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VALPHAILVSLSEQAGSGYELANRFDRSIGHFWTATHQQIYRTLRLMESNGWVHAKPVVQHGRPDKKVYS VSDNGRQELARWIAEPPSPTRPGRASALTDSSTRDIAVKLRGAVYGDRETLRSQVAALRAERVQALDTYR GIEKHSFPDPSALSGAALHQYVVLRGGIRAEESAIEWLGEVAQALEEK
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4275 | - | - | 100% (188) | hypothetical protein MMAR_4275 |
| M. marinum M | MMAR_0152 | - | 1e-18 | 26.84% (190) | hypothetical protein MMAR_0152 |
| M. marinum M | MMAR_3454 | - | 7e-15 | 31.94% (191) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1209c | - | 6e-85 | 80.85% (188) | hypothetical protein Mb1209c |
| M. gilvum PYR-GCK | Mflv_1331 | - | 6e-09 | 31.63% (98) | PadR-like family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1176c | - | 6e-85 | 80.85% (188) | hypothetical protein Rv1176c |
| M. leprae Br4923 | MLBr_02691 | - | 5e-06 | 23.50% (183) | hypothetical protein MLBr_02691 |
| M. abscessus ATCC 19977 | MAB_1326c | - | 3e-50 | 54.05% (185) | hypothetical protein MAB_1326c |
| M. avium 104 | MAV_0135 | - | 2e-18 | 31.49% (181) | transcriptional regulator, PadR family protein |
| M. smegmatis MC2 155 | MSMEG_6605 | - | 1e-19 | 29.69% (192) | transcriptional regulatory protein |
| M. thermoresistible (build 8) | TH_1310 | - | 0.0001 | 22.28% (184) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1024 | - | 1e-104 | 98.94% (188) | hypothetical protein MUL_1024 |
| M. vanbaalenii PYR-1 | Mvan_5461 | - | 5e-11 | 37.65% (85) | PadR-like family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1331|M.gilvum_PYR-GCK -----------------------------------------------MSI
Mvan_5461|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1209c|M.bovis_AF2122/97 --------------------------------------------------
Rv1176c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_4275|M.marinum_M --------------------------------------------------
MUL_1024|M.ulcerans_Agy99 MWAVTRLDPGFFRATVRPSVRLLILDVAYTTQLIGTLVGVRRLYAPSCIA
MAB_1326c|M.abscessus_ATCC_199 --------------------------------------------------
MAV_0135|M.avium_104 --------------------------------------------------
MSMEG_6605|M.smegmatis_MC2_155 --------------------------------------------------
MLBr_02691|M.leprae_Br4923 --------------------------------------------------
TH_1310|M.thermoresistible__bu --------------------------------------------------
Mflv_1331|M.gilvum_PYR-GCK VECHRYYSSMSLRMAALGLLAQHPASGYDLLKKFEVSMANVWPGTQSQLY
Mvan_5461|M.vanbaalenii_PYR-1 ---------MSLRIAALGLLAEGSASGYDLLKQFEKSMANVWPATQSQLY
Mb1209c|M.bovis_AF2122/97 ---------MALPHAILVSLCEQASSGYELARRFDRSIGYFWTATHQQIY
Rv1176c|M.tuberculosis_H37Rv ---------MALPHAILVSLCEQASSGYELARRFDRSIGYFWTATHQQIY
MMAR_4275|M.marinum_M ---------MALPHAILVSLSEQAGSGYELANRFDRSIGHFWTATHQQIY
MUL_1024|M.ulcerans_Agy99 PRGAIYAARVALPHAILVSLSEQAGSGYELAHRFDRSIGHFWTATHQQIY
MAB_1326c|M.abscessus_ATCC_199 ---------MALTHALLLSLAEQSGSGYELTNRFDRSIGYFYSATHQQIY
MAV_0135|M.avium_104 ---------MSLRDAVLAALLEGESSGYDLAKDFDASVANFWPATPQQLY
MSMEG_6605|M.smegmatis_MC2_155 ---------MALRDAVLAALLEGESSGYDLAKSFDASVANFWTATPQQLY
MLBr_02691|M.leprae_Br4923 ----------MLELAILGLLIESPMHGYELRKRLTGLLGAFRAFSYGSLY
TH_1310|M.thermoresistible__bu -------VIRLLELAILGLLLESPMHGYELRKRLTGLLGAFRAFSYGSLY
* * * * : **:* . : :. . . : .:*
Mflv_1331|M.gilvum_PYR-GCK SELNKLADDGLIEVTAIG---ARGR---KEYAITRPGRDELRRWVMDFHD
Mvan_5461|M.vanbaalenii_PYR-1 SELNKLAAGGLIEVCAVG---PRGR---KEYRITDAGRAELQRWVAERQD
Mb1209c|M.bovis_AF2122/97 RTLRVMENNNWVRATTVL---QHGRPDKKVYAISDSGRAELARWIAEPLS
Rv1176c|M.tuberculosis_H37Rv RTLRVMENNNWVRATTVL---QHGRPDKKVYAISDSGRAELARWIAEPLS
MMAR_4275|M.marinum_M RTLRLMESNGWVHAKPVV---QHGRPDKKVYSVSDNGRQELARWIAEPPS
MUL_1024|M.ulcerans_Agy99 RTLRLMESNGWVHAKPVV---QHGRPDKKVYSVSDNGRQELARWIAEPPS
MAB_1326c|M.abscessus_ATCC_199 RTLRRMEDDSWLHCQVVD---QEGRPAKKVYTVAELGYRELSRWIASS--
MAV_0135|M.avium_104 RELDRLAGQGLIRARVVH---QQRRPNKRMFSLTAAGRAAIRRFTATAPR
MSMEG_6605|M.smegmatis_MC2_155 RELERLAADGLIEARVVE---QERRPNKRMFSLTDAGRAALREFTAKAPK
MLBr_02691|M.leprae_Br4923 PALRRMQADRLITGHVAPAGTP-VRRARQVYQLTDAGRRRFSELVTDTGP
TH_1310|M.thermoresistible__bu PALRRMQADGLIVEDPAPDGTPKVRRARRVYRLTEAGKQRFTELVADTGP
* : : * : : :: * : .
Mflv_1331|M.gilvum_PYR-GCK D----------PPQRSSALLRVFLLSAVPSEEAGKYMIAVAEHAERDLAR
Mvan_5461|M.vanbaalenii_PYR-1 D----------PPVRSAGLLRVFLLGLVPPEQARAHLHAMAEEADGEVRR
Mb1209c|M.bovis_AF2122/97 PTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAERVKSLDT
Rv1176c|M.tuberculosis_H37Rv PTRPGRGSALTDSSTRDIAVKLRGAGYGDVAALYTQVTALRAERVKSLDT
MMAR_4275|M.marinum_M PTRPGRASALTDSSTRDIAVKLRGAVYGDRETLRSQVAALRAERVQALDT
MUL_1024|M.ulcerans_Agy99 PTRPGRASALTDSSTRDIAVKLRGAVYGDRETLRSQVAALRAGRVQALDT
MAB_1326c|M.abscessus_ATCC_199 ----------EGTDMRDLALKVRAATYADSDVVIEQIRAQRNAHAAALEG
MAV_0135|M.avium_104 P----------SVIRDELLIKVQAADAGDMRAVRDAIRERRDWATAKLAR
MSMEG_6605|M.smegmatis_MC2_155 P----------STIRDELLIKVNAVDAGDAAAVRDAVTEQLRWATEKLAR
MLBr_02691|M.leprae_Br4923 D----------NYTDNGFGVHLAFFNRTPAEARMRILEGRRRRVE---ER
TH_1310|M.thermoresistible__bu Q----------NYSDDGFGVHLAFFNRTPAEARMRILEGRRRQVE---ER
::: :
Mflv_1331|M.gilvum_PYR-GCK YEALRDAVPWNQSDD------DDFYGRAALEFGLRQAAMTADWARWVADG
Mvan_5461|M.vanbaalenii_PYR-1 LTELRESLTGGRAADP---TDESFFGFAALDYGLRLNAMQAEWARSVIDR
Mb1209c|M.bovis_AF2122/97 YRGIEKRTFADPS----ALDGAALHQYLVLRGGIRAEESAIDWLDEVAEA
Rv1176c|M.tuberculosis_H37Rv YRGIEKRTFADPS----ALDGAALHQYLVLRGGIRAEESAIDWLDEVAEA
MMAR_4275|M.marinum_M YRGIEKHSFPDPS----ALSGAALHQYVVLRGGIRAEESAIEWLGEVAQA
MUL_1024|M.ulcerans_Agy99 YRGIEKHSFPDPS----ALSGAALHQYVVLRGGIRAEESAIEWLGEVAQA
MAB_1326c|M.abscessus_ATCC_199 YLHMQKRQFPAPD----QLSGAALHQYLVLRGGIRMEEGFTDWCDEMLSA
MAV_0135|M.avium_104 YQRLRARLLDGRSEEDYLARAERIGPYLTLIRGISFEEDNIRWAEHALAV
MSMEG_6605|M.smegmatis_MC2_155 YERMRIRMLAGRSEDEFVAGTDRIGPYLTLLRGISFEQENVRWAEQALDL
MLBr_02691|M.leprae_Br4923 REGLREAVTRASN-------SFDRYTRQLHQLGLESSEREVKWLNELIAA
TH_1310|M.thermoresistible__bu REGLREAIARASN-------SFDRYTRQLHQLGLESSEREVNWLNDLIAA
:. *: *
Mflv_1331|M.gilvum_PYR-GCK IRARQK--------------------
Mvan_5461|M.vanbaalenii_PYR-1 LDT-----------------------
Mb1209c|M.bovis_AF2122/97 LQEKR---------------------
Rv1176c|M.tuberculosis_H37Rv LQEKR---------------------
MMAR_4275|M.marinum_M LEEK----------------------
MUL_1024|M.ulcerans_Agy99 LEEK----------------------
MAB_1326c|M.abscessus_ATCC_199 LSSSHVPARTDESEIDE---------
MAV_0135|M.avium_104 IARRLPTTDADSDAGDSRLVGPATNG
MSMEG_6605|M.smegmatis_MC2_155 LRRRMDP------GRQGRMLRSVRRT
MLBr_02691|M.leprae_Br4923 ERALLGRVEQT---------------
TH_1310|M.thermoresistible__bu ERMAQGRAEQP---------------