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MPESGFTLGDQPGLDEVARTDLLLDALAGRERFSLNDPDDDALAALMGEWRDDLRWPPASALVSQNEAVD ALILGLSERRRSRRAWAAIGSVAATLLALSGLGAVVADARPGDLLYGLHAMLFNEPRVSEDQIMLSAKAD LAKAEQMIAQGQWDQAESQLAEVSSTLQTVNDGSRRQHLLNELNQLNTKVEKRDPNATLPAGGPPQSGPT GVLAPQVPPGNSLTPLAPETVSPVPPNESGAPESAPAPSASPTTTGAKPSASLPPAGATATSPAPTSVPT PPVSAVVPGETPADTSVVAPGSPAAAGVAAPGPAKLAAPGDATNPGSPVVQTSGQPEPVEPAPAGPVS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0898 | - | - | 100% (348) | hypothetical protein MUL_0898 |
| M. ulcerans Agy99 | MUL_1004 | - | 4e-14 | 39.10% (133) | hypothetical protein MUL_1004 |
| M. ulcerans Agy99 | MUL_3509 | - | 1e-10 | 31.02% (187) | proline rich membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3447c | - | 1e-91 | 57.56% (311) | hypothetical protein Mb3447c |
| M. gilvum PYR-GCK | Mflv_4911 | - | 4e-51 | 34.96% (369) | hypothetical protein Mflv_4911 |
| M. tuberculosis H37Rv | Rv3413c | - | 1e-91 | 57.56% (311) | hypothetical protein Rv3413c |
| M. leprae Br4923 | MLBr_00907 | - | 7e-08 | 30.38% (158) | hypothetical protein MLBr_00907 |
| M. abscessus ATCC 19977 | MAB_3723c | - | 6e-38 | 29.88% (338) | hypothetical protein MAB_3723c |
| M. marinum M | MMAR_1135 | - | 1e-175 | 99.04% (312) | hypothetical protein MMAR_1135 |
| M. avium 104 | MAV_4358 | - | 2e-65 | 52.67% (262) | hypothetical protein MAV_4358 |
| M. smegmatis MC2 155 | MSMEG_1600 | - | 2e-50 | 34.48% (348) | hypothetical protein MSMEG_1600 |
| M. thermoresistible (build 8) | TH_3373 | - | 4e-52 | 36.19% (362) | PUTATIVE hypothetical protein Mjls_1192 |
| M. vanbaalenii PYR-1 | Mvan_1509 | - | 1e-52 | 34.88% (387) | hypothetical protein Mvan_1509 |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0898|M.ulcerans_Agy99 -------MPESGFTL-------GDQPGLDEVARTDLLLDALAGRERFS--
MMAR_1135|M.marinum_M -------MPESGFAL-------GDQPGLDEVARTDLLLDALAGRERFS--
Mb3447c|M.bovis_AF2122/97 -------MREFGNPL-------GDRPPLDELARTDLLLDALAEREEVD--
Rv3413c|M.tuberculosis_H37Rv -------MREFGNPL-------GDRPPLDELARTDLLLDALAEREEVD--
MAV_4358|M.avium_104 --------------M-------TVPESLDEFARTDLLLDALAQRRPVPR-
Mflv_4911|M.gilvum_PYR-GCK -------MPDFGRRD-----PGGGDPSLTDINRTDQFLDALAAQQQPFVT
Mvan_1509|M.vanbaalenii_PYR-1 -------MPDHGRWN-----SGG-DPSLNEINRTDQFLDALASQQPVYAT
TH_3373|M.thermoresistible__bu -------MADFGRWNPNWNPDDGGQPSLQDIHRSEQFIEALSTGRPVYAN
MSMEG_1600|M.smegmatis_MC2_155 -------MPDFGRWT-----SNGGDPSLNEINRTDRFIEALSLEQPVYST
MAB_3723c|M.abscessus_ATCC_199 MADGRGWFPGQGGWQ-----ENEGPEDLAALRRTNRMIDAIAADLPVATS
MLBr_00907|M.leprae_Br4923 -------MKAQRDTPIRRG-DSGRPGGRDGAARSGKRTANEAGSRRLRTH
*: :
MUL_0898|M.ulcerans_Agy99 -----LNDPDD---DALAALMGEWRDDLRWPPASALVSQNEAVDALILGL
MMAR_1135|M.marinum_M -----LNDPDD---DALAALMGEWRDDLRWPPASALVSQNEAVDALILGL
Mb3447c|M.bovis_AF2122/97 -----FADPRD---DALAALLGQWRDDLRWPPASALVSQDEAVAALRAGV
Rv3413c|M.tuberculosis_H37Rv -----FADPRD---DALAALLGQWRDDLRWPPASALVSQDEAVAALRAGV
MAV_4358|M.avium_104 ---GQVEDPDDPDFQMLTTLLEDWRDNLRWPPASALVTPEEAVNALRAGL
Mflv_4911|M.gilvum_PYR-GCK DRDD----------VELAQLLAGWRDDIRETPMGHVVTPLQAEAALDR-V
Mvan_1509|M.vanbaalenii_PYR-1 DRGE----------AELAHLLAGWRDDVRETPMGHVMTAEDAAIALGR-V
TH_3373|M.thermoresistible__bu DPGE----------DELAYLMAGWRDRARNAPMRATITEQDAVAALQRGL
MSMEG_1600|M.smegmatis_MC2_155 DPEE----------AELAFLLAGWRDDVRQAPMTGIINPREAVVALDRAV
MAB_3723c|M.abscessus_ATCC_199 DSDE----------YAVAMMLAAWREDVGREPMPAKPTLGQARNALRDRG
MLBr_00907|M.leprae_Br4923 AGKISAS------AREVGVPKSGPRTSPMSRPVERPARPRNTTQAKARAK
: * * :: *
MUL_0898|M.ulcerans_Agy99 SERR------RSRRAWAAIGSVAATLLALSGLGAVVADARPGDLLYGLHA
MMAR_1135|M.marinum_M SERR------RSRRAWAAIGSVAATLLALSGLGAVVADARPGDLLYGLHA
Mb3447c|M.bovis_AF2122/97 AQRR------RARRSLAAVGSVAAALLVLSGFGAVVADARPGDLLYGLHA
Rv3413c|M.tuberculosis_H37Rv AQRR------RARRSLAAVGSVAAALLVLSGFGAVVADARPGDLLYGLHA
MAV_4358|M.avium_104 AERR------RGHRGLAVVGSVAATLMLLSGFGAMVVEARPGSTLYGLHA
Mflv_4911|M.gilvum_PYR-GCK TRPAA----PRRRFSLAVVGSAAAAVLAIGGFGAVVAGSGPGDALYGLRT
Mvan_1509|M.vanbaalenii_PYR-1 TKP------PRRRLSLAVIGSAAAAVLAIGGVGAVVAGSGPGDALYGLRT
TH_3373|M.thermoresistible__bu PRPRGGAPRPGRRFSLTVVGSAAAAVICLGGFGALVAGAGPGDPLYGLRT
MSMEG_1600|M.smegmatis_MC2_155 ARN-------RPRLPLALVGSAAAAVLCLGGFGAAVYGSSPGDALYGLRG
MAB_3723c|M.abscessus_ATCC_199 GRSR---------MLATTVGSAAAVTLLFGGFGAAVYQSHPGDALYGLRT
MLBr_00907|M.leprae_Br4923 ARKAK-----APKVVRPRLGECLIARLALIDLRPRTLVNKVPFVVLVISS
. . :*. . : : .. . . : :
MUL_0898|M.ulcerans_Agy99 MLFNEPRVSE-DQIMLSAKADLAKAEQMIAQGQ-WDQAESQLAEVSSTLQ
MMAR_1135|M.marinum_M MLFNEPRVSE-DQIMLSAKADLAKAEQMIAQGQ-WDQAESQLAEVSSTLQ
Mb3447c|M.bovis_AF2122/97 MMFNRSRVSD-DQIVLSAKANLAKVEQMIAQGQ-WAEAQDELAEVSSTVQ
Rv3413c|M.tuberculosis_H37Rv MMFNRSRVSD-DQIVLSAKANLAKVEQMIAQGQ-WAEAQDELAEVSSTVQ
MAV_4358|M.avium_104 MFFDQPRVNEKDQVMLAAKADLAKVAESIDKGQ-WDQARTQLTEVSSLVA
Mflv_4911|M.gilvum_PYR-GCK MLFGEQVQMRDDAVILAAQTEMQQVQQLIEQGD-WQQAQAKLEAVTTTVA
Mvan_1509|M.vanbaalenii_PYR-1 MLFGEQAQTRDDAVILAAQTEMQQVQQLIEQGD-WAGAQAKLEAVTTTVA
TH_3373|M.thermoresistible__bu MLFGD--VVRDDPVVLAAQTQLAEVEQLIAQGD-WEAAQERLQAVTTTVA
MSMEG_1600|M.smegmatis_MC2_155 MIFGEQ-ATRDVQVELAS-TELEQVQQLIEQGD-WQAAQQKLQTLTTTVA
MAB_3723c|M.abscessus_ATCC_199 SLFGAPPAVRTDPVVLSAQTELAQVEKLISQGD-WEEAQQQLGVAAARVN
MLBr_00907|M.leprae_Br4923 LGVGLGLTLWLSTDSAERSYQLGDAREQARMLQQQKEALERDVREAESAP
.. :: .. : : * . :
MUL_0898|M.ulcerans_Agy99 TVNDGSRRQHLLNELNQLNTKVEKRDPNATLPAGGPPQSGPTGVLAPQVP
MMAR_1135|M.marinum_M TVNDGSRRQHLLNELNQLNTKVEKRDPNATLPAGGPPQSGPTGVLAPQVP
Mb3447c|M.bovis_AF2122/97 AVTDGSRRQDLINEVNLLNTKVETRDPNATLRPGSPSNPAAPGSVG----
Rv3413c|M.tuberculosis_H37Rv AVTDGSRRQDLINEVNLLNTKVETRDPNATLRPGSPSNPAAPGSVG----
MAV_4358|M.avium_104 SIDDPATKQDLMTQLNLLNAKVDTRNPNATLPAAAPS-------------
Mflv_4911|M.gilvum_PYR-GCK TVDDVAQKEELIAQWQELTVKVEAQDPVATVPPGAPLPTFPELPAAVLDQ
Mvan_1509|M.vanbaalenii_PYR-1 TVADVERKQELVTQWQELTVKVEAQDPVATVPPGSPLPTFPDVPVAVLDP
TH_3373|M.thermoresistible__bu TVGDETRKQELVAEWQELSVKVESRNPDATVPPDAPPVTLP-----VIDP
MSMEG_1600|M.smegmatis_MC2_155 TVNDEAQKQQLVTQWQQLSVKVENQDPNATVAPDAPPPVFP----EVTIT
MAB_3723c|M.abscessus_ATCC_199 EVGDAQQKAELASRVQQAEVRIDAKDPQATVPPEMVTETPRIMLSPPSIA
MLBr_00907|M.leprae_Br4923 ALAETARKQGMIPTRDTAHLVQGPGGNWVVVGTPKPADGVPPPPLN----
: : : : : . ..: .
MUL_0898|M.ulcerans_Agy99 P----GNSLTPLAPETVSPVPPNESGAPESAPAPSASPTTTGAKPSASLP
MMAR_1135|M.marinum_M P----GNSLTPLVPETVSPVPPNESGAPESAPAPSASPTTTGAKPSASLP
Mb3447c|M.bovis_AF2122/97 ------NSWTPLAPVVEPPTPP--------TPASAAEPSMSAGVSESPMP
Rv3413c|M.tuberculosis_H37Rv ------NSWTPLAPVVEPPTPP--------TPASAAEPSMSAGVSESPMP
MAV_4358|M.avium_104 -----------MAPSVAVPAAP--------PPAASIAP--TPAAPPAPLS
Mflv_4911|M.gilvum_PYR-GCK ATTSSETTAGTTSDTTAPSSETTAPSSETTGPSSETTTAP--SETTGP-A
Mvan_1509|M.vanbaalenii_PYR-1 GTSSETTSTAPSSETTSPTS-PSETTSPTSPSETTSPTSP--SETTSP-A
TH_3373|M.thermoresistible__bu ATSTEPTEPGTPSTEPAEPGEPTEPGDPDMPVDGTEPTSPGTEPTAGPDQ
MSMEG_1600|M.smegmatis_MC2_155 PPAPTDTSAVETTPGSATPSEPTSPGESATPSDTSDTSEP-SSETTVP--
MAB_3723c|M.abscessus_ATCC_199 PITS-TTTTSTTSTTSASTTTSDSTSASTSTTETSGSASPSTSSSTSTSA
MLBr_00907|M.leprae_Br4923 -----TKLPDAGPPSLKPPEIPLEVPVRVVPGPGGPPPPARSGPQMWLRV
. . .
MUL_0898|M.ulcerans_Agy99 PAGATATSPAPTSVPTPPVSAVVPGETPADTSVVAPGSPAAAGVAAPGPA
MMAR_1135|M.marinum_M PAGATATSPAPTSVPTPPVSAVVPGETPADTSVVAPGSPAAAGVAATGAG
Mb3447c|M.bovis_AF2122/97 NSTSTVAASPSTPSSKPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH-
Rv3413c|M.tuberculosis_H37Rv NSTSTVAASPSTPSSKPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH-
MAV_4358|M.avium_104 P------APVSTPSPSPSVG-----------KHHHHGQPPAVAPVNPNQ-
Mflv_4911|M.gilvum_PYR-GCK PTTTAPTSAPTTTAPAPSTTP-TTSVGQTR-SSAAPSTPPSSAPTSTTVV
Mvan_1509|M.vanbaalenii_PYR-1 PSSETTSAPTSSPSPTPSTAPTTTSVGAAPPSSSAPATTTPTSTTATRAP
TH_3373|M.thermoresistible__bu PTVPPTVGPTSEPATSEPAMTAPTTTVPTSAPGSAVRTTTSAPTTATTTS
MSMEG_1600|M.smegmatis_MC2_155 SSPTPSTAPSSSVPTATSQTPTSTQVPTSTPTSSAAVQLPSPVEEEEPAE
MAB_3723c|M.abscessus_ATCC_199 TASTSVTSVPTSTPTTVTITTTPPSSAATITSTPASATETTTAPSVSTAP
MLBr_00907|M.leprae_Br4923 PDGATTLGGQHLPQELPQLPGMLNGPAAAQVQVPGFMPTPGLPIPGSTMR
. .
MUL_0898|M.ulcerans_Agy99 KLAAPGDATNPGSPVVQTSGQPEPVEPAPAGPVS----------------
MMAR_1135|M.marinum_M --------------------------------------------------
Mb3447c|M.bovis_AF2122/97 --------------------------------------------------
Rv3413c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4358|M.avium_104 --------------------------------------------------
Mflv_4911|M.gilvum_PYR-GCK LQSTTTSAAAPTTSAAPT--TAAPTTAAPTTAVPTTPSAVETTPAVEEET
Mvan_1509|M.vanbaalenii_PYR-1 SATSTTVVQSATTTSAPL--STSSSVAAPPTPTPSPSPTPTPAPTVDEES
TH_3373|M.thermoresistible__bu GSTTAGPTAGGPTSSGPA--TGPTSVPREPGAGAGTTEPTAPAARAGEDG
MSMEG_1600|M.smegmatis_MC2_155 PQPTSVPQAPTSAPAVPAEPSGPSGDPARPPVTATTTVTLPTQAGPAQGP
MAB_3723c|M.abscessus_ATCC_199 TTSVPGVTASTTVPPTASIVTVPTTPEGVTIVTTRPGVVNTPVITAPTTI
MLBr_00907|M.leprae_Br4923 VPVPAPAPTEVPVRLQPGLVSPAVTSPVISTSPVPTPVNSEQFG------
MUL_0898|M.ulcerans_Agy99 --------------------------------------------------
MMAR_1135|M.marinum_M --------------------------------------------------
Mb3447c|M.bovis_AF2122/97 --------------------------------------------------
Rv3413c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4358|M.avium_104 --------------------------------------------------
Mflv_4911|M.gilvum_PYR-GCK P-------------PSPVAPVTTTTP----VLPLPGE-------------
Mvan_1509|M.vanbaalenii_PYR-1 V-------------PSPTAPALPTTTTPIILLPVPGEAG-----------
TH_3373|M.thermoresistible__bu VGGDGTVGGDGAFAEETVGEVPQLTATTTVVLPQSGAADAAGD-------
MSMEG_1600|M.smegmatis_MC2_155 NGRGNGPGNGAKPAEPAQPKAPEQPAVQIPLLPGMGGN------------
MAB_3723c|M.abscessus_ATCC_199 EAPVPITRTPDNPAPAYQAPVNSPGSGNLHGYPGSGGNAGSGSDGPSRHM
MLBr_00907|M.leprae_Br4923 ---------------PVTATAPGTSR------------------------
MUL_0898|M.ulcerans_Agy99 ------------------------------
MMAR_1135|M.marinum_M ------------------------------
Mb3447c|M.bovis_AF2122/97 ------------------------------
Rv3413c|M.tuberculosis_H37Rv ------------------------------
MAV_4358|M.avium_104 ------------------------------
Mflv_4911|M.gilvum_PYR-GCK ------------------------------
Mvan_1509|M.vanbaalenii_PYR-1 ------------------------------
TH_3373|M.thermoresistible__bu ------------------------------
MSMEG_1600|M.smegmatis_MC2_155 ------------------------------
MAB_3723c|M.abscessus_ATCC_199 PAMTSVPVAPANPGSGSANQGSGSGSHTDE
MLBr_00907|M.leprae_Br4923 ------------------------------