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SSDTGEPGGQDDQGGAGGRGGAGGRGGDGGPGGAPGIGGRPGEGGPGGAGGEPGPGGTSGQPGQPGQPGQ PGQPGAPGH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2957 | - | - | 100% (80) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_2853 | - | 5e-16 | 53.42% (73) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_4367 | - | 2e-15 | 53.95% (76) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1275c | PE_PGRS23 | 6e-18 | 54.55% (77) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 5e-18 | 56.58% (76) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3595c | PE_PGRS59 | 8e-19 | 53.33% (90) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01556 | infB | 1e-09 | 47.30% (74) | translation initiation factor IF-2 |
| M. abscessus ATCC 19977 | MAB_0321c | - | 4e-11 | 35.96% (114) | hypothetical protein MAB_0321c |
| M. marinum M | MMAR_2795 | - | 4e-38 | 70.19% (104) | PE-PGRS family protein |
| M. avium 104 | MAV_2780 | - | 4e-12 | 55.38% (65) | hypothetical protein MAV_2780 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 6e-14 | 50.68% (73) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 4e-12 | 46.15% (78) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 4e-18 | 57.33% (75) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
Mb1275c|M.bovis_AF2122/97 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
Mb1275c|M.bovis_AF2122/97 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
Mb1275c|M.bovis_AF2122/97 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 --------------------------------------------------
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
Mb1275c|M.bovis_AF2122/97 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 -------------------------------------MAGKARVHELAKE
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
Mb1275c|M.bovis_AF2122/97 --------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 LGVTSKEVLARLNEQGEFVKSASSTVEAPVARRLRESFGGIKPAADKGAE
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGG
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGLGS
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGWAG
Mb1275c|M.bovis_AF2122/97 ---------MEYLIAAQDVLVAAAADLEGIGSALAAANRAAEAPTTGLLA
Rv3595c|M.tuberculosis_H37Rv ---------MSFVIAVPEFLSAAATDLANLGSTISAANAAASIPTTGVLA
TH_3810|M.thermoresistible__bu --------------------VDGDGGSGGRTGLFSKLSRGGDGGDGGLGG
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 QVATKAQAKRLGESLDQTLDRALDKAVAGNGATTAAPVQVDHSAAVVPIV
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGATG
MSMEG_0868|M.smegmatis_MC2_155 LDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
Mb1275c|M.bovis_AF2122/97 AGADEVSAAIASLFSGNAQAYQALSAQAAAFHQQFVRALSSAAGSYAAAE
Rv3595c|M.tuberculosis_H37Rv AGADDVSAAIAALFGAHAQAYQTISAQAATFHAQFVQTLSAGAGAYANAE
TH_3810|M.thermoresistible__bu NGGHGGGTGIISLLSLAGNGGNGGNGYRTTDNNALDGGHGGNGGNVGFFS
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 AGEGPSTAHREELAPPAGQPSEQPGVPLPGQQGTPAAPHPGHPGMPTGPH
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
Mb1275c|M.bovis_AF2122/97 AANASPMQAVLDVVNGPTQLLLGRP------------------------L
Rv3595c|M.tuberculosis_H37Rv AANVQ--QSLLNAINAPTQALLGRP------------------------L
TH_3810|M.thermoresistible__bu LFNLGG--------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 PGPAPKPGGRPPRVGNNPFSSAQSVARPIPRPPAPRP------------S
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG----AVGAAG------
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG----AIGTAG------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
Mb1275c|M.bovis_AF2122/97 IGDGANG-GPGQNGGDGGLLYGNGGNGGSSSTPG----------------
Rv3595c|M.tuberculosis_H37Rv IGDGADGTAPGQNGGAGGLLYGNGGNGAAGVNAG----------------
TH_3810|M.thermoresistible__bu AGGWGGSGVDGVDVVGGNPDGGTPGAHGESHTPG----------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 ASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRPGAPVGGRSDAGGGNYR
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 ----------MANIISNG-PDGDAGATG----------------------
Mflv_5091|M.gilvum_PYR-GCK -AAGTVGTAGATGGTGTG-ANGGAGGVG-----GVGGTGAAGAAGGAGGL
Mvan_1264|M.vanbaalenii_PYR-1 -VAGAAGTAGATGGTGVG-GNGGAGQAG-----GIGGTGAAGAAGQAGTA
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAG-GNGGTGGTGRVIAEGTGSTAEGTATGGDGGH
Mb1275c|M.bovis_AF2122/97 ---QPGGRGGAAGLIGNG-GAGGAGGPG--------------ANGGAGGN
Rv3595c|M.tuberculosis_H37Rv ---IAGGSGGAAGLIGNG-GSGGAGGAG--------------AAGGSGGQ
TH_3810|M.thermoresistible__bu ---VYTDRQGEDGEDGTGTGIGGRGGNG----------------------
MAV_2780|M.avium_104 -----MFGGAAMLVLAVGCGGGHKGGPS----------------------
MLBr_01556|M.leprae_Br4923 GGGVGALPGGGSGGFRGRPGGGGHGGGGRPGQRGGAAGAFGRPGGAPRRG
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 ---------------------------------AQGSQGATGAAGAMANC
Mflv_5091|M.gilvum_PYR-GCK GETGTTGGAGGVG--------------------GQGTAGGTGGVGGIGGA
Mvan_1264|M.vanbaalenii_PYR-1 GETGVTGGVGGIG--------------------GQGTEGGTGGVGGVGGV
MSMEG_0868|M.smegmatis_MC2_155 STGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEI
Mb1275c|M.bovis_AF2122/97 G----------------------------------GWLYGNGGLGGNGGA
Rv3595c|M.tuberculosis_H37Rv G----------------------------------GLLYGNGGAGGNGGA
TH_3810|M.thermoresistible__bu -----------------------------------GSSSGTHPMAEDGEH
MAV_2780|M.avium_104 -----------------------------------TTSTTTPTTTPSTSV
MLBr_01556|M.leprae_Br4923 RKSKRQKRQEYDS-------------------MQAPVVGGVRLPHGNGET
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 N-------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK G----------STGAVGG-------VGGKG----IQGGQG----------
Mvan_1264|M.vanbaalenii_PYR-1 G----------ATGGAGG-------VGGKG----IQGGQG----------
MSMEG_0868|M.smegmatis_MC2_155 YSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGT
Mb1275c|M.bovis_AF2122/97 AT------------------------------------------------
Rv3595c|M.tuberculosis_H37Rv AT------------------------------------------------
TH_3810|M.thermoresistible__bu VK------------------------------------------------
MAV_2780|M.avium_104 VP------------------------------------------------
MLBr_01556|M.leprae_Br4923 IRLARG------------------------------------------AS
MUL_2957|M.ulcerans_Agy99 -------MSSDTGEPG----------------------------------
MMAR_2795|M.marinum_M -------MNSDTGEPG----------------------------------
MAB_0321c|M.abscessus_ATCC_199 ------WIDDDCATRG----------------------------------
Mflv_5091|M.gilvum_PYR-GCK ---LQGGKGGDGGAGGKGGDADSMGS------------------AGATGG
Mvan_1264|M.vanbaalenii_PYR-1 ---LQGGQGGDGGTGGTGGDATSMGE------------------AGATGG
MSMEG_0868|M.smegmatis_MC2_155 AKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGA
Mb1275c|M.bovis_AF2122/97 ------QIGGNGGNGGHG--------------------------------
Rv3595c|M.tuberculosis_H37Rv ------IPGGNGGAGGAG--------------------------------
TH_3810|M.thermoresistible__bu ------ALDGRPGLDG----------------------------------
MAV_2780|M.avium_104 --------STTPGGGGT---------------------------------
MLBr_01556|M.leprae_Br4923 LSDFAEKIDANPAALVQALFNLG---------------------------
.
MUL_2957|M.ulcerans_Agy99 --------------------------------GQDDQGGA----------
MMAR_2795|M.marinum_M --------------------------------GQGGQGGA----------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------GTGGTGGN----------
Mflv_5091|M.gilvum_PYR-GCK KGGNGGNGGRGGLFG---------------KGGNAGNGAD----------
Mvan_1264|M.vanbaalenii_PYR-1 KGGNGGNGGRGSLFG---------------RGGNAGNGGN----------
MSMEG_0868|M.smegmatis_MC2_155 VGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNG
Mb1275c|M.bovis_AF2122/97 --------------------------------GNAGLWGN----------
Rv3595c|M.tuberculosis_H37Rv --------------------------------GNAWLFGN----------
TH_3810|M.thermoresistible__bu --------------------------------GNGSHGGN----------
MAV_2780|M.avium_104 --------------------------------VPGGPTGG----------
MLBr_01556|M.leprae_Br4923 ----------------------------EMVTATQSVGDET---------
MUL_2957|M.ulcerans_Agy99 ------------GGRGGAG-------------------------------
MMAR_2795|M.marinum_M ------------GGRGGAGGAGGRG-------------------------
MAB_0321c|M.abscessus_ATCC_199 ------------GGPGGAGGPGGHGGVIDFEVETFMDG------------
Mflv_5091|M.gilvum_PYR-GCK ------------GGTGGAGGAGGTGG-TGGAGGTGG--------------
Mvan_1264|M.vanbaalenii_PYR-1 ------------GGTGGNGGNGGTGG-TGGNGGTGG--------------
MSMEG_0868|M.smegmatis_MC2_155 PAGTTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHSTG
Mb1275c|M.bovis_AF2122/97 ------------GGAGGAGAAGAAGANGQNPVSHQV--------------
Rv3595c|M.tuberculosis_H37Rv ------------GGAGGLGAAGAAGAAGVNPLT-----------------
TH_3810|M.thermoresistible__bu ------------GGHGGRGGFLGIGG------------------------
MAV_2780|M.avium_104 ------------GGPGGGGGSIPGGP------------------------
MLBr_01556|M.leprae_Br4923 --------LELLGSEMNYNVQVVSPEDEDRELLEPFDLTYG---------
*. . .
MUL_2957|M.ulcerans_Agy99 --------------------------GRGGDGG-------PGGAPGIGGR
MMAR_2795|M.marinum_M --------GAGGRGGAGGAGGPGGQGGRGGDGG-------PGGAPGIGGR
MAB_0321c|M.abscessus_ATCC_199 -VTLQAKGGRGGNGGHGGAGGTGGTGGKGGDGDDC-EFGRTGGNGGTGGR
Mflv_5091|M.gilvum_PYR-GCK ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
Mvan_1264|M.vanbaalenii_PYR-1 ---TGGTGGIGGAGSTGGTGGTGGTGGTGGTGGTG-GTGGTGGTGGTGGK
MSMEG_0868|M.smegmatis_MC2_155 QTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDGGR
Mb1275c|M.bovis_AF2122/97 ------THATDGADGTTGPDGNGTDAGSGSNAVNPGVGGGAGGIGGDGTN
Rv3595c|M.tuberculosis_H37Rv -----------------------VPAGQGSMGNN----GEPGGPGQPGTE
TH_3810|M.thermoresistible__bu ------------------SGGWGGHGGNGGDTDADGGNGGDGGNGGSAGR
MAV_2780|M.avium_104 ----------------------TGGGGPGGGGGS-----IPGGPTGGGGP
MLBr_01556|M.leprae_Br4923 -EDQGDEDELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQH
.
MUL_2957|M.ulcerans_Agy99 PGEG-------------------------------------------GPG
MMAR_2795|M.marinum_M PGEG-------------------------------------------GPG
MAB_0321c|M.abscessus_ATCC_199 GGDGNFAGTGGNGGAILVKCQHDLSLGTHPMD---------VSAGTGGNG
Mflv_5091|M.gilvum_PYR-GCK GGTGGTGGAGGTG----GDGGTGGTGGTGGTG---------GTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGTGGDGGTG----GTGGTGGTGGTGGTG---------GTGGTGGTG
MSMEG_0868|M.smegmatis_MC2_155 GGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNG
Mb1275c|M.bovis_AF2122/97 LGQTDVSGGAGGDGGDGANFASGGAGGNGGAAQSGFGDAVGGNGGAGGNG
Rv3595c|M.tuberculosis_H37Rv FGQT---------------------------------------GGTGGTG
TH_3810|M.thermoresistible__bu GGTGGLRG---------------------------------VFGINGGNG
MAV_2780|M.avium_104 GGGG---------------------------------------GSIPGVG
MLBr_01556|M.leprae_Br4923 IGAYQVGVDLDGSERLITFIDTPGHEAFTAMRARGAKATDIAILVVAADD
* . .
MUL_2957|M.ulcerans_Agy99 GAG---------------------------------GEPGP---------
MMAR_2795|M.marinum_M GAG---------------------------------GEPGP---------
MAB_0321c|M.abscessus_ATCC_199 GIG---------------------------------GGGGG---------
Mflv_5091|M.gilvum_PYR-GCK GAG-----------DGTGGTGGTGG----TGGQGGQGGQGG---------
Mvan_1264|M.vanbaalenii_PYR-1 GAG-----------DGLGGTGGTGG----TGGFGGQGGQGG---------
MSMEG_0868|M.smegmatis_MC2_155 GAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRATVI
Mb1275c|M.bovis_AF2122/97 GAGG------------GGGLGGAGGSANVANAGNSIGGNGG---------
Rv3595c|M.tuberculosis_H37Rv GTG------------------------------LSVGGTGG---------
TH_3810|M.thermoresistible__bu RAG--------------------------------LGGRGX---------
MAV_2780|M.avium_104 GGG---------------------------------GGPGG---------
MLBr_01556|M.leprae_Br4923 GVMP---------QTVEAINHAQAADVPIVVAVNKIDKEGADP-------
. *
MUL_2957|M.ulcerans_Agy99 ---------GGTSGQ-----------------------------------
MMAR_2795|M.marinum_M ---------GGT--------------------------------------
MAB_0321c|M.abscessus_ATCC_199 ---------GGSVGANGATTGVFSSS----------------------SD
Mflv_5091|M.gilvum_PYR-GCK --------TGGTGGQGG-LGGGGGTG-----------------------G
Mvan_1264|M.vanbaalenii_PYR-1 --------TGGTGGQGG-LGGVGGTG-----------------------G
MSMEG_0868|M.smegmatis_MC2_155 GSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTATDG
Mb1275c|M.bovis_AF2122/97 --------AGGNGGIGAPGGAGGAGG---------------NANQDNPPG
Rv3595c|M.tuberculosis_H37Rv --------TGG---------------------------------------
TH_3810|M.thermoresistible__bu --------XXXGGGVGAAVR------------------------------
MAV_2780|M.avium_104 ---------GG---------------------------------------
MLBr_01556|M.leprae_Br4923 ------AKIRGQLTEYGLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLT
MUL_2957|M.ulcerans_Agy99 ---PGQPGQPGQPGQPGA--------------------------------
MMAR_2795|M.marinum_M ---PGQPGQPGQPGQPGS--------------------------------
MAB_0321c|M.abscessus_ATCC_199 CSGPGPQPNPGSPGDPGTSVAVS---------------------------
Mflv_5091|M.gilvum_PYR-GCK QGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGQGGTGGTGGTGGTG--------GTGGAGGDGGLGGLGGFGG
MSMEG_0868|M.smegmatis_MC2_155 HGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGNGG
Mb1275c|M.bovis_AF2122/97 GNSTGGNGGAGGDGGVGASADVG---------------------------
Rv3595c|M.tuberculosis_H37Rv ---TGGTGGAGG--------------------------------------
TH_3810|M.thermoresistible__bu -SGNGVFSGGGGTPSAGFGVPTT---------------------------
MAV_2780|M.avium_104 ----GCVGNVCGAYP-----------------------------------
MLBr_01556|M.leprae_Br4923 ADAALDLRANSGMEAQGVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAG
MUL_2957|M.ulcerans_Agy99 ------------PGH-----------------------------------
MMAR_2795|M.marinum_M ------------PGH-----------------------------------
MAB_0321c|M.abscessus_ATCC_199 -------GAQGNPGQAQFLIVP----------------------------
Mflv_5091|M.gilvum_PYR-GCK SGGTGGQGGLGGPGGSTGGAGGAGG--QAGTAGKGGLFG----GSGSAGK
Mvan_1264|M.vanbaalenii_PYR-1 VGGTGGQGGQGGPGGSTGGAGGAGG--QAGVAGKGGLFG----GSGSAGT
MSMEG_0868|M.smegmatis_MC2_155 DGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYGST
Mb1275c|M.bovis_AF2122/97 -----GAGGFGGSGGRGGLLLGTGG-------------------------
Rv3595c|M.tuberculosis_H37Rv ------------SGGRGGLLVGDGG-------------------------
TH_3810|M.thermoresistible__bu --------IQFPAGSCTSRAVSREG------------------------I
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 DAYGRVRRMVDEHGVDIEAALPSSPVQVIGFTSVPGAGDNFLVVDEDRIA
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGATGAAGASGGKGAQGATGAQGATG------AQGATG-ATGAAGKAGAT
Mvan_1264|M.vanbaalenii_PYR-1 AGVTGASGASGGKGAQGATGAQGATG------AQGATG-ATGASGAQGSA
MSMEG_0868|M.smegmatis_MC2_155 LGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGGDG
Mb1275c|M.bovis_AF2122/97 AGGDGGVGGDGGIGAQGGSGGN-------------------GGNGGIGAD
Rv3595c|M.tuberculosis_H37Rv AGGIGGTGGEGGIGARGGTGGQ-------------------GGMGGAGQP
TH_3810|M.thermoresistible__bu MPSSRAASARAGAACASSTSRS---------------------RRSFCCS
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 RQIADRRSARKRNALAARSRKRISLEDLDSALKETSQLNLILKGDNAGTV
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GAAGAAGAAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
Mvan_1264|M.vanbaalenii_PYR-1 GSAGSAGVAGSAG-----------TTGAQGSAGTNGA-NGANGSQGAAGK
MSMEG_0868|M.smegmatis_MC2_155 GAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGADGW
Mb1275c|M.bovis_AF2122/97 GMANQDGDGGDGG-------------------------NGGDGGAGGAG-
Rv3595c|M.tuberculosis_H37Rv GVG---GDAGDGG-------------------------NGGIGGDGGAG-
TH_3810|M.thermoresistible__bu RA------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 EALEEALMGIQVDDEVALRVIDRGVGGITETNVNLASASDAIIIGFNVRA
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK AGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG------
Mvan_1264|M.vanbaalenii_PYR-1 AGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG------
MSMEG_0868|M.smegmatis_MC2_155 VQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSVWK
Mb1275c|M.bovis_AF2122/97 ---------------------GVGGNGGTGGAGGLFGQSG----------
Rv3595c|M.tuberculosis_H37Rv ---------------------GDGGAGGAGGAGGLFGVSG----------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 EGKATELASREGVEIRYYLVIYQAIDDIEKALRGMLKPIYEENQLGRAEI
MUL_2957|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2795|M.marinum_M --------------------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -----AGGEGGEGGDGGKGGAGAE--------GGAGGGGGAGGSGAGGAG
Mvan_1264|M.vanbaalenii_PYR-1 -----AGGEGGEGGAGGAGGDGSE--------GGAGGSGGAGGSGTGGAG
MSMEG_0868|M.smegmatis_MC2_155 SGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSG
Mb1275c|M.bovis_AF2122/97 -----SPGSGAAGGLGGAGG-----------NGG-AGGGGGTGFNPGAPG
Rv3595c|M.tuberculosis_H37Rv -----SSGLGGAAGSGGNGG-----------GGGEPGVAGSPGVGPAGRG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MAV_2780|M.avium_104 --------------------------------------------------
MLBr_01556|M.leprae_Br4923 RALFRSSKVGIIAGCIISSGVVRRNAKVRLLRDNIVVTDNLTVTSLRREK
MUL_2957|M.ulcerans_Agy99 --------------------------------------
MMAR_2795|M.marinum_M --------------------------------------
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --GAGGSGGSGGSGGSGGSGGAAGDSDD----------
Mvan_1264|M.vanbaalenii_PYR-1 --GAGGSGGSGGSGGAGGSGGAAGDSD-----------
MSMEG_0868|M.smegmatis_MC2_155 NGGNGGNGGNGGADGTPGTAGTTGANNP----------
Mb1275c|M.bovis_AF2122/97 DPG------TQGATGANGQHGLNG--------------
Rv3595c|M.tuberculosis_H37Rv GDGNLGQFGPEGAPGQPGQPGQPG--------------
TH_3810|M.thermoresistible__bu --------------------------------------
MAV_2780|M.avium_104 --------------------------------------
MLBr_01556|M.leprae_Br4923 DDVTEVREGFECGMTLGYSDIKEGDVIESYELVEKQRA