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WAVTRLDPGFFRATVRPSVRLLILDVAYTTQLIGTLVGVRRLYAPSCIAPRGAIYAARVALPHAILVSLS EQAGSGYELAHRFDRSIGHFWTATHQQIYRTLRLMESNGWVHAKPVVQHGRPDKKVYSVSDNGRQELARW IAEPPSPTRPGRASALTDSSTRDIAVKLRGAVYGDRETLRSQVAALRAGRVQALDTYRGIEKHSFPDPSA LSGAALHQYVVLRGGIRAEESAIEWLGEVAQALEEK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_1024 | - | - | 100% (247) | hypothetical protein MUL_1024 |
| M. ulcerans Agy99 | MUL_4945 | - | 1e-18 | 26.84% (190) | hypothetical protein MUL_4945 |
| M. ulcerans Agy99 | MUL_2728 | - | 5e-13 | 30.89% (191) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1209c | - | 5e-84 | 80.32% (188) | hypothetical protein Mb1209c |
| M. gilvum PYR-GCK | Mflv_1331 | - | 3e-09 | 31.37% (102) | PadR-like family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1176c | - | 5e-84 | 80.32% (188) | hypothetical protein Rv1176c |
| M. leprae Br4923 | MLBr_02691 | - | 7e-06 | 23.50% (183) | hypothetical protein MLBr_02691 |
| M. abscessus ATCC 19977 | MAB_1326c | - | 1e-49 | 53.51% (185) | hypothetical protein MAB_1326c |
| M. marinum M | MMAR_4275 | - | 1e-104 | 98.94% (188) | hypothetical protein MMAR_4275 |
| M. avium 104 | MAV_0135 | - | 4e-18 | 31.49% (181) | transcriptional regulator, PadR family protein |
| M. smegmatis MC2 155 | MSMEG_6605 | - | 1e-19 | 29.69% (192) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_5461 | - | 5e-11 | 28.72% (188) | PadR-like family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1331|M.gilvum_PYR-GCK -----------------------------------------------MSI
Mvan_5461|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1209c|M.bovis_AF2122/97 --------------------------------------------------
Rv1176c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_1024|M.ulcerans_Agy99 MWAVTRLDPGFFRATVRPSVRLLILDVAYTTQLIGTLVGVRRLYAPSCIA
MMAR_4275|M.marinum_M --------------------------------------------------
MAB_1326c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0135|M.avium_104 --------------------------------------------------
MSMEG_6605|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_02691|M.leprae_Br4923 --------------------------------------------------
Mflv_1331|M.gilvum_PYR-GCK VECHRYYSSMSLRMAALGLLAQHPASGYDLLKKFEVSMANVWPGTQSQLY
Mvan_5461|M.vanbaalenii_PYR-1 ---------MSLRIAALGLLAEGSASGYDLLKQFEKSMANVWPATQSQLY
Mb1209c|M.bovis_AF2122/97 ---------MALPHAILVSLCEQASSGYELARRFDRSIGYFWTATHQQIY
Rv1176c|M.tuberculosis_H37Rv ---------MALPHAILVSLCEQASSGYELARRFDRSIGYFWTATHQQIY
MUL_1024|M.ulcerans_Agy99 PRGAIYAARVALPHAILVSLSEQAGSGYELAHRFDRSIGHFWTATHQQIY
MMAR_4275|M.marinum_M ---------MALPHAILVSLSEQAGSGYELANRFDRSIGHFWTATHQQIY
MAB_1326c|M.abscessus_ATCC_199 ---------MALTHALLLSLAEQSGSGYELTNRFDRSIGYFYSATHQQIY
MAV_0135|M.avium_104 ---------MSLRDAVLAALLEGESSGYDLAKDFDASVANFWPATPQQLY
MSMEG_6605|M.smegmatis_MC2_155 ---------MALRDAVLAALLEGESSGYDLAKSFDASVANFWTATPQQLY
MLBr_02691|M.leprae_Br4923 ----------MLELAILGLLIESPMHGYELRKRLTGLLGAFRAFSYGSLY
* * * * : **:* . : :. . . : .:*
Mflv_1331|M.gilvum_PYR-GCK SELNKLADDGLIEVTAIGA--RGR---KEYAITRPGRDELRRWVMDFHDD
Mvan_5461|M.vanbaalenii_PYR-1 SELNKLAAGGLIEVCAVGP--RGR---KEYRITDAGRAELQRWVAERQDD
Mb1209c|M.bovis_AF2122/97 RTLRVMENNNWVRATTVLQ--HGRPDKKVYAISDSGRAELARWIAEPLSP
Rv1176c|M.tuberculosis_H37Rv RTLRVMENNNWVRATTVLQ--HGRPDKKVYAISDSGRAELARWIAEPLSP
MUL_1024|M.ulcerans_Agy99 RTLRLMESNGWVHAKPVVQ--HGRPDKKVYSVSDNGRQELARWIAEPPSP
MMAR_4275|M.marinum_M RTLRLMESNGWVHAKPVVQ--HGRPDKKVYSVSDNGRQELARWIAEPPSP
MAB_1326c|M.abscessus_ATCC_199 RTLRRMEDDSWLHCQVVDQ--EGRPAKKVYTVAELGYRELSRWIASS---
MAV_0135|M.avium_104 RELDRLAGQGLIRARVVHQ--QRRPNKRMFSLTAAGRAAIRRFTATAPRP
MSMEG_6605|M.smegmatis_MC2_155 RELERLAADGLIEARVVEQ--ERRPNKRMFSLTDAGRAALREFTAKAPKP
MLBr_02691|M.leprae_Br4923 PALRRMQADRLITGHVAPAGTPVRRARQVYQLTDAGRRRFSELVTDTGPD
* : : * : : :: * : .
Mflv_1331|M.gilvum_PYR-GCK ----------PPQRSSALLRVFLLSAVPSEEAGKYMIAVAEHAERDLARY
Mvan_5461|M.vanbaalenii_PYR-1 ----------PPVRSAGLLRVFLLGLVPPEQARAHLHAMAEEADGEVRRL
Mb1209c|M.bovis_AF2122/97 TRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAERVKSLDTY
Rv1176c|M.tuberculosis_H37Rv TRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAERVKSLDTY
MUL_1024|M.ulcerans_Agy99 TRPGRASALTDSSTRDIAVKLRGAVYGDRETLRSQVAALRAGRVQALDTY
MMAR_4275|M.marinum_M TRPGRASALTDSSTRDIAVKLRGAVYGDRETLRSQVAALRAERVQALDTY
MAB_1326c|M.abscessus_ATCC_199 ---------EGTDMRDLALKVRAATYADSDVVIEQIRAQRNAHAAALEGY
MAV_0135|M.avium_104 ----------SVIRDELLIKVQAADAGDMRAVRDAIRERRDWATAKLARY
MSMEG_6605|M.smegmatis_MC2_155 ----------STIRDELLIKVNAVDAGDAAAVRDAVTEQLRWATEKLARY
MLBr_02691|M.leprae_Br4923 ----------NYTDNGFGVHLAFFNRTPAEARMRILEGRRRRVE---ERR
::: :
Mflv_1331|M.gilvum_PYR-GCK EALRDAVPWNQSDD------DDFYGRAALEFGLRQAAMTADWARWVADGI
Mvan_5461|M.vanbaalenii_PYR-1 TELRESLTGGRAADP---TDESFFGFAALDYGLRLNAMQAEWARSVIDRL
Mb1209c|M.bovis_AF2122/97 RGIEKRTFADPS----ALDGAALHQYLVLRGGIRAEESAIDWLDEVAEAL
Rv1176c|M.tuberculosis_H37Rv RGIEKRTFADPS----ALDGAALHQYLVLRGGIRAEESAIDWLDEVAEAL
MUL_1024|M.ulcerans_Agy99 RGIEKHSFPDPS----ALSGAALHQYVVLRGGIRAEESAIEWLGEVAQAL
MMAR_4275|M.marinum_M RGIEKHSFPDPS----ALSGAALHQYVVLRGGIRAEESAIEWLGEVAQAL
MAB_1326c|M.abscessus_ATCC_199 LHMQKRQFPAPD----QLSGAALHQYLVLRGGIRMEEGFTDWCDEMLSAL
MAV_0135|M.avium_104 QRLRARLLDGRSEEDYLARAERIGPYLTLIRGISFEEDNIRWAEHALAVI
MSMEG_6605|M.smegmatis_MC2_155 ERMRIRMLAGRSEDEFVAGTDRIGPYLTLLRGISFEQENVRWAEQALDLL
MLBr_02691|M.leprae_Br4923 EGLREAVTRASN-------SFDRYTRQLHQLGLESSEREVKWLNELIAAE
:. *: *
Mflv_1331|M.gilvum_PYR-GCK RARQK--------------------
Mvan_5461|M.vanbaalenii_PYR-1 DT-----------------------
Mb1209c|M.bovis_AF2122/97 QEKR---------------------
Rv1176c|M.tuberculosis_H37Rv QEKR---------------------
MUL_1024|M.ulcerans_Agy99 EEK----------------------
MMAR_4275|M.marinum_M EEK----------------------
MAB_1326c|M.abscessus_ATCC_199 SSSHVPARTDESEIDE---------
MAV_0135|M.avium_104 ARRLPTTDADSDAGDSRLVGPATNG
MSMEG_6605|M.smegmatis_MC2_155 RRRMDP------GRQGRMLRSVRRT
MLBr_02691|M.leprae_Br4923 RALLGRVEQT---------------