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QIGRRELVAVIIAILLVTAAFVVPHLDLGIVTPLINSTPAQIYSFADTAPIFGWWNAHVGWGTVPAVLIG AATVWWGPAVAQRLPWRALPLVAWVTSALWAFSLAMIDGWQRGFAGRLTARHEYLRQVPSVTDIGEALRT FSSRILDFQPDSWITHVSGHPPGALLTFVWLDRIGLGGGAWAGLLCLLVGSSAAAAIVVALRAVSGEATA RLAAPFVAVAPTAIWIAVSADGYFAGVAAWGLALLALAVRDSVHRRRVALPTAVGSGLLLGWGIFLNYGL ALAALIALAVLITAPDWRAALRVAVPAVIAVLAVVAVFLVAGFWWFDGYTLVQERYWQGIANNRPFQYWS WANLASVVCAIGLGSVAGIGRVFDIKAARRNPGLPMLVIGALLAITFADLSMLSKAETERIWLPFTVWLT AAGALLPPRSHRWWLGLNVAGALALNHLILTNW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0999 | - | - | 100% (454) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0555c | - | 1e-178 | 68.06% (454) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_0468 | - | 2e-05 | 24.91% (285) | hypothetical protein Mflv_0468 |
| M. tuberculosis H37Rv | Rv0541c | - | 1e-178 | 68.28% (454) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0887 | - | 1e-174 | 66.30% (454) | hypothetical protein MMAR_0887 |
| M. avium 104 | MAV_4603 | - | 1e-173 | 66.15% (455) | integral membrane protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0640 | - | 1e-172 | 65.64% (454) | hypothetical protein MUL_0640 |
| M. vanbaalenii PYR-1 | Mvan_0891 | - | 0.0 | 77.65% (452) | putative integral membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0999|M.smegmatis_MC2_155 ----------MQIGRRELVAVIIAILLVTAAFVVPHLDLGIVTPLINSTP
Mvan_0891|M.vanbaalenii_PYR-1 ----------MPIGRKEAVAVAVGSVLVVAAFVIPHLDLGVVTPLINATP
Mb0555c|M.bovis_AF2122/97 ----------MRIGRREGLAVAIGFVLVGAAFVLPRLNLGIK-PRSDIGL
Rv0541c|M.tuberculosis_H37Rv ----------MRIGRREGLAVAIGFVLVGAAFVLPRLNLGIK-PRSDIGL
MAV_4603|M.avium_104 ------------------MAAAVGAALVAAAFLLPRLNLGVR-PRLDVGP
MMAR_0887|M.marinum_M ----------MRIARRETAAVTVGVVLVAAAFVLPRLDLGVK-PRRDIGL
MUL_0640|M.ulcerans_Agy99 ----------MRIARRETAAVTVGVVLVAAAFVLPRLDLGVK-PRRDIGL
Mflv_0468|M.gilvum_PYR-GCK MLRGDGPGPARQWSADAVVVGVLAFALGVAAAGRPSLWVDEAGTLSAATR
. :. * ** * * :. .
MSMEG_0999|M.smegmatis_MC2_155 ---AQIYSFADTAPIFGWWNAHVG-----------WGTVPAVLIGAATVW
Mvan_0891|M.vanbaalenii_PYR-1 ---ERLRSFADTAPIFGWWNTHVG-----------AGTIPAFAIGAAAVL
Mb0555c|M.bovis_AF2122/97 ---ERFATRAGAAPIFGYWDAHVG-----------WGTAPAVLTAVAVVA
Rv0541c|M.tuberculosis_H37Rv ---ERFATRAGAAPIFGYWDAHVG-----------WGTAPAVLTAVAVVA
MAV_4603|M.avium_104 ---ERFATHAGAAPIFGEWLIHAG-----------WGTGPAVALAAAVVA
MMAR_0887|M.marinum_M ---ERFASRAGAAPIFGYWDIHAS-----------WGTIAAILLALAVLV
MUL_0640|M.ulcerans_Agy99 ---ERFASRAGAAPIFGYWDIHAS-----------WGTIAAILLALAVLV
Mflv_0468|M.gilvum_PYR-GCK PVDALWTLVHHVDAVHGFYYLLLRGWFEIVPVTEFWARVPSALMVGVAAA
. .:.* : . .: ..
MSMEG_0999|M.smegmatis_MC2_155 WGPAVAQRLPWR-----------ALPLVAWVTSALWAFSLAMIDG-WQRG
Mvan_0891|M.vanbaalenii_PYR-1 WGPPLAQRLPWR-----------WLPWLSWTVSCAWAFSLAMVDG-WQRG
Mb0555c|M.bovis_AF2122/97 WGPVVAHRLPWR-----------VLTLSTWATAAAWAFSLAMIDG-WQRG
Rv0541c|M.tuberculosis_H37Rv WGPVVAHRLPWR-----------VLTLSTWATAAAWAFSLAMIDG-WQRG
MAV_4603|M.avium_104 WGPVLAQRLSWR-----------ALTLGSWAVAAGWAFALAMIDG-WQRG
MMAR_0887|M.marinum_M WGPRVARKLSWR-----------VLPLATWATACGWAFSLAMIDG-FERG
MUL_0640|M.ulcerans_Agy99 WGPRVARKLSWR-----------VLPLATWATACGWPFSLAMIDG-FERG
Mflv_0468|M.gilvum_PYR-GCK GTCVLGSRLSGRKVGIAAGVVFAVLPRTTWAAVEARPYALSMACAVWLTV
:. :*. * *. :*.. .::*:* . :
MSMEG_0999|M.smegmatis_MC2_155 FAGRLTARHEYLRQVPSVTDIGEALRTFSSRILDFQPDSWITHVSGHPPG
Mvan_0891|M.vanbaalenii_PYR-1 FAGRLTARHEYLRQVPTVTDIPEALRTFAGRILDYQPDSWITHVSGHPPG
Mb0555c|M.bovis_AF2122/97 FAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPG
Rv0541c|M.tuberculosis_H37Rv FAGRLTTRDEYLWQVPGIADIPATLRTFTSRILDFQPNSWVTHVSGHPPG
MAV_4603|M.avium_104 FAGRLTTRDEYLWEVPRVTDIAAAVRTFSSRIVDYQPHSWTTHVSGHPPG
MMAR_0887|M.marinum_M FAGRLTTKDEYLSEVGGVTDIPVMLRTFASRIVDYQPNSWTTHVSGHPPG
MUL_0640|M.ulcerans_Agy99 FAGRLTTKDEYLSEVGGVTDIPVMLRTFASRIVDYQPNSWTTHVSGHPPG
Mflv_0468|M.gilvum_PYR-GCK LFVAAVRRGGRRWWLGYGAALVGAVTVNVMVVLILAG--HAAMLAATRPD
: . : : : : : . :: : ::. *.
MSMEG_0999|M.smegmatis_MC2_155 ALLTFVWLDRIGLGGGAWAGLLCLLVGSSAAAAIVVALR-----------
Mvan_0891|M.vanbaalenii_PYR-1 ALLTFVWLDRIGLGGGAWAGLLCLLAGSSIAAAIVVTVR-----------
Mb0555c|M.bovis_AF2122/97 ALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVR-----------
Rv0541c|M.tuberculosis_H37Rv ALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVR-----------
MAV_4603|M.avium_104 ALLTFVWLDRLGLHGGGWAGLLCLLAGSSAAAAVLIGVR-----------
MMAR_0887|M.marinum_M ALLTFVWLDRIGLGGGAWAGFLCLLVGSSAAAAMVIAVG-----------
MUL_0640|M.ulcerans_Agy99 ALLTFVWLDRIGLGGGAWAGFLCLLVGSSAAAAMVIAVG-----------
Mflv_0468|M.gilvum_PYR-GCK RRTVRAWLVTVVVASVALIPLFVVLLSQQAQIAWIWPVGPVTLGQIAGEQ
. .** : : . . :. :* ... * : :
MSMEG_0999|M.smegmatis_MC2_155 ---AVSGEATARLAAPFVAVAPTAIWIAVSADGYFAGVAAWGLALLALAV
Mvan_0891|M.vanbaalenii_PYR-1 ---ALADEDTARAAAPFVAVAPTAIWIAVSADGYFAGVAAWGITLLALAV
Mb0555c|M.bovis_AF2122/97 ---VLASEQMARRTAPFVAVAPTAIWVAVSADGYFAGVAAWGIALLAVAV
Rv0541c|M.tuberculosis_H37Rv ---VLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAV
MAV_4603|M.avium_104 ---ALADEPTARRAAPFVALAPTAIWVAVSADGYFAGVAAWGIALLAVAV
MMAR_0887|M.marinum_M ---ALAGEHVARRAAPFVAIAPTAIWIAVSADGYFAGVTAWGITLLAIAV
MUL_0640|M.ulcerans_Agy99 ---ALAGKHVARRAAPFVAIAPTAIWIAVSADGYFAGVTAWGITLLAIAV
Mflv_0468|M.gilvum_PYR-GCK YFPSVYSDSVRAVGPDQQQFSAEQLRVAMSAWARVAPLIVVIVIVAALAV
: .. . .:. : :*:** . .* : . : : *:**
MSMEG_0999|M.smegmatis_MC2_155 RDSVHRRRVA--------LPTAVGSGLLLGWGIFLNYGLALAALIALAVL
Mvan_0891|M.vanbaalenii_PYR-1 RGSVRQP-----------VAAAIGSGLLLGWAVFLNYGLVLMAFPAVAVL
Mb0555c|M.bovis_AF2122/97 HGATRFP-----------ALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVL
Rv0541c|M.tuberculosis_H37Rv HGATRFP-----------ALVAAGAGLLLGWGVFLNYGLVLIVLPGMAVL
MAV_4603|M.avium_104 HRPLRFP-----------ALTAAGAGLLLGWGVFCNYGLMLMGLPAAAVL
MMAR_0887|M.marinum_M HGGSRFR-----------ALWAAGAGLVLGWAIFLSYGLALMGLPALAVL
MUL_0640|M.ulcerans_Agy99 HGGSRFR-----------ALWAAGAGLVLGWAIFLSYGLALMGLPALAVL
Mflv_0468|M.gilvum_PYR-GCK RARRRHGALIENPSGTRVLVLGAVAWIVVPTVVLLGYSVLVRPLYQPHYL
: : . : ::: :: .*.: : : *
MSMEG_0999|M.smegmatis_MC2_155 ITAP--------DWRAALRVAVPAVIAVLAVVAVFLVAGFWWFDGYTLVQ
Mvan_0891|M.vanbaalenii_PYR-1 LGAA--------TWQAAVRTLVPAVVAALAVVAVFAAAGFWWFDGYLLVQ
Mb0555c|M.bovis_AF2122/97 AAA---------DWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQ
Rv0541c|M.tuberculosis_H37Rv AAA---------DWRPVLRALGPAVLAALVVAVSFAVAGFSWFDGYTLVQ
MAV_4603|M.avium_104 AAAPRPPRDGWTQWRAVLRALGPAALAAIAVAVAFAVAGFYWFDGYTLVQ
MMAR_0887|M.marinum_M ASAN--------HWRTALKALWPAVLAALGVALAFAVAGFWWFDGYTLVQ
MUL_0640|M.ulcerans_Agy99 ASAN--------HWRTALKALWPAVLAALGVALAFAVAGFWWFDGYTLVQ
Mflv_0468|M.gilvum_PYR-GCK TFTTP-----ALALLIGLCVVTLCRDDTRRLTATLAVLAVAAAPNYLAQR
: : . . . :. : . .. .* :
MSMEG_0999|M.smegmatis_MC2_155 ERYWQG-IANNRPFQYWSWANLASVVCAIGLGSVAGIGRVFDIKAARRNP
Mvan_0891|M.vanbaalenii_PYR-1 ERYWQG-IANDRPFQYWGWANFASVVCAIGLGSVAGLGRVFDIAAIKRRS
Mb0555c|M.bovis_AF2122/97 QRYWQG-IAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRS
Rv0541c|M.tuberculosis_H37Rv QRYWQG-IAKDRPFGYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRS
MAV_4603|M.avium_104 QRYWQG-IAKDRPFQYWSWANLACVVCAIGLGGVAGVGRVFDRAAIRRRS
MMAR_0887|M.marinum_M QRYWQG-IAHDRPFQYWSWANLACVVCAIGLGSVAGISRVVDAAAIRRRS
MUL_0640|M.ulcerans_Agy99 QRYWQG-IAHDRPFQYWSWANLACVVCAIGLGSVAGISRVVDAAAIRRRS
Mflv_0468|M.gilvum_PYR-GCK GPYAKYGSDYSQVAELLARESGPRDCVVVDDRTAPSVPHAIEGARRAHPV
* : .: . . . .:. ...: :..: :
MSMEG_0999|M.smegmatis_MC2_155 GLPMLVIGALLAITFADLSMLSKAETERIWLPFTVWLTAAGALLPPRSHR
Mvan_0891|M.vanbaalenii_PYR-1 GLHLLVLGALLAIVVADLSRLSKAETERIWLPFTVWLVASTALLPPRSAR
Mb0555c|M.bovis_AF2122/97 GCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHR
Rv0541c|M.tuberculosis_H37Rv GCHLLLLAVLAAIALADLSMLSKAETERIWLPFTIWLTAAPALLPPRSHR
MAV_4603|M.avium_104 GFPLLLLAVLAAAACADLSMLSKAEVERIWLPFTIWLTAAAALLPVRTHR
MMAR_0887|M.marinum_M GLHLLLLGMVAAILVADLSMLSKAETERIWLPFTVWLTTAPALLRPRSDR
MUL_0640|M.ulcerans_Agy99 GLHLPLLGMVAAILVADLSMLSKAETERIWLPFTVWLTTAPALLRPRSDR
Mflv_0468|M.gilvum_PYR-GCK AARDLGLAPPERTALFSARDPLGVRADDLRTCAVLWTIGDAAPGSPADAP
. :. . ...: : .:* *
MSMEG_0999|M.smegmatis_MC2_155 WWLGLNVAGALALNHLILTNW------------
Mvan_0891|M.vanbaalenii_PYR-1 WWLALNVIGALAINHLILTNW------------
Mb0555c|M.bovis_AF2122/97 LWLAVNAAGALLLNSIIFTNW------------
Rv0541c|M.tuberculosis_H37Rv LWLAVNAAGALLLNSIIFTNW------------
MAV_4603|M.avium_104 IWLALNAVGALAVNTIILTHW------------
MMAR_0887|M.marinum_M LWLAVNAAGALAVNSIIFTNW------------
MUL_0640|M.ulcerans_Agy99 LWLAVNAAGALAVNSIIFTNW------------
Mflv_0468|M.gilvum_PYR-GCK VDRVARAQGFVPAERWRFNQTEVVRSVPAGARS
.. * : : :.: