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MNSALVALAFAAGSVAALNPCGFAMLPAYLLLVVRGQHGGESGEAASPIGAVGRAIAATIGMALGFLTVF GAFGALTISAASTVQRYLPYLTVSIGVLLFGLGVWLLSGRELAALTPSGFGPRWAPTARLGSMYGYGVSY AVASLSCTIGPFIAVTGAGLRGGSILGAVAIYLAYIAGLTMVVGALAIAAATASSALADRLRRVLPLVNR ISGGLLAVVGLYVGYYGYYEVRLTSGLLVDPQDRVIGAAGRIQGELAGWVHQHGIWPWVVVLTLLVAGAF SVSWYRRARR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2080 | - | - | 100% (290) | integral membrane protein |
| M. ulcerans Agy99 | MUL_0626 | ccsA | 9e-10 | 29.79% (235) | cytochrome C-type biogenesis protein, CcsA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2902c | - | 1e-123 | 74.48% (290) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_3217 | - | 3e-25 | 27.62% (286) | cytochrome c biogenesis protein, transmembrane region |
| M. tuberculosis H37Rv | Rv2877c | - | 1e-122 | 74.48% (290) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3244 | - | 1e-69 | 53.12% (256) | mercuric transporter MerT |
| M. marinum M | MMAR_1832 | - | 1e-159 | 97.93% (290) | integral membrane protein |
| M. avium 104 | MAV_3728 | - | 1e-106 | 67.24% (290) | cytochrome C biogenesis protein transmembrane region |
| M. smegmatis MC2 155 | MSMEG_3541 | - | 4e-93 | 62.41% (274) | cytochrome C biogenesis protein transmembrane region |
| M. thermoresistible (build 8) | TH_3805 | - | 7e-60 | 58.45% (207) | PUTATIVE putative NADH-quinone oxidoreductase, L subunit |
| M. vanbaalenii PYR-1 | Mvan_3693 | - | 2e-08 | 25.45% (224) | cytochrome c biogenesis protein, transmembrane region |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_2080|M.ulcerans_Agy99 -----------MNSALVALAFAAGSVAALNPCGFAMLPAYLLLVVRGQHG
MMAR_1832|M.marinum_M -----------MNSALVALAFAAGSVAALNPCGFAMLPAYLLLVVRGQHG
Mb2902c|M.bovis_AF2122/97 -----------MNEALIGLAFAAGLVAALNPCGFAMLPAYLLLVVHGQDS
Rv2877c|M.tuberculosis_H37Rv -----------MNEALIGLAFAAGLVAALNPCGFAMLPAYLLLVVYGQDS
MAV_3728|M.avium_104 -----------MDRGLVGLAVAAGMVAALNPCGFAMLPAYLLLVVRG---
TH_3805|M.thermoresistible__bu --------------------------------------------------
MAB_3244|M.abscessus_ATCC_1997 -------------------------------------------MVRG---
MSMEG_3541|M.smegmatis_MC2_155 -----------MEQDLLGLAFGAGLVAALNPCGFALLPGYLALVVRG---
Mflv_3217|M.gilvum_PYR-GCK -------------MNLLALAFTAGMLAPVNPCGFALLPAWITGTIAT---
Mvan_3693|M.vanbaalenii_PYR-1 MDGVTAIATSGHVLLAVFVSALAGLVSFASPCVVPLVPGYLSYLAAVVGV
MUL_2080|M.ulcerans_Agy99 GESGEAASPIGAVGRAIAATIGMALGFLTVFGAFGALTISAASTVQRYLP
MMAR_1832|M.marinum_M GESGEVGSPIGAVGRAIAATIGMALGFLTVFGAFGALTISAASTVQRYLP
Mb2902c|M.bovis_AF2122/97 --AGRTG-PLSAVGRAAAATVGMALGFLTVFGIFGALTISAATAVQRYLP
Rv2877c|M.tuberculosis_H37Rv --AGRTG-PLSAVGRAAAATVGMALGFLTVFGIFGALTISAATAVQRYLP
MAV_3728|M.avium_104 --AGARAPGVAAAGRALAASAGMALGFLTVFGLFGALTVSAAGAVQRWLP
TH_3805|M.thermoresistible__bu --------------------------------------------VQRYLP
MAB_3244|M.abscessus_ATCC_1997 --PGAEIGKSQALARAVIATVVMAGGFVAVFTVFGLLTVSVASVIQRYLP
MSMEG_3541|M.smegmatis_MC2_155 --ENAATG-ARALGRAALATVAMAAGFVAVFGTFTALTVATASTVQRYLP
Mflv_3217|M.gilvum_PYR-GCK ---GGTDAVLVRLARALRTGAVLTIGFTGTLTLAGIAISAGARTLVTAAP
Mvan_3693|M.vanbaalenii_PYR-1 DDQARAQPLGRARLRLAGAAGLFVAGFTAVFLMGTVAILGLTTTLITNGV
:
MUL_2080|M.ulcerans_Agy99 YLTVSIGVLLFGLG----VWLLSGRELAALTPSGFGPR--WAPTARLGSM
MMAR_1832|M.marinum_M YLTVLIGVLLFGLG----VWLLSGRELAALTPSGFGPR--WAPTARLGSM
Mb2902c|M.bovis_AF2122/97 YATVLIGLALIALG----GWLLLGRGLTALTPRSLGVR--WAPTVRLGSM
Rv2877c|M.tuberculosis_H37Rv YATVLIGLALIALG----GWLLLGRGLTALTPRSLGVR--WAPTVRLGSM
MAV_3728|M.avium_104 YATVVVGVLLVALG----GWLLAGRSLSALTPRPVGPL--WAPTARLGSM
TH_3805|M.thermoresistible__bu VATVVVGAGLVALG----FWLLIGRELTGLTSVTRRVE--RAPTARIGSM
MAB_3244|M.abscessus_ATCC_1997 FVTVVFGIGLVILG----LWLLAGRDIIALMPKMLDAN---APTTRLGSM
MSMEG_3541|M.smegmatis_MC2_155 YVTVVIGLILVCLG----IWLLAGRRLGVLMPNSLADNPRWAPTARMGSM
Mflv_3217|M.gilvum_PYR-GCK WLGITIGLTLAILG----GFMLTGRTIGLRMPARTRHR---PDSPTAGGV
Mvan_3693|M.vanbaalenii_PYR-1 LLQRIGGVVTIVMGLVFMGFFPALQRDARFTPTSLSTL---WGAPLLGAV
* :* :: : . : *.:
MUL_2080|M.ulcerans_Agy99 YGYGVSYAVASLSCTIGPFIAVTGAGLRGGSILGAVAIYLAYIAGLTMVV
MMAR_1832|M.marinum_M YGYGVSYAVASLSCTIGPFIAVTGAGLRGGSILGAVAIYLAYIAGLTMVV
Mb2902c|M.bovis_AF2122/97 YGYGISYAVASLSCTIGPFLAVTGAGLRGGSVVGSVAIYLAYVAGLTLVV
Rv2877c|M.tuberculosis_H37Rv YGYGISYAVASLSCTIGPFLAVTGAGLRGGSVVGSVAIYLAYVAGLTLVV
MAV_3728|M.avium_104 YGYGISYAIASLSCTVGPFLAVTAAGLRSGSLLTGAAVYLGYVAGLTLVV
TH_3805|M.thermoresistible__bu FGYGVSYAVASLSCTVAPFLAVTGAGLRGQSLWSTLSIYLAYAAGFTLIV
MAB_3244|M.abscessus_ATCC_1997 FGYGVGYAVASLSCTIGPFLAVTSTTFESGSLFDGVMVYLAYASGITLVV
MSMEG_3541|M.smegmatis_MC2_155 LGYGVGYALASLSCTIGPFLAVTGAGLRSGTPLRGVGVFASYAAGFTLVV
Mflv_3217|M.gilvum_PYR-GCK LAAGIGYALASLSCTFGVLLAVIAQAQATSGWGGLLAVFTAYTAGAATIL
Mvan_3693|M.vanbaalenii_PYR-1 FGLGWTPCLG---PTLTGVIAVASASE-GPNVVRGIVLVVAYCVGLGAPF
. * .:. *. .:** . : .* * .
MUL_2080|M.ulcerans_Agy99 GALAIAAATASSALADRLRRVLPLVNRISGGLLAVVGLYVGYYGYYEVRL
MMAR_1832|M.marinum_M GALAIAAATASSALADRLRRVLPLVNRISGGLLVVVGLYVGYYGYYEVRL
Mb2902c|M.bovis_AF2122/97 GVLAVAAATASSALADRLRRILPFVNRISGALLVVVGLYVGYYGLYELRL
Rv2877c|M.tuberculosis_H37Rv GVLAVAAATASSALADRLRRILPFVNRISGALLVVVGLYVGYYGLYELRL
MAV_3728|M.avium_104 GVLAVAAATAGAATADRLRRMVPFVDRISGAVLVLVGLYVAYYGGYEVRL
TH_3805|M.thermoresistible__bu GVLAMAAALTHSALAVRLRRIGRYVNRISGVLLVAVGGYVAYYGLYELRL
MAB_3244|M.abscessus_ATCC_1997 GTLAVSTALASTMLLKAMRRALPYLNRVSGAILIVVGAYVGYYGSYEVRL
MSMEG_3541|M.smegmatis_MC2_155 GVLAVATALARTVVIDRMRRILPYANRISGALLILVGAYVGYYGLYEVRL
Mflv_3217|M.gilvum_PYR-GCK MLVSVGTAIAGTALTRHLGILARHGTRVTAVVLIATGAYLAWYWLPAATG
Mvan_3693|M.vanbaalenii_PYR-1 VLFALASGRAMRALG-WLRRNARRIQVFGGVLLVAVG-------------
.::.:. : : . . :* .*
MUL_2080|M.ulcerans_Agy99 TSGLLVDPQDRVIGAAGRIQGELAGWVHQHGIWPWVVVLTLLVAGAFSVS
MMAR_1832|M.marinum_M TSGLLVDPQDRVIGAAGRIQGELAGWVHQHGIWPWAVALTLLVAGAFSVS
Mb2902c|M.bovis_AF2122/97 IAGVGANPQDAVIAAAGRLQGALAGWVNQHGAWPWAVLLVVLVVGAFAGT
Rv2877c|M.tuberculosis_H37Rv IAGVGANPQDAVIAAAGRLQGALAGWVNQHGAWPWAVLLVVLVVGAFAGT
MAV_3728|M.avium_104 FG-AGGDPRDAVIGAAGRLQGALAGWVHRHGLWPWALALLALAAVRFGRA
TH_3805|M.thermoresistible__bu FW-GGANPQDPVIEAAARAQGAIAGWVHRHGGGPWLAATAVLMLVVLATG
MAB_3244|M.abscessus_ATCC_1997 FH-ANGNPDDPIINAAGKIQRTISGWVYLHGAWPWLFILGLVAVGAAIWW
MSMEG_3541|M.smegmatis_MC2_155 FS-GSGDPHDPVIAAAGKIQGTLAGWVHQHGALPWAIGL-LVLIGLGLLW
Mflv_3217|M.gilvum_PYR-GCK HTASGGN-------LLTGWSATATGWLQDHALPASVIAAFAVVVSAVAAY
Mvan_3693|M.vanbaalenii_PYR-1 ------------IALVTGLWNEVVSWVRDAFVSNTTLPI-----------
.*:
MUL_2080|M.ulcerans_Agy99 WYR--RARR-----------------------------------------
MMAR_1832|M.marinum_M WYR--RARR-----------------------------------------
Mb2902c|M.bovis_AF2122/97 WFR--RVRR-----------------------------------------
Rv2877c|M.tuberculosis_H37Rv WFR--RVRR-----------------------------------------
MAV_3728|M.avium_104 RRRGRRADRLPDPAAAAAPQVADQHHEDQRRESDQKPVLDVADVVAAQHG
TH_3805|M.thermoresistible__bu FVA--RIRRSARR-------------------------------------
MAB_3244|M.abscessus_ATCC_1997 RTNVSEPPSN----------------------------------------
MSMEG_3541|M.smegmatis_MC2_155 RVRIFARRSPARRATADDAP------------------------------
Mflv_3217|M.gilvum_PYR-GCK WTTHRRPITGKQRRR-----------------------------------
Mvan_3693|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2080|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1832|M.marinum_M --------------------------------------------------
Mb2902c|M.bovis_AF2122/97 --------------------------------------------------
Rv2877c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_3728|M.avium_104 QQQPEDDQADDVPGPVVDPAPSPRRRRHLDGVDAGEVLDLGTGHGESPSD
TH_3805|M.thermoresistible__bu --------------------------------------------------
MAB_3244|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3541|M.smegmatis_MC2_155 --------------------------------------------------
Mflv_3217|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_3693|M.vanbaalenii_PYR-1 --------------------------------------------------
MUL_2080|M.ulcerans_Agy99 --------------------------------
MMAR_1832|M.marinum_M --------------------------------
Mb2902c|M.bovis_AF2122/97 --------------------------------
Rv2877c|M.tuberculosis_H37Rv --------------------------------
MAV_3728|M.avium_104 RIGLSNPDSGTTAGRARGARPHHGPRRWRAAQ
TH_3805|M.thermoresistible__bu --------------------------------
MAB_3244|M.abscessus_ATCC_1997 --------------------------------
MSMEG_3541|M.smegmatis_MC2_155 --------------------------------
Mflv_3217|M.gilvum_PYR-GCK --------------------------------
Mvan_3693|M.vanbaalenii_PYR-1 --------------------------------