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MNSDTGEPGGQGGQGGAGGRGGAGGAGGRGGAGGRGGAGGAGGPGGQGGRGGDGGPGGAPGIGGRPGEGG PGGAGGEPGPGGTPGQPGQPGQPGQPGSPGH
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_2795 | - | - | 100% (101) | PE-PGRS family protein |
M. marinum M | MMAR_5344 | - | 1e-26 | 56.84% (95) | PE-PGRS family protein |
M. marinum M | MMAR_1442 | - | 3e-26 | 57.58% (99) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3543 | PE_PGRS57 | 1e-27 | 57.00% (100) | PE-PGRS family protein |
M. gilvum PYR-GCK | Mflv_5091 | - | 9e-31 | 62.50% (96) | triple helix repeat-containing collagen |
M. tuberculosis H37Rv | Rv3595c | PE_PGRS59 | 5e-29 | 54.87% (113) | PE-PGRS family protein |
M. leprae Br4923 | MLBr_01556 | infB | 2e-12 | 48.78% (82) | translation initiation factor IF-2 |
M. abscessus ATCC 19977 | MAB_0321c | - | 2e-19 | 45.71% (105) | hypothetical protein MAB_0321c |
M. avium 104 | MAV_2780 | - | 2e-15 | 58.67% (75) | hypothetical protein MAV_2780 |
M. smegmatis MC2 155 | MSMEG_0868 | - | 9e-22 | 50.98% (102) | hypothetical protein MSMEG_0868 |
M. thermoresistible (build 8) | TH_3810 | - | 2e-17 | 51.76% (85) | PUTATIVE - |
M. ulcerans Agy99 | MUL_2957 | - | 1e-36 | 71.00% (100) | PE-PGRS family protein |
M. vanbaalenii PYR-1 | Mvan_1264 | - | 1e-30 | 62.50% (96) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3595c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3595c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3595c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -----------------------------------------------MMF MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 ------------------MSFVLIAPEFVTAAAGDLTNLGSSISAANASA Rv3595c|M.tuberculosis_H37Rv ------------------MSFVIAVPEFLSAAATDLANLGSTISAANAAA Mflv_5091|M.gilvum_PYR-GCK ----------------------------MVTFGGGATPTPTSLGAAAVDL Mvan_1264|M.vanbaalenii_PYR-1 LAPPGGPGPISAAIQLTSTGSEATEPWYVVSFGGSGAPTPNNLAASLVDL MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -----------MAGKARVHELAKELGVTSKEVLARLNEQGEFVKSASSTV Mb3543|M.bovis_AF2122/97 ASATTQVLAAGADEVSAR---IAALFGGFGLEYQAISAQVAAYHQRFVQA Rv3595c|M.tuberculosis_H37Rv SIPTTGVLAAGADDVSAA---IAALFGAHAQAYQTISAQAATFHAQFVQT Mflv_5091|M.gilvum_PYR-GCK SGTSCGLICNGQDGTGQN---GGILFGNGGSGWNSDVVGMDGGNGGNGGL Mvan_1264|M.vanbaalenii_PYR-1 SGTSCGLICNGQDGTGQN---GGILFGNGGSGWNSEIAGVSGGNGGNAGL MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQFWVVSPIGSTLGGVINTISGQYLIGNGINGTA TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 EAPVARRLRESFGGIKPAADKGAEQVATKAQAKRLGESLDQTLDRALDKA Mb3543|M.bovis_AF2122/97 LSTGAGAY-----ASAEAAAAEQIVLGVINAPTQALLGRPLIGDGANATT Rv3595c|M.tuberculosis_H37Rv LSAGAGAY-----ANAEAANVQQSLLNAINAPTQALLGRPLIGDGADGTA Mflv_5091|M.gilvum_PYR-GCK FGGNGGNG-----GNGLGGGNGG---NGGNAGAFALFGNGGNG-GNGGVG Mvan_1264|M.vanbaalenii_PYR-1 FGGNGGNG-----GNGLGSGDGG---NGGDAGLFSLFGRGGNG-GNGGVG MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 DNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFGNGGNGGVGWAGL TH_3810|M.thermoresistible__bu VDGDGGSG-----------------------GRTGLFSKLSRGGDGGDGG MAV_2780|M.avium_104 -----------------------------------MFG------------ MLBr_01556|M.leprae_Br4923 VAGNGATTAAPVQVDHSAAVVPIVAGEGPSTAHREELAPPAGQPSEQPGV Mb3543|M.bovis_AF2122/97 PGGAGGAGGLLFGNGGAG-----AAGA-PGQAGGPGGPAGLWGNGGPGGA Rv3595c|M.tuberculosis_H37Rv PGQNGGAGGLLYGNGGNG-----AAGVNAGIAGGSGGAAGLIGNGGSGGA Mflv_5091|M.gilvum_PYR-GCK VVGATGAVGAPGVAGATG-----ATGVTSGVVGGNGEDAVGYGATGAAGA Mvan_1264|M.vanbaalenii_PYR-1 IAGATGAVGAPGVAGATG-----ATGVTSNVTGGNGADAVGYGATGAAGA MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -----------------------MANIISNGPDGDAGATG---------- MSMEG_0868|M.smegmatis_MC2_155 DGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTGGTG TH_3810|M.thermoresistible__bu LGGNGGHGG--------------GTGIISLLSLAGNGGNGGNGYRTTDNN MAV_2780|M.avium_104 -----------------------GAAMLVLAVGCGGGHKGG--------- MLBr_01556|M.leprae_Br4923 PLPGQQGTPAAPHPGHPG----MPTGPHPGPAPKPGGRPPRVGNNPFSSA Mb3543|M.bovis_AF2122/97 GGSGGGTGGAGGAG--GWLFGVGGAGGVGGAGGGTGGAGGPGGLIWGGGG Rv3595c|M.tuberculosis_H37Rv GGAG-AAGGSGGQG--GLLYGNGGAG--------------------GNGG Mflv_5091|M.gilvum_PYR-GCK AGAAGAAGAAGAVGSAGAAGEAGETGTWGNAGLPGKAGDAGGAGAVGAAG Mvan_1264|M.vanbaalenii_PYR-1 AGAAGAAGKAGAVGSAGTAGSAGAPGVWGNAGLPGAAGAAGGAGAIGTAG MMAR_2795|M.marinum_M ---------------------------------------MN--------- MUL_2957|M.ulcerans_Agy99 ---------------------------------------MS--------- MAB_0321c|M.abscessus_ATCC_199 --------------AQGSQGATGAAG------------AMANCNWIDDDC MSMEG_0868|M.smegmatis_MC2_155 GIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVTVGS TH_3810|M.thermoresistible__bu ALDGGHGGNGGNVGFFSLFN------------------------------ MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 QSVARPIPRPPAPRPSASPSSMSPRPGGAVGGGGPRPPRTGVPRPGGGRP Mb3543|M.bovis_AF2122/97 AGGVGGAGGGTGGAGGRAELLFG-AGGAGGAGGAGTDGGPGATGGTGGHG Rv3595c|M.tuberculosis_H37Rv AATIPGGNGGAGGAGG-NAWLFG-NGGAGGLGAAGAAGAAGVNPLT---- Mflv_5091|M.gilvum_PYR-GCK AAGTVGTAGATGGTGTGANGGAGGVGGVGGTGAAGAAGGAGGLGETG--- Mvan_1264|M.vanbaalenii_PYR-1 VAGAAGTAGATGGTGVGGNGGAGQAGGIGGTGAAGAAGQAGTAGETG--- MMAR_2795|M.marinum_M -----SDTGEPGGQGGQ--------GGAGG-------------------- MUL_2957|M.ulcerans_Agy99 -----SDTGEPGGQDDQ--------GGAGG-------------------- MAB_0321c|M.abscessus_ATCC_199 AT--RGGTGGTGGNGGP--------GGAGGPGGHGGVIDFEVETFMDGVT MSMEG_0868|M.smegmatis_MC2_155 ET--RGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGHA TH_3810|M.thermoresistible__bu ----LGGAGGWGGSGVDGVDVVGGNPDGGTPGAHGESHTPGVYTDRQ--- MAV_2780|M.avium_104 ----PSTTSTTTPTTTP--------------------------------- MLBr_01556|M.leprae_Br4923 GAPVGGRSDAGGGNYRGGGVGALPGGGSGGFRGRPGGGGHGGGGRPG--- . . Mb3543|M.bovis_AF2122/97 GVGGDGGWLAPGGAGGAGGQGGAGGAGSDG-------------------G Rv3595c|M.tuberculosis_H37Rv ---------VPAGQGSMGNNGEPGGPGQPG-------------------T Mflv_5091|M.gilvum_PYR-GCK ---------TTGGAGGVGGQGTAGGTGGVGGI-----------------G Mvan_1264|M.vanbaalenii_PYR-1 ---------VTGGVGGIGGQGTEGGTGGVGGV-----------------G MMAR_2795|M.marinum_M -------------RGGAGGAGGRGGAGGRGGA-----------------G MUL_2957|M.ulcerans_Agy99 -------------RGGAG-------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------LQAKGGRGGNGGHGGAGGTGGTGGK-----------------G MSMEG_0868|M.smegmatis_MC2_155 -------IGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATG TH_3810|M.thermoresistible__bu -----------GEDGEDGTGTGIGGRGGNGGS-----------------S MAV_2780|M.avium_104 -------------STSVVPSTTPGGGGTVP-------------------- MLBr_01556|M.leprae_Br4923 -----------QRGGAAGAFGRPGGAPRRGRK-----------------S Mb3543|M.bovis_AF2122/97 ALGGTGGTGGTGGAGGAGGRGALLLGAGGQGGLGGAGGQGGMGGAGGAGA Rv3595c|M.tuberculosis_H37Rv EFGQTGGTGGTGGTG----------------------------------- Mflv_5091|M.gilvum_PYR-GCK GAGSTGAVGGVGGKGIQGGQG----------------------------- Mvan_1264|M.vanbaalenii_PYR-1 GVGATGGAGGVGGKGIQGGQG----------------------------- MMAR_2795|M.marinum_M G---------AGGPGGQ--------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 GDGDDCEFGRTGGNGGT--------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GDGGHSTGTGIGGNGGIGSVYAY----------------------GNNGA TH_3810|M.thermoresistible__bu SGTHPMAEDGEHVKALDG-------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 KRQKRQEYDSMQAPVVGG-------------------------------- Mb3543|M.bovis_AF2122/97 DNPTGIGGTGGDGGTGGSAGEGGAG----GAAGQLFSASGAAGNAGVGGA Rv3595c|M.tuberculosis_H37Rv ---LSVGGTGGTGGTGGTGGAGGSG----GRGGLLV-------------- Mflv_5091|M.gilvum_PYR-GCK ----LQGGKGGDGGAGGKGGDADSM----GSAGATGGKGGNGGNGGRGGL Mvan_1264|M.vanbaalenii_PYR-1 ----LQGGQGGDGGTGGTGGDATSM----GEAGATGGKGGNGGNGGRGSL MMAR_2795|M.marinum_M ------GGRGGDG---GPGG------------------------------ MUL_2957|M.ulcerans_Agy99 -------GRGGDG---GPGG------------------------------ MAB_0321c|M.abscessus_ATCC_199 ------GGRGGDGNFAGTGGNGGA-------------------------- MSMEG_0868|M.smegmatis_MC2_155 VSGTATGGRGGDGIDGGTGGAGGMGEIYSGADGEATGISAGGDGGSATGA TH_3810|M.thermoresistible__bu ----RPGLDGGNGSHGGNGGHGGRG------------------------- MAV_2780|M.avium_104 ------GGPTGGGGPGGGGGSIPGG------------------------- MLBr_01556|M.leprae_Br4923 ---VRLPHGNGETIRLARGASLSDFAEKIDANPAALVQALFNLGEMVTAT * . .. Mb3543|M.bovis_AF2122/97 GGQGGDGGAGGAGADADQPGATGGTGFAGGAGGAGGAGGSSGAGGTNGSG Rv3595c|M.tuberculosis_H37Rv ----GDGGAG---------------------------------------- Mflv_5091|M.gilvum_PYR-GCK FGKGGNAGNGADG------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 FGRGGNAGNGGNG------------------------------------- MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 DSLGGRGGTSWVQAGYGPTTGGKASGTAKAGHGGKASDGGKGGNGGDALV TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 QSVGDETLELLG-------------------------------------- Mb3543|M.bovis_AF2122/97 GAGGTGGQGGMGGAGGAGADNPTGIGGTGGDGGTGGAAGAGGAGGAAGTG Rv3595c|M.tuberculosis_H37Rv -----------------------GIGGTGGEGGIG--------------- Mflv_5091|M.gilvum_PYR-GCK -----------------------GTGGAGGAGGTGG-------------- Mvan_1264|M.vanbaalenii_PYR-1 -----------------------GTGGNGGNGGTGG-------------- MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 MAAGATGVATGNTAIGGNGGAASANGAVGGNGGFTNI------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 GTGGMIGTTGNAGVGGAGGQGGDGGAGGAGADADQPGATGGTGFAGGAGG Rv3595c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -------------------------------------------------- TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 -------------------------------------------------- Mb3543|M.bovis_AF2122/97 AGGAGGSSGAGGTNGSGGAGGTGGQGGAGGAGGAGADNPTGIGGTGGDGG Rv3595c|M.tuberculosis_H37Rv -----------------ARGGTGGQGGMGGAG------QPGVGGDAGDGG Mflv_5091|M.gilvum_PYR-GCK ------------TGGAGGTGGTGGTGGIGGAG-----STGGTGGTGGTGG Mvan_1264|M.vanbaalenii_PYR-1 ------------TGGNGGTGGTGGTGGIGGAG-----STGGTGGTGGTGG MMAR_2795|M.marinum_M --------------------------------------APGIGGRPG--- MUL_2957|M.ulcerans_Agy99 --------------------------------------APGIGGRPG--- MAB_0321c|M.abscessus_ATCC_199 --------------ILVKCQHDLSLGTHPMDV------SAGTGGNGG--- MSMEG_0868|M.smegmatis_MC2_155 ------------AAIHGSITDSSATSGHGGAA------QGGNGGNGGNGW TH_3810|M.thermoresistible__bu --------------------GFLGIGGSGGWG--------GHGGNGGDTD MAV_2780|M.avium_104 --------------------------------------PTGGGGPGG--- MLBr_01556|M.leprae_Br4923 ---------------SEMNYNVQVVSPEDEDRELLEPFDLTYGEDQGDED * * Mb3543|M.bovis_AF2122/97 TGGAAGAGGAGGAAGTGGTGGMIGTTGNAGVGGAGGQGGDGGAGGAGGAG Rv3595c|M.tuberculosis_H37Rv NG---------------------------GIGGDGGAGGDGGAGGAGGAG Mflv_5091|M.gilvum_PYR-GCK TGGTGGTGGTGGTGGTG------------GTGGKGGTGGTGGAGGTGGDG Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGTGGTGGTGGTG------------GTGGKGGTGGTGGDGGTGGTG MMAR_2795|M.marinum_M ------------------------------EGGPGGAGGEPGPGGT---- MUL_2957|M.ulcerans_Agy99 ------------------------------EGGPGGAGGEPGPGGTSG-- MAB_0321c|M.abscessus_ATCC_199 ------------------------------IGGGGGGGGSVGANGATTGV MSMEG_0868|M.smegmatis_MC2_155 VQAYDPNGPAGTTIDKG-----------KAAGGNGGDGGFNGTGGATGGR TH_3810|M.thermoresistible__bu ADG--------------------------GNGGDGGNGGSAGRGGTGGLR MAV_2780|M.avium_104 -------------------------------GGGSIPGGPTGGGGPGGGG MLBr_01556|M.leprae_Br4923 ELQVRPPVVTVMGHVDHGKTRLLDTIRKANVREAEAGGITQHIGAYQVGV * .. Mb3543|M.bovis_AF2122/97 GSSGAG------------GTNGSGGAGGTGGQGGAGGAGGAGADNPTGIG Rv3595c|M.tuberculosis_H37Rv GLFGVS------------GSSGLGGAAGSGGNGGG--------------- Mflv_5091|M.gilvum_PYR-GCK GTGGTG------------GTGGTGGTGGTGGTGGAG-------DGTGGTG Mvan_1264|M.vanbaalenii_PYR-1 GTGGTG------------GTGGTGGTGGTGGTGGAG-------DGLGGTG MMAR_2795|M.marinum_M --------------------------PGQPGQPGQ--------------- MUL_2957|M.ulcerans_Agy99 -------------------------QPGQPGQPGQ--------------- MAB_0321c|M.abscessus_ATCC_199 FSSSS-----------DCSGPGPQPNPGSPGDPGTS------------VA MSMEG_0868|M.smegmatis_MC2_155 GGDGAGASVWKANGQHSTGQTDTGGNGGRGGDGGTF------------VN TH_3810|M.thermoresistible__bu GVFGIN---------------GGNGRAGLGGRGXXX-------------- MAV_2780|M.avium_104 GS-----------------------IPGVGGGGGGP-------------- MLBr_01556|M.leprae_Br4923 DLDGSE------RLITFIDTPGHEAFTAMRARGAKAT--------DIAIL . . Mb3543|M.bovis_AF2122/97 GTGGDGGTGGAAGAGGAGGAAGTGGTGGMIGTTGNAGVGGAGGQGGDGGA Rv3595c|M.tuberculosis_H37Rv --GGEPGVAGSPGVG----PAGRGGDG----NLGQFGPEGAPGQPG---- Mflv_5091|M.gilvum_PYR-GCK GTGGTGGQGGQGGQGGTGGTGGQGGLGGGGGTGGQGGTGGTGGQGGTGGT Mvan_1264|M.vanbaalenii_PYR-1 GTGGTGGFGGQGGQGGTGGTGGQGGLGGVGGTGGTGGTGGTGGQGGTGGT MMAR_2795|M.marinum_M -PGQPGSPGH---------------------------------------- MUL_2957|M.ulcerans_Agy99 -PGQPGAPGH---------------------------------------- MAB_0321c|M.abscessus_ATCC_199 VSGAQGNPGQAQFLIVP--------------------------------- MSMEG_0868|M.smegmatis_MC2_155 -AGANGNGGAGGAGGVSEGEGGTGGHGGDGGRGGDGALGGNGGTGGVGLG TH_3810|M.thermoresistible__bu -XGGGVGAAVRSGNGVFSGGGGTPSAGFGVPTTIQFPAGSCTSRAVS--- MAV_2780|M.avium_104 -GGGGGCVGNVCGAYP---------------------------------- MLBr_01556|M.leprae_Br4923 VVAADDGVMPQTVEAINHAQAADVPIVVAVNKIDKEGADPAKIRGQLTEY . Mb3543|M.bovis_AF2122/97 GGAGADADQPGATGGTGFAGGAGGAGGAGGSSGA---------------G Rv3595c|M.tuberculosis_H37Rv --------QPGQPG------------------------------------ Mflv_5091|M.gilvum_PYR-GCK G-------GTGGTGGTGGAGGDGGLGGLGGFGGS---------------G Mvan_1264|M.vanbaalenii_PYR-1 G-------GTGGTGGTGGAGGDGGLGGLGGFGGV---------------G MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 NGGKGGNGGNGGNGGTYVDPSHTGAGGNGGNGGAGRIRVNNGTATGTATG TH_3810|M.thermoresistible__bu --------REGIMPSSRAASARAG-------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 GLVAEDFGGDTMFIDISAKVGTNIEALLEAVLLTADAALDLRANSGMEAQ Mb3543|M.bovis_AF2122/97 GTNGSGGAGGTGG-QGGAGGAGISFSN--------GSNGGTGGTGGVGGT Rv3595c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GTGGQGGLGGPGGSTGGAGGAGGQAGT--------AGKGGLFGGSGSAGK Mvan_1264|M.vanbaalenii_PYR-1 GTGGQGGQGGPGGSTGGAGGAGGQAGV--------AGKGGLFGGSGSAGT MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GNGGNGGNGDADGHRGGKGGDGGEALIRATVIGSNASGTATGGDGGNGGT TH_3810|M.thermoresistible__bu ------AACASSTSRSRRSFCCSRA------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 GVAIEAHLDRGRGPVATVLVQRGTLRIGDSVVAGDAYGRVRRMVDEHGVD Mb3543|M.bovis_AF2122/97 GGDGGNAG------------------------------------------ Rv3595c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK AGATGAAG------------------------------------------ Mvan_1264|M.vanbaalenii_PYR-1 AGVTGASG------------------------------------------ MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 LGATNGTGGAATIVAYNVVQANPQASGTATDGHGGSGINGGHGGNGGQGT TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 IEAALPSSPVQVIGFTSVPGAGDN-------------------------- Mb3543|M.bovis_AF2122/97 -------------TGAGDPGKGGTGGTGGSGGAGGSGGANFNGGTGGTGG Rv3595c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------ASGGKGAQGATGAQGATGAQGATGATGAAGKAGATGA Mvan_1264|M.vanbaalenii_PYR-1 -------------ASGGKGAQGATGAQGATGAQGATGATGASGAQGSAGS MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 IEANGPSAVASGIGAGGNGGDGIDGGLGGNGGDGVVNTTANAANPGSATG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ----------FLVVDEDRIARQIADRRSARKRNALAARSRKRISLEDLDS Mb3543|M.bovis_AF2122/97 TGGTGGKGGMG-----------------------------GIAGDGGPGG Rv3595c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK AGAAGAAGSAG-----------------------------TTGAQGSAGT Mvan_1264|M.vanbaalenii_PYR-1 AGSAGVAGSAG-----------------------------TTGAQGSAGT MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 TATGGDGGKATGTASQGGNGGPSWVQSGYGSTLGGNATGTATAGKGGEAS TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ALKETSQLNLILKGDNAGTVEALEEALMGIQVDDEVALRVIDRGVGGITE Mb3543|M.bovis_AF2122/97 DGGNAGVGGKGGTNGNGGSGGTGGTGGPGGSGGAPT-------------- Rv3595c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK NGANGANGSQGAAGKAGATGTTGATGAAGEDGDAGS-------------- Mvan_1264|M.vanbaalenii_PYR-1 NGANGANGSQGAAGKAGATGTTGATGAAGDAGDPGS-------------- MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 NGGVAGNGGNALVMAAGTTGVATGNTATGGDGGAATTAGATGGAGGFSNI TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 TNVNLASASDAIIIGFNVRAEGKATELASREGVEIR-------------- Mb3543|M.bovis_AF2122/97 -------------------------------------------------- Rv3595c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------------------------------------------- MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 AAIHGAITDSTAISGHGGAGNGGNGGKGADGWVQAYDPAGPVGSKIANSS TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 ------------------------------------------YYLVIYQA Mb3543|M.bovis_AF2122/97 ------GSG--TGGKGGAGGDGGDGADG-----------GAATGVGDGGD Rv3595c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK ------GGSGINGGAGGAGGAGGEGGEG-----------GDGGKGGAGAE Mvan_1264|M.vanbaalenii_PYR-1 ------EAVDINGGAGGAGGAGGEGGEG-----------GAGGAGGDGSE MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 AVAGNGGDGGVNGTGGASGGDGGNGGNTSVWKSGGQTADGEHNTGGNGGN TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 IDDIEKALRGMLKPIYEENQLGRAEIRALFRSSKVGIIAGCIISSGVVRR Mb3543|M.bovis_AF2122/97 GGNGGNGGNGGTGVGSPGGLGGAG-------GTGGLGGAGAGGGADGDDG Rv3595c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_5091|M.gilvum_PYR-GCK GGAGGGGGAGGSGAGGAGGAGGSG-------GSGGSGGSGGSGGAAGDSD Mvan_1264|M.vanbaalenii_PYR-1 GGAGGSGGAGGSGTGGAGGAGGSG-------GSGGSGGAGGSGGAAGDSD MMAR_2795|M.marinum_M -------------------------------------------------- MUL_2957|M.ulcerans_Agy99 -------------------------------------------------- MAB_0321c|M.abscessus_ATCC_199 -------------------------------------------------- MSMEG_0868|M.smegmatis_MC2_155 GGDGSEPGPGGNGAGGAGGNGGTGGTTAGGSGNGGNGGNGGNGGADGTPG TH_3810|M.thermoresistible__bu -------------------------------------------------- MAV_2780|M.avium_104 -------------------------------------------------- MLBr_01556|M.leprae_Br4923 NAKVRLLRDNIVVTDNLTVTSLRREKDDVTEVREGFECGMTLGYSDIKEG Mb3543|M.bovis_AF2122/97 DDGQPGNNGS---- Rv3595c|M.tuberculosis_H37Rv -------------- Mflv_5091|M.gilvum_PYR-GCK D------------- Mvan_1264|M.vanbaalenii_PYR-1 -------------- MMAR_2795|M.marinum_M -------------- MUL_2957|M.ulcerans_Agy99 -------------- MAB_0321c|M.abscessus_ATCC_199 -------------- MSMEG_0868|M.smegmatis_MC2_155 TAGTTGANNP---- TH_3810|M.thermoresistible__bu -------------- MAV_2780|M.avium_104 -------------- MLBr_01556|M.leprae_Br4923 DVIESYELVEKQRA