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RIARRETAAVTVGVVLVAAAFVLPRLDLGVKPRRDIGLERFASRAGAAPIFGYWDIHASWGTIAAILLAL AVLVWGPRVARKLSWRVLPLATWATACGWPFSLAMIDGFERGFAGRLTTKDEYLSEVGGVTDIPVMLRTF ASRIVDYQPNSWTTHVSGHPPGALLTFVWLDRIGLGGGAWAGFLCLLVGSSAAAAMVIAVGALAGKHVAR RAAPFVAIAPTAIWIAVSADGYFAGVTAWGITLLAIAVHGGSRFRALWAAGAGLVLGWAIFLSYGLALMG LPALAVLASANHWRTALKALWPAVLAALGVALAFAVAGFWWFDGYTLVQQRYWQGIAHDRPFQYWSWANL ACVVCAIGLGSVAGISRVVDAAAIRRRSGLHLPLLGMVAAILVADLSMLSKAETERIWLPFTVWLTTAPA LLRPRSDRLWLAVNAAGALAVNSIIFTNW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0640 | - | - | 100% (450) | hypothetical protein MUL_0640 |
| M. ulcerans Agy99 | MUL_1212 | - | 8e-05 | 35.40% (113) | transmembrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0555c | - | 0.0 | 76.67% (450) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_0468 | - | 5e-07 | 26.39% (269) | hypothetical protein Mflv_0468 |
| M. tuberculosis H37Rv | Rv0541c | - | 0.0 | 76.89% (450) | integral membrane protein |
| M. leprae Br4923 | MLBr_02529 | - | 1e-05 | 31.51% (146) | hypothetical protein MLBr_02529 |
| M. abscessus ATCC 19977 | MAB_4441 | - | 2e-05 | 30.25% (162) | putative oxidoreductase |
| M. marinum M | MMAR_0887 | - | 0.0 | 99.33% (450) | hypothetical protein MMAR_0887 |
| M. avium 104 | MAV_4603 | - | 0.0 | 72.16% (449) | integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_0999 | - | 1e-172 | 65.64% (454) | integral membrane protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_0891 | - | 1e-177 | 67.18% (451) | putative integral membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0640|M.ulcerans_Agy99 ----------MRIARRETAAVTVGVVLVAAAFVLPRLDLGVK-PRRDIGL
MMAR_0887|M.marinum_M ----------MRIARRETAAVTVGVVLVAAAFVLPRLDLGVK-PRRDIGL
Mb0555c|M.bovis_AF2122/97 ----------MRIGRREGLAVAIGFVLVGAAFVLPRLNLGIK-PRSDIGL
Rv0541c|M.tuberculosis_H37Rv ----------MRIGRREGLAVAIGFVLVGAAFVLPRLNLGIK-PRSDIGL
MAV_4603|M.avium_104 ------------------MAAAVGAALVAAAFLLPRLNLGVR-PRLDVGP
MSMEG_0999|M.smegmatis_MC2_155 ----------MQIGRRELVAVIIAILLVTAAFVVPHLDLGIVTPLINSTP
Mvan_0891|M.vanbaalenii_PYR-1 ----------MPIGRKEAVAVAVGSVLVVAAFVIPHLDLGVVTPLINATP
Mflv_0468|M.gilvum_PYR-GCK MLRGDGPGPARQWSADAVVVGVLAFALGVAAAGRPSLWVDEAGTLSAATR
MLBr_02529|M.leprae_Br4923 --------------MVYVFAEEFCEGPVTSGAVMPIVRVAILADSRLIEM
MAB_4441|M.abscessus_ATCC_1997 ----------MEHAARRIIAGLIAAAAALAVGQLAAAAVAPDSAPFYAVG
. . : . :
MUL_0640|M.ulcerans_Agy99 ---ERFASRAGAAPIFGYWDIHAS-----------WGTIAAILLALAVLV
MMAR_0887|M.marinum_M ---ERFASRAGAAPIFGYWDIHAS-----------WGTIAAILLALAVLV
Mb0555c|M.bovis_AF2122/97 ---ERFATRAGAAPIFGYWDAHVG-----------WGTAPAVLTAVAVVA
Rv0541c|M.tuberculosis_H37Rv ---ERFATRAGAAPIFGYWDAHVG-----------WGTAPAVLTAVAVVA
MAV_4603|M.avium_104 ---ERFATHAGAAPIFGEWLIHAG-----------WGTGPAVALAAAVVA
MSMEG_0999|M.smegmatis_MC2_155 ---AQIYSFADTAPIFGWWNAHVG-----------WGTVPAVLIGAATVW
Mvan_0891|M.vanbaalenii_PYR-1 ---ERLRSFADTAPIFGWWNTHVG-----------AGTIPAFAIGAAAVL
Mflv_0468|M.gilvum_PYR-GCK PVDALWTLVHHVDAVHGFYYLLLRGWFEIVPVTEFWARVPSALMVGVAAA
MLBr_02529|M.leprae_Br4923 ALPTELPLREILPAVKRLVVPAAS-----------DNDSPLAANASLHLS
MAB_4441|M.abscessus_ATCC_1997 NTVVDHTPAAVREWVIGIFGTSDK---------AVLFACLTVIIALLAAL
:
MUL_0640|M.ulcerans_Agy99 WGPRVARKLSWR-------------VLPLATWATACGWPFSLAMIDG-FE
MMAR_0887|M.marinum_M WGPRVARKLSWR-------------VLPLATWATACGWAFSLAMIDG-FE
Mb0555c|M.bovis_AF2122/97 WGPVVAHRLPWR-------------VLTLSTWATAAAWAFSLAMIDG-WQ
Rv0541c|M.tuberculosis_H37Rv WGPVVAHRLPWR-------------VLTLSTWATAAAWAFSLAMIDG-WQ
MAV_4603|M.avium_104 WGPVLAQRLSWR-------------ALTLGSWAVAAGWAFALAMIDG-WQ
MSMEG_0999|M.smegmatis_MC2_155 WGPAVAQRLPWR-------------ALPLVAWVTSALWAFSLAMIDG-WQ
Mvan_0891|M.vanbaalenii_PYR-1 WGPPLAQRLPWR-------------WLPWLSWTVSCAWAFSLAMVDG-WQ
Mflv_0468|M.gilvum_PYR-GCK GTCVLGSRLSGRKVGIAAGVV--FAVLPRTTWAAVEARPYALSMACAVWL
MLBr_02529|M.leprae_Br4923 LAPIGGAPFSLDAS---------LDTVGVVDGDLLALQPVPVGPAAPGIV
MAB_4441|M.abscessus_ATCC_1997 AGLVEGERRYGTVLIGLLGVFGAVAAVTRPAGTFAWIWPSVIAAVAGALV
. : . :.
MUL_0640|M.ulcerans_Agy99 RGFAGRLTTKDEYLSEVGGVTDIP-VMLRTFASRIVDYQPNSWTTHVSGH
MMAR_0887|M.marinum_M RGFAGRLTTKDEYLSEVGGVTDIP-VMLRTFASRIVDYQPNSWTTHVSGH
Mb0555c|M.bovis_AF2122/97 RGFAGRLTTRDEYLWQVPGIADIP-ATLRTFTSRILDFQPNSWVTHVSGH
Rv0541c|M.tuberculosis_H37Rv RGFAGRLTTRDEYLWQVPGIADIP-ATLRTFTSRILDFQPNSWVTHVSGH
MAV_4603|M.avium_104 RGFAGRLTTRDEYLWEVPRVTDIA-AAVRTFSSRIVDYQPHSWTTHVSGH
MSMEG_0999|M.smegmatis_MC2_155 RGFAGRLTARHEYLRQVPSVTDIG-EALRTFSSRILDFQPDSWITHVSGH
Mvan_0891|M.vanbaalenii_PYR-1 RGFAGRLTARHEYLRQVPTVTDIP-EALRTFAGRILDYQPDSWITHVSGH
Mflv_0468|M.gilvum_PYR-GCK TVLFVAAVRRGGRRWWLGYGAALV-GAVTVNVMVVLILAG--HAAMLAAT
MLBr_02529|M.leprae_Br4923 EDIADAAMIFSTARLQSWGPTHIRRGALAATTAVTFAATGLGVTYRAVTG
MAB_4441|M.abscessus_ATCC_1997 LGTLVHRAQSQAVPDRRRFFGTAAVFALGSAGLYWLGTRWSKGTVVAAER
: .
MUL_0640|M.ulcerans_Agy99 PPGALLTFVWLDRIGLGGGAWAGFLCLLVGSSAAAAMVIAVG--------
MMAR_0887|M.marinum_M PPGALLTFVWLDRIGLGGGAWAGFLCLLVGSSAAAAMVIAVG--------
Mb0555c|M.bovis_AF2122/97 PPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVR--------
Rv0541c|M.tuberculosis_H37Rv PPGALLTFVWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVR--------
MAV_4603|M.avium_104 PPGALLTFVWLDRLGLHGGGWAGLLCLLAGSSAAAAVLIGVR--------
MSMEG_0999|M.smegmatis_MC2_155 PPGALLTFVWLDRIGLGGGAWAGLLCLLVGSSAAAAIVVALR--------
Mvan_0891|M.vanbaalenii_PYR-1 PPGALLTFVWLDRIGLGGGAWAGLLCLLAGSSIAAAIVVTVR--------
Mflv_0468|M.gilvum_PYR-GCK RPDRRTVRAWLVTVVVASVALIPLFVVLLSQQAQIAWIWPVGPVTLGQIA
MLBr_02529|M.leprae_Br4923 ALTGLLVVIVIAVLIALGGLVLRSRAARTGLVLSIAALVPIGAVFALAVP
MAB_4441|M.abscessus_ATCC_1997 REATVPAPVAPAPPLPEGIDVKGAVPYITSNTDFYRIDTALRVP------
. . . :
MUL_0640|M.ulcerans_Agy99 ------ALAGKHVARRAAPFVAIAPTAIWIA----VSADGYFAGVTAWGI
MMAR_0887|M.marinum_M ------ALAGEHVARRAAPFVAIAPTAIWIA----VSADGYFAGVTAWGI
Mb0555c|M.bovis_AF2122/97 ------VLASEQMARRTAPFVAVAPTAIWVA----VSADGYFAGVAAWGI
Rv0541c|M.tuberculosis_H37Rv ------VLASEQMARRTAPFVAVAPTAIWIA----VSADGYFAGVAAWGI
MAV_4603|M.avium_104 ------ALADEPTARRAAPFVALAPTAIWVA----VSADGYFAGVAAWGI
MSMEG_0999|M.smegmatis_MC2_155 ------AVSGEATARLAAPFVAVAPTAIWIA----VSADGYFAGVAAWGL
Mvan_0891|M.vanbaalenii_PYR-1 ------ALADEDTARAAAPFVAVAPTAIWIA----VSADGYFAGVAAWGI
Mflv_0468|M.gilvum_PYR-GCK GEQYFPSVYSDSVRAVGPDQQQFSAEQLRVA----MSAWARVAPLIVVIV
MLBr_02529|M.leprae_Br4923 G-----IFGPAQVLLASAGVTAWSLIALIVPGPERVRIVAFFTATVVIGV
MAB_4441|M.abscessus_ATCC_1997 ------QVSTAEWQLNIHGMVDRPRTLMWADLN-AMAATQRAVTLTCVSN
. . : : .
MUL_0640|M.ulcerans_Agy99 TLLAIAVHGGSRFR-----------ALWAAGAGLVLGWAIFLSYGLALMG
MMAR_0887|M.marinum_M TLLAIAVHGGSRFR-----------ALWAAGAGLVLGWAIFLSYGLALMG
Mb0555c|M.bovis_AF2122/97 ALLAVAVHGATRFP-----------ALVAAGAGLLLGWGVFLNYGLVLIV
Rv0541c|M.tuberculosis_H37Rv ALLAVAVHGATRFP-----------ALVAAGAGLLLGWGVFLNYGLVLIV
MAV_4603|M.avium_104 ALLAVAVHRPLRFP-----------ALTAAGAGLLLGWGVFCNYGLMLMG
MSMEG_0999|M.smegmatis_MC2_155 ALLALAVRDSVHRRRVA--------LPTAVGSGLLLGWGIFLNYGLALAA
Mvan_0891|M.vanbaalenii_PYR-1 TLLALAVRGSVRQP-----------VAAAIGSGLLLGWAVFLNYGLVLMA
Mflv_0468|M.gilvum_PYR-GCK IVAALAVRARRRHGALIENPSGTRVLVLGAVAWIVVPTVVLLGYSVLVRP
MLBr_02529|M.leprae_Br4923 AVMLEAGAALLWQLTPLTIGCGLILAALLVTVEAAQLSALWARFPLPVIP
MAB_4441|M.abscessus_ATCC_1997 EIGGNLIGNAVWTG--------FPIKPILESVGVHPDADMLLSKSVDGWT
: : :
MUL_0640|M.ulcerans_Agy99 LPALAVLASAN--------HWRTALKALWPAVLAALGVALAFAVAGFWWF
MMAR_0887|M.marinum_M LPALAVLASAN--------HWRTALKALWPAVLAALGVALAFAVAGFWWF
Mb0555c|M.bovis_AF2122/97 LPGMAVLAAA---------DWRPVLRALGPAVLAALVVAVSFAVAGFSWF
Rv0541c|M.tuberculosis_H37Rv LPGMAVLAAA---------DWRPVLRALGPAVLAALVVAVSFAVAGFSWF
MAV_4603|M.avium_104 LPAAAVLAAAPRPPRDGWTQWRAVLRALGPAALAAIAVAVAFAVAGFYWF
MSMEG_0999|M.smegmatis_MC2_155 LIALAVLITAP--------DWRAALRVAVPAVIAVLAVVAVFLVAGFWWF
Mvan_0891|M.vanbaalenii_PYR-1 FPAVAVLLGAA--------TWQAAVRTLVPAVVAALAVVAVFAAAGFWWF
Mflv_0468|M.gilvum_PYR-GCK LYQPHYLTFTTP-----ALALLIGLCVVTLCRDDTRRLTATLAVLAVAAA
MLBr_02529|M.leprae_Br4923 APGDPTPSAPSFQVLEDLPRRVRISSAHQSGFIAAATLLSMLGSVAIALR
MAB_4441|M.abscessus_ATCC_1997 AGTPLQVLTDGR----DAILAIAMNGTPLPVEHGYPVRQVVPGLYGYVSA
. .
MUL_0640|M.ulcerans_Agy99 DGYTLVQQRYWQG-IAHDRPFQYWSWANLACVVCAIGLG-SVAGISRVVD
MMAR_0887|M.marinum_M DGYTLVQQRYWQG-IAHDRPFQYWSWANLACVVCAIGLG-SVAGISRVVD
Mb0555c|M.bovis_AF2122/97 DGYTLVQQRYWQG-IAKDRPFGYWSWANLACVVCAIGLG-SVAGLSRVFD
Rv0541c|M.tuberculosis_H37Rv DGYTLVQQRYWQG-IAKDRPFGYWSWANLACVVCAIGLG-SVAGLSRVFD
MAV_4603|M.avium_104 DGYTLVQQRYWQG-IAKDRPFQYWSWANLACVVCAIGLG-GVAGVGRVFD
MSMEG_0999|M.smegmatis_MC2_155 DGYTLVQERYWQG-IANNRPFQYWSWANLASVVCAIGLG-SVAGIGRVFD
Mvan_0891|M.vanbaalenii_PYR-1 DGYLLVQERYWQG-IANDRPFQYWGWANFASVVCAIGLG-SVAGLGRVFD
Mflv_0468|M.gilvum_PYR-GCK PNYLAQRGPYAKYGSDYSQVAELLARESGPRDCVVVDDR-TAPSVPHAIE
MLBr_02529|M.leprae_Br4923 PEAVSSVGWYLVAATAVAATLRARVWDSVACKAWLLAQPYLVASVLLGLY
MAB_4441|M.abscessus_ATCC_1997 TKWVVDWEITRFDKADAYWTIRGWSARGPIKTGCRIDTPRTGDRLGTGTQ
. : :
MUL_0640|M.ulcerans_Agy99 AAAIRRRSGLHLPLLGMVAA--ILVADLSMLSKAETERIWLPFTVWLTTA
MMAR_0887|M.marinum_M AAAIRRRSGLHLLLLGMVAA--ILVADLSMLSKAETERIWLPFTVWLTTA
Mb0555c|M.bovis_AF2122/97 RAAISRRSGCHLLLLAVLAA--IALADLSMLSKAETERIWLPFTIWLTAA
Rv0541c|M.tuberculosis_H37Rv RAAISRRSGCHLLLLAVLAA--IALADLSMLSKAETERIWLPFTIWLTAA
MAV_4603|M.avium_104 RAAIRRRSGFPLLLLAVLAA--AACADLSMLSKAEVERIWLPFTIWLTAA
MSMEG_0999|M.smegmatis_MC2_155 IKAARRNPGLPMLVIGALLA--ITFADLSMLSKAETERIWLPFTVWLTAA
Mvan_0891|M.vanbaalenii_PYR-1 IAAIKRRSGLHLLVLGALLA--IVVADLSRLSKAETERIWLPFTVWLVAS
Mflv_0468|M.gilvum_PYR-GCK GARRAHPVAARDLGLAPPER--TALFSARDPLGVRADDLRTCAVLWTIGD
MLBr_02529|M.leprae_Br4923 TATGRYVAASAALLVLVVVV--LAWAVVALNPRIASSDSYSLPLRRLLGM
MAB_4441|M.abscessus_ATCC_1997 IVAGTAWAQHRGIATVEVQIDDGPWLPARLAPEYSVDTWRQWWFAWQATA
.
MUL_0640|M.ulcerans_Agy99 PALLRPRSDRLWLAVNAAGALAVNSIIFTNW------------
MMAR_0887|M.marinum_M PALLRPRSDRLWLAVNAAGALAVNSIIFTNW------------
Mb0555c|M.bovis_AF2122/97 PALLPPRSHRLWLAVNAAGALLLNSIIFTNW------------
Rv0541c|M.tuberculosis_H37Rv PALLPPRSHRLWLAVNAAGALLLNSIIFTNW------------
MAV_4603|M.avium_104 AALLPVRTHRIWLALNAVGALAVNTIILTHW------------
MSMEG_0999|M.smegmatis_MC2_155 GALLPPRSHRWWLGLNVAGALALNHLILTNW------------
Mvan_0891|M.vanbaalenii_PYR-1 TALLPPRSARWWLALNVIGALAINHLILTNW------------
Mflv_0468|M.gilvum_PYR-GCK AAPGSPADAPVDRVARAQGFVPAERWRFNQTEVVRSVPAGARS
MLBr_02529|M.leprae_Br4923 VASGLDAS----LIPAMAYLVSLFSWVLNR-------------
MAB_4441|M.abscessus_ATCC_1997 GEHIITARATDGTGAVQTDQIASPVPDGATGYPKRLVTVAA--
: