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MPESGFALGDQPGLDEVARTDLLLDALAGRERFSLNDPDDDALAALMGEWRDDLRWPPASALVSQNEAVD ALILGLSERRRSRRAWAAIGSVAATLLALSGLGAVVADARPGDLLYGLHAMLFNEPRVSEDQIMLSAKAD LAKAEQMIAQGQWDQAESQLAEVSSTLQTVNDGSRRQHLLNELNQLNTKVEKRDPNATLPAGGPPQSGPT GVLAPQVPPGNSLTPLVPETVSPVPPNESGAPESAPAPSASPTTTGAKPSASLPPAGATATSPAPTSVPT PPVSAVVPGETPADTSVVAPGSPAAAGVAATGAG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. marinum M | MMAR_1135 | - | - | 100% (314) | hypothetical protein MMAR_1135 |
M. marinum M | MMAR_4294 | - | 4e-10 | 35.85% (106) | hypothetical protein MMAR_4294 |
M. marinum M | MMAR_2120 | secD | 6e-08 | 39.81% (108) | protein-export membrane protein SecD |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3447c | - | 6e-91 | 60.73% (303) | hypothetical protein Mb3447c |
M. gilvum PYR-GCK | Mflv_4911 | - | 2e-48 | 34.06% (323) | hypothetical protein Mflv_4911 |
M. tuberculosis H37Rv | Rv3413c | - | 6e-91 | 60.73% (303) | hypothetical protein Rv3413c |
M. leprae Br4923 | MLBr_00568 | - | 9e-07 | 38.26% (115) | hypothetical protein MLBr_00568 |
M. abscessus ATCC 19977 | MAB_3723c | - | 1e-36 | 31.02% (303) | hypothetical protein MAB_3723c |
M. avium 104 | MAV_4358 | - | 2e-65 | 52.67% (262) | hypothetical protein MAV_4358 |
M. smegmatis MC2 155 | MSMEG_1600 | - | 2e-48 | 36.50% (326) | hypothetical protein MSMEG_1600 |
M. thermoresistible (build 8) | TH_3373 | - | 2e-49 | 36.47% (329) | PUTATIVE hypothetical protein Mjls_1192 |
M. ulcerans Agy99 | MUL_0898 | - | 1e-175 | 99.04% (312) | hypothetical protein MUL_0898 |
M. vanbaalenii PYR-1 | Mvan_1509 | - | 6e-50 | 38.87% (319) | hypothetical protein Mvan_1509 |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_1135|M.marinum_M -------MPESGFAL-------GDQPGLDEVARTDLLLDALAGRERFS-- MUL_0898|M.ulcerans_Agy99 -------MPESGFTL-------GDQPGLDEVARTDLLLDALAGRERFS-- Mb3447c|M.bovis_AF2122/97 -------MREFGNPL-------GDRPPLDELARTDLLLDALAEREEVD-- Rv3413c|M.tuberculosis_H37Rv -------MREFGNPL-------GDRPPLDELARTDLLLDALAEREEVD-- MAV_4358|M.avium_104 --------------M-------TVPESLDEFARTDLLLDALAQRRPVPRG Mflv_4911|M.gilvum_PYR-GCK -------MPDFGRRD-----PGGGDPSLTDINRTDQFLDALAAQQQPF-- Mvan_1509|M.vanbaalenii_PYR-1 -------MPDHGRWN-----SGG-DPSLNEINRTDQFLDALASQQPVY-- TH_3373|M.thermoresistible__bu -------MADFGRWNPNWNPDDGGQPSLQDIHRSEQFIEALSTGRPVY-- MSMEG_1600|M.smegmatis_MC2_155 -------MPDFGRWT-----SNGGDPSLNEINRTDRFIEALSLEQPVY-- MAB_3723c|M.abscessus_ATCC_199 MADGRGWFPGQGGWQ-----ENEGPEDLAALRRTNRMIDAIAADLPVA-- MLBr_00568|M.leprae_Br4923 -------------------------------------------------- MMAR_1135|M.marinum_M -LNDPDD---DALAALMGEWRDDLRWPPASALVSQNEAVDALILGLSERR MUL_0898|M.ulcerans_Agy99 -LNDPDD---DALAALMGEWRDDLRWPPASALVSQNEAVDALILGLSERR Mb3447c|M.bovis_AF2122/97 -FADPRD---DALAALLGQWRDDLRWPPASALVSQDEAVAALRAGVAQRR Rv3413c|M.tuberculosis_H37Rv -FADPRD---DALAALLGQWRDDLRWPPASALVSQDEAVAALRAGVAQRR MAV_4358|M.avium_104 QVEDPDDPDFQMLTTLLEDWRDNLRWPPASALVTPEEAVNALRAGLAERR Mflv_4911|M.gilvum_PYR-GCK -VTDRDD---VELAQLLAGWRDDIRETPMGHVVTPLQAEAALDR-VTRPA Mvan_1509|M.vanbaalenii_PYR-1 -ATDRGE---AELAHLLAGWRDDVRETPMGHVMTAEDAAIALGR-VTKP- TH_3373|M.thermoresistible__bu -ANDPGE---DELAYLMAGWRDRARNAPMRATITEQDAVAALQRGLPRPR MSMEG_1600|M.smegmatis_MC2_155 -STDPEE---AELAFLLAGWRDDVRQAPMTGIINPREAVVALDRAVARN- MAB_3723c|M.abscessus_ATCC_199 -TSDSDE---YAVAMMLAAWREDVGREPMPAKPTLGQARNALRDRGGRSR MLBr_00568|M.leprae_Br4923 -------------------------------------------------- MMAR_1135|M.marinum_M ------RSRRAWAAIGSVAATLLALSGLGAVVADARPGDLLYGLHAMLFN MUL_0898|M.ulcerans_Agy99 ------RSRRAWAAIGSVAATLLALSGLGAVVADARPGDLLYGLHAMLFN Mb3447c|M.bovis_AF2122/97 ------RARRSLAAVGSVAAALLVLSGFGAVVADARPGDLLYGLHAMMFN Rv3413c|M.tuberculosis_H37Rv ------RARRSLAAVGSVAAALLVLSGFGAVVADARPGDLLYGLHAMMFN MAV_4358|M.avium_104 ------RGHRGLAVVGSVAATLMLLSGFGAMVVEARPGSTLYGLHAMFFD Mflv_4911|M.gilvum_PYR-GCK A----PRRRFSLAVVGSAAAAVLAIGGFGAVVAGSGPGDALYGLRTMLFG Mvan_1509|M.vanbaalenii_PYR-1 -----PRRRLSLAVIGSAAAAVLAIGGVGAVVAGSGPGDALYGLRTMLFG TH_3373|M.thermoresistible__bu GGAPRPGRRFSLTVVGSAAAAVICLGGFGALVAGAGPGDPLYGLRTMLFG MSMEG_1600|M.smegmatis_MC2_155 ------RPRLPLALVGSAAAAVLCLGGFGAAVYGSSPGDALYGLRGMIFG MAB_3723c|M.abscessus_ATCC_199 ---------MLATTVGSAAAVTLLFGGFGAAVYQSHPGDALYGLRTSLFG MLBr_00568|M.leprae_Br4923 -----------MKVFDRFNTAILVSAGLCGAALAFSPSAAAAPLS----- .. :. : .*. . . *. * MMAR_1135|M.marinum_M EPRVSE-DQIMLSAKADLAKAEQMIAQGQWDQAESQLAEVSSTLQTVNDG MUL_0898|M.ulcerans_Agy99 EPRVSE-DQIMLSAKADLAKAEQMIAQGQWDQAESQLAEVSSTLQTVNDG Mb3447c|M.bovis_AF2122/97 RSRVSD-DQIVLSAKANLAKVEQMIAQGQWAEAQDELAEVSSTVQAVTDG Rv3413c|M.tuberculosis_H37Rv RSRVSD-DQIVLSAKANLAKVEQMIAQGQWAEAQDELAEVSSTVQAVTDG MAV_4358|M.avium_104 QPRVNEKDQVMLAAKADLAKVAESIDKGQWDQARTQLTEVSSLVASIDDP Mflv_4911|M.gilvum_PYR-GCK EQVQMRDDAVILAAQTEMQQVQQLIEQGDWQQAQAKLEAVTTTVATVDDV Mvan_1509|M.vanbaalenii_PYR-1 EQAQTRDDAVILAAQTEMQQVQQLIEQGDWAGAQAKLEAVTTTVATVADV TH_3373|M.thermoresistible__bu D--VVRDDPVVLAAQTQLAEVEQLIAQGDWEAAQERLQAVTTTVATVGDE MSMEG_1600|M.smegmatis_MC2_155 EQ-ATRDVQVELAS-TELEQVQQLIEQGDWQAAQQKLQTLTTTVATVNDE MAB_3723c|M.abscessus_ATCC_199 APPAVRTDPVVLSAQTELAQVEKLISQGDWEEAQQQLGVAAARVNEVGDA MLBr_00568|M.leprae_Br4923 ---MPTGGPTCIEQMAGLGAVPAAVP----AVLPGPVAGAVPSVPVVPSG : : : . : : . : : . MMAR_1135|M.marinum_M SRRQHLLNELNQLNTKVEKRDPNATLP----AGGPPQSGP---------- MUL_0898|M.ulcerans_Agy99 SRRQHLLNELNQLNTKVEKRDPNATLP----AGGPPQSGP---------- Mb3447c|M.bovis_AF2122/97 SRRQDLINEVNLLNTKVETRDPNATLR----PGSPSNPAA---------- Rv3413c|M.tuberculosis_H37Rv SRRQDLINEVNLLNTKVETRDPNATLR----PGSPSNPAA---------- MAV_4358|M.avium_104 ATKQDLMTQLNLLNAKVDTRNPNATLP----AAAPS-------------- Mflv_4911|M.gilvum_PYR-GCK AQKEELIAQWQELTVKVEAQDPVATVP----PGAPLPTFPELPAAVLDQA Mvan_1509|M.vanbaalenii_PYR-1 ERKQELVTQWQELTVKVEAQDPVATVP----PGSPLPTFPDVPVAVLDPG TH_3373|M.thermoresistible__bu TRKQELVAEWQELSVKVESRNPDATVP----PDAPPVTLP-----VIDPA MSMEG_1600|M.smegmatis_MC2_155 AQKQQLVTQWQQLSVKVENQDPNATVA----PDAPPPVFPEVTITPPAP- MAB_3723c|M.abscessus_ATCC_199 QQKAELASRVQQAEVRIDAKDPQATVPPEMVTETPRIMLSPPSIAPITST MLBr_00568|M.leprae_Br4923 GFPP--VVPPGGFPPVVPPGGFLPVVP----PGGFPPVVP---------- : . ..: . MMAR_1135|M.marinum_M ------------------------------TGVLAPQVPPGNSLTPLVPE MUL_0898|M.ulcerans_Agy99 ------------------------------TGVLAPQVPPGNSLTPLAPE Mb3447c|M.bovis_AF2122/97 ------------------------------PGSVG------NSWTPLAPV Rv3413c|M.tuberculosis_H37Rv ------------------------------PGSVG------NSWTPLAPV MAV_4358|M.avium_104 ----------------------------------------------MAPS Mflv_4911|M.gilvum_PYR-GCK TTSSETTAGTTSDTTAPSSETTAPSSETTGPSSETTTAP--SETTGPAPT Mvan_1509|M.vanbaalenii_PYR-1 TSSETTSTAPSSETTSPTS-PSETTSPTSPSETTSPTSP--SETTSPAPS TH_3373|M.thermoresistible__bu TSTEPTEPGTPSTEPAEPGEPTEPGDPDMPVDGTEPTSPGTEPTAGPDQP MSMEG_1600|M.smegmatis_MC2_155 TDTSAVETTPGSATPSEPTSPGESATPSDTSDTSEPSSE-TTVPSSPTPS MAB_3723c|M.abscessus_ATCC_199 TTTSTTSTTSASTTTSDSTSASTSTTETSGSASPSTSSSTSTSATASTSV MLBr_00568|M.leprae_Br4923 --------------------------------------------PGGFPP MMAR_1135|M.marinum_M TVSPVPPNESGAPESAPAPSASPTTTGAKPSASLPPAGATATSPAPTSVP MUL_0898|M.ulcerans_Agy99 TVSPVPPNESGAPESAPAPSASPTTTGAKPSASLPPAGATATSPAPTSVP Mb3447c|M.bovis_AF2122/97 VEPPTPP--------TPASAAEPSMSAGVSESPMPNSTSTVAASPSTPSS Rv3413c|M.tuberculosis_H37Rv VEPPTPP--------TPASAAEPSMSAGVSESPMPNSTSTVAASPSTPSS MAV_4358|M.avium_104 VAVPAAP--------PPAASIAP--TPAAPPAPLSP------APVSTPSP Mflv_4911|M.gilvum_PYR-GCK TTAPTSAPTTT--APAPSTTP-TTSVGQTR-SSAAPSTPPSSAPTSTTVV Mvan_1509|M.vanbaalenii_PYR-1 SETTSAPTSSP--SPTPSTAPTTTSVGAAPPSSSAPATTTPTSTTATRAP TH_3373|M.thermoresistible__bu TVPPTVGPTSEPATSEPAMTAPTTTVPTSAPGSAVRTTTSAPTTATTTSG MSMEG_1600|M.smegmatis_MC2_155 TAPSSSVPTAT--SQTPTSTQVPTSTPTSSAAVQLPSPVEEEEPAEPQPT MAB_3723c|M.abscessus_ATCC_199 TSVPTSTPTTVTITTTPPSSAATITSTPASATETTTAPSVSTAPTTSVPG MLBr_00568|M.leprae_Br4923 VVPPGVAPAVG-----PLLAEDSAALGSGILAGKGVPTASPQAALSGLVV . * : . . MMAR_1135|M.marinum_M TPPVSAVVPGETPADTSVVAPGSPAAAGVAATGAG--------------- MUL_0898|M.ulcerans_Agy99 TPPVSAVVPGETPADTSVVAPGSPAAAGVAAPGPAKLAAPGDATNPGSPV Mb3447c|M.bovis_AF2122/97 KPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH---------------- Rv3413c|M.tuberculosis_H37Rv KPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH---------------- MAV_4358|M.avium_104 SPSVG-----------KHHHHGQPPAVAPVNPNQ---------------- Mflv_4911|M.gilvum_PYR-GCK LQSTTTSAAAPTTSAAPTTAAPTTAAPTTAVPTTPSAVETTPAVEEET-- Mvan_1509|M.vanbaalenii_PYR-1 SATSTTVVQSATTTSAPLSTSSSVAAPPTPTPSPSPTPTPAPTVDEES-- TH_3373|M.thermoresistible__bu STTAGPTAGGPTSSGPATGPTSVPREPGAGAGTTEPTAPAARAGEDGVGG MSMEG_1600|M.smegmatis_MC2_155 SVPQAPTS-APAVPAEPSGPSGDPARPPVTATTTVTLPTQAGPAQGPNGR MAB_3723c|M.abscessus_ATCC_199 VTASTTVPPTASIVTVPTTPEGVTIVTTRPGVVNTPVITAPTTIEAPVPI MLBr_00568|M.leprae_Br4923 LPGPPASVEAPPAAAPVVAAATPLLCCGEAAPPVR--------------- MMAR_1135|M.marinum_M -------------------------------------------------- MUL_0898|M.ulcerans_Agy99 VQTSGQPEPVEPAPAGPVS------------------------------- Mb3447c|M.bovis_AF2122/97 -------------------------------------------------- Rv3413c|M.tuberculosis_H37Rv -------------------------------------------------- MAV_4358|M.avium_104 -------------------------------------------------- Mflv_4911|M.gilvum_PYR-GCK ----------PPSPVAPVTTTTP----VLPLPGE---------------- Mvan_1509|M.vanbaalenii_PYR-1 ----------VPSPTAPALPTTTTPIILLPVPGEAG-------------- TH_3373|M.thermoresistible__bu DGTVGGDGAFAEETVGEVPQLTATTTVVLPQSGAADAAGD---------- MSMEG_1600|M.smegmatis_MC2_155 GNGPGNGAKPAEPAQPKAPEQPAVQIPLLPGMGGN--------------- MAB_3723c|M.abscessus_ATCC_199 TRTPDNPAPAYQAPVNSPGSGNLHGYPGSGGNAGSGSDGPSRHMPAMTSV MLBr_00568|M.leprae_Br4923 -------------------------------------------------- MMAR_1135|M.marinum_M ------------------------ MUL_0898|M.ulcerans_Agy99 ------------------------ Mb3447c|M.bovis_AF2122/97 ------------------------ Rv3413c|M.tuberculosis_H37Rv ------------------------ MAV_4358|M.avium_104 ------------------------ Mflv_4911|M.gilvum_PYR-GCK ------------------------ Mvan_1509|M.vanbaalenii_PYR-1 ------------------------ TH_3373|M.thermoresistible__bu ------------------------ MSMEG_1600|M.smegmatis_MC2_155 ------------------------ MAB_3723c|M.abscessus_ATCC_199 PVAPANPGSGSANQGSGSGSHTDE MLBr_00568|M.leprae_Br4923 ------------------------