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TVPESLDEFARTDLLLDALAQRRPVPRGQVEDPDDPDFQMLTTLLEDWRDNLRWPPASALVTPEEAVNAL RAGLAERRRGHRGLAVVGSVAATLMLLSGFGAMVVEARPGSTLYGLHAMFFDQPRVNEKDQVMLAAKADL AKVAESIDKGQWDQARTQLTEVSSLVASIDDPATKQDLMTQLNLLNAKVDTRNPNATLPAAAPSMAPSVA VPAAPPPAASIAPTPAAPPAPLSPAPVSTPSPSPSVGKHHHHGQPPAVAPVNPNQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4358 | - | - | 100% (266) | hypothetical protein MAV_4358 |
| M. avium 104 | MAV_4824 | - | 1e-06 | 43.48% (69) | hypothetical protein MAV_4824 |
| M. avium 104 | MAV_1296 | - | 2e-06 | 42.11% (76) | hypothetical protein MAV_1296 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3447c | - | 8e-65 | 49.14% (291) | hypothetical protein Mb3447c |
| M. gilvum PYR-GCK | Mflv_4911 | - | 8e-36 | 34.09% (308) | hypothetical protein Mflv_4911 |
| M. tuberculosis H37Rv | Rv3413c | - | 8e-65 | 49.14% (291) | hypothetical protein Rv3413c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3723c | - | 9e-28 | 31.93% (238) | hypothetical protein MAB_3723c |
| M. marinum M | MMAR_1135 | - | 2e-65 | 52.67% (262) | hypothetical protein MMAR_1135 |
| M. smegmatis MC2 155 | MSMEG_1600 | - | 1e-37 | 39.42% (241) | hypothetical protein MSMEG_1600 |
| M. thermoresistible (build 8) | TH_3373 | - | 6e-36 | 35.51% (276) | PUTATIVE hypothetical protein Mjls_1192 |
| M. ulcerans Agy99 | MUL_0898 | - | 1e-65 | 52.67% (262) | hypothetical protein MUL_0898 |
| M. vanbaalenii PYR-1 | Mvan_1509 | - | 3e-35 | 35.94% (281) | hypothetical protein Mvan_1509 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3447c|M.bovis_AF2122/97 -------MREFGNPL-------GDRPPLDELARTDLLLDALAERE---EV
Rv3413c|M.tuberculosis_H37Rv -------MREFGNPL-------GDRPPLDELARTDLLLDALAERE---EV
MMAR_1135|M.marinum_M -------MPESGFAL-------GDQPGLDEVARTDLLLDALAGRE---RF
MUL_0898|M.ulcerans_Agy99 -------MPESGFTL-------GDQPGLDEVARTDLLLDALAGRE---RF
MAV_4358|M.avium_104 --------------M-------TVPESLDEFARTDLLLDALAQRRPVPRG
Mflv_4911|M.gilvum_PYR-GCK -------MPDFGRRD-----PGGGDPSLTDINRTDQFLDALAAQQ---QP
Mvan_1509|M.vanbaalenii_PYR-1 -------MPDHGRWN-----SGG-DPSLNEINRTDQFLDALASQQ---PV
TH_3373|M.thermoresistible__bu -------MADFGRWNPNWNPDDGGQPSLQDIHRSEQFIEALSTGR---PV
MSMEG_1600|M.smegmatis_MC2_155 -------MPDFGRWT-----SNGGDPSLNEINRTDRFIEALSLEQ---PV
MAB_3723c|M.abscessus_ATCC_199 MADGRGWFPGQGGWQ-----ENEGPEDLAALRRTNRMIDAIAADL---PV
* . *:: :::*::
Mb3447c|M.bovis_AF2122/97 DFADPRD---DALAALLGQWRDDLRWPPASALVSQDEAVAALRAGVAQRR
Rv3413c|M.tuberculosis_H37Rv DFADPRD---DALAALLGQWRDDLRWPPASALVSQDEAVAALRAGVAQRR
MMAR_1135|M.marinum_M SLNDPDD---DALAALMGEWRDDLRWPPASALVSQNEAVDALILGLSERR
MUL_0898|M.ulcerans_Agy99 SLNDPDD---DALAALMGEWRDDLRWPPASALVSQNEAVDALILGLSERR
MAV_4358|M.avium_104 QVEDPDDPDFQMLTTLLEDWRDNLRWPPASALVTPEEAVNALRAGLAERR
Mflv_4911|M.gilvum_PYR-GCK FVTDRDD---VELAQLLAGWRDDIRETPMGHVVTPLQAEAALDR-VTRPA
Mvan_1509|M.vanbaalenii_PYR-1 YATDRGE---AELAHLLAGWRDDVRETPMGHVMTAEDAAIALGR-VTKP-
TH_3373|M.thermoresistible__bu YANDPGE---DELAYLMAGWRDRARNAPMRATITEQDAVAALQRGLPRPR
MSMEG_1600|M.smegmatis_MC2_155 YSTDPEE---AELAFLLAGWRDDVRQAPMTGIINPREAVVALDRAVARN-
MAB_3723c|M.abscessus_ATCC_199 ATSDSDE---YAVAMMLAAWREDVGREPMPAKPTLGQARNALRDRGGRSR
* : :: :: **: * . :* ** .
Mb3447c|M.bovis_AF2122/97 ------RARRSLAAVGSVAAALLVLSGFGAVVADARPGDLLYGLHAMMFN
Rv3413c|M.tuberculosis_H37Rv ------RARRSLAAVGSVAAALLVLSGFGAVVADARPGDLLYGLHAMMFN
MMAR_1135|M.marinum_M ------RSRRAWAAIGSVAATLLALSGLGAVVADARPGDLLYGLHAMLFN
MUL_0898|M.ulcerans_Agy99 ------RSRRAWAAIGSVAATLLALSGLGAVVADARPGDLLYGLHAMLFN
MAV_4358|M.avium_104 ------RGHRGLAVVGSVAATLMLLSGFGAMVVEARPGSTLYGLHAMFFD
Mflv_4911|M.gilvum_PYR-GCK A----PRRRFSLAVVGSAAAAVLAIGGFGAVVAGSGPGDALYGLRTMLFG
Mvan_1509|M.vanbaalenii_PYR-1 -----PRRRLSLAVIGSAAAAVLAIGGVGAVVAGSGPGDALYGLRTMLFG
TH_3373|M.thermoresistible__bu GGAPRPGRRFSLTVVGSAAAAVICLGGFGALVAGAGPGDPLYGLRTMLFG
MSMEG_1600|M.smegmatis_MC2_155 ------RPRLPLALVGSAAAAVLCLGGFGAAVYGSSPGDALYGLRGMIFG
MAB_3723c|M.abscessus_ATCC_199 ---------MLATTVGSAAAVTLLFGGFGAAVYQSHPGDALYGLRTSLFG
: :**.**. : :.*.** * : **. ****: :*.
Mb3447c|M.bovis_AF2122/97 RSRVSD-DQIVLSAKANLAKVEQMIAQGQWAEAQDELAEVSSTVQAVTDG
Rv3413c|M.tuberculosis_H37Rv RSRVSD-DQIVLSAKANLAKVEQMIAQGQWAEAQDELAEVSSTVQAVTDG
MMAR_1135|M.marinum_M EPRVSE-DQIMLSAKADLAKAEQMIAQGQWDQAESQLAEVSSTLQTVNDG
MUL_0898|M.ulcerans_Agy99 EPRVSE-DQIMLSAKADLAKAEQMIAQGQWDQAESQLAEVSSTLQTVNDG
MAV_4358|M.avium_104 QPRVNEKDQVMLAAKADLAKVAESIDKGQWDQARTQLTEVSSLVASIDDP
Mflv_4911|M.gilvum_PYR-GCK EQVQMRDDAVILAAQTEMQQVQQLIEQGDWQQAQAKLEAVTTTVATVDDV
Mvan_1509|M.vanbaalenii_PYR-1 EQAQTRDDAVILAAQTEMQQVQQLIEQGDWAGAQAKLEAVTTTVATVADV
TH_3373|M.thermoresistible__bu D--VVRDDPVVLAAQTQLAEVEQLIAQGDWEAAQERLQAVTTTVATVGDE
MSMEG_1600|M.smegmatis_MC2_155 EQ-ATRDVQVELAS-TELEQVQQLIEQGDWQAAQQKLQTLTTTVATVNDE
MAB_3723c|M.abscessus_ATCC_199 APPAVRTDPVVLSAQTELAQVEKLISQGDWEEAQQQLGVAAARVNEVGDA
: *:: ::: :. : * :*:* *. .* :: : : *
Mb3447c|M.bovis_AF2122/97 SRRQDLINEVNLLNTKVETRDPNATLR----PGSPSNPAA----------
Rv3413c|M.tuberculosis_H37Rv SRRQDLINEVNLLNTKVETRDPNATLR----PGSPSNPAA----------
MMAR_1135|M.marinum_M SRRQHLLNELNQLNTKVEKRDPNATLP----AGGPPQSGP----------
MUL_0898|M.ulcerans_Agy99 SRRQHLLNELNQLNTKVEKRDPNATLP----AGGPPQSGP----------
MAV_4358|M.avium_104 ATKQDLMTQLNLLNAKVDTRNPNATLP----AAAPS--------------
Mflv_4911|M.gilvum_PYR-GCK AQKEELIAQWQELTVKVEAQDPVATVP----PGAPLPTFPELPAAVLDQA
Mvan_1509|M.vanbaalenii_PYR-1 ERKQELVTQWQELTVKVEAQDPVATVP----PGSPLPTFPDVPVAVLDPG
TH_3373|M.thermoresistible__bu TRKQELVAEWQELSVKVESRNPDATVP----PDAPPVTLP-----VIDPA
MSMEG_1600|M.smegmatis_MC2_155 AQKQQLVTQWQQLSVKVENQDPNATVA----PDAPPPVFPEVTITPPAP-
MAB_3723c|M.abscessus_ATCC_199 QQKAELASRVQQAEVRIDAKDPQATVPPEMVTETPRIMLSPPSIAPITST
: .* . : .::: ::* **: . *
Mb3447c|M.bovis_AF2122/97 ------------------------------PGSVG------NSWTPLAPV
Rv3413c|M.tuberculosis_H37Rv ------------------------------PGSVG------NSWTPLAPV
MMAR_1135|M.marinum_M ------------------------------TGVLAPQVPPGNSLTPLVPE
MUL_0898|M.ulcerans_Agy99 ------------------------------TGVLAPQVPPGNSLTPLAPE
MAV_4358|M.avium_104 ----------------------------------------------MAPS
Mflv_4911|M.gilvum_PYR-GCK TTSSETTAGTTSDTTAPSSETTAPSSETTGPSSETTTAP--SETTGPAPT
Mvan_1509|M.vanbaalenii_PYR-1 TSSETTSTAPSSETTSPTS-PSETTSPTSPSETTSPTSP--SETTSPAPS
TH_3373|M.thermoresistible__bu TSTEPTEPGTPSTEPAEPGEPTEPGDPDMPVDGTEPTSPGTEPTAGPDQP
MSMEG_1600|M.smegmatis_MC2_155 TDTSAVETTPGSATPSEPTSPGESATPSDTSDTSEPSSE-TTVPSSPTPS
MAB_3723c|M.abscessus_ATCC_199 TTTSTTSTTSASTTTSDSTSASTSTTETSGSASPSTSSSTSTSATASTSV
Mb3447c|M.bovis_AF2122/97 VEPPTPP--------TPASAAEPSMSAGVSESPMPNSTSTVAASPSTPSS
Rv3413c|M.tuberculosis_H37Rv VEPPTPP--------TPASAAEPSMSAGVSESPMPNSTSTVAASPSTPSS
MMAR_1135|M.marinum_M TVSPVPPNESGAPESAPAPSASPTTTGAKPSASLPPAGATATSPAPTSVP
MUL_0898|M.ulcerans_Agy99 TVSPVPPNESGAPESAPAPSASPTTTGAKPSASLPPAGATATSPAPTSVP
MAV_4358|M.avium_104 VAVPAAP--------PPAASIAP--TPAAPPAPLSP------APVSTPSP
Mflv_4911|M.gilvum_PYR-GCK TTAPTSAPTTT--APAPSTTP-TTSVGQTR-SSAAPSTPPSSAPTSTTVV
Mvan_1509|M.vanbaalenii_PYR-1 SETTSAPTSSP--SPTPSTAPTTTSVGAAPPSSSAPATTTPTSTTATRAP
TH_3373|M.thermoresistible__bu TVPPTVGPTSEPATSEPAMTAPTTTVPTSAPGSAVRTTTSAPTTATTTSG
MSMEG_1600|M.smegmatis_MC2_155 TAPSSSVPTAT--SQTPTSTQVPTSTPTSSAAVQLPSPVEEEEPAEPQPT
MAB_3723c|M.abscessus_ATCC_199 TSVPTSTPTTVTITTTPPSSAATITSTPASATETTTAPSVSTAPTTSVPG
. *. : . . .
Mb3447c|M.bovis_AF2122/97 KPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH----------------
Rv3413c|M.tuberculosis_H37Rv KPEPGSIDPSLEPADEATNPAGQPAPETPVSPTH----------------
MMAR_1135|M.marinum_M TPPVSAVVPGETPADTSVVAPGSPAAAGVAATGAG---------------
MUL_0898|M.ulcerans_Agy99 TPPVSAVVPGETPADTSVVAPGSPAAAGVAAPGPAKLAAPGDATNPGSPV
MAV_4358|M.avium_104 SPSVG-----------KHHHHGQPPAVAPVNPNQ----------------
Mflv_4911|M.gilvum_PYR-GCK LQSTTTSAAAPTTSAAPTTAAPTTAAPTTAVPTTPSAVETTPAVEEET--
Mvan_1509|M.vanbaalenii_PYR-1 SATSTTVVQSATTTSAPLSTSSSVAAPPTPTPSPSPTPTPAPTVDEES--
TH_3373|M.thermoresistible__bu STTAGPTAGGPTSSGPATGPTSVPREPGAGAGTTEPTAPAARAGEDGVGG
MSMEG_1600|M.smegmatis_MC2_155 SVPQAPTS-APAVPAEPSGPSGDPARPPVTATTTVTLPTQAGPAQGPNGR
MAB_3723c|M.abscessus_ATCC_199 VTASTTVPPTASIVTVPTTPEGVTIVTTRPGVVNTPVITAPTTIEAPVPI
Mb3447c|M.bovis_AF2122/97 --------------------------------------------------
Rv3413c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1135|M.marinum_M --------------------------------------------------
MUL_0898|M.ulcerans_Agy99 VQTSGQPEPVEPAPAGPVS-------------------------------
MAV_4358|M.avium_104 --------------------------------------------------
Mflv_4911|M.gilvum_PYR-GCK ----------PPSPVAPVTTTTP----VLPLPGE----------------
Mvan_1509|M.vanbaalenii_PYR-1 ----------VPSPTAPALPTTTTPIILLPVPGEAG--------------
TH_3373|M.thermoresistible__bu DGTVGGDGAFAEETVGEVPQLTATTTVVLPQSGAADAAGD----------
MSMEG_1600|M.smegmatis_MC2_155 GNGPGNGAKPAEPAQPKAPEQPAVQIPLLPGMGGN---------------
MAB_3723c|M.abscessus_ATCC_199 TRTPDNPAPAYQAPVNSPGSGNLHGYPGSGGNAGSGSDGPSRHMPAMTSV
Mb3447c|M.bovis_AF2122/97 ------------------------
Rv3413c|M.tuberculosis_H37Rv ------------------------
MMAR_1135|M.marinum_M ------------------------
MUL_0898|M.ulcerans_Agy99 ------------------------
MAV_4358|M.avium_104 ------------------------
Mflv_4911|M.gilvum_PYR-GCK ------------------------
Mvan_1509|M.vanbaalenii_PYR-1 ------------------------
TH_3373|M.thermoresistible__bu ------------------------
MSMEG_1600|M.smegmatis_MC2_155 ------------------------
MAB_3723c|M.abscessus_ATCC_199 PVAPANPGSGSANQGSGSGSHTDE