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LAWPTDHLTEAADYWETVSERTFGIAHQVWRDALSADWRGAAAETLRGATHADMTSTSAVADQLRAAASV ARGGASDLSAARSRVRYAVEDAHSAGFDVGEDLSIRDRTVGGSTAQRAARQAQARALAGDIRQRAAQLVS LDQEVAGKITAAVAGVRDTFPHDPTANRPSTDGHVRGVDNHTFKDAPSSGMSREQAKAGLKDVNKRIWEH NHIDKPVIEQLPPNDPRRADFHVETEQLNAEKQQYLDVLFHQHPPESVVGPHGEQLPGVPSGESAIGPAE SGKGWQFSLPPGHAGIDPRVTTIRVMEPTAQYPDGYVVYMNGMGQTVNPFTGRTIPPSDDYAHIPLPE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1108 | - | - | 100% (348) | hypothetical protein MAV_1108 |
| M. avium 104 | MAV_3143 | - | 1e-68 | 65.78% (187) | hypothetical protein MAV_3143 |
| M. avium 104 | MAV_1450 | - | 2e-37 | 53.85% (156) | hypothetical protein MAV_1450 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2102c | - | 2e-37 | 39.34% (244) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1972 | - | 2e-16 | 34.26% (216) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv2077c | - | 2e-37 | 39.34% (244) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0016 | - | 2e-11 | 31.79% (151) | hypothetical protein MAB_0016 |
| M. marinum M | MMAR_0482 | - | 2e-68 | 60.37% (217) | hypothetical protein MMAR_0482 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 5e-17 | 29.00% (231) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 8e-18 | 33.87% (186) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1133 | - | 8e-48 | 58.72% (172) | hypothetical protein MUL_1133 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 2e-14 | 30.13% (156) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0482|M.marinum_M -------MAASGIPDLSALLAWPTDHLTEAAAHWDNVGEHTYAVAHQLWR
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAV_1108|M.avium_104 -------------------MAWPTDHLTEAADYWETVSERTFGIAHQVWR
Mb2102c|M.bovis_AF2122/97 -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
Rv2077c|M.tuberculosis_H37Rv -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGAQG
MMAR_0482|M.marinum_M DATS---IDWSGHAAGALRAATHADLQTTSAAVDQLQEAARVARNGASDL
MUL_1133|M.ulcerans_Agy99 -----------------MRAATHADLQTTSAAVDQLQEAARVARNGASDL
MAV_1108|M.avium_104 DALS---ADWRGAAAETLRGATHADMTSTSAVADQLRAAASVARGGASDL
Mb2102c|M.bovis_AF2122/97 QAHA---IAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
Rv2077c|M.tuberculosis_H37Rv QAHA---IAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI
MAB_0016|M.abscessus_ATCC_1997 LLDG---LRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQQL
. : . * . :
MMAR_0482|M.marinum_M YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
MUL_1133|M.ulcerans_Agy99 YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
MAV_1108|M.avium_104 SAARSRVRYAVEDAHSAGFDVGEDLSIRDRTVGGSTAQRAARQAQARALA
Mb2102c|M.bovis_AF2122/97 DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
Rv2077c|M.tuberculosis_H37Rv DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNRA-YDLETAAARMTAATEHA
MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTSR-VDVSTMAARYTAAREHA
TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVLA
Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELLG
MAB_0016|M.abscessus_ATCC_1997 KGAKDKAVYAVHDPEDEDFNVNEDLSVTERRS-HSGLDRLKRAIRRRWLQ
*: . : . * * :**:: : *
MMAR_0482|M.marinum_M GDLRQRAAQLVGLDAQVATKVTAAVAGIGSSFPQIPAPAAPP--------
MUL_1133|M.ulcerans_Agy99 GDLPQRAAQLVGLDAQVATKVTAAVAGIGSSFPQIPAPAAPP--------
MAV_1108|M.avium_104 GDIRQRAAQLVSLDQEVAGKITAAVAGVRDTFPHDPTANRPS--------
Mb2102c|M.bovis_AF2122/97 GDIRLRVGQLVAAENEVSGQLAATTGDVGN----VRFAGAPV--------
Rv2077c|M.tuberculosis_H37Rv GDIRLRVGQLVAAENEVSGQLAATTGDVGN----VRFAGAPV--------
Mflv_1972|M.gilvum_PYR-GCK EFIRWRVEQLVATDALIGQQLQANAAELEGIRFEGDRDGNGTDPTIRLVD
MSMEG_5600|M.smegmatis_MC2_155 ENIQWNANQLLATDTLIGRRLTAKAAELNGVRFDDEPEG-----------
TH_3926|M.thermoresistible__bu ATVRVGAAQLVSTDHAVAQRLREATDDFDSFDFARNPIIQPL--------
Mvan_5711|M.vanbaalenii_PYR-1 ISVRTGAAQLAAVDHAVATELDSVTAGFDALNIGEGPVIAPI--------
MAB_0016|M.abscessus_ATCC_1997 GILHTRAQELVATDNAIARKLHEIAQDLSNFHLEGPDGNTDFS-------
: . :* . : :. .: . .
MMAR_0482|M.marinum_M ----------------------------------MGNPVRAVDNRTFKQN
MUL_1133|M.ulcerans_Agy99 ----------------------------------MGNPVRAVDNRTFKQN
MAV_1108|M.avium_104 ----------------------------------TDGHVRGVDNHTFKDA
Mb2102c|M.bovis_AF2122/97 ----------------------------------VAHSAVQLVDFFKQDG
Rv2077c|M.tuberculosis_H37Rv ----------------------------------VAHSAVQLVDFFKQDG
Mflv_1972|M.gilvum_PYR-GCK NKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAESAEGADTAES
MSMEG_5600|M.smegmatis_MC2_155 ------------------------------------TIRAASFGDGFKQS
TH_3926|M.thermoresistible__bu --------------------------------------STDSDEHHFG--
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------AAGDDGQSFG--
MAB_0016|M.abscessus_ATCC_1997 ----------------------------------GDPNHPKIMGPAKPLG
MMAR_0482|M.marinum_M PPPAPVDPKDMTAEEARAAWADINSEIGKYN--ARCGRTFVL--------
MUL_1133|M.ulcerans_Agy99 PPPAPVDPKDMTAEEARAAWADINSEIGKYN--ARCGRTFVL--------
MAV_1108|M.avium_104 PSSG------MSREQAKAGLKDVNKRIWEHNHIDKPVIEQLP--------
Mb2102c|M.bovis_AF2122/97 PTPP-----------PPGAPHPSGGADGPYS---DPITSMML--------
Rv2077c|M.tuberculosis_H37Rv PTPP-----------PPGAPHPSGGADGPYS---DPITSMML--------
Mflv_1972|M.gilvum_PYR-GCK PLEALLGEGETAEGQQRSSLDEALTEVAGKP--VDAPPTALERILSQHTG
MSMEG_5600|M.smegmatis_MC2_155 PFDDLLT-----KEQALAAWEKLQTDIASYN--SRCAVNIVG--------
TH_3926|M.thermoresistible__bu ----------------TCFAESFKEDVGKNMVQGVFVGGAIG--------
Mvan_5711|M.vanbaalenii_PYR-1 ----------------QCFADRFKDDIGENMVQGVFVGGALG--------
MAB_0016|M.abscessus_ATCC_1997 PIEQEDYDLGYTFLDENGNPLPMLDENGNVVIDPKTGRPVPDSVWG----
MMAR_0482|M.marinum_M ------------PTEQGAYDACIADKGPLLD----------------RQA
MUL_1133|M.ulcerans_Agy99 ------------PTEQGAYDACIADKGPLLD----------------RQA
MAV_1108|M.avium_104 ------------PNDPRRADFHVETEQLNAE----------------KQQ
Mb2102c|M.bovis_AF2122/97 ------------PPAGTEAPVSDATKRWVDN----------------MVN
Rv2077c|M.tuberculosis_H37Rv ------------PPAGTEAPVSDATKRWVDN----------------MVN
Mflv_1972|M.gilvum_PYR-GCK TGRGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESAQGALDDA
MSMEG_5600|M.smegmatis_MC2_155 ------------PLPPPQYAACQQELAFLQG----------------QEA
TH_3926|M.thermoresistible__bu ------------AARGALMGILGGPIGVFGG-------------------
Mvan_5711|M.vanbaalenii_PYR-1 ------------ALRGAVLGVLGGPLGMLGG-------------------
MAB_0016|M.abscessus_ATCC_1997 -----------DPADNNADGSPRVPHPPRDHHFADMD----------AND
.
MMAR_0482|M.marinum_M AIRARLGQLGIPVEGE--------------DPTHPGTAEPPFPPPTRING
MUL_1133|M.ulcerans_Agy99 VIRARLGQLGIPVEGE--------------DPTHPGTAEPPFPPPTRING
MAV_1108|M.avium_104 YLDVLFHQH--PPESV--------------VGPH-GEQLPGVPSGESAIG
Mb2102c|M.bovis_AF2122/97 ELAARPPDDPIAVEAR--------------RLAFQALHRP----------
Rv2077c|M.tuberculosis_H37Rv ELAARPPDDPIAVEAR--------------RLAFQALHRP----------
Mflv_1972|M.gilvum_PYR-GCK LAQSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLNAAADEVG
MSMEG_5600|M.smegmatis_MC2_155 ALRARLADFGIHPG----------------EAPSSTSSGGDLTATATQIG
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 PYRTLPTGTTVGPNGE------------RIALVSRPPDDPAWAENQTKNG
MMAR_0482|M.marinum_M --------LTEHG-AQRVEGRDGHGVNDNAMQDAVAHPIEPPQFMPDQYG
MUL_1133|M.ulcerans_Agy99 --------LTEHG-AQRVEGRDGHGVNDNAMQDAVAHPIEPPQFMPDQYG
MAV_1108|M.avium_104 --------PAESGKGWQFSLPPGHAGIDPRVT--TIRVMEPTAQYPDGY-
Mb2102c|M.bovis_AF2122/97 -----------CNSAEWTAAVAGFAGSSAGVVGTALAIPAGPADWALLGA
Rv2077c|M.tuberculosis_H37Rv -----------CNSAEWTAAVAGFAGSSAGVVGTALAIPAGPADWALLGA
Mflv_1972|M.gilvum_PYR-GCK QGRVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDVAHDIDVF
MSMEG_5600|M.smegmatis_MC2_155 ------------AEIATFPPGTRADALAERMTGLHLNQADAARATDIAAA
TH_3926|M.thermoresistible__bu ----------------GVLGFVGGAAGGALISGPARTAVTSAWDCL----
Mvan_5711|M.vanbaalenii_PYR-1 ----------------SVAGFVGGAAGGAMISGPARTAVTSAWDCL----
MAB_0016|M.abscessus_ATCC_1997 KS----VYVTQTEAYDVTRQPPQSLGKLQGVDGSKVYQGSIVYDKASGRM
MMAR_0482|M.marinum_M GTWRYIGK-----------DATVSLNENGQVTTAWANSRNGWRNP-----
MUL_1133|M.ulcerans_Agy99 GTWRYIGK-----------DATVSLNENGQVTTAWANSRNGWRNP-----
MAV_1108|M.avium_104 -VVYMNGM-----------GQTVNPFTGRTIPPSDDYAHIPLPE------
Mb2102c|M.bovis_AF2122/97 ALLGVGGS-----------GAAVVNCATK---------------------
Rv2077c|M.tuberculosis_H37Rv ALLGVGGS-----------GAAVVNCATK---------------------
Mflv_1972|M.gilvum_PYR-GCK RNWSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVNAGRHVDD
MSMEG_5600|M.smegmatis_MC2_155 RIWGETG------------GTSKMPDGSIIVLPANIRQTDVMKVFPDGSV
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 YVVGNHGDGSGDTARGMWRSDPVDPNHPNDWVKTLRYQGDVPSLPGSRES
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAV_1108|M.avium_104 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK ALDAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGNFGFEDAN
MSMEG_5600|M.smegmatis_MC2_155 TVLRGVDVTQYLPR------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 SLVALPHGGVALFGADDYAPAEGRNMAVGAISAATPEGLLQARPVTDLLP
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAV_1108|M.avium_104 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK ALLQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATADEAASAV
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 AGKTPWPGGAPYAALPTGVHWDPALRADVVDTRVSIWRDVPGVRGAYPPV
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAV_1108|M.avium_104 --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK STALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGSTVRV
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 TYQTSVPIFQPNS-------------------------------------
MMAR_0482|M.marinum_M -------------------
MUL_1133|M.ulcerans_Agy99 -------------------
MAV_1108|M.avium_104 -------------------
Mb2102c|M.bovis_AF2122/97 -------------------
Rv2077c|M.tuberculosis_H37Rv -------------------
Mflv_1972|M.gilvum_PYR-GCK VLKGDGNGGWYVLTGFPKP
MSMEG_5600|M.smegmatis_MC2_155 -------------------
TH_3926|M.thermoresistible__bu -------------------
Mvan_5711|M.vanbaalenii_PYR-1 -------------------
MAB_0016|M.abscessus_ATCC_1997 -------------------