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MSSIAVFPEAVSAAAADVANIGRALSAANAAATVPTTNLLAAGTDEISTAVASLFSGHGQAYQRLANQLM AFHDQFAQALTAGASAYTGAEATNASPLQTVEQNALGLINAPTQTLLGRPLIGDGAAGTATNPNGGAGGL LYGNGGAGFNNGATAGAAGGNGGNAGLIGNGGAGGNGGAGGNGGAGAAGGTGDNGGWLYGSGGDGGTGGN ALVAGGTGGNGGAGGDGGAGGVGGDGGAGGVGGVGGDGGAGGVGGVGGDGGWLIGDGGAGGQGGVGGMGG TGGAGGSGVAGAHGGNATSAVAAFGGDGGAGGDAGHGGTGGDGGNGGQGASGGRGGLLSGAQGVTGTAGD GGTGGDGGLHGAFGAGGDPGTGGGQGSDGNRGADGLGGPAFDGARGADGNPG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2853 | - | - | 100% (402) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_4489 | - | e-117 | 54.11% (414) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_4399 | - | e-116 | 52.37% (443) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3402 | PE_PGRS51 | 1e-121 | 51.24% (484) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 7e-77 | 55.63% (284) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv3367 | PE_PGRS51 | 1e-118 | 53.67% (449) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 2e-12 | 38.46% (91) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_4284c | - | 2e-35 | 35.21% (284) | hypothetical protein MAB_4284c |
| M. marinum M | MMAR_1162 | - | 1e-152 | 64.89% (487) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 2e-22 | 40.72% (167) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 9e-63 | 45.62% (331) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-39 | 42.91% (268) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 4e-75 | 47.85% (326) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2853|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1162|M.marinum_M --------------------------------------------------
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_2853|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1162|M.marinum_M --------------------------------------------------
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP--
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_2853|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1162|M.marinum_M --------------------------------------------------
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------MVTFGGGATPTP
Mvan_1264|M.vanbaalenii_PYR-1 ------------------------------------WYVVSFGGSGAPTP
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_2853|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1162|M.marinum_M --------------------------------------------------
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK ----------------------------------------TSLGAAAVDL
Mvan_1264|M.vanbaalenii_PYR-1 ----------------------------------------NNLAASLVDL
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_2853|M.ulcerans_Agy99 ------------------------------------MSSIAVFPEAVSAA
MMAR_1162|M.marinum_M ------------------------------------MSSMAVFPEAVSAA
Mb3402|M.bovis_AF2122/97 ------------------------------------MSFVVAVPEALAAA
Rv3367|M.tuberculosis_H37Rv ------------------------------------MSFVVAVPEALAAA
Mflv_5091|M.gilvum_PYR-GCK S------------------------GTSCG----------LICNGQDGTG
Mvan_1264|M.vanbaalenii_PYR-1 S------------------------GTSCG----------LICNGQDGTG
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----------------------------------------MSIIDFILNL
MAV_4827|M.avium_104 ----------------------------------------MNIVLGVSMA
MUL_2853|M.ulcerans_Agy99 AADVANIGRALSAANAAATVPTTNLLAAGTDEISTAVASLFSGHGQAYQR
MMAR_1162|M.marinum_M AANVANIGRALSAANAAATVPTTNLLAAGTDEISTAVASLFSGHGQAYQR
Mb3402|M.bovis_AF2122/97 ASDVANIGSALSAANAAAAAGTTGLLAAGADEVSAALASLFSGHAVSYQQ
Rv3367|M.tuberculosis_H37Rv ASDVANIGSALSAANAAAAAGTTGLLAAGADEVSAALASLFSGHAVSYQQ
Mflv_5091|M.gilvum_PYR-GCK QN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGG--NGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1 QN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGG--NGGNGGNGL
MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG---NGGNGGVGW
TH_3810|M.thermoresistible__bu -----------------------VDGDGGSGGRTGLFSKLSRGGDGGDGG
MLBr_01183|M.leprae_Br4923 --------MPLFLN------AEPQALTAAANTLEGLSAATVASNAAAAQL
MAB_4284c|M.abscessus_ATCC_199 FRDPVEAASYVADPEAALANAGLSAVSAAQVGAVMPVVAESVASNYGYQS
MAV_4827|M.avium_104 PSSIQMVVLEGEYADGATVEEDAIDVTGADDAATASAPDRVISAILGTRE
.. . .
MUL_2853|M.ulcerans_Agy99 LANQLMAFHDQFAQALTAGASAYTGAEATNASPLQTVEQNALGLINAPTQ
MMAR_1162|M.marinum_M LANQLMAFHDQFAQALTAGASAYTGAEATNASPLQTVEQNALGLINAPTQ
Mb3402|M.bovis_AF2122/97 VAAQATALHDQFVQALTGAGGSYALTEAAN------VQQNLLNAINAPTQ
Rv3367|M.tuberculosis_H37Rv VAAQATALHDQFVQALTGAGGSYALTEAAN------VQQNLLNAINAPTQ
Mflv_5091|M.gilvum_PYR-GCK GGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVG--APGVAGATGA
Mvan_1264|M.vanbaalenii_PYR-1 GSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVG--APGVAGATGA
MSMEG_0868|M.smegmatis_MC2_155 AGLDGGNGGSGG--LLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGG
TH_3810|M.thermoresistible__bu LGGNGGHGGGTGIISLLSLAGNGGNGGNGYR---------TTDNNALDGG
MLBr_01183|M.leprae_Br4923 TTEIAPPAADDVSILLAHFFSGHGR---------------QYQAHASQGA
MAB_4284c|M.abscessus_ATCC_199 QWVNTGNPIHDLSGNLQNYYAAQPDGPSILSPSLLSPRDNDFLSHNDTDF
MAV_4827|M.avium_104 GAADAGLQLSSIGVTWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALA
MUL_2853|M.ulcerans_Agy99 TLLGRPLIGDGAAGTATNPNGGAGGLLYGNGGAGFNN-------------
MMAR_1162|M.marinum_M TLLGRPLIGDGAAGTATNPNGGAGGLLYGNGGAGFNN-------------
Mb3402|M.bovis_AF2122/97 ALLGRPLIGDGAVGTASSPDGQDGGLLFGNGGAGYNS-------------
Rv3367|M.tuberculosis_H37Rv ALLGRPLIGDGAVGTASSPDGQDGGLLFGNGGAGYNS-------------
Mflv_5091|M.gilvum_PYR-GCK TGVTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG-------------
Mvan_1264|M.vanbaalenii_PYR-1 TGVTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG-------------
MSMEG_0868|M.smegmatis_MC2_155 TGGTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPN
TH_3810|M.thermoresistible__bu HGGNGGNVG-----FFSLFNLGGAGGWGGSGVDG----------------
MLBr_01183|M.leprae_Br4923 TNHQDLIQS------LLTSSSAYAGTETANHDSL----------------
MAB_4284c|M.abscessus_ATCC_199 ASHNPIASGNQVMSPSGNVDSFNRGPLLDLSFGDLQFGN-----------
MAV_4827|M.avium_104 QNVGGAMGYERTAVLLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDA
.
MUL_2853|M.ulcerans_Agy99 -GATAGAAGGNGGNAGLIGNGGAGGNGGAGGNGGAG--------------
MMAR_1162|M.marinum_M -GATAGAAGGNGGNAGLIGNGGAGGNGGAG--------------------
Mb3402|M.bovis_AF2122/97 -AATPGMAGGNGGNAGLIGNGGTGGSGGAG--------------------
Rv3367|M.tuberculosis_H37Rv -AATPGMAGGNGGNAGLIGNGGTGGSGGAG--------------------
Mflv_5091|M.gilvum_PYR-GCK -AVGSAGAAGEAGETGTWG--NAGLPGKAGDAGGAG--------------
Mvan_1264|M.vanbaalenii_PYR-1 -AVGSAGTAGSAGAPGVWG--NAGLPGAAGAAGGAG--------------
MSMEG_0868|M.smegmatis_MC2_155 VTVGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVD
TH_3810|M.thermoresistible__bu --VDVVGGNPDGGTPGAHG--ESHTPGVYTDR------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -RDTTAIGDGAVAVGGSNSGPIASGQGSTAVNGDVR--------------
MAV_4827|M.avium_104 AGQLSAMVAGLEKLESLPGGLLLVGSGVDVAPLKQVLQT-----------
MUL_2853|M.ulcerans_Agy99 ------------------------------------------AAGGTGDN
MMAR_1162|M.marinum_M ------------------------------------------AAGGTGGN
Mb3402|M.bovis_AF2122/97 ------------------------------------------AAGGAGGS
Rv3367|M.tuberculosis_H37Rv ------------------------------------------AAGGAGGS
Mflv_5091|M.gilvum_PYR-GCK --AVGAAGAAG------TVGTAGATGGTG---------------TGANGG
Mvan_1264|M.vanbaalenii_PYR-1 --AIGTAGVAG------AAGTAGATGGTG---------------VGGNGG
MSMEG_0868|M.smegmatis_MC2_155 GHAIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGG
TH_3810|M.thermoresistible__bu --------------------------------------------QGEDGE
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------------------------------DSNIINAD
MAV_4827|M.avium_104 -------------------------------------TTFLDVSVAEEPE
MUL_2853|M.ulcerans_Agy99 GGWLYGSGGDGGTG-------------------GNALVAGGTGGNGGAG-
MMAR_1162|M.marinum_M GGWLYGSGGAGGAG-------------------GNALVAGGTGGNGGAGG
Mb3402|M.bovis_AF2122/97 GGWLYGNGGNGGIG-------------------GNAIVAGGAGGNGGAGG
Rv3367|M.tuberculosis_H37Rv GGWLYGNGGNGGIG-------------------GNAIVAGGAGGNGGAGG
Mflv_5091|M.gilvum_PYR-GCK AGGVGGVGGTGAAG--------------AAGGAGGLGETGTTGGAGGVGG
Mvan_1264|M.vanbaalenii_PYR-1 AGQAGGIGGTGAAG--------------AAGQAGTAGETGVTGGVGGIGG
MSMEG_0868|M.smegmatis_MC2_155 HSTGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGE
TH_3810|M.thermoresistible__bu DGTGTGIGGRGGNG------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 HGSNVGVDQSQTRVG------------------GDYTNVSGHGSADIDKS
MAV_4827|M.avium_104 TALARGAALAAANAP------------LFASSTAALAYAQDPGTGAVDQY
MUL_2853|M.ulcerans_Agy99 -----GDGGAG---------------------------------------
MMAR_1162|M.marinum_M AAGLWGNGGAGGHGGSGLAGNSGVNPTPTHDTALNGADGDSNI-YDAATN
Mb3402|M.bovis_AF2122/97 AAGLWGSGGSGGQGGNGLTGNDGVNPAPVTNPALNGAAGDSN--IEPQTS
Rv3367|M.tuberculosis_H37Rv AAGLWGSGGSGGQGGNGLTGNDGVNPAPVTNPALNGAAGDSN--IEPQTS
Mflv_5091|M.gilvum_PYR-GCK Q--GTAGGTGGVGGIGGAGSTGAVGGVGGKG----IQGGQG---------
Mvan_1264|M.vanbaalenii_PYR-1 Q--GTEGGTGGVGGVGGVGATGGAGGVGGKG----IQGGQG---------
MSMEG_0868|M.smegmatis_MC2_155 IYSGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASG
TH_3810|M.thermoresistible__bu ------------------GSSSGTHPMAEDG-------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 VTVVDDHSQRNTTNINDSFNTDRSTNIGSGNTTNTEIGSHN---------
MAV_4827|M.avium_104 SLPDYLYVPVDPEPGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRR
MUL_2853|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1162|M.marinum_M TVSATPGTDGTPGGAGVTGGNGGAGGSAS-QPVTSLTATASDGGNGAQGG
Mb3402|M.bovis_AF2122/97 VLIGTQGGDGTPGGAGVNGGNGGAGGDANGNPANTSIANAGAGGNGAAGG
Rv3367|M.tuberculosis_H37Rv VLIGTQGGDGTPGGAGVNGGNGGAGGDANGNPANTSIANAGAGGNGAAGG
Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSMGS------------------AGATG
Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSMGE------------------AGATG
MSMEG_0868|M.smegmatis_MC2_155 TAKAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANG
TH_3810|M.thermoresistible__bu -----EHVKALDGRPGLDGG----------------------------NG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --QANIGTSTSAGGSAAVGGNAGLAGNAG----------------LAGNA
MAV_4827|M.avium_104 PVLLVGSGLAVVGISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQ
MUL_2853|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1162|M.marinum_M QGGADGGTGGVAGVAASYNGVAIGGNGGNGGTGGTGTDGLAGSGG-----
Mb3402|M.bovis_AF2122/97 DGGANGGAGGAGGQAAS-AGSSVGGDGGNGGAGGTGTNGHAGGAGGAGGQ
Rv3367|M.tuberculosis_H37Rv DGGANGGAGGAGGQAAS-AGSSVGGDGGNGGAGGTGTNGHAGGAG-----
Mflv_5091|M.gilvum_PYR-GCK GKGGNGGNGGRGGLFG---------------KGGNAGNGAD---------
Mvan_1264|M.vanbaalenii_PYR-1 GKGGNGGNGGRGSLFG---------------RGGNAGNGGN---------
MSMEG_0868|M.smegmatis_MC2_155 AVGGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPN
TH_3810|M.thermoresistible__bu SHGGNGGHGGRGGFLG----------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GLAGNAGLAGNAGLAGN---------------------------------
MAV_4827|M.avium_104 APAPPPVQASAPQPKISVPEPVAAPKPLSPPVAAPLPAAPP---------
MUL_2853|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1162|M.marinum_M ------------------------------GSGGAGGRGGWLIGNGGAGG
Mb3402|M.bovis_AF2122/97 AASAGSSVGGDGGNGGAGGTGTNGHAGGAGGAGGAGGRGGWLVGSGGNGG
Rv3367|M.tuberculosis_H37Rv ------------------------------GAGGAGGRGGWLVG---NGG
Mflv_5091|M.gilvum_PYR-GCK --------------------------------GGTGGAGGAGGTGG-TGG
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------GGTGGNGGNGGTGG-TGG
MSMEG_0868|M.smegmatis_MC2_155 GPAGTTIDKGK-------------------AAGGNGGDGGFNGTGGATGG
TH_3810|M.thermoresistible__bu -------------------------------IGGSGGWGGHGGNGGDTDA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------AGLAGNAGLAGNAGLAGN
MAV_4827|M.avium_104 --------------------------------PAAPPLPEAPPIPAAPPV
MUL_2853|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1162|M.marinum_M AGGAGG-----------------AGGNGAIGGDGGAAGFTGSNNDSAAST
Mb3402|M.bovis_AF2122/97 NGGNGA-----------------AGGNGAIGGTGGAGGVPANQGGNSALG
Rv3367|M.tuberculosis_H37Rv NGGNGA-----------------AGGNGAIGGTGGAGGVPANQGGNSALG
Mflv_5091|M.gilvum_PYR-GCK AGGTGG-----------------TGGTGGIGGAGSTGGTGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 NGGTGG-----------------TGGTGGIGGAGSTGGTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 RGGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTFVNAGANGNGGAGG
TH_3810|M.thermoresistible__bu DG------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AGLAGNAG---------------LAGNAGLAGNAGLAGNAGLAGNAGLAG
MAV_4827|M.avium_104 VPVPVVVPPVPVPVPVRIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQP
MUL_2853|M.ulcerans_Agy99 ------GVGGDGGAGGVGGVGGDGGAGGVGGVGGDGGWLIGDGGAGGQGG
MMAR_1162|M.marinum_M LYGAHGGTGGDGGAGGTGGHGGAGGAGGAGGVGGDGGWLIGDGGAGGQGG
Mb3402|M.bovis_AF2122/97 -TQPVSGDGGDGGNGGTGGTGGRGGDGGSGGAGGASGWLMGNGGNGGNGG
Rv3367|M.tuberculosis_H37Rv -TQPVGGDGGDGGNGGTGGTGGRGGDGGSGGAGGASGWLMGNGGNGGNGG
Mflv_5091|M.gilvum_PYR-GCK TGGTG-GTGGTGGTGGTGGKGGTGGTGGAGGTG----GDGGTGGTGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 TGGTG-GTGGTGGTGGTGGKGGTGGTGGDGGTG----GTGGTGGTGGTGG
MSMEG_0868|M.smegmatis_MC2_155 AGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLGNGGKGGNGGNGG
TH_3810|M.thermoresistible__bu ------GNGGDGGNGGSAGRGGTGGLRGVFGIN-----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ----NAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAGLAGNAAV
MAV_4827|M.avium_104 PSPPQVGGTVPQSPPQHQTPPGEGTPPKPDGPGNYGGGHVPTPGAGGSGG
MUL_2853|M.ulcerans_Agy99 VG---------GMGGTGGAGGSG-------------VAGAHGGNATSA--
MMAR_1162|M.marinum_M IG---------GMGGTGGAGGSG-------------VAGAHGGNATSS--
Mb3402|M.bovis_AF2122/97 TG---------GSGGVGGNGGIG-------------GDGAGGGNATSTSS
Rv3367|M.tuberculosis_H37Rv TG---------GSGGVGGNGGIG-------------GDGAGGGNATSTSS
Mflv_5091|M.gilvum_PYR-GCK TG---------GTGGTGGTGGAG-----------DGTGGTGGTGG----T
Mvan_1264|M.vanbaalenii_PYR-1 TG---------GTGGTGGTGGAG-----------DGLGGTGGTGG----T
MSMEG_0868|M.smegmatis_MC2_155 NGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATGGNGGNGGNGDAD
TH_3810|M.thermoresistible__bu ----------------GGNGRAG---------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 AG---------NAAVAGNAAVAG--------------NAAVGGVLNTGVS
MAV_4827|M.avium_104 SGG--------GHVPTPGAGGSG---------------GSGGGHVPTPGT
MUL_2853|M.ulcerans_Agy99 --VAAFGGDGG-----------------AGGDAGHGG-------------
MMAR_1162|M.marinum_M --IAAFGGDGG-----------------AGGDAGHGG-------------
Mb3402|M.bovis_AF2122/97 IPFDAHGGNGG-----------------AGGDAGHGG-------------
Rv3367|M.tuberculosis_H37Rv IPFDAHGGNGG-----------------AGGDAGHGG-------------
Mflv_5091|M.gilvum_PYR-GCK GGQGGQGGQGG-----------------TGGTGGQGG-LGGGGGTG----
Mvan_1264|M.vanbaalenii_PYR-1 GGFGGQGGQGG-----------------TGGTGGQGG-LGGVGGTG----
MSMEG_0868|M.smegmatis_MC2_155 GHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGTLGATNGTGGAAT
TH_3810|M.thermoresistible__bu --LGGRGXXXX-----------------GGGVG-----------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GAIGGSSHVGG------------AINESLGGSGSVGG-------------
MAV_4827|M.avium_104 GGPGGTGGSGG-------------GHVPTPGAGTPGG-------------
MUL_2853|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1162|M.marinum_M --------------------------------------------------
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------------GQGGTGGTGGQGGTGGTGGTGGTG-------
Mvan_1264|M.vanbaalenii_PYR-1 -------------------GTGGTGGTGGQGGTGGTGGTGGTG-------
MSMEG_0868|M.smegmatis_MC2_155 IVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGTIEANGPSAVASG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_2853|M.ulcerans_Agy99 --TGGDGGNGGQGASGGRGGLLSGAQGVTGTAGDGGTGGDGGLHG-----
MMAR_1162|M.marinum_M --MGGDGGNGGQGASGGRGGLLSGAQGVTGTAGDGGTGGAGGLHG-----
Mb3402|M.bovis_AF2122/97 --TGGDGGDGGHAGTGGRGGLLAGQHANSGNGGGGGTGGAGGTHG-----
Rv3367|M.tuberculosis_H37Rv --TGGDGGDGGHAGTGGRGGLLAGQHANSGNGGGGGTGGAGGTHG-----
Mflv_5091|M.gilvum_PYR-GCK -GTGGAGGDGGLGGLGGFGGSGGTGGQGGLGGPGGSTGGAGGAGG--QAG
Mvan_1264|M.vanbaalenii_PYR-1 -GTGGAGGDGGLGGLGGFGGVGGTGGQGGQGGPGGSTGGAGGAGG--QAG
MSMEG_0868|M.smegmatis_MC2_155 IGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATGTATGGDGGKATG
TH_3810|M.thermoresistible__bu --AAVRSGNGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVSREG-----
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ---STAVGGGAHTGVGGGVSTGVGVGSHVGGGISESLGGSGSVGG-----
MAV_4827|M.avium_104 ----SGGGHLPFPGAGSTPG-GSGGGHLPTPGAGTPGGGLGGFGG-----
MUL_2853|M.ulcerans_Agy99 --------------------AFGAG--GDPGTGGGQGSDGNRGADG----
MMAR_1162|M.marinum_M --------------------AFGAG--GDPGTGGGQGSDGKLGADG----
Mb3402|M.bovis_AF2122/97 --------------------TPGSGNAGGTGTGNADSTNGGPGSDG----
Rv3367|M.tuberculosis_H37Rv --------------------TPGSGNAGGTGTGNADSTNGGPGSDG----
Mflv_5091|M.gilvum_PYR-GCK TAGKGGLFG----GSGSAGKAGATGAAGASGGKGAQGATGAQGATG----
Mvan_1264|M.vanbaalenii_PYR-1 VAGKGGLFG----GSGSAGTAGVTGASGASGGKGAQGATGAQGATG----
MSMEG_0868|M.smegmatis_MC2_155 TASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEASNGGVAGNGGNAL
TH_3810|M.thermoresistible__bu -------------------IMPSSRAASARAG------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 ------------------STAVGGGAHTGVGGGVSTGVGVGSHVGG----
MAV_4827|M.avium_104 --------------------GHAPAPGGGLGGGGGHAPAPGGGLGG----
MUL_2853|M.ulcerans_Agy99 ----------LGGPAFDGARGADGNPG-----------------------
MMAR_1162|M.marinum_M ----------LGGAAFDGARGADGNPG-----------------------
Mb3402|M.bovis_AF2122/97 ----------LGGDAFNGSRGTDGNPG-----------------------
Rv3367|M.tuberculosis_H37Rv ----------LGGDAFNGSRGTDGNPG-----------------------
Mflv_5091|M.gilvum_PYR-GCK --AQGATG-ATGAAGKAGATGAAGAAGAAGSAG-----------TTGAQG
Mvan_1264|M.vanbaalenii_PYR-1 --AQGATG-ATGASGAQGSAGSAGSAGVAGSAG-----------TTGAQG
MSMEG_0868|M.smegmatis_MC2_155 VMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNIAAIHGAITDSTA
TH_3810|M.thermoresistible__bu ---------AACASSTSRSRRSFCCSRA----------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 -----------GISESLGGSGSVGGSTAVGGG------------------
MAV_4827|M.avium_104 ----------FGGGHSGGGLGGLGGGHK----------------------
MUL_2853|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1162|M.marinum_M --------------------------------------------------
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK SAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGEDGDAGSG
Mvan_1264|M.vanbaalenii_PYR-1 SAGTNGA-NGANGSQGAAGKAGATGTTGATG--------AAGDAGDPGSE
MSMEG_0868|M.smegmatis_MC2_155 ISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSSAVAGNGGDGGVN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 --AHTGVGGGVNTGVGVGSHVGGG---------------ISESLGGSGSV
MAV_4827|M.avium_104 --------------------------------------------------
MUL_2853|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1162|M.marinum_M --------------------------------------------------
Mb3402|M.bovis_AF2122/97 --------------------------------------------------
Rv3367|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GSG-INGGAGGAGG-----------AGGEGGEGGDGGKGGAGAE------
Mvan_1264|M.vanbaalenii_PYR-1 AVD-INGGAGGAGG-----------AGGEGGEGGAGGAGGDGSE------
MSMEG_0868|M.smegmatis_MC2_155 GTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGNGGDGSEPGPGGN
TH_3810|M.thermoresistible__bu --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 GGSTAVGGGAHTSAINDALGGSGSVGGSTAVGGGAHTSAINESMNSSINA
MAV_4827|M.avium_104 --------------------------------------------------
MUL_2853|M.ulcerans_Agy99 ------------------------------------------------
MMAR_1162|M.marinum_M ------------------------------------------------
Mb3402|M.bovis_AF2122/97 ------------------------------------------------
Rv3367|M.tuberculosis_H37Rv ------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --GGAGGGGGAGGSGAGGAG--GAGGSGGSGGSGGSGGSGGAAGDSDD
Mvan_1264|M.vanbaalenii_PYR-1 --GGAGGSGGAGGSGTGGAG--GAGGSGGSGGSGGAGGSGGAAGDSD-
MSMEG_0868|M.smegmatis_MC2_155 GAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPGTAGTTGANNP
TH_3810|M.thermoresistible__bu ------------------------------------------------
MLBr_01183|M.leprae_Br4923 ------------------------------------------------
MAB_4284c|M.abscessus_ATCC_199 SHSSSMNESFGSSMGSHGAAGTGFEAQGHAQGHASETAHTTLPGAEHH
MAV_4827|M.avium_104 ------------------------------------------------