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MPDHGRWNSGGDPSLNEINRTDQFLDALASQQPVYATDRGEAELAHLLAGWRDDVRETPMGHVMTAEDAA IALGRVTKPPRRRLSLAVIGSAAAAVLAIGGVGAVVAGSGPGDALYGLRTMLFGEQAQTRDDAVILAAQT EMQQVQQLIEQGDWAGAQAKLEAVTTTVATVADVERKQELVTQWQELTVKVEAQDPVATVPPGSPLPTFP DVPVAVLDPGTSSETTSTAPSSETTSPTSPSETTSPTSPSETTSPTSPSETTSPAPSSETTSAPTSSPSP TPSTAPTTTSVGAAPPSSSAPATTTPTSTTATRAPSATSTTVVQSATTTSAPLSTSSSVAAPPTPTPSPS PTPTPAPTVDEESVPSPTAPALPTTTTPIILLPVPGEAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1509 | - | - | 100% (389) | hypothetical protein Mvan_1509 |
| M. vanbaalenii PYR-1 | Mvan_0433 | - | 4e-16 | 30.35% (201) | hypothetical protein Mvan_0433 |
| M. vanbaalenii PYR-1 | Mvan_0626 | - | 2e-15 | 28.49% (186) | hypothetical protein Mvan_0626 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3447c | - | 2e-48 | 38.41% (302) | hypothetical protein Mb3447c |
| M. gilvum PYR-GCK | Mflv_4911 | - | 1e-131 | 66.00% (400) | hypothetical protein Mflv_4911 |
| M. tuberculosis H37Rv | Rv3413c | - | 2e-48 | 38.41% (302) | hypothetical protein Rv3413c |
| M. leprae Br4923 | MLBr_00048 | - | 4e-09 | 26.82% (179) | hypothetical protein MLBr_00048 |
| M. abscessus ATCC 19977 | MAB_3723c | - | 1e-64 | 41.60% (387) | hypothetical protein MAB_3723c |
| M. marinum M | MMAR_1135 | - | 8e-50 | 38.87% (319) | hypothetical protein MMAR_1135 |
| M. avium 104 | MAV_4358 | - | 3e-35 | 35.47% (265) | hypothetical protein MAV_4358 |
| M. smegmatis MC2 155 | MSMEG_1600 | - | 1e-94 | 51.33% (376) | hypothetical protein MSMEG_1600 |
| M. thermoresistible (build 8) | TH_3373 | - | 9e-90 | 47.68% (388) | PUTATIVE hypothetical protein Mjls_1192 |
| M. ulcerans Agy99 | MUL_0898 | - | 9e-53 | 35.14% (387) | hypothetical protein MUL_0898 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3447c|M.bovis_AF2122/97 -------MREFGNPL-------GDRPPLDELARTDLLLDALAEREEVD--
Rv3413c|M.tuberculosis_H37Rv -------MREFGNPL-------GDRPPLDELARTDLLLDALAEREEVD--
MMAR_1135|M.marinum_M -------MPESGFAL-------GDQPGLDEVARTDLLLDALAGRERFS--
MUL_0898|M.ulcerans_Agy99 -------MPESGFTL-------GDQPGLDEVARTDLLLDALAGRERFS--
MAV_4358|M.avium_104 --------------M-------TVPESLDEFARTDLLLDALAQRRPVPRG
Mvan_1509|M.vanbaalenii_PYR-1 -------MPDHGRWN-----SGG-DPSLNEINRTDQFLDALASQQPVY--
Mflv_4911|M.gilvum_PYR-GCK -------MPDFGRRD-----PGGGDPSLTDINRTDQFLDALAAQQQPF--
TH_3373|M.thermoresistible__bu -------MADFGRWNPNWNPDDGGQPSLQDIHRSEQFIEALSTGRPVY--
MSMEG_1600|M.smegmatis_MC2_155 -------MPDFGRWT-----SNGGDPSLNEINRTDRFIEALSLEQPVY--
MAB_3723c|M.abscessus_ATCC_199 MADGRGWFPGQGGWQ-----ENEGPEDLAALRRTNRMIDAIAADLPVA--
MLBr_00048|M.leprae_Br4923 ------MAADYDKLFR----LDDGAYASPDQAAEQLFDDAPLYPPPIIPT
: : :*
Mb3447c|M.bovis_AF2122/97 -FADPRD---DALAALLGQWRDDLRWPPASALVSQDEAVAALRAGVAQRR
Rv3413c|M.tuberculosis_H37Rv -FADPRD---DALAALLGQWRDDLRWPPASALVSQDEAVAALRAGVAQRR
MMAR_1135|M.marinum_M -LNDPDD---DALAALMGEWRDDLRWPPASALVSQNEAVDALILGLSERR
MUL_0898|M.ulcerans_Agy99 -LNDPDD---DALAALMGEWRDDLRWPPASALVSQNEAVDALILGLSERR
MAV_4358|M.avium_104 QVEDPDDPDFQMLTTLLEDWRDNLRWPPASALVTPEEAVNALRAGLAERR
Mvan_1509|M.vanbaalenii_PYR-1 -ATDRGE---AELAHLLAGWRDDVRETPMGHVMTAEDAAIALGR-VTKP-
Mflv_4911|M.gilvum_PYR-GCK -VTDRDD---VELAQLLAGWRDDIRETPMGHVVTPLQAEAALDR-VTRPA
TH_3373|M.thermoresistible__bu -ANDPGE---DELAYLMAGWRDRARNAPMRATITEQDAVAALQRGLPRPR
MSMEG_1600|M.smegmatis_MC2_155 -STDPEE---AELAFLLAGWRDDVRQAPMTGIINPREAVVALDRAVARN-
MAB_3723c|M.abscessus_ATCC_199 -TSDSDE---YAVAMMLAAWREDVGREPMPAKPTLGQARNALRDRGGRSR
MLBr_00048|M.leprae_Br4923 CTTTPNG----EVASPMPDWSEQLPPNPPAASKSPLPPMPIGSSVQPPPA
:: : * : * . .
Mb3447c|M.bovis_AF2122/97 ------RARRSLAAVGSVAAALLVLS---------------------GFG
Rv3413c|M.tuberculosis_H37Rv ------RARRSLAAVGSVAAALLVLS---------------------GFG
MMAR_1135|M.marinum_M ------RSRRAWAAIGSVAATLLALS---------------------GLG
MUL_0898|M.ulcerans_Agy99 ------RSRRAWAAIGSVAATLLALS---------------------GLG
MAV_4358|M.avium_104 ------RGHRGLAVVGSVAATLMLLS---------------------GFG
Mvan_1509|M.vanbaalenii_PYR-1 -----PRRRLSLAVIGSAAAAVLAIG---------------------GVG
Mflv_4911|M.gilvum_PYR-GCK A----PRRRFSLAVVGSAAAAVLAIG---------------------GFG
TH_3373|M.thermoresistible__bu GGAPRPGRRFSLTVVGSAAAAVICLG---------------------GFG
MSMEG_1600|M.smegmatis_MC2_155 ------RPRLPLALVGSAAAAVLCLG---------------------GFG
MAB_3723c|M.abscessus_ATCC_199 ---------MLATTVGSAAAVTLLFG---------------------GFG
MLBr_00048|M.leprae_Br4923 SSESPRAPMPVSAPPRSPAASLMPISEPPQWPPAEAPEHQFAKAEPPSVP
: * ** : :. ..
Mb3447c|M.bovis_AF2122/97 AVVADARPGDLLYGLHAMMFNRSR--------------------------
Rv3413c|M.tuberculosis_H37Rv AVVADARPGDLLYGLHAMMFNRSR--------------------------
MMAR_1135|M.marinum_M AVVADARPGDLLYGLHAMLFNEPR--------------------------
MUL_0898|M.ulcerans_Agy99 AVVADARPGDLLYGLHAMLFNEPR--------------------------
MAV_4358|M.avium_104 AMVVEARPGSTLYGLHAMFFDQPR--------------------------
Mvan_1509|M.vanbaalenii_PYR-1 AVVAGSGPGDALYGLRTMLFGEQA--------------------------
Mflv_4911|M.gilvum_PYR-GCK AVVAGSGPGDALYGLRTMLFGEQV--------------------------
TH_3373|M.thermoresistible__bu ALVAGAGPGDPLYGLRTMLFGD----------------------------
MSMEG_1600|M.smegmatis_MC2_155 AAVYGSSPGDALYGLRGMIFGEQ---------------------------
MAB_3723c|M.abscessus_ATCC_199 AAVYQSHPGDALYGLRTSLFGAPP--------------------------
MLBr_00048|M.leprae_Br4923 IPINEPSPAKPATPMPMTPIDGSQRTPVTSPEPSLAEFEAQPPATPKPSL
: . *.. : :.
Mb3447c|M.bovis_AF2122/97 ------------------VSD-DQIVLSAKANLAKVEQMIAQGQWAEAQD
Rv3413c|M.tuberculosis_H37Rv ------------------VSD-DQIVLSAKANLAKVEQMIAQGQWAEAQD
MMAR_1135|M.marinum_M ------------------VSE-DQIMLSAKADLAKAEQMIAQGQWDQAES
MUL_0898|M.ulcerans_Agy99 ------------------VSE-DQIMLSAKADLAKAEQMIAQGQWDQAES
MAV_4358|M.avium_104 ------------------VNEKDQVMLAAKADLAKVAESIDKGQWDQART
Mvan_1509|M.vanbaalenii_PYR-1 ------------------QTRDDAVILAAQTEMQQVQQLIEQGDWAGAQA
Mflv_4911|M.gilvum_PYR-GCK ------------------QMRDDAVILAAQTEMQQVQQLIEQGDWQQAQA
TH_3373|M.thermoresistible__bu ------------------VVRDDPVVLAAQTQLAEVEQLIAQGDWEAAQE
MSMEG_1600|M.smegmatis_MC2_155 ------------------ATRDVQVELAS-TELEQVQQLIEQGDWQAAQQ
MAB_3723c|M.abscessus_ATCC_199 ------------------AVRTDPVVLSAQTELAQVEKLISQGDWEEAQQ
MLBr_00048|M.leprae_Br4923 LPRPMSSPPEAPRPSANQHSRHARRGHHHRDETQQANPASATEPMIAPRA
: :. ..
Mb3447c|M.bovis_AF2122/97 ELAEVSSTVQAVTDGSRRQDLINEVNLLNTKVETRDPNATLR----PGSP
Rv3413c|M.tuberculosis_H37Rv ELAEVSSTVQAVTDGSRRQDLINEVNLLNTKVETRDPNATLR----PGSP
MMAR_1135|M.marinum_M QLAEVSSTLQTVNDGSRRQHLLNELNQLNTKVEKRDPNATLP----AGGP
MUL_0898|M.ulcerans_Agy99 QLAEVSSTLQTVNDGSRRQHLLNELNQLNTKVEKRDPNATLP----AGGP
MAV_4358|M.avium_104 QLTEVSSLVASIDDPATKQDLMTQLNLLNAKVDTRNPNATLP----AAAP
Mvan_1509|M.vanbaalenii_PYR-1 KLEAVTTTVATVADVERKQELVTQWQELTVKVEAQDPVATVP----PGSP
Mflv_4911|M.gilvum_PYR-GCK KLEAVTTTVATVDDVAQKEELIAQWQELTVKVEAQDPVATVP----PGAP
TH_3373|M.thermoresistible__bu RLQAVTTTVATVGDETRKQELVAEWQELSVKVESRNPDATVP----PDAP
MSMEG_1600|M.smegmatis_MC2_155 KLQTLTTTVATVNDEAQKQQLVTQWQQLSVKVENQDPNATVA----PDAP
MAB_3723c|M.abscessus_ATCC_199 QLGVAAARVNEVGDAQQKAELASRVQQAEVRIDAKDPQATVPPEMVTETP
MLBr_00048|M.leprae_Br4923 RTAELRQAPHAAAEPAPTQHLTRPDGLVSHRTALHDSTATSAIGVQTGRS
. : .* : ::. ** . .
Mb3447c|M.bovis_AF2122/97 SNPAA----------------------------------------PGSVG
Rv3413c|M.tuberculosis_H37Rv SNPAA----------------------------------------PGSVG
MMAR_1135|M.marinum_M PQSGP----------------------------------------TGVLA
MUL_0898|M.ulcerans_Agy99 PQSGP----------------------------------------TGVLA
MAV_4358|M.avium_104 S-------------------------------------------------
Mvan_1509|M.vanbaalenii_PYR-1 LPTFPDVPVAVLDPGTSSETTSTAPSSETTSPTS-PSETTSPTSPSETTS
Mflv_4911|M.gilvum_PYR-GCK LPTFPELPAAVLDQATTSSETTAGTTSDTTAPSSETTAPSSETTGPSSET
TH_3373|M.thermoresistible__bu PVTLP-----VIDPATSTEPTEPGTPSTEPAEPGEPTEPGDPDMPVDGTE
MSMEG_1600|M.smegmatis_MC2_155 PPVFPEVTITPPAP-TDTSAVETTPGSATPSEPTSPGESATPSDTSDTSE
MAB_3723c|M.abscessus_ATCC_199 RIMLSPPSIAPITSTTTTSTTSTTSASTTTSDSTSASTSTTETSGSASPS
MLBr_00048|M.leprae_Br4923 TGAKKPSKVVAKRGWRHWVHTVTRINLGLSPDERYELDLRTRVRRPPRGS
Mb3447c|M.bovis_AF2122/97 ------NSWTPLAPVVEPPTPP--------TPASAAEPSMSAGVSESPMP
Rv3413c|M.tuberculosis_H37Rv ------NSWTPLAPVVEPPTPP--------TPASAAEPSMSAGVSESPMP
MMAR_1135|M.marinum_M PQVPPGNSLTPLVPETVSPVPPNESGAPESAPAPSASPTTTGAKPSASLP
MUL_0898|M.ulcerans_Agy99 PQVPPGNSLTPLAPETVSPVPPNESGAPESAPAPSASPTTTGAKPSASLP
MAV_4358|M.avium_104 -----------MAPSVAVPAAP--------PPAASIAP--TPAAPPAPLS
Mvan_1509|M.vanbaalenii_PYR-1 PTSP--SETTSPAPSSETTSAPTSSP--SPTPSTAPTTTSVGAAPPSSSA
Mflv_4911|M.gilvum_PYR-GCK TTAP--SETTGPAPTTTAPTSAPTTT--APAPSTTP-TTSVGQTR-SSAA
TH_3373|M.thermoresistible__bu PTSPGTEPTAGPDQPTVPPTVGPTSEPATSEPAMTAPTTTVPTSAPGSAV
MSMEG_1600|M.smegmatis_MC2_155 PSSE-TTVPSSPTPSTAPSSSVPTAT--SQTPTSTQVPTSTPTSSAAVQL
MAB_3723c|M.abscessus_ATCC_199 TSSSTSTSATASTSVTSVPTSTPTTVTITTTPPSSAATITSTPASATETT
MLBr_00048|M.leprae_Br4923 YQIGILGLKGGAGKTTVTVTLGSMFARVRNDRILVVDADTSCGNLADRAG
.
Mb3447c|M.bovis_AF2122/97 NSTSTVAASPSTPSSKPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH-
Rv3413c|M.tuberculosis_H37Rv NSTSTVAASPSTPSSKPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH-
MMAR_1135|M.marinum_M PAGATATSPAPTSVPTPPVSAVVPGETPADTSVVAPGSPAAAGVAATGAG
MUL_0898|M.ulcerans_Agy99 PAGATATSPAPTSVPTPPVSAVVPGETPADTSVVAPGSPAAAGVAAPGPA
MAV_4358|M.avium_104 P------APVSTPSPSPSVG-----------KHHHHGQPPAVAPVNPNQ-
Mvan_1509|M.vanbaalenii_PYR-1 PATTTPTSTTATRAPSATSTTVVQSATTTSAPLSTSSSVAAPPTPTPSPS
Mflv_4911|M.gilvum_PYR-GCK PSTPPSSAPTSTTVVLQSTTTSAAAPTTSAAPTTAAPTTAAPTTAVPTTP
TH_3373|M.thermoresistible__bu RTTTSAPTTATTTSGSTTAGPTAGGPTSSGPATGPTSVPREPGAGAGTTE
MSMEG_1600|M.smegmatis_MC2_155 PSPVEEEEPAEPQPTSVPQAPTS-APAVPAEPSGPSGDPARPPVTATTTV
MAB_3723c|M.abscessus_ATCC_199 TAPSVSTAPTTSVPGVTASTTVPPTASIVTVPTTPEGVTIVTTRPGVVNT
MLBr_00048|M.leprae_Br4923 RFSEANIADLLADKDVKSYNDIRTHTSVNAVNLEVLPAAEYSTAQHALSG
.
Mb3447c|M.bovis_AF2122/97 --------------------------------------------------
Rv3413c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1135|M.marinum_M --------------------------------------------------
MUL_0898|M.ulcerans_Agy99 KLAAPGDATNPGSPVVQTSGQPEPVEPAPAGPVS----------------
MAV_4358|M.avium_104 --------------------------------------------------
Mvan_1509|M.vanbaalenii_PYR-1 PTPTPAPTVDEES------------VPSPTAPALPTTTTPIILLPVPGEA
Mflv_4911|M.gilvum_PYR-GCK SAVETTPAVEEET------------PPSPVAPVTTTTP----VLPLPGE-
TH_3373|M.thermoresistible__bu PTAPAARAGEDGVGGDGTVGGDGAFAEETVGEVPQLTATTTVVLPQSGAA
MSMEG_1600|M.smegmatis_MC2_155 TLPTQAGPAQGPNGRGNGPGNGAKPAEPAQPKAPEQPAVQIPLLPGMGGN
MAB_3723c|M.abscessus_ATCC_199 PVITAPTTIEAPVPITRTPDNPAPAYQAPVNSPGSGNLHGYPGSGGNAGS
MLBr_00048|M.leprae_Br4923 EDWNFAAATVSKYYNVMLADCGVGLFDPVTRGVLSTASGVVIVTSTSVDA
Mb3447c|M.bovis_AF2122/97 --------------------------------------------------
Rv3413c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1135|M.marinum_M --------------------------------------------------
MUL_0898|M.ulcerans_Agy99 --------------------------------------------------
MAV_4358|M.avium_104 --------------------------------------------------
Mvan_1509|M.vanbaalenii_PYR-1 G-------------------------------------------------
Mflv_4911|M.gilvum_PYR-GCK --------------------------------------------------
TH_3373|M.thermoresistible__bu DAAGD---------------------------------------------
MSMEG_1600|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 GSDGPSRHMPAMTSVPVAPANPGSGSANQGSGSGSHTDE-----------
MLBr_00048|M.leprae_Br4923 ARQAAIALDWLRHNGYQDLLSRACVVINHVMPKEPNIASKDLVQQFEQQI
Mb3447c|M.bovis_AF2122/97 --------------------------------------------------
Rv3413c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1135|M.marinum_M --------------------------------------------------
MUL_0898|M.ulcerans_Agy99 --------------------------------------------------
MAV_4358|M.avium_104 --------------------------------------------------
Mvan_1509|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4911|M.gilvum_PYR-GCK --------------------------------------------------
TH_3373|M.thermoresistible__bu --------------------------------------------------
MSMEG_1600|M.smegmatis_MC2_155 --------------------------------------------------
MAB_3723c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00048|M.leprae_Br4923 QPGRVVVLPWDKHIAAGTEIRLDRLDPLYRRRILELAAALSDDFERAGRH