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PIGRKEAVAVAVGSVLVVAAFVIPHLDLGVVTPLINATPERLRSFADTAPIFGWWNTHVGAGTIPAFAIG AAAVLWGPPLAQRLPWRWLPWLSWTVSCAWAFSLAMVDGWQRGFAGRLTARHEYLRQVPTVTDIPEALRT FAGRILDYQPDSWITHVSGHPPGALLTFVWLDRIGLGGGAWAGLLCLLAGSSIAAAIVVTVRALADEDTA RAAAPFVAVAPTAIWIAVSADGYFAGVAAWGITLLALAVRGSVRQPVAAAIGSGLLLGWAVFLNYGLVLM AFPAVAVLLGAATWQAAVRTLVPAVVAALAVVAVFAAAGFWWFDGYLLVQERYWQGIANDRPFQYWGWAN FASVVCAIGLGSVAGLGRVFDIAAIKRRSGLHLLVLGALLAIVVADLSRLSKAETERIWLPFTVWLVAST ALLPPRSARWWLALNVIGALAINHLILTNW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0891 | - | - | 100% (451) | putative integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0555c | - | 1e-179 | 68.07% (451) | integral membrane protein |
| M. gilvum PYR-GCK | Mflv_0468 | - | 9e-07 | 28.57% (245) | hypothetical protein Mflv_0468 |
| M. tuberculosis H37Rv | Rv0541c | - | 1e-179 | 68.29% (451) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0962 | - | 6e-05 | 31.34% (134) | cation-transporting ATPase E |
| M. marinum M | MMAR_0887 | - | 1e-179 | 67.85% (451) | hypothetical protein MMAR_0887 |
| M. avium 104 | MAV_4603 | - | 1e-176 | 67.41% (451) | integral membrane protein |
| M. smegmatis MC2 155 | MSMEG_0999 | - | 0.0 | 77.65% (452) | integral membrane protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0640 | - | 1e-177 | 67.18% (451) | hypothetical protein MUL_0640 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0891|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0999|M.smegmatis_MC2_155 --------------------------------------------------
Mb0555c|M.bovis_AF2122/97 --------------------------------------------------
Rv0541c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4603|M.avium_104 --------------------------------------------------
MMAR_0887|M.marinum_M --------------------------------------------------
MUL_0640|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0468|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0962|M.abscessus_ATCC_1997 MATIEGLTISGLTAAEVAERVAQGKTNDVPSRAARSVSDIVRANVFTRIN
Mvan_0891|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_0999|M.smegmatis_MC2_155 --------------------------------------------------
Mb0555c|M.bovis_AF2122/97 --------------------------------------------------
Rv0541c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_4603|M.avium_104 --------------------------------------------------
MMAR_0887|M.marinum_M --------------------------------------------------
MUL_0640|M.ulcerans_Agy99 --------------------------------------------------
Mflv_0468|M.gilvum_PYR-GCK ------------------------------------------MLRGDGPG
MAB_0962|M.abscessus_ATCC_1997 AILGVLLIIVLSTGSIINGAFGLLIIANSAVGIIQELRAKQILDKLAIVG
Mvan_0891|M.vanbaalenii_PYR-1 --MPIGRKEAVAVAVG-----------------SVLVVAAFVIPHLDLGV
MSMEG_0999|M.smegmatis_MC2_155 --MQIGRRELVAVIIA-----------------ILLVTAAFVVPHLDLGI
Mb0555c|M.bovis_AF2122/97 --MRIGRREGLAVAIG-----------------FVLVGAAFVLPRLNLG-
Rv0541c|M.tuberculosis_H37Rv --MRIGRREGLAVAIG-----------------FVLVGAAFVLPRLNLG-
MAV_4603|M.avium_104 ----------MAAAVG-----------------AALVAAAFLLPRLNLG-
MMAR_0887|M.marinum_M --MRIARRETAAVTVG-----------------VVLVAAAFVLPRLDLG-
MUL_0640|M.ulcerans_Agy99 --MRIARRETAAVTVG-----------------VVLVAAAFVLPRLDLG-
Mflv_0468|M.gilvum_PYR-GCK PARQWSADAVVVGVLA-----------------FALGVAAAGRPSLWVDE
MAB_0962|M.abscessus_ATCC_1997 QTRPLVRRDGAATALAPNEVVLDDIIELGPGDQIVVDGEVIEESALEIDE
. :. : . . * :.
Mvan_0891|M.vanbaalenii_PYR-1 ---------------------------VTPLINATP---ERLRSFADTAP
MSMEG_0999|M.smegmatis_MC2_155 ---------------------------VTPLINSTP---AQIYSFADTAP
Mb0555c|M.bovis_AF2122/97 ---------------------------IKPRSDIGL---ERFATRAGAAP
Rv0541c|M.tuberculosis_H37Rv ---------------------------IKPRSDIGL---ERFATRAGAAP
MAV_4603|M.avium_104 ---------------------------VRPRLDVGP---ERFATHAGAAP
MMAR_0887|M.marinum_M ---------------------------VKPRRDIGL---ERFASRAGAAP
MUL_0640|M.ulcerans_Agy99 ---------------------------VKPRRDIGL---ERFASRAGAAP
Mflv_0468|M.gilvum_PYR-GCK ---------------------------AGTLSAATRPVDALWTLVHHVDA
MAB_0962|M.abscessus_ATCC_1997 SLLTGEADAIEKTIGSQVLSGSFVVAGSGAYRATKVGREAYAAKLAEEAS
. .
Mvan_0891|M.vanbaalenii_PYR-1 IFGWWNTHVG-----------AGTIPAFAIGAAAVLWGPPLAQRLPWR--
MSMEG_0999|M.smegmatis_MC2_155 IFGWWNAHVG-----------WGTVPAVLIGAATVWWGPAVAQRLPWR--
Mb0555c|M.bovis_AF2122/97 IFGYWDAHVG-----------WGTAPAVLTAVAVVAWGPVVAHRLPWR--
Rv0541c|M.tuberculosis_H37Rv IFGYWDAHVG-----------WGTAPAVLTAVAVVAWGPVVAHRLPWR--
MAV_4603|M.avium_104 IFGEWLIHAG-----------WGTGPAVALAAAVVAWGPVLAQRLSWR--
MMAR_0887|M.marinum_M IFGYWDIHAS-----------WGTIAAILLALAVLVWGPRVARKLSWR--
MUL_0640|M.ulcerans_Agy99 IFGYWDIHAS-----------WGTIAAILLALAVLVWGPRVARKLSWR--
Mflv_0468|M.gilvum_PYR-GCK VHGFYYLLLRGWFEIVPVTEFWARVPSALMVGVAAAGTCVLGSRLSGRKV
MAB_0962|M.abscessus_ATCC_1997 KFTLVHSELRNG----INKILQFITYLLLPAGALIIYTQLFTTDDSWQES
. . . . :
Mvan_0891|M.vanbaalenii_PYR-1 ---------WLPWLSWTVSCAWAFSLAMVDG-WQRGFAGRLTARHEYLRQ
MSMEG_0999|M.smegmatis_MC2_155 ---------ALPLVAWVTSALWAFSLAMIDG-WQRGFAGRLTARHEYLRQ
Mb0555c|M.bovis_AF2122/97 ---------VLTLSTWATAAAWAFSLAMIDG-WQRGFAGRLTTRDEYLWQ
Rv0541c|M.tuberculosis_H37Rv ---------VLTLSTWATAAAWAFSLAMIDG-WQRGFAGRLTTRDEYLWQ
MAV_4603|M.avium_104 ---------ALTLGSWAVAAGWAFALAMIDG-WQRGFAGRLTTRDEYLWE
MMAR_0887|M.marinum_M ---------VLPLATWATACGWAFSLAMIDG-FERGFAGRLTTKDEYLSE
MUL_0640|M.ulcerans_Agy99 ---------VLPLATWATACGWPFSLAMIDG-FERGFAGRLTTKDEYLSE
Mflv_0468|M.gilvum_PYR-GCK GIAAGVVFAVLPRTTWAAVEARPYALSMACAVWLTVLFVAAVRRGGRRWW
MAB_0962|M.abscessus_ATCC_1997 VLRMVGALVPMVPEGLVLMTSIAFAVGVIRLGRRQCLVQELPAIEGLARV
: . .:::.: :
Mvan_0891|M.vanbaalenii_PYR-1 VPTVTDIPEALRTFAGRILDYQPD---------SWITHVSGHPPGALLTF
MSMEG_0999|M.smegmatis_MC2_155 VPSVTDIGEALRTFSSRILDFQPD---------SWITHVSGHPPGALLTF
Mb0555c|M.bovis_AF2122/97 VPGIADIPATLRTFTSRILDFQPN---------SWVTHVSGHPPGALLTF
Rv0541c|M.tuberculosis_H37Rv VPGIADIPATLRTFTSRILDFQPN---------SWVTHVSGHPPGALLTF
MAV_4603|M.avium_104 VPRVTDIAAAVRTFSSRIVDYQPH---------SWTTHVSGHPPGALLTF
MMAR_0887|M.marinum_M VGGVTDIPVMLRTFASRIVDYQPN---------SWTTHVSGHPPGALLTF
MUL_0640|M.ulcerans_Agy99 VGGVTDIPVMLRTFASRIVDYQPN---------SWTTHVSGHPPGALLTF
Mflv_0468|M.gilvum_PYR-GCK LGYGAALVGAVTVNVMVVLILAG-----------HAAMLAATRPDRRTVR
MAB_0962|M.abscessus_ATCC_1997 DTVCADKTGTLTENGMRLADVHFPDRDGDEDALAVLAQLAADDPRPNASI
: : : : ::. *
Mvan_0891|M.vanbaalenii_PYR-1 VWLDRIGLGGGAWAGLLCLLAGSSIAAAIVVTVR----------------
MSMEG_0999|M.smegmatis_MC2_155 VWLDRIGLGGGAWAGLLCLLVGSSAAAAIVVALR----------------
Mb0555c|M.bovis_AF2122/97 VWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVR----------------
Rv0541c|M.tuberculosis_H37Rv VWLDRIGLRGGGWAGLVCLLVGSSAAAAVLIAVR----------------
MAV_4603|M.avium_104 VWLDRLGLHGGGWAGLLCLLAGSSAAAAVLIGVR----------------
MMAR_0887|M.marinum_M VWLDRIGLGGGAWAGFLCLLVGSSAAAAMVIAVG----------------
MUL_0640|M.ulcerans_Agy99 VWLDRIGLGGGAWAGFLCLLVGSSAAAAMVIAVG----------------
Mflv_0468|M.gilvum_PYR-GCK AWLVTVVVASVALIPLFVVLLSQQAQIAWIWPVGP---VTLGQIAGEQYF
MAB_0962|M.abscessus_ATCC_1997 AAIAEAYDTPPGWETTAIAPFSSAKKWSGASYGEHGNWVIGAPDVLLDPA
. : . .. :
Mvan_0891|M.vanbaalenii_PYR-1 -ALADEDTARAAAPFVAVAPTAIWIAVSADGYFAGVAAWGITLLALAVRG
MSMEG_0999|M.smegmatis_MC2_155 -AVSGEATARLAAPFVAVAPTAIWIAVSADGYFAGVAAWGLALLALAVRD
Mb0555c|M.bovis_AF2122/97 -VLASEQMARRTAPFVAVAPTAIWVAVSADGYFAGVAAWGIALLAVAVHG
Rv0541c|M.tuberculosis_H37Rv -VLASEQMARRTAPFVAVAPTAIWIAVSADGYFAGVAAWGIALLAVAVHG
MAV_4603|M.avium_104 -ALADEPTARRAAPFVALAPTAIWVAVSADGYFAGVAAWGIALLAVAVHR
MMAR_0887|M.marinum_M -ALAGEHVARRAAPFVAIAPTAIWIAVSADGYFAGVTAWGITLLAIAVHG
MUL_0640|M.ulcerans_Agy99 -ALAGKHVARRAAPFVAIAPTAIWIAVSADGYFAGVTAWGITLLAIAVHG
Mflv_0468|M.gilvum_PYR-GCK PSVYSDSVRAVGPDQQQFSAEQLRVAMSAWARVAPLIVVIVIVAALAVRA
MAB_0962|M.abscessus_ATCC_1997 DAIATAAEEIGARGLRVLLLASAELSVDDAHAPGAVTPRALVVLEQKIRP
: . :::. . : : : ::
Mvan_0891|M.vanbaalenii_PYR-1 SVRQP--------------------VAAAIGSGLLLGWAVFLNYGLVLMA
MSMEG_0999|M.smegmatis_MC2_155 SVHRRRVA-----------------LPTAVGSGLLLGWGIFLNYGLALAA
Mb0555c|M.bovis_AF2122/97 ATRFP--------------------ALVAAGAGLLLGWGVFLNYGLVLIV
Rv0541c|M.tuberculosis_H37Rv ATRFP--------------------ALVAAGAGLLLGWGVFLNYGLVLIV
MAV_4603|M.avium_104 PLRFP--------------------ALTAAGAGLLLGWGVFCNYGLMLMG
MMAR_0887|M.marinum_M GSRFR--------------------ALWAAGAGLVLGWAIFLSYGLALMG
MUL_0640|M.ulcerans_Agy99 GSRFR--------------------ALWAAGAGLVLGWAIFLSYGLALMG
Mflv_0468|M.gilvum_PYR-GCK RRRHGALIEN---------PSGTRVLVLGAVAWIVVPTVVLLGYSVLVRP
MAB_0962|M.abscessus_ATCC_1997 DARETLDYFASQHVSIKVISGDNAVSVSAVAQTLGLTGAAVDARTLPTDT
: . : : . :
Mvan_0891|M.vanbaalenii_PYR-1 FPAVAVLLGAA--------TWQAAVRTLV---------------------
MSMEG_0999|M.smegmatis_MC2_155 LIALAVLITAP--------DWRAALRVAV---------------------
Mb0555c|M.bovis_AF2122/97 LPGMAVLAAA---------DWRPVLRALG---------------------
Rv0541c|M.tuberculosis_H37Rv LPGMAVLAAA---------DWRPVLRALG---------------------
MAV_4603|M.avium_104 LPAAAVLAAAPRPPRDGWTQWRAVLRALG---------------------
MMAR_0887|M.marinum_M LPALAVLASAN--------HWRTALKALW---------------------
MUL_0640|M.ulcerans_Agy99 LPALAVLASAN--------HWRTALKALW---------------------
Mflv_0468|M.gilvum_PYR-GCK LYQPHYLTFTTP-----ALALLIGLCVVT---------------------
MAB_0962|M.abscessus_ATCC_1997 DKLAATLADATTFGRVRPDQKRAMVKALQSHGHTVAMTGDGVNDVLALKD
* : : .
Mvan_0891|M.vanbaalenii_PYR-1 --------PAVVAALAVVAVFAAAGFWWFDGYLLVQERYWQG-IANDRPF
MSMEG_0999|M.smegmatis_MC2_155 --------PAVIAVLAVVAVFLVAGFWWFDGYTLVQERYWQG-IANNRPF
Mb0555c|M.bovis_AF2122/97 --------PAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQG-IAKDRPF
Rv0541c|M.tuberculosis_H37Rv --------PAVLAALVVAVSFAVAGFSWFDGYTLVQQRYWQG-IAKDRPF
MAV_4603|M.avium_104 --------PAALAAIAVAVAFAVAGFYWFDGYTLVQQRYWQG-IAKDRPF
MMAR_0887|M.marinum_M --------PAVLAALGVALAFAVAGFWWFDGYTLVQQRYWQG-IAHDRPF
MUL_0640|M.ulcerans_Agy99 --------PAVLAALGVALAFAVAGFWWFDGYTLVQQRYWQG-IAHDRPF
Mflv_0468|M.gilvum_PYR-GCK --------LCRDDTRRLTATLAVLAVAAAPNYLAQRGPYAKYGSDYSQVA
MAB_0962|M.abscessus_ATCC_1997 ADIGVAMGAGSSASRAVAQIVLLDNKFATLPYVVAEGRRVIG--NIERVS
:. . * . .:
Mvan_0891|M.vanbaalenii_PYR-1 QYWGWANFASVVCAIGLGSVAGLGRVFDIAAIKRRSGLHLLVLGALLAIV
MSMEG_0999|M.smegmatis_MC2_155 QYWSWANLASVVCAIGLGSVAGIGRVFDIKAARRNPGLPMLVIGALLAIT
Mb0555c|M.bovis_AF2122/97 GYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIA
Rv0541c|M.tuberculosis_H37Rv GYWSWANLACVVCAIGLGSVAGLSRVFDRAAISRRSGCHLLLLAVLAAIA
MAV_4603|M.avium_104 QYWSWANLACVVCAIGLGGVAGVGRVFDRAAIRRRSGFPLLLLAVLAAAA
MMAR_0887|M.marinum_M QYWSWANLACVVCAIGLGSVAGISRVVDAAAIRRRSGLHLLLLGMVAAIL
MUL_0640|M.ulcerans_Agy99 QYWSWANLACVVCAIGLGSVAGISRVVDAAAIRRRSGLHLPLLGMVAAIL
Mflv_0468|M.gilvum_PYR-GCK ELLARESGPRDCVVVDDRTAPSVPHAIEGARRAHPVAARDLGLAPPERTA
MAB_0962|M.abscessus_ATCC_1997 NLFLTKTVYSVLLALTVGLAGLGSKIFHYGAVPFPFQPIHVTIAAWFTIG
. .: . : .. :.
Mvan_0891|M.vanbaalenii_PYR-1 VADLSRLSKAETERIWLPFT------------------------------
MSMEG_0999|M.smegmatis_MC2_155 FADLSMLSKAETERIWLPFT------------------------------
Mb0555c|M.bovis_AF2122/97 LADLSMLSKAETERIWLPFT------------------------------
Rv0541c|M.tuberculosis_H37Rv LADLSMLSKAETERIWLPFT------------------------------
MAV_4603|M.avium_104 CADLSMLSKAEVERIWLPFT------------------------------
MMAR_0887|M.marinum_M VADLSMLSKAETERIWLPFT------------------------------
MUL_0640|M.ulcerans_Agy99 VADLSMLSKAETERIWLPFT------------------------------
Mflv_0468|M.gilvum_PYR-GCK LFSARDPLGVRADDLRTCAV------------------------------
MAB_0962|M.abscessus_ATCC_1997 IPAFILSLAPNNERAQTGFVRRVMLSAIPSGLTVGIATFLSYLLARQILH
. : .
Mvan_0891|M.vanbaalenii_PYR-1 --------------------VWLVASTALLPPRSARWWLALNVIGALAIN
MSMEG_0999|M.smegmatis_MC2_155 --------------------VWLTAAGALLPPRSHRWWLGLNVAGALALN
Mb0555c|M.bovis_AF2122/97 --------------------IWLTAAPALLPPRSHRLWLAVNAAGALLLN
Rv0541c|M.tuberculosis_H37Rv --------------------IWLTAAPALLPPRSHRLWLAVNAAGALLLN
MAV_4603|M.avium_104 --------------------IWLTAAAALLPVRTHRIWLALNAVGALAVN
MMAR_0887|M.marinum_M --------------------VWLTTAPALLRPRSDRLWLAVNAAGALAVN
MUL_0640|M.ulcerans_Agy99 --------------------VWLTTAPALLRPRSDRLWLAVNAAGALAVN
Mflv_0468|M.gilvum_PYR-GCK --------------------LWTIGDAAPGSPADAPVDRVARAQGFVPAE
MAB_0962|M.abscessus_ATCC_1997 VSGNSTQASTAALITELVAAVWVLAVVARPYQWWRVALVALSGLGYVAIF
:* * * :
Mvan_0891|M.vanbaalenii_PYR-1 HLILTNW-------------------------------------------
MSMEG_0999|M.smegmatis_MC2_155 HLILTNW-------------------------------------------
Mb0555c|M.bovis_AF2122/97 SIIFTNW-------------------------------------------
Rv0541c|M.tuberculosis_H37Rv SIIFTNW-------------------------------------------
MAV_4603|M.avium_104 TIILTHW-------------------------------------------
MMAR_0887|M.marinum_M SIIFTNW-------------------------------------------
MUL_0640|M.ulcerans_Agy99 SIIFTNW-------------------------------------------
Mflv_0468|M.gilvum_PYR-GCK RWRFNQTEVVRSVPAGARS-------------------------------
MAB_0962|M.abscessus_ATCC_1997 AIPLARKAFMLDPGNLAVTGPALGIGIAAAAVIEAVWWLQGKWSGQPRHF
: .
Mvan_0891|M.vanbaalenii_PYR-1 ------
MSMEG_0999|M.smegmatis_MC2_155 ------
Mb0555c|M.bovis_AF2122/97 ------
Rv0541c|M.tuberculosis_H37Rv ------
MAV_4603|M.avium_104 ------
MMAR_0887|M.marinum_M ------
MUL_0640|M.ulcerans_Agy99 ------
Mflv_0468|M.gilvum_PYR-GCK ------
MAB_0962|M.abscessus_ATCC_1997 WATGDD