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SFVVVDPEMVAATAADLANIGSTIGAANGAAAATTRAVLAAGGDEISAAVAACFEAQAEAYQTFGAHTAA LHDQIVRALTAGAGGYSAVEAANTSLQQAANLVTSPVQTLTGRPLFGNGADATTPGANGGNGGWLIGSGG DGAAGGVAGQAGGSGGSAGLIGDGGNGGTGGFGAAGGTGGAGGMLFGNGGNGGAGGVGVTAGLGGNGGAG GSAGLWGHGGNGGIGGAGGAGADGVNPVPADAPFSYADSGQQGHDVIDGTAAGGHAGADGTTAGEIGGVG GRGGAAWAQSPTGTPNVTGGAGGGGGDGGSGAMGGGGGAGGDATAGTGAVATGGAGGDGGAGGAGAIGGA GGAGGSAGTVLGTGSAHGGAGGAGGAGGAGAAGGIGGAGGSADVNANVFPGQSATGGNGGMGGRGGDGVA AGLAGDGGNGGVGGRGGVLFGDGGIGGAGGGGGIGGTGAVGGGGGAGGAAGDGAFGGGPFHTGQGGVGGD GGDGGAGGDGGNGGNGGAGGAGGLIGHSGGSGLGGAAGGGGSGGAGGLGGAGGFGEGGGAAAGANGATGA TGNSGHSGQAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_3816 | - | - | 100% (572) | PE-PGRS family protein, PE_PGRS59 |
| M. marinum M | MMAR_4735 | - | e-161 | 54.66% (580) | PE-PGRS family protein |
| M. marinum M | MMAR_2490 | - | e-159 | 50.39% (637) | PE-PGRS family protein, PE_PGRS15_1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2878 | PE_PGRS48 | 1e-163 | 51.69% (621) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 1e-107 | 45.52% (558) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1243c | PE_PGRS23 | 1e-163 | 55.05% (574) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 1e-09 | 43.01% (93) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 7e-48 | 33.55% (456) | hypothetical protein MAB_4284c |
| M. avium 104 | MAV_4827 | - | 2e-22 | 41.44% (181) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-90 | 38.71% (620) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 3e-43 | 37.84% (333) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_3741 | - | 0.0 | 83.17% (416) | N-term PE-PGRS family protein |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-105 | 45.84% (541) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MMAR_3816|M.marinum_M --------------------------------------------------
MUL_3741|M.ulcerans_Agy99 --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2878|M.bovis_AF2122/97 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MMAR_3816|M.marinum_M --------------------------------------------------
MUL_3741|M.ulcerans_Agy99 --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv --------------------------------------------------
Mb2878|M.bovis_AF2122/97 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MMAR_3816|M.marinum_M ------------------------------------------MSFVVVDP
MUL_3741|M.ulcerans_Agy99 ------------------------------------------MSFVVVDP
Rv1243c|M.tuberculosis_H37Rv ------------------------------------------MEYLIAAQ
Mb2878|M.bovis_AF2122/97 ------------------------------------------MLYVVASP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------MSIIDFILNLFRDP
MAV_4827|M.avium_104 -------------------------------------MNIVLGVSMAPSS
MLBr_01556|M.leprae_Br4923 --------------------------------MAGKARVHELAKELGVTS
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MMAR_3816|M.marinum_M ----------------------------------------EMVAATAADL
MUL_3741|M.ulcerans_Agy99 ----------------------------------------EMVAATAADL
Rv1243c|M.tuberculosis_H37Rv ----------------------------------------DVLVAAAADL
Mb2878|M.bovis_AF2122/97 ----------------------------------------DLMTAAATNL
TH_3810|M.thermoresistible__bu -----------------------------------------VDGDGG---
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------VEAASYVADPEAAL
MAV_4827|M.avium_104 ---------------------------------------IQMVVLEGEYA
MLBr_01556|M.leprae_Br4923 KEVLARLN-----------------------------EQGEFVKSASSTV
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
MMAR_3816|M.marinum_M AN----------------------IGSTIG-----------AANGAAAAT
MUL_3741|M.ulcerans_Agy99 AN----------------------IGSTIG-----------AANGAAAAT
Rv1243c|M.tuberculosis_H37Rv EG----------------------IGSALA-----------AANRAAEAP
Mb2878|M.bovis_AF2122/97 AE----------------------IGSAIS-----------TANGAAALP
TH_3810|M.thermoresistible__bu ------------------------------------------SGGRTGLF
MAB_4284c|M.abscessus_ATCC_199 ANAG----------------LSAVSAAQVG---------AVMPVVAESVA
MAV_4827|M.avium_104 DG---------------------------------------ATVEEDAID
MLBr_01556|M.leprae_Br4923 EAPVAR-----------------RLRESFGG------IKPAADKGAEQVA
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
MMAR_3816|M.marinum_M TR-------AVLAAGGDEISAAVAACFEAQAEAYQTFG------------
MUL_3741|M.ulcerans_Agy99 TR-------AVLAAGGDEISAAVAACFEAQAEAYRTFG------------
Rv1243c|M.tuberculosis_H37Rv TT-------GLLAAGADEVSAAIASLFSGNAQAYQALS------------
Mb2878|M.bovis_AF2122/97 TV-------EVVAAAADEVSTQIAALFGAHARSYQTLS------------
TH_3810|M.thermoresistible__bu SK---------LSRGGDGGDGGLGGN-GGHGGGTGIIS------------
MAB_4284c|M.abscessus_ATCC_199 SNYGYQSQWVNTGNPIHDLSGNLQNYYAAQPDGPSILS---PSLLSPRDN
MAV_4827|M.avium_104 VTG---ADDAATASAPDRVISAILGTREGAADAGLQLS------------
MLBr_01556|M.leprae_Br4923 TKAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQVDHS-----AAVVP
. ..
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MMAR_3816|M.marinum_M -----AHTAALHDQIVRALTAGAGGYSAVEAANTS-----LQQAANLVTS
MUL_3741|M.ulcerans_Agy99 -----AHTAALHDQIVRALTAGAGGYSAVEAANTS-----LQQAANLVTS
Rv1243c|M.tuberculosis_H37Rv -----AQAAAFHQQFVRALSSAAGSYAAAEAANASP----MQAVLDVVNG
Mb2878|M.bovis_AF2122/97 -----TQAAAFHSRFVQALTTAAASYASVEAANASP----LQVALDVINA
TH_3810|M.thermoresistible__bu -------------LLSLAGNGGNGGNGYRTTDNNAL-----DGGHGGNGG
MAB_4284c|M.abscessus_ATCC_199 DFLSHNDTDFASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGNR
MAV_4827|M.avium_104 -----SIGVTWTDQLEAAALRDALAARRIDNVMLVS----AFLAAAALAQ
MLBr_01556|M.leprae_Br4923 IVAGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTG
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
MMAR_3816|M.marinum_M PVQTLTGRP-----LFGNGADATTPGANG--GNGG-------------WL
MUL_3741|M.ulcerans_Agy99 PVQTLTGRP-----LFGNGADATTPGANG--GNGG-------------WL
Rv1243c|M.tuberculosis_H37Rv PTQLLLGRP-----LIGDGANGG-PGQNG--GDGG-------------LL
Mb2878|M.bovis_AF2122/97 PAQTLLGRP-----LIGNGADGSTPGQAG--GPGG-------------LL
TH_3810|M.thermoresistible__bu NVGFFSLFN------LGGAGGWGGSGVDG---------------------
MAB_4284c|M.abscessus_ATCC_199 DTTAIGDGA----VAVGGSNSGPIASGQGSTAVNG------------DVR
MAV_4827|M.avium_104 NVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPD-------------VY
MLBr_01556|M.leprae_Br4923 PHPGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPP---------APRPSA
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
MMAR_3816|M.marinum_M IGSGGDGAAGGVAGQAG---------------------------------
MUL_3741|M.ulcerans_Agy99 IGSGGDGAAGGVAGQAG---------------------------------
Rv1243c|M.tuberculosis_H37Rv YGNGGNGGSSSTPGQPG---------------------------------
Mb2878|M.bovis_AF2122/97 YGNGGNGAAGG-PNQAG---------------------------------
TH_3810|M.thermoresistible__bu VDVVGGNPDGGTPGAHG---------------------------------
MAB_4284c|M.abscessus_ATCC_199 DSNIINADHGSNVGVDQ---------------------------------
MAV_4827|M.avium_104 KQQIRAESYGDAAGQLS---------------------------------
MLBr_01556|M.leprae_Br4923 SPSSMSPRPGGAVGGGGP------------------------------RP
.. .
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTGANGGAGGVG-----GVGGTGAAGAAGGAGGLG
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVGGNGGAGQAG-----GIGGTGAAGAAGQAGTAG
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
MMAR_3816|M.marinum_M ------GSGGSAGLIGDGGNGGTGGFG-----------------------
MUL_3741|M.ulcerans_Agy99 ------GNGGSAGLIGDGGNGGTGGFG-----------------------
Rv1243c|M.tuberculosis_H37Rv ------GRGGAAGLIGNGGAGGAGGPG-----------------------
Mb2878|M.bovis_AF2122/97 ------GAGGNAGLIGNGGAGGAGGVG-----------------------
TH_3810|M.thermoresistible__bu ------ESHTPGVYTDRQGEDGEDGTG-----------------------
MAB_4284c|M.abscessus_ATCC_199 -----SQTRVGGDYTNVSGHGSADIDKSVTVVDDHSQRNTTNINDSFNTD
MAV_4827|M.avium_104 -----AMVAGLEKLESLPGGLLLVGSG----VDVAPLKQVLQTTTFLDVS
MLBr_01556|M.leprae_Br4923 PRTGVPRPGGGRPGAPVGGRSDAGGGN-----YRGGGVGALPGGGSGGFR
.
Mflv_5091|M.gilvum_PYR-GCK ETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGAG
Mvan_1264|M.vanbaalenii_PYR-1 ETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGVG
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
MMAR_3816|M.marinum_M ---AAGGTGGAG----------------------GMLFGNGGNGGAGGVG
MUL_3741|M.ulcerans_Agy99 ---AAGGTGGAG----------------------GMLFGNGG---AGGVG
Rv1243c|M.tuberculosis_H37Rv ---ANGGAGGNG----------------------GWLYGNGGLGGNGGAA
Mb2878|M.bovis_AF2122/97 ---AVGGNGGTG----------------------GLLFGNGGAGGQGGLG
TH_3810|M.thermoresistible__bu --TGIGGRGGNG----------------------GSSSGTHPMAEDGEHV
MAB_4284c|M.abscessus_ATCC_199 RSTNIGSGNTTN-----------------------TEIGSHNQANIGTST
MAV_4827|M.avium_104 VAEEPETALARG---------------------AALAAANAPLFASSTAA
MLBr_01556|M.leprae_Br4923 GRPGGGGHGGGG--------------------RPGQRGGAAGAFGRPGGA
. .
Mflv_5091|M.gilvum_PYR-GCK ----------STGAVGG-------VGGKG----IQGGQG-----------
Mvan_1264|M.vanbaalenii_PYR-1 ----------ATGGAGG-------VGGKG----IQGGQG-----------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
MMAR_3816|M.marinum_M V-------------------------------------------------
MUL_3741|M.ulcerans_Agy99 V-------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv T-------------------------------------------------
Mb2878|M.bovis_AF2122/97 LA------------------------------------------------
TH_3810|M.thermoresistible__bu K-------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 S-------------------------------------------------
MAV_4827|M.avium_104 LAY-----------------------------------------------
MLBr_01556|M.leprae_Br4923 PRRGRKSKRQKRQEYDS---------------------------------
Mflv_5091|M.gilvum_PYR-GCK --LQGGKGGDGGAGGKGGDADSMGS------------------AGATGGK
Mvan_1264|M.vanbaalenii_PYR-1 --LQGGQGGDGGTGGTGGDATSMGE------------------AGATGGK
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
MMAR_3816|M.marinum_M ---------------------------------------------TAG-L
MUL_3741|M.ulcerans_Agy99 ---------------------------------------------TAG-L
Rv1243c|M.tuberculosis_H37Rv ---------------------------------------------QIGGN
Mb2878|M.bovis_AF2122/97 --------------------------------------------GINGGS
TH_3810|M.thermoresistible__bu --------------------------------------------ALDGRP
MAB_4284c|M.abscessus_ATCC_199 -------------------------------------------AGGSAAV
MAV_4827|M.avium_104 --------------------------------------------AQDPGT
MLBr_01556|M.leprae_Br4923 -----------------------------------------MQAPVVGGV
Mflv_5091|M.gilvum_PYR-GCK GGNGGNGGRGGLFG---------------KGGNAGNGAD-----------
Mvan_1264|M.vanbaalenii_PYR-1 GGNGGNGGRGSLFG---------------RGGNAGNGGN-----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
MMAR_3816|M.marinum_M GGNGGAGGSAGLWG------------------HGGNGGI-----------
MUL_3741|M.ulcerans_Agy99 GGNGGAGGSVGLWG------------------HGGNGGI-----------
Rv1243c|M.tuberculosis_H37Rv GGNGGHGGNAGLWG------------------NGGAGGA-----------
Mb2878|M.bovis_AF2122/97 GGQGGHGGNAILFG------------------QGGAGGP-----------
TH_3810|M.thermoresistible__bu GLDGGNGS------------------------HGGNGGH-----------
MAB_4284c|M.abscessus_ATCC_199 GGNAGLAGNAGLAG------------------NAGLAGN-----------
MAV_4827|M.avium_104 GAVDQYSLPDYLYVP----------------VDPEPGDD-----------
MLBr_01556|M.leprae_Br4923 RLPHGNGETIRLARG-------ASLSDFAEKIDANPAALVQALFNLG---
. .
Mflv_5091|M.gilvum_PYR-GCK -----------GGTGGAGGAGGTGG-TGGAGGTGG---------------
Mvan_1264|M.vanbaalenii_PYR-1 -----------GGTGGNGGNGGTGG-TGGNGGTGG---------------
MSMEG_0868|M.smegmatis_MC2_155 AGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTGQ
MMAR_3816|M.marinum_M ------------GGAGGAGADGVNPVPADAPFSYAD--------------
MUL_3741|M.ulcerans_Agy99 ------------GGAGGAGADGVNPLPADAPFSHAD--------------
Rv1243c|M.tuberculosis_H37Rv ------------GAAGAAGANGQN--PVSHQVTHAT--------------
Mb2878|M.bovis_AF2122/97 ------------GGTGAMGVAGTNPTPIGTAAPGSDGVNQIGNGGNTDLT
TH_3810|M.thermoresistible__bu --------------GGRGGFLGIGG-------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------AGLAGNAGLAGNAGLAGNAGLAGNAG-------------
MAV_4827|M.avium_104 -----------ELAYSAVGEEDAESPTVVIEKLFLP--------------
MLBr_01556|M.leprae_Br4923 -------EMVTATQSVGDETLELLGSEMNYNVQVVSPEDEDRELLEPFDL
Mflv_5091|M.gilvum_PYR-GCK --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
Mvan_1264|M.vanbaalenii_PYR-1 --TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGKG
MSMEG_0868|M.smegmatis_MC2_155 TDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGRG
MMAR_3816|M.marinum_M -----SGQQG-------HDVIDGTAAGGHAGADGTTAGEIGGVGGRGGAA
MUL_3741|M.ulcerans_Agy99 -----SGQQG-------HDVIDGTAAGGHAGADGTTAGEIGGVGGRGGGA
Rv1243c|M.tuberculosis_H37Rv -----DGADG-------TTGPDGNGTDAGSGSNAVNPGVGGGAGGIGG--
Mb2878|M.bovis_AF2122/97 GGAGGDGNAG-------STTVNGGNGGTGGAARNSSGGTGNSFGGAGGAG
TH_3810|M.thermoresistible__bu --------------------SGGWGGHGGNGGDTDADGGNGGDGGNGGSA
MAB_4284c|M.abscessus_ATCC_199 --LAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAG
MAV_4827|M.avium_104 -------EDSEPRRRPVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVA
MLBr_01556|M.leprae_Br4923 TYGEDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGIT
* *
Mflv_5091|M.gilvum_PYR-GCK GTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 GDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGG
MMAR_3816|M.marinum_M WAQSPTG-------------TPNVTG--------------GAGGGGGDGG
MUL_3741|M.ulcerans_Agy99 WAQSPTG-------------TPNVTG--------------GAGG------
Rv1243c|M.tuberculosis_H37Rv -DGTNLG-------------QTDVSG--------------GAGGDGGDGA
Mb2878|M.bovis_AF2122/97 GDGANGGDGGAGGEALTEGGATAVSG--------------AGGKGGNAEA
TH_3810|M.thermoresistible__bu GRGGTGG-------------LRGVFG------------------------
MAB_4284c|M.abscessus_ATCC_199 LAGNAGLAGNAG-----LAGNAGLAG--------------NAGLAGNAGL
MAV_4827|M.avium_104 LQPTPNQHLIVP-----TEQAPAPPP-------------VQASAPQPKIS
MLBr_01556|M.leprae_Br4923 QHIGAYQVGVDLDGSERLITFIDTPGHEAFTAMR------ARGAKATDIA
Mflv_5091|M.gilvum_PYR-GCK AG-----------DGTGGTGGTGG----TGGQGGQGGQGG----------
Mvan_1264|M.vanbaalenii_PYR-1 AG-----------DGLGGTGGTGG----TGGFGGQGGQGG----------
MSMEG_0868|M.smegmatis_MC2_155 AGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVIG
MMAR_3816|M.marinum_M SG------------AMGGGGGAGG--------DATAGTGA----------
MUL_3741|M.ulcerans_Agy99 --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv NF------------ASGGAGGNGG--------AAQSGFG-----------
Mb2878|M.bovis_AF2122/97 SG------------GAGGNGGKGG--------FAQATTS-----------
TH_3810|M.thermoresistible__bu --------------INGGNGRAG---------------------------
MAB_4284c|M.abscessus_ATCC_199 AG----------NAAVAGNAAVAG--------------------------
MAV_4827|M.avium_104 VP-----------EPVAAPKPLSP--------------------------
MLBr_01556|M.leprae_Br4923 ILVVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADP--------
Mflv_5091|M.gilvum_PYR-GCK -------TGGTGGQGG-LGGGGGTG-----------------------GQ
Mvan_1264|M.vanbaalenii_PYR-1 -------TGGTGGQGG-LGGVGGTG-----------------------GT
MSMEG_0868|M.smegmatis_MC2_155 SNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDGH
MMAR_3816|M.marinum_M -----VATGGAGGDGGA---------------------------------
MUL_3741|M.ulcerans_Agy99 --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv -----DAVGGNGGAGGN---------------------------------
Mb2878|M.bovis_AF2122/97 ------VTGGNGGNGGNGHDS--------------------------NAP
TH_3810|M.thermoresistible__bu -------LGGRGX-------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----NAAVAGNAAVGG---------------------------------V
MAV_4827|M.avium_104 ------PVAAPLPAAP---------------------------------P
MLBr_01556|M.leprae_Br4923 -----AKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTA
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGS
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGGV
MSMEG_0868|M.smegmatis_MC2_155 GGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGGD
MMAR_3816|M.marinum_M GGAGAIGGAGGAGGSAGTVLGT------GSAHGGAGGAGGAGGAGAAGGI
MUL_3741|M.ulcerans_Agy99 --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv GGAGGGGGLGGAGGSAN-VANA------GNSIGGNGGAGGNGGIGAPGGA
Mb2878|M.bovis_AF2122/97 GGAGGSGGVGGDGGRGG-LLAG------NGGTGGAGGNGGTGGAGAPGGA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 LNTGVSGAIGGSSHVGGAINES------------LGGSGSVGGSTAVGGG
MAV_4827|M.avium_104 PAAPPLPEAPPIPAAPPVVPVP------VVVPPVPVPVPVRIPVPDPVSP
MLBr_01556|M.leprae_Br4923 DAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGD
Mflv_5091|M.gilvum_PYR-GCK GGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG-----GSGSAGK
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG-----GSGSAGT
MSMEG_0868|M.smegmatis_MC2_155 GVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGP-SWVQSGYGST
MMAR_3816|M.marinum_M GGAGGSADVNANVFPGQSATGGNG----GMGGRGGDGV--AAGLAGDGGN
MUL_3741|M.ulcerans_Agy99 --------------------------------------------------
Rv1243c|M.tuberculosis_H37Rv GGAGG--NANQDNPPGGNSTGGNG----GAGGDGGVGA--SADVGGAGGF
Mb2878|M.bovis_AF2122/97 GGAGGKADIANSLGDNATVTGGNG----GTGGDGGSALG-TGGAGGAGGL
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGGSTAVGGGAHTGVGGG
MAV_4827|M.avium_104 PQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSPPQHQTPPGEGTP
MLBr_01556|M.leprae_Br4923 AYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIAR
Mflv_5091|M.gilvum_PYR-GCK AGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGAT
Mvan_1264|M.vanbaalenii_PYR-1 AGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSA
MSMEG_0868|M.smegmatis_MC2_155 LGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDG
MMAR_3816|M.marinum_M GGVGGRGGVLFGDGGIGGAGGGGGIG-------------GTGAVGGGGGA
MUL_3741|M.ulcerans_Agy99 -------------------------------------------------A
Rv1243c|M.tuberculosis_H37Rv GGSGGRGGLLLGTGG---AGGDGGVG-------------GDGGIGAQGGS
Mb2878|M.bovis_AF2122/97 GGHGGAGGLLIGNGGAGGAGGLGGAG-------------GAGGAGGEGGA
TH_3810|M.thermoresistible__bu ----------------------------------------------XXXG
MAB_4284c|M.abscessus_ATCC_199 VSTGVGVGSHVGGGISESLGGSGSVG-------------GSTAVGGGAHT
MAV_4827|M.avium_104 PKPDGPGNYGGGHVPTPGAGGSGGSG-----------GGHVPTPGAGGSG
MLBr_01556|M.leprae_Br4923 QIADRRSARKRNALAARSRKRISLEDLDS-------ALKETSQLNLILKG
Mflv_5091|M.gilvum_PYR-GCK GAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
Mvan_1264|M.vanbaalenii_PYR-1 GSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
MSMEG_0868|M.smegmatis_MC2_155 GAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGW
MMAR_3816|M.marinum_M GGAAGDGAFGGG----------------PFHTGQGGV--GGDGGDGGA--
MUL_3741|M.ulcerans_Agy99 GGAAGDGAFGGG----------------PYHTGQGGV--GGDG-------
Rv1243c|M.tuberculosis_H37Rv GGNGGNGGIGADG--------------MANQDGDGGD--GGNGGDGGA--
Mb2878|M.bovis_AF2122/97 GGAGGEAIPGGAS--------------TNSAGGDGGA--GGTGGNGGD--
TH_3810|M.thermoresistible__bu GGVGAAVRSGNG-----------------VFSGGGGT-------------
MAB_4284c|M.abscessus_ATCC_199 GVGGGVNTGVGVG---------------SHVGGGISESLGGSGSVGGS--
MAV_4827|M.avium_104 GSGGGHVPTPGTG----------------GPGGTGGSGGGHVPTPGAG--
MLBr_01556|M.leprae_Br4923 DNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIII
. *
Mflv_5091|M.gilvum_PYR-GCK AGATGTTGATG--------------------AAGEDGDAGSGGSG-INGG
Mvan_1264|M.vanbaalenii_PYR-1 AGATGTTGATG--------------------AAGDAGDPGSEAVD-INGG
MSMEG_0868|M.smegmatis_MC2_155 VQAYDPAGPVGSKIANS------------SAVAGNGGDGGVNGTGGASGG
MMAR_3816|M.marinum_M --------------------------------GGDGGNGGN-------GG
MUL_3741|M.ulcerans_Agy99 ------------------------------------GNGGN-------GG
Rv1243c|M.tuberculosis_H37Rv --------------------------------GGAGGVGGN-------GG
Mb2878|M.bovis_AF2122/97 --------------------------------GGAGGAPGL-------GG
TH_3810|M.thermoresistible__bu -------------------------------------------------P
MAB_4284c|M.abscessus_ATCC_199 --------------------------------TAVGGGAHTSAINDALGG
MAV_4827|M.avium_104 --------------------------------TPGGSGGGHLPFPGAGST
MLBr_01556|M.leprae_Br4923 GFNVRAEGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQ
Mflv_5091|M.gilvum_PYR-GCK AGGAGG-----------AGGEGGEGGDGGKGGAGAE--------GGAGGG
Mvan_1264|M.vanbaalenii_PYR-1 AGGAGG-----------AGGEGGEGGAGGAGGDGSE--------GGAGGS
MSMEG_0868|M.smegmatis_MC2_155 DGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGN
MMAR_3816|M.marinum_M AGGAGG-----------LIGHSGGSGLGGAAGGGGS--------GGAGGL
MUL_3741|M.ulcerans_Agy99 AGGAGG-----------LIGHSGGSGLGGAAGGGGS--------GGAGGL
Rv1243c|M.tuberculosis_H37Rv TGGAGG-----------LFGQSGSPGSGAAGGLGGA--------GGNGGA
Mb2878|M.bovis_AF2122/97 AGGAGGW----------LIGQSGSTGGGGAGGAGGA--------GGAGGA
TH_3810|M.thermoresistible__bu SAGFGVP-----------TTIQFPAGSCTSRAVSRE---------GIMPS
MAB_4284c|M.abscessus_ATCC_199 SGSVGGSTAVGGGAHTSAINESMNSSINASHSSSMN-------ESFGSSM
MAV_4827|M.avium_104 PGGSGG-------------GHLPTPGAGTPGGGLGG-------FGGGHAP
MLBr_01556|M.leprae_Br4923 LGRAEIRALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDN---IVVTDNL
. . .
Mflv_5091|M.gilvum_PYR-GCK GGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD-------
Mvan_1264|M.vanbaalenii_PYR-1 GGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD--------
MSMEG_0868|M.smegmatis_MC2_155 GGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP-------
MMAR_3816|M.marinum_M GGAGGFGEGGGAAAGANGATGATGNSGHSGQAG--------------
MUL_3741|M.ulcerans_Agy99 GGAGGFGEGGGAAAGANGATGATGNSGHSGQAG--------------
Rv1243c|M.tuberculosis_H37Rv GGGGGTGFNPGAPGDP-GTQGATGANGQHGLNG--------------
Mb2878|M.bovis_AF2122/97 GGSGGAGGHGDTTSGKNGSSGTAGFDGNPGQPG--------------
TH_3810|M.thermoresistible__bu SRAASARAGAACASSTSRSRRSFCCSRA-------------------
MAB_4284c|M.abscessus_ATCC_199 GSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH-------------
MAV_4827|M.avium_104 APGGGLGGGGGHAPAPGGGLGGFGGGHSGGGLGGLGGGHK-------
MLBr_01556|M.leprae_Br4923 TVTSLRREKDDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA
.