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EQDLLGLAFGAGLVAALNPCGFALLPGYLALVVRGENAATGARALGRAALATVAMAAGFVAVFGTFTALT VATASTVQRYLPYVTVVIGLILVCLGIWLLAGRRLGVLMPNSLADNPRWAPTARMGSMLGYGVGYALASL SCTIGPFLAVTGAGLRSGTPLRGVGVFASYAAGFTLVVGVLAVATALARTVVIDRMRRILPYANRISGAL LILVGAYVGYYGLYEVRLFSGSGDPHDPVIAAAGKIQGTLAGWVHQHGALPWAIGLLVLIGLGLLWRVRI FARRSPARRATADDAP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_3541 | - | - | 100% (297) | cytochrome C biogenesis protein transmembrane region |
| M. smegmatis MC2 155 | MSMEG_0972 | - | 1e-09 | 30.77% (234) | cytochrome C biogenesis protein transmembrane region |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2902c | - | 2e-97 | 65.45% (275) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_3217 | - | 1e-30 | 32.71% (266) | cytochrome c biogenesis protein, transmembrane region |
| M. tuberculosis H37Rv | Rv2877c | - | 3e-97 | 65.45% (275) | integral membrane protein |
| M. leprae Br4923 | MLBr_02411 | - | 5e-08 | 28.69% (237) | putative cytochrome C-type biogenesis protein |
| M. abscessus ATCC 19977 | MAB_3244 | - | 2e-81 | 61.75% (251) | mercuric transporter MerT |
| M. marinum M | MMAR_1832 | - | 4e-94 | 62.04% (274) | integral membrane protein |
| M. avium 104 | MAV_3728 | - | 2e-95 | 60.96% (292) | cytochrome C biogenesis protein transmembrane region |
| M. thermoresistible (build 8) | TH_3805 | - | 6e-62 | 57.08% (212) | PUTATIVE putative NADH-quinone oxidoreductase, L subunit |
| M. ulcerans Agy99 | MUL_2080 | - | 3e-93 | 62.41% (274) | integral membrane protein |
| M. vanbaalenii PYR-1 | Mvan_0867 | - | 3e-10 | 29.91% (234) | cytochrome c biogenesis protein, transmembrane region |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2902c|M.bovis_AF2122/97 MNEALIGLAFAAGLVAALNPCGFAMLPAYLLLVVHGQDS--AGRTG-PLS
Rv2877c|M.tuberculosis_H37Rv MNEALIGLAFAAGLVAALNPCGFAMLPAYLLLVVYGQDS--AGRTG-PLS
MMAR_1832|M.marinum_M MNSALVALAFAAGSVAALNPCGFAMLPAYLLLVVRGQHGGESGEVGSPIG
MUL_2080|M.ulcerans_Agy99 MNSALVALAFAAGSVAALNPCGFAMLPAYLLLVVRGQHGGESGEAASPIG
MAV_3728|M.avium_104 MDRGLVGLAVAAGMVAALNPCGFAMLPAYLLLVVRG-----AGARAPGVA
TH_3805|M.thermoresistible__bu --------------------------------------------------
MSMEG_3541|M.smegmatis_MC2_155 MEQDLLGLAFGAGLVAALNPCGFALLPGYLALVVRG-----ENAATG-AR
MAB_3244|M.abscessus_ATCC_1997 --------------------------------MVRG-----PGAEIGKSQ
MLBr_02411|M.leprae_Br4923 -----------------------------------------------MTG
Mvan_0867|M.vanbaalenii_PYR-1 ---------------------------------------------MTLDQ
Mflv_3217|M.gilvum_PYR-GCK --MNLLALAFTAGMLAPVNPCGFALLPAWITGTIAT------GGTDAVLV
Mb2902c|M.bovis_AF2122/97 AVGRAAAATVGMALGFLTVFGIFGALTISAATAVQRYLPYATVLIGLALI
Rv2877c|M.tuberculosis_H37Rv AVGRAAAATVGMALGFLTVFGIFGALTISAATAVQRYLPYATVLIGLALI
MMAR_1832|M.marinum_M AVGRAIAATIGMALGFLTVFGAFGALTISAASTVQRYLPYLTVLIGVLLF
MUL_2080|M.ulcerans_Agy99 AVGRAIAATIGMALGFLTVFGAFGALTISAASTVQRYLPYLTVSIGVLLF
MAV_3728|M.avium_104 AAGRALAASAGMALGFLTVFGLFGALTVSAAGAVQRWLPYATVVVGVLLV
TH_3805|M.thermoresistible__bu ---------------------------------VQRYLPVATVVVGAGLV
MSMEG_3541|M.smegmatis_MC2_155 ALGRAALATVAMAAGFVAVFGTFTALTVATASTVQRYLPYVTVVIGLILV
MAB_3244|M.abscessus_ATCC_1997 ALARAVIATVVMAGGFVAVFTVFGLLTVSVASVIQRYLPFVTVVFGIGLV
MLBr_02411|M.leprae_Br4923 FTEIAAAGPLLVALGVCMLAGLVSFVSPCVVPLVPGYLSYLAAVVGVSHE
Mvan_0867|M.vanbaalenii_PYR-1 IDQLTATGPLLLATGLAALAGLVSFASPCVIPLVPGYLSYLAAVVGVDQS
Mflv_3217|M.gilvum_PYR-GCK RLARALRTGAVLTIGFTGTLTLAGIAISAGARTLVTAAPWLGITIGLTLA
: . .*
Mb2902c|M.bovis_AF2122/97 ALGGWLLLGRGLTALTPRSLGVR--WAPTVRLGSMYGYGISYAVASLSCT
Rv2877c|M.tuberculosis_H37Rv ALGGWLLLGRGLTALTPRSLGVR--WAPTVRLGSMYGYGISYAVASLSCT
MMAR_1832|M.marinum_M GLGVWLLSGRELAALTPSGFGPR--WAPTARLGSMYGYGVSYAVASLSCT
MUL_2080|M.ulcerans_Agy99 GLGVWLLSGRELAALTPSGFGPR--WAPTARLGSMYGYGVSYAVASLSCT
MAV_3728|M.avium_104 ALGGWLLAGRSLSALTPRPVGPL--WAPTARLGSMYGYGISYAIASLSCT
TH_3805|M.thermoresistible__bu ALGFWLLIGRELTGLTSVTRRVE--RAPTARIGSMFGYGVSYAVASLSCT
MSMEG_3541|M.smegmatis_MC2_155 CLGIWLLAGRRLGVLMPNSLADNPRWAPTARMGSMLGYGVGYALASLSCT
MAB_3244|M.abscessus_ATCC_1997 ILGLWLLAGRDIIALMPKMLDAN---APTTRLGSMFGYGVGYAVASLSCT
MLBr_02411|M.leprae_Br4923 ETQPGAGVIKTPPAARWRVAGSAVLFVAGFTTVFVLDTVAVLGMTTVLTT
Mvan_0867|M.vanbaalenii_PYR-1 AAGSAAPGAVAVKGARLRVAGAAGLFVAGFTVVFLLGTVAVLGMTTALIT
Mflv_3217|M.gilvum_PYR-GCK ILGGFMLTGRTIGLRMPARTRHR---PDSPTAGGVLAAGIGYALASLSCT
: .::: *
Mb2902c|M.bovis_AF2122/97 IGPFLAVTGAGLRGGSVVGSVAIYLAYVAGLTLVVGVLAVAAATASSALA
Rv2877c|M.tuberculosis_H37Rv IGPFLAVTGAGLRGGSVVGSVAIYLAYVAGLTLVVGVLAVAAATASSALA
MMAR_1832|M.marinum_M IGPFIAVTGAGLRGGSILGAVAIYLAYIAGLTMVVGALAIAAATASSALA
MUL_2080|M.ulcerans_Agy99 IGPFIAVTGAGLRGGSILGAVAIYLAYIAGLTMVVGALAIAAATASSALA
MAV_3728|M.avium_104 VGPFLAVTAAGLRSGSLLTGAAVYLGYVAGLTLVVGVLAVAAATAGAATA
TH_3805|M.thermoresistible__bu VAPFLAVTGAGLRGQSLWSTLSIYLAYAAGFTLIVGVLAMAAALTHSALA
MSMEG_3541|M.smegmatis_MC2_155 IGPFLAVTGAGLRSGTPLRGVGVFASYAAGFTLVVGVLAVATALARTVVI
MAB_3244|M.abscessus_ATCC_1997 IGPFLAVTSTTFESGSLFDGVMVYLAYASGITLVVGTLAVSTALASTMLL
MLBr_02411|M.leprae_Br4923 HQVLLQRVGGVLTIVMGLVFVGLLPALQRQVQFSLRQLTTVAGAPVLGTV
Mvan_0867|M.vanbaalenii_PYR-1 NQLLLQRLGGVVTILMGLVFIGLVPVLQRDTRFTPRQISTLGGAPLLGAV
Mflv_3217|M.gilvum_PYR-GCK FGVLLAVIAQAQATSGWGGLLAVFTAYTAGAATILMLVSVGTAIAGTALT
:: . : :: . .
Mb2902c|M.bovis_AF2122/97 DRLRRILPFVNRISGALLVVVGLYVGYYGLYELRLIAGVGANPQDAVIAA
Rv2877c|M.tuberculosis_H37Rv DRLRRILPFVNRISGALLVVVGLYVGYYGLYELRLIAGVGANPQDAVIAA
MMAR_1832|M.marinum_M DRLRRVLPLVNRISGGLLVVVGLYVGYYGYYEVRLTSGLLVDPQDRVIGA
MUL_2080|M.ulcerans_Agy99 DRLRRVLPLVNRISGGLLAVVGLYVGYYGYYEVRLTSGLLVDPQDRVIGA
MAV_3728|M.avium_104 DRLRRMVPFVDRISGAVLVLVGLYVAYYGGYEVRLFG-AGGDPRDAVIGA
TH_3805|M.thermoresistible__bu VRLRRIGRYVNRISGVLLVAVGGYVAYYGLYELRLFW-GGANPQDPVIEA
MSMEG_3541|M.smegmatis_MC2_155 DRMRRILPYANRISGALLILVGAYVGYYGLYEVRLFS-GSGDPHDPVIAA
MAB_3244|M.abscessus_ATCC_1997 KAMRRALPYLNRVSGAILIVVGAYVGYYGSYEVRLFH-ANGNPDDPIINA
MLBr_02411|M.leprae_Br4923 FALGWTPCLGPTLSGVITVAAATDGVNVTRGILLVIAYCMGLGIPFVLLA
Mvan_0867|M.vanbaalenii_PYR-1 FALGWTPCLGPTLTGVIAVASATEGSNVARGVVLVIAYCLGLGIPFVLLA
Mflv_3217|M.gilvum_PYR-GCK RHLGILARHGTRVTAVVLIATGAYLAWYWLPAATGHTASGGN-------L
: ::. : .
Mb2902c|M.bovis_AF2122/97 AGRLQGALAG-WVNQHGAWPWAVLLVVLVVGAFAGTWFR--RVRR-----
Rv2877c|M.tuberculosis_H37Rv AGRLQGALAG-WVNQHGAWPWAVLLVVLVVGAFAGTWFR--RVRR-----
MMAR_1832|M.marinum_M AGRIQGELAG-WVHQHGIWPWAVALTLLVAGAFSVSWYR--RARR-----
MUL_2080|M.ulcerans_Agy99 AGRIQGELAG-WVHQHGIWPWVVVLTLLVAGAFSVSWYR--RARR-----
MAV_3728|M.avium_104 AGRLQGALAG-WVHRHGLWPWALALLALAAVRFGRARRRGRRADRLPDPA
TH_3805|M.thermoresistible__bu AARAQGAIAG-WVHRHGGGPWLAATAVLMLVVLATGFVA--RIRRSARR-
MSMEG_3541|M.smegmatis_MC2_155 AGKIQGTLAG-WVHQHGALPWAIGL--LVLIGLGLLWRVRIFARRSPARR
MAB_3244|M.abscessus_ATCC_1997 AGKIQRTISG-WVYLHGAWPWLFILG-LVAVGAAIWWRTNVSEPPSN---
MLBr_02411|M.leprae_Br4923 SGSAQAVAGLRWLRQYGRAIQVFGGMLLIAIGAALIAGVWDDFVSWLRDA
Mvan_0867|M.vanbaalenii_PYR-1 FGSARAVAGLGWLRRHTRTIQVLGGVLMILVGAALVTGLWNDFVSWIRDA
Mflv_3217|M.gilvum_PYR-GCK LTGWSATATG-WLQDHALPASVIAAFAVVVSAVAAYWTTHRRPITGKQRR
*: : : .
Mb2902c|M.bovis_AF2122/97 --------------------------------------------------
Rv2877c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1832|M.marinum_M --------------------------------------------------
MUL_2080|M.ulcerans_Agy99 --------------------------------------------------
MAV_3728|M.avium_104 AAAAPQVADQHHEDQRRESDQKPVLDVADVVAAQHGQQQPEDDQADDVPG
TH_3805|M.thermoresistible__bu --------------------------------------------------
MSMEG_3541|M.smegmatis_MC2_155 ATADDAP-------------------------------------------
MAB_3244|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02411|M.leprae_Br4923 VVSDMRVSI-----------------------------------------
Mvan_0867|M.vanbaalenii_PYR-1 FVSDVRLPI-----------------------------------------
Mflv_3217|M.gilvum_PYR-GCK R-------------------------------------------------
Mb2902c|M.bovis_AF2122/97 --------------------------------------------------
Rv2877c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1832|M.marinum_M --------------------------------------------------
MUL_2080|M.ulcerans_Agy99 --------------------------------------------------
MAV_3728|M.avium_104 PVVDPAPSPRRRRHLDGVDAGEVLDLGTGHGESPSDRIGLSNPDSGTTAG
TH_3805|M.thermoresistible__bu --------------------------------------------------
MSMEG_3541|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3244|M.abscessus_ATCC_1997 --------------------------------------------------
MLBr_02411|M.leprae_Br4923 --------------------------------------------------
Mvan_0867|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3217|M.gilvum_PYR-GCK --------------------------------------------------
Mb2902c|M.bovis_AF2122/97 ------------------
Rv2877c|M.tuberculosis_H37Rv ------------------
MMAR_1832|M.marinum_M ------------------
MUL_2080|M.ulcerans_Agy99 ------------------
MAV_3728|M.avium_104 RARGARPHHGPRRWRAAQ
TH_3805|M.thermoresistible__bu ------------------
MSMEG_3541|M.smegmatis_MC2_155 ------------------
MAB_3244|M.abscessus_ATCC_1997 ------------------
MLBr_02411|M.leprae_Br4923 ------------------
Mvan_0867|M.vanbaalenii_PYR-1 ------------------
Mflv_3217|M.gilvum_PYR-GCK ------------------