|M.marinum_M TNGSNPLVFDTANPGAAG-------------------------------- TH_3810|M.thermoresistible__bu -NGYRTTDNNALDGGHGG-------------------------------- Mflv_5091|M.gilvum_PYR-GCK AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------- Mvan_1264|M.vanbaalenii_PYR-1 AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------- MSMEG_0868|M.smegmatis_MC2_155 TVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDG MUL_0572|M.ulcerans_Agy99 ATAAGVLAATGGDGGDSGGGGAGGNGGAGGAGGHG--------------S MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 EIGSHNQANIGTSTSAGG-------------------------------- MAV_4827|M.avium_104 QYSLPDYLYVPVDPEPGD-------------------------------- Mb0896c|M.bovis_AF2122/97 -------------------------------------------------- Rv0872c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_2490|M.marinum_M -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------NGGNV-G Mflv_5091|M.gilvum_PYR-GCK -AVGAAGAAG------TVGTAGATGGTG---------------TGANG-G Mvan_1264|M.vanbaalenii_PYR-1 -AIGTAGVAG------AAGTAGATGGTG---------------VGGNG-G MSMEG_0868|M.smegmatis_MC2_155 HAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDG-G MUL_0572|M.ulcerans_Agy99 ALFGADGANGNGGAGGAGGNPGAPGNGG---------------TGGVGPD MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------------- MAV_4827|M.avium_104 -------------------------------------------------D Mb0896c|M.bovis_AF2122/97 --TDQTLGGN------------------AIGGNGGPGDAG---------- Rv0872c|M.tuberculosis_H37Rv --TDQTLGGN------------------AIGGNGGPGDAG---------- MMAR_2490|M.marinum_M --QDVTTTDDPAANP-------------LTGGNGSEGAAG---------- TH_3810|M.thermoresistible__bu FFSLFNLGG--------------------AGGWGGSGVDG---------- Mflv_5091|M.gilvum_PYR-GCK AGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGG Mvan_1264|M.vanbaalenii_PYR-1 AGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGG MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE MUL_0572|M.ulcerans_Agy99 AATSGGMGGTGGDPG-------------AVGGRGNSGAAGGAGAVAGASG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---SAAVGGN-------------------AGLAGNAGLAG---------- MAV_4827|M.avium_104 ELAYSAVGEE--------------------DAESPTVVIEKLFLPEDSEP Mb0896c|M.bovis_AF2122/97 ----DAMTSGGAGGSGGNAVSTVNGDAVG--------------------- Rv0872c|M.tuberculosis_H37Rv ----DAMTSGGAGGSGGNAVSTVNGDAVG--------------------- MMAR_2490|M.marinum_M ----STIQNGGVGGQGGSATSTNQNSALG--------------------- TH_3810|M.thermoresistible__bu -----------VDVVGGNP------------------------------- Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG--------- Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG--------- MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG MUL_0572|M.ulcerans_Agy99 AAGTIIAGNGGNGGAGGAGYAADGPAGPAIGNG--GDGGHG--------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ----NAGLAGNAGLAGNAGLAGNAGLAGNAG------------------- MAV_4827|M.avium_104 RRRPVLLVGSGLAVVGISAVLALEIALAIG-------------------- Mb0896c|M.bovis_AF2122/97 ----------GEGGKGGEG----------------------------AYG Rv0872c|M.tuberculosis_H37Rv ----------GEGGKGGEG----------------------------AYG MMAR_2490|M.marinum_M ----------GEGGKGGDG----------------------------ANG TH_3810|M.thermoresistible__bu -----------DGGTPG------------------------------AHG Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG MUL_0572|M.ulcerans_Agy99 ----GAGGFYGNGGAGGAGGNSAP---------------------GGGTG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --------LAGNAGLAGNAG-------------------------LAGNA MAV_4827|M.avium_104 ---------IRTTGTVALQPTPN-------------------QHLIVPTE Mb0896c|M.bovis_AF2122/97 GAGGAGGSAASIGN------------------------------------ Rv0872c|M.tuberculosis_H37Rv GAGGAGGSAASIGN------------------------------------ MMAR_2490|M.marinum_M GMGGNGGSGDTSGQTD---------------------------------- TH_3810|M.thermoresistible__bu ESHTPGVYTDRQ-------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GKGGNGGNGGRGGLFG---------------KGGNAGNGAD--------- Mvan_1264|M.vanbaalenii_PYR-1 GKGGNGGNGGRGSLFG---------------RGGNAGNGGN--------- MSMEG_0868|M.smegmatis_MC2_155 AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN MUL_0572|M.ulcerans_Agy99 GNGGTGGDSGAMGSSG--------------GRGGDGGVGTNG-------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAG---------------------------------- MAV_4827|M.avium_104 QAPAPPPVQASAPQPK---------------------------------- Mb0896c|M.bovis_AF2122/97 ----------------AAIGGNGGAGGNAQAPGGVGG------------- Rv0872c|M.tuberculosis_H37Rv ----------------AAIGGNGGAGGNAQAPGGVGG------------- MMAR_2490|M.marinum_M ------------APQPSATGGNGGNGGDAQVAGGAGG------------- TH_3810|M.thermoresistible__bu -----------------GEDGEDGTGTGIGGRGGNGG------------- Mflv_5091|M.gilvum_PYR-GCK -------------GGTGGAGGAGGTGG-TGGAGGTGG------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------GGTGGNGGNGGTGG-TGGNGGTGG------------- MSMEG_0868|M.smegmatis_MC2_155 GPAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST MUL_0572|M.ulcerans_Agy99 -----------GAGGGGGNATSYGTANATGGAGGDGG------------- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ------------NAGLAGNAGLAGNAGLAGNAGLAGN------------- MAV_4827|M.avium_104 ------------ISVPEPVAAPKPLSPPVAAPLPAAP------------- Mb0896c|M.bovis_AF2122/97 ----AGGEGGDAQVGTNSPSNAEAGNGGSGGNGFDSFASGGTGGAGGTGG Rv0872c|M.tuberculosis_H37Rv ----AGGEGGDAQVGTNSPSNAEAGNGGSGGNGFDSFASGGTGGAGGTGG MMAR_2490|M.marinum_M ----AGGWGGDGHANQ---GDAVGGVGGRGGAGFASSAAGGAGGTGGTGG TH_3810|M.thermoresistible__bu ---SSSGTHPMAEDG--------EHVKALDGRPGLD---GGNGSHGGNGG Mflv_5091|M.gilvum_PYR-GCK ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG Mvan_1264|M.vanbaalenii_PYR-1 ----TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGG MSMEG_0868|M.smegmatis_MC2_155 GQTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGG MUL_0572|M.ulcerans_Agy99 --TGSTGNGGSGGDGGN----GGTGHGGGGGPGGTAINYGAGDAFGGAAG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 --AGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAAVAGNAAVAGNAAVAGN MAV_4827|M.avium_104 ----PPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPVRIPVPDPVSPP Mb0896c|M.bovis_AF2122/97 AGGRGGLLIGDGGAG-------GAGGVGGTGGSG---------APGGGG- Rv0872c|M.tuberculosis_H37Rv AGGRGGLLIGDGGAG-------GAGGVGGTGGSG---------APGGGGG MMAR_2490|M.marinum_M QGGNGGLLFGNGGTG-------GVGGTGGMGGAG---------AAGGTG- TH_3810|M.thermoresistible__bu HGGRGGFL-GIGGSG-------GWGGHGGNGGD-----------TDADG- Mflv_5091|M.gilvum_PYR-GCK KGGTGGTG-GAGGTG----GDGGTGGTGGTGGTG---------GTGGTG- Mvan_1264|M.vanbaalenii_PYR-1 KGGTGGTG-GDGGTG----GTGGTGGTGGTGGTG---------GTGGTG- MSMEG_0868|M.smegmatis_MC2_155 RGGDGALG-GNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNG- MUL_0572|M.ulcerans_Agy99 KGGTGVVG-GNGGSG-------GAAYNYGTGNAT---------GAGGSS- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 AAVGGVLNTGVSGAIG------GSSHVGGAINES----------LGGSGS MAV_4827|M.avium_104 QLLAPPRLSVPQPVQP------PVRVPQPPSPPQ----------VGGTVP Mb0896c|M.bovis_AF2122/97 AGGDGGAAN-------------TDSAGSSR--------KAFGGDGG---- Rv0872c|M.tuberculosis_H37Rv AGGDGGAAN-------------TDSAGSSR--------KAFGGDGG---- MMAR_2490|M.marinum_M --GDGGNAG-------------FAIGGSDG--------TATGQQGG---- TH_3810|M.thermoresistible__bu --GNGGDG---------------GNGGSAG-------------------- Mflv_5091|M.gilvum_PYR-GCK --GTGGAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---- Mvan_1264|M.vanbaalenii_PYR-1 --GTGGAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---- MSMEG_0868|M.smegmatis_MC2_155 --GNGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALI MUL_0572|M.ulcerans_Agy99 --GSGGAASVPN--SASTATATSGSGGAGG----DGTDGGNGGSGG---- MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 VGGSTAVGG-------------GAHTGVGG--------GVSTGVGVG--- MAV_4827|M.avium_104 QSPPQHQTP-------------PGEGTPPK-------------------- Mb0896c|M.bovis_AF2122/97 -------------VGGDGASALGTGGEGGIG------------------- Rv0872c|M.tuberculosis_H37Rv -------------VGGDGASALGTGGEGGIG------------------- MMAR_2490|M.marinum_M -------------DGGYGADSTAVGGTGGAG------------------- TH_3810|M.thermoresistible__bu -------------RGGTGGLRGVFGINGGNG------------------- Mflv_5091|M.gilvum_PYR-GCK -------------TGGTGGQGG-LGGGGGTG------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------TGGTGGQGG-LGGVGGTG------------------- MSMEG_0868|M.smegmatis_MC2_155 RATVIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASG MUL_0572|M.ulcerans_Agy99 ----------FAFTFGTGNIIAGVGGGGGTG------------------- MLBr_01183|M.leprae_Br4923 -------------------MPLFLNAEPQAL------------------- MAB_4284c|M.abscessus_ATCC_199 -------------SHVGGGISESLGGSGSVG------------------- MAV_4827|M.avium_104 -------------PDGPGNYGGGHVPTPGAG------------------- Mb0896c|M.bovis_AF2122/97 ----GQGGNGGAGGLLIGNGGAGGVGGTA--------GAGGTGGSGGAGG Rv0872c|M.tuberculosis_H37Rv ----GQGGNGGAGGLLIGNGGAGGVGGTA--------GAGGTGGSGGAGG MMAR_2490|M.marinum_M ----GTGGNGGNGGWLIGSGGAGGVSGTG--------GVGGTGGAGGAGG TH_3810|M.thermoresistible__bu -----RAGLGGRGX-XXXGGGVGAAVRSG---------------NGVFSG Mflv_5091|M.gilvum_PYR-GCK ----GQGGTGGTGG-QGGTGGTGGTGGTG--------GTGGAGGDGGLGG Mvan_1264|M.vanbaalenii_PYR-1 ----GTGGTGGTGG-QGGTGGTGGTGGTG--------GTGGAGGDGGLGG MSMEG_0868|M.smegmatis_MC2_155 TATDGHGGSGINGG-HGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGG MUL_0572|M.ulcerans_Agy99 --STGVGGIGGSGGGADINNGAFTVVPQG--------GAGGHGGDGATDG MLBr_01183|M.leprae_Br4923 -----------TAAANTLEGLSAATVASN------------AAAAQLTTE MAB_4284c|M.abscessus_ATCC_199 -------GSTAVGGGAHTGVGGGVSTGVG---------VGSHVGGGISES MAV_4827|M.avium_104 -------GSGGSGGGHVPTPGAGGSGGSG----------GGHVPTPGTGG . Mb0896c|M.bovis_AF2122/97 AGGAGGGGTNSGPGAAFG-----GNGNTGGN------------------- Rv0872c|M.tuberculosis_H37Rv AGGAGGGGTNSGPGAAFG-----GNGNTGGN------------------- MMAR_2490|M.marinum_M IGGIGGNTSSSSTASVAGEGGHGGDGGDGGD------------------- TH_3810|M.thermoresistible__bu GGGTPSAGFGVPTTIQFPAGSCTSRAVSREG------------------- Mflv_5091|M.gilvum_PYR-GCK LGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----G Mvan_1264|M.vanbaalenii_PYR-1 LGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----G MSMEG_0868|M.smegmatis_MC2_155 LGGNGGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQ MUL_0572|M.ulcerans_Agy99 --GAGGAGGFTEIDSSASVIAATGGAGGDGG---SGGTGRGGTGGG---G MLBr_01183|M.leprae_Br4923 IAPPAADDVSILLAHFFSGHGRQYQAHASQG------------------- MAB_4284c|M.abscessus_ATCC_199 LGGSGSVGGSTAVGGGAHTGVGGGVNTGVGVG------------------ MAV_4827|M.avium_104 PGGTGGSGGGHVPTPGAGTPGGSGGG------------------------ . Mb0896c|M.bovis_AF2122/97 ------GGNGGAPGALGG---------------------------KGGSG Rv0872c|M.tuberculosis_H37Rv ------GGNGGAPGALGG---------------------------KGGSG MMAR_2490|M.marinum_M ------GGNGGAAGAVAG---------------------------AGGRG TH_3810|M.thermoresistible__bu -----IMPSSRAASARAG---------------------------AACAS Mflv_5091|M.gilvum_PYR-GCK SGSAGKAGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAA Mvan_1264|M.vanbaalenii_PYR-1 SGSAGTAGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGAS MSMEG_0868|M.smegmatis_MC2_155 SGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNT MUL_0572|M.ulcerans_Agy99 TGGGGTGGGGGVGINNGSGEAIGGAPGAGGTG------AVGGDGGQGGAA MLBr_01183|M.leprae_Br4923 --------ATNHQDLIQS--------------------------LLTSSS MAB_4284c|M.abscessus_ATCC_199 -----SHVGGGISESLGG---------------------------SGSVG MAV_4827|M.avium_104 -----HLPFPGAGSTPGG-----------------------------SGG . Mb0896c|M.bovis_AF2122/97 GLIGRAGSDGGVGAGGAGG------------------------------- Rv0872c|M.tuberculosis_H37Rv GLIGRAGSDGGVGAGGAGG------------------------------- MMAR_2490|M.marinum_M GLIGAAGGTGSIGAGGAAG------------------------------- TH_3810|M.thermoresistible__bu STSRSRRSFCCSRA------------------------------------ Mflv_5091|M.gilvum_PYR-GCK GKAGATGAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGS Mvan_1264|M.vanbaalenii_PYR-1 GAQGSAGSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGS MSMEG_0868|M.smegmatis_MC2_155 ATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGG MUL_0572|M.ulcerans_Agy99 YSYGTGDATGSAGAAGTAG-----------TTGVGGTGGAGGAAYTLNGA MLBr_01183|M.leprae_Br4923 AYAGTETANHDSL------------------------------------- MAB_4284c|M.abscessus_ATCC_199 GSTAVGGGAHTSAINDALG------------------------------- MAV_4827|M.avium_104 GHLPTPGAGTPGGGLGGFG------------------------------- . Mb0896c|M.bovis_AF2122/97 --------------------------------------------AGGAGG Rv0872c|M.tuberculosis_H37Rv --------------------------------------------AGGAGG MMAR_2490|M.marinum_M --------------------------------------------AGGAGG TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK QGAAGKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG Mvan_1264|M.vanbaalenii_PYR-1 QGAAGKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG MSMEG_0868|M.smegmatis_MC2_155 KGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGG MUL_0572|M.ulcerans_Agy99 STAT-------ATGGIG----------GNGGDGGTANGS--NGGNGGAGG MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------GSGSVGG MAV_4827|M.avium_104 ---------------------------------------------GGHAP Mb0896c|M.bovis_AF2122/97 ----------------------------------------TGGEGGTGG- Rv0872c|M.tuberculosis_H37Rv ----------------------------------------TGGEGGTGG- MMAR_2490|M.marinum_M ----------------------------------------AGGAGGAGGT TH_3810|M.thermoresistible__bu -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -----------AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGG- Mvan_1264|M.vanbaalenii_PYR-1 -----------AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGG- MSMEG_0868|M.smegmatis_MC2_155 NTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGG- MUL_0572|M.ulcerans_Agy99 -------YASTTGTGTASVGNGGRGGDGTAT-------VATGGTGGVGGN MLBr_01183|M.leprae_Br4923 -------------------------------------------------- MAB_4284c|M.abscessus_ATCC_199 ---------------STAVGGGAHTSAINESMNSSINASHSSSMNESFGS MAV_4827|M.avium_104 ---------------------------------------APGGGLGGGGG Mb0896c|M.bovis_AF2122/97 -DGKTTDGNPGMGGSPGSAGQPGQPG---------- Rv0872c|M.tuberculosis_H37Rv -DGKTTDGNPGMGGSPGSAGQPG------------- MMAR_2490|M.marinum_M AQGSGASGGTGANGHTGLDGAPGQPG---------- TH_3810|M.thermoresistible__bu ------------------------------------ Mflv_5091|M.gilvum_PYR-GCK -SGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD Mvan_1264|M.vanbaalenii_PYR-1 -SGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD- MSMEG_0868|M.smegmatis_MC2_155 -TTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP MUL_0572|M.ulcerans_Agy99 AHAPAGSPVPGVGGKGGNPGPGGKPGPNGADGIVV- MLBr_01183|M.leprae_Br4923 ------------------------------------ MAB_4284c|M.abscessus_ATCC_199 SMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH MAV_4827|M.avium_104 HAPAPGGGLGGFGGGHSGGGLGGLGGGHK-------