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TTPEFAARPQLAEDVARFVRRRIFDGTYPAGRYIRLEQLAAELGISVTPVREALFGLRAEGLLTQQPRRG FVVSPITERDIADVSDVQAHIGGVLASRAAELITDEQLAELERIQDELEAAYDAVDHEAAVRLNHAFHRG VNIAAGSPKLAQLMGQITRFALESVYPTVEGWPAHSMNDHRVLLAALRKRDGTAARDAMSEHLCAAAGPL IDHLTTRGVIG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4366 | - | - | 100% (222) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_0715 | - | 8e-30 | 37.50% (184) | regulatory protein GntR, HTH |
| M. gilvum PYR-GCK | Mflv_0859 | - | 5e-11 | 25.47% (212) | regulatory protein GntR, HTH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 4e-35 | 39.72% (214) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0165c | - | 1e-27 | 43.14% (153) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4571 | - | 3e-30 | 35.38% (212) | GntR family transcriptional regulatory protein |
| M. marinum M | MMAR_4029 | - | 9e-81 | 66.52% (221) | GntR family transcriptional regulator |
| M. avium 104 | MAV_1576 | - | 1e-84 | 67.87% (221) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_2209 | - | 1e-92 | 76.92% (221) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3342 | - | 3e-86 | 70.59% (221) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3894 | - | 3e-80 | 66.06% (221) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1978 | - | 1e-105 | 85.52% (221) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4366|M.gilvum_PYR-GCK -------------------------------------------------M
Mvan_1978|M.vanbaalenii_PYR-1 -------------------------------------------------M
MSMEG_2209|M.smegmatis_MC2_155 -------------------------------------------------M
MMAR_4029|M.marinum_M -------------------------------------------------M
MUL_3894|M.ulcerans_Agy99 -------------------------------------------------M
MAV_1576|M.avium_104 -------------------------------------------------M
TH_3342|M.thermoresistible__bu -------------------------------------------------V
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
MAB_4571|M.abscessus_ATCC_1997 -----------------------------------------MNAPR-ART
Mflv_4366|M.gilvum_PYR-GCK TTPEFAARPQLAEDVARFVRRRIFDGTYPAGRYIRLEQLAAELGISVTPV
Mvan_1978|M.vanbaalenii_PYR-1 SIPEFAARPQLAEDVARFVRRRIFEGTYPAGQYIRLEQLADELGISVTPV
MSMEG_2209|M.smegmatis_MC2_155 TVPDFAARPQLAEDVARLIRRRIFDGTYPAGKYIRLDQLAAELGISVTPV
MMAR_4029|M.marinum_M TDPEFAARPQLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
MUL_3894|M.ulcerans_Agy99 TDPEFAARPQLSDDVARYVRKRIYEGNYAAGKYIRLDQLAAELGISVTPV
MAV_1576|M.avium_104 SVPDFAARPQLSDDVAHLIRGRIFDGSYAAGSYVRLDQLAAELGISVTPV
TH_3342|M.thermoresistible__bu AVPEFAARPQLAEDVARYVRRRIFDGTYAAGEYVRLDQLAVELGVSVTPV
Mb0170c|M.bovis_AF2122/97 RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Rv0165c|M.tuberculosis_H37Rv RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
MAB_4571|M.abscessus_ATCC_1997 R---EIRRPQLSEEVAGRLRAAIMTGDLRPGEYIRMDETAAQLGVSVTPV
*.**:::** :* * * .* ::*::: * :**:*****
Mflv_4366|M.gilvum_PYR-GCK REALFGLRAEGLLTQQPRRGFVVSPITERDIADVSDVQAHIGGVLASRAA
Mvan_1978|M.vanbaalenii_PYR-1 REALFGLRAEGLLTQQPRRGFVVLPITRRDIADVADVQAHIGGVLASRAA
MSMEG_2209|M.smegmatis_MC2_155 REALFGLRTEGLLAQQPRRGFIVLPVTRRDIDDVAGVQAHIGGQLAARAA
MMAR_4029|M.marinum_M REALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAARAA
MUL_3894|M.ulcerans_Agy99 REALFALRAEGLVAQQPHRGFVVLPLTKRDLADVAYVQAHVGGELAARAA
MAV_1576|M.avium_104 REALFALRAEGLISQQPRRGFVVLPVTRRDVTDVANVQAHVGGELAARAA
TH_3342|M.thermoresistible__bu REALFQLRAEGLLVQQPRRGFMVLPVTERDLTDIANVQAHVGGELAARAA
Mb0170c|M.bovis_AF2122/97 REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Rv0165c|M.tuberculosis_H37Rv REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
MAB_4571|M.abscessus_ATCC_1997 REALLTLRGEGMVDAVPHRGYAVAALSRKDVEDIFALQSHLAVELAKAAA
****: ** **:: *:**. * .::.:*: *: :*: :. ** *:
Mflv_4366|M.gilvum_PYR-GCK ELITDEQLAELERIQDELEAAYDAVDHEAAVRLNHAFHRGVNIAAGSPKL
Mvan_1978|M.vanbaalenii_PYR-1 ERITDEQLQALDHVQDQLEVAYHADDHEAAVRLNHEFHRGVNVAAGSPKL
MSMEG_2209|M.smegmatis_MC2_155 GQITDAQLEELGRIQDELEQAYARDDHEAAVRLNHAFHRGVNRAAESPKL
MMAR_4029|M.marinum_M INIGAAQLAELQQIQAQLEEAYAADDDERTVRLNHEFHRAINLAADSPRL
MUL_3894|M.ulcerans_Agy99 INIGAAQLAELQQIQAQLEEAYAADDDERTVRLNHEFHRAINLAADSPRL
MAV_1576|M.avium_104 VNITDDQLRELKQIQAQLEDAYAGDEHERTVRLNHEFHRAINIAADSPKL
TH_3342|M.thermoresistible__bu QNITDEQLRVLTAIQDELEEAYTRDDEDRAVRLNHEFHRAINVAADSPKL
Mb0170c|M.bovis_AF2122/97 AHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIKL
Rv0165c|M.tuberculosis_H37Rv AHITDVEIDELDRINNALAGAIGSGDAKTIASIEFAFHRVFNKASRRIKL
MAB_4571|M.abscessus_ATCC_1997 ARITPEQADALAELNDALRNATSP---DQVIWAEFEFHRLLNHVADRPKL
* : * :: * * . :. *** .* .: :*
Mflv_4366|M.gilvum_PYR-GCK AQLMGQITRFALESVYPTVEGWPAHSMNDHRVLLAALRKRDGTAARDAMS
Mvan_1978|M.vanbaalenii_PYR-1 AQLMGQITKFALESVYPTVEGWPAHSTRDHRELLAALKARDSEAARAAMS
MSMEG_2209|M.smegmatis_MC2_155 AQLMSQITRYALESVYPTVEGWPEQSTHDHRRILDALGRHDGELARAAMA
MMAR_4029|M.marinum_M SQLMSQITRYQPESVFPGIEHWPARAVKDHRRVLVALKKHDDKAARTAMS
MUL_3894|M.ulcerans_Agy99 SQLMSQITRYQPESVFPGIEHWPARAVKDHGQVLVALKKHDDKAARTAMS
MAV_1576|M.avium_104 AQLMSQITRYAPESVFPAIQGWPEQSMKDHRRILSALKKRDDKLARAAMS
TH_3342|M.thermoresistible__bu AQVMSQITRYAPESVFPTISGWPARSTEHHRRVLAALADRDPDGARAAMS
Mb0170c|M.bovis_AF2122/97 AWFLLNAARYMPAQVFAADPRWGADAVNSHRQLIAALRRRDTAAVIEHTV
Rv0165c|M.tuberculosis_H37Rv AWFLLNAARYMGAGVRGRP----AMGRGRGEQSSAADRR---AAPPRHSR
MAB_4571|M.abscessus_ATCC_1997 AWFLLQAVRYTPHQLFAEDASWIVPTTETHDKLIAALRAGDIAEVIAQTE
: .: : .:: : *
Mflv_4366|M.gilvum_PYR-GCK EHLCAAAGPLIDHLTTRGVIG---------------
Mvan_1978|M.vanbaalenii_PYR-1 EHLCAASGPLIEHLTRRGVIQ---------------
MSMEG_2209|M.smegmatis_MC2_155 DHLCAASKPLIDHLARLGVLE---------------
MMAR_4029|M.marinum_M EHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG
MUL_3894|M.ulcerans_Agy99 EHLASSAVPLIDHLIARGVVAESAPSGSAAERARGG
MAV_1576|M.avium_104 EHLAAGAVPLIDHLVARGVVVD----GGGPDPG---
TH_3342|M.thermoresistible__bu EHLAAGAGPLIEHLKEHGVIAQ--------------
Mb0170c|M.bovis_AF2122/97 WQFTDGARRLTEALAETEVFG---------------
Rv0165c|M.tuberculosis_H37Rv R---NRAHRLAVHRWGTQADGGPG------------
MAB_4571|M.abscessus_ATCC_1997 VQFIDGARRLIEYLDRTGMWSQD-------------
: *