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SYLIAVPDLMAHATTELSSIGSALTAANAAAAVPTTGVLAAGADDVSAAVASLFAGHAQAYQSLGGQVAA FHQQFLEGLRGASGAYVAAEAANVWPLQDLLGLINAPTQALLGRPLIGNGTNGTAANPNGGVGGLLIGNG GNGWNSTTGGAAGGNGGDAGLLGNGGTGGSGGAAGLVGNGGSGGSGGDGGTGGTADFLGGTQSTGGDGGG GGGGDAGVGGAGGALLGNGGAGGAGGNGGDGGGYVTSGNAPRGGGNGGEAGDGGLGGSAGMWGAGGAGGA AGTGGAGISGYPNGFGGSRGHRRQRRRWWHRWLVIRRRRCGRGRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0190 | - | - | 100% (326) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_2853 | - | 1e-91 | 55.09% (334) | PE-PGRS family protein |
| M. ulcerans Agy99 | MUL_4399 | - | 2e-91 | 53.74% (348) | PE-PGRS family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1097c | PE_PGRS20 | 4e-87 | 51.85% (351) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_5091 | - | 9e-45 | 53.76% (186) | triple helix repeat-containing collagen |
| M. tuberculosis H37Rv | Rv1068c | PE_PGRS20 | 1e-89 | 56.96% (316) | PE-PGRS family protein |
| M. leprae Br4923 | MLBr_01183 | - | 5e-13 | 39.13% (92) | hypothetical protein MLBr_01183 |
| M. abscessus ATCC 19977 | MAB_0321c | - | 2e-23 | 39.90% (203) | hypothetical protein MAB_0321c |
| M. marinum M | MMAR_4377 | - | 1e-141 | 68.15% (405) | PE-PGRS family protein |
| M. avium 104 | MAV_4827 | - | 4e-20 | 40.12% (172) | hypothetical protein MAV_4827 |
| M. smegmatis MC2 155 | MSMEG_0868 | - | 3e-47 | 45.31% (245) | hypothetical protein MSMEG_0868 |
| M. thermoresistible (build 8) | TH_3810 | - | 1e-27 | 35.42% (240) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_1264 | - | 2e-45 | 52.55% (196) | triple helix repeat-containing collagen |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 MHERLRERAGGVRKTLSDFAEGAGLKPSDTDDTRSPLRKPKFPAALAPES
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PLPDLKPRWERPTTAPDSETPSITQPQGRDTAADPAEQQATSTNTTDQPT
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0190|M.ulcerans_Agy99 --------------------------MSYLIAVPDLMAHATTELSSIGSA
MMAR_4377|M.marinum_M --------------------------MSYLIAAPDLMAHATTELSSIGSA
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 SDSLGAQPTAQVARQVQAPATDPAPAAPSLRPISGLLSVVTLGTTLIPNA
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------MSYMIAVPDMLSSAAGDLASIGSS
Rv1068c|M.tuberculosis_H37Rv --------------------------MSYMIAVPDMLSSAAGDLASIGSS
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------MNIVLGVSMAPSSIQMVVLEGEYA
MUL_0190|M.ulcerans_Agy99 LTAANAAAAVPTTGVLAAGADDVSAAVASLFAGHAQAYQSLGGQVAAFHQ
MMAR_4377|M.marinum_M LTAANAAAAVPTTGVLAAGADDVSAAVASLFAGHAQAYQSLGGQVAAFHQ
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 ---------------------MMFLAPPGGPGPISAAIQLTSTGSEATEP
TH_3810|M.thermoresistible__bu --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 PTEPADMPGVWAVMAWARRQPMYSDPAMRTTVNPQAQLPVPTVASAVLDP
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 INASTRAAAAATTRLLPAAADEVSAHIAALFSGHGEGYQAIARQMAAFHD
Rv1068c|M.tuberculosis_H37Rv INASTRAAAAATTRLLPAAADEVSAHIAALFSGHGEGYQAIARQMAAFHD
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 DGATVEEDAIDVTGADDAATASAPDRVISAILGTREGAADAGLQLSSIGV
MUL_0190|M.ulcerans_Agy99 QFLEGLRGASGAYVAAEAANVWPLQDLLGLINAPTQALLGRPLIGNGTNG
MMAR_4377|M.marinum_M QFLEGLRGASGAYAAAEAANVSPLQDLLGLINAPTQALLGRPLIGNGTNG
Mflv_5091|M.gilvum_PYR-GCK --MVTFGGGATPTPTSLGA--AAVDLSGTSCG----------LICNGQDG
Mvan_1264|M.vanbaalenii_PYR-1 WYVVSFGGSGAPTPNNLAA--SLVDLSGTSCG----------LICNGQDG
TH_3810|M.thermoresistible__bu --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 TQIVNWLIYQPLHAAGQQF--WVVSPIGSTLGGVINTISGQYLIGNGING
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 QFTLALTSSAGAYASAEAT--NVEQQVLGLINAPTQALWGRPLIGNGADG
Rv1068c|M.tuberculosis_H37Rv QFTLALTSSAGAYASAEAT--NVEQQVLGLINAPTQALLGRPLIGNGADG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 TWTDQLEAAALRDALAARRIDNVMLVSAFLAAAALAQNVGGAMGYERTAV
MUL_0190|M.ulcerans_Agy99 TAANPNGGVGGLLIGNGGNGWNSTTGGAAGGNGGDAGLLG----------
MMAR_4377|M.marinum_M TAANPNGGAGGLLIGNGGNGWNSTTGGAAGGNGGDAGLLG----------
Mflv_5091|M.gilvum_PYR-GCK TGQN-----GGILFGNGGSGWNSDVVGMDGGNGGNGGLFGGNGGNGGNGL
Mvan_1264|M.vanbaalenii_PYR-1 TGQN-----GGILFGNGGSGWNSEIAGVSGGNGGNAGLFGGNGGNGGNGL
TH_3810|M.thermoresistible__bu --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 TADNPNGGTGGLLFGDGGHGYDGSAAGLAGGNGGNAGLFG-NGGNGGVGW
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 TAANPNGGAGGLLYGNGGNGFSQTTAGLTGGTGGSAGLIG-NGGNGGAGG
Rv1068c|M.tuberculosis_H37Rv TAANPNGGAGGLLYGNGGNGFSQTTAGLTGGTGGSAGLIG-NGGNGGAGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 LLVEPDTATLAVVETSDGSIPDVYKQQIRAESYGDAAGQLSAMVAGLEKL
MUL_0190|M.ulcerans_Agy99 ---NGGTGGSG---------------------------------------
MMAR_4377|M.marinum_M ---NGGTGGSGGALAPGGTGGV----------------------------
Mflv_5091|M.gilvum_PYR-GCK GGGNGGNGGNAGAFALFGNGGNGGNGGVGVVGATGAVGAPGVAGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 GSGDGGNGGDAGLFSLFGRGGNGGNGGVGIAGATGAVGAPGVAGATGATG
TH_3810|M.thermoresistible__bu VDGDGGSGGRTGLFSKLSRGGDGGDG------------------------
MSMEG_0868|M.smegmatis_MC2_155 AGLDGGNGGSGGLLMGIGGAGGAGGVGADGTSAHVDGGTGGTGGTGGGTG
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 AGANGGAGGNGG--WLYGSGGNGGAGGAGPAGAIGAPGVAGGAGGAGGSA
Rv1068c|M.tuberculosis_H37Rv AGANGGAGGNGG--WLYGSGGNGGAGGAGPAGAIGAPGVAGGAGGAGGTA
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ESLPGGLLLVGSGVDVAPLKQVLQTTTFLDVSVAEEPETALARGAALAAA
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VTSGVVGGNGEDAVGYGATGAAGAAGAAGAAGAAG--------------A
Mvan_1264|M.vanbaalenii_PYR-1 VTSNVTGGNGADAVGYGATGAAGAAGAAGAAGKAG--------------A
TH_3810|M.thermoresistible__bu --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GTGGIGGTGGGLFGLLGHSGSTGAAGAAGNGGDGGNGGFGYVLIAGPNVT
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 GLFGNGGAGGAGGAGGQGGAGIGGADGTKGGDAGAGGAGGAGGWIHGHGG
Rv1068c|M.tuberculosis_H37Rv GLFGNGGAGGAG--------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 NAPLFASSTAALAYAQ----------------------------------
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK VGSAGAAGEAGETGTWGNAGLPGKAGDAGGAGAVGAAGAAGTVG-TAGAT
Mvan_1264|M.vanbaalenii_PYR-1 VGSAGTAGSAGAPGVWGNAGLPGAAGAAGGAGAIGTAGVAGAAG-TAGAT
TH_3810|M.thermoresistible__bu --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 VGSETRGGTGGAGGTGGQSTAAGPGKGGGGGGGGGGAILIGANGGTVDGH
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 VGGDGGTGGQGGDGVQGEPGDTGAAGGAGGAGGRGG-----------DGG
Rv1068c|M.tuberculosis_H37Rv --------------------------GAGGAGGRGG-----------DGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ---------------------------DPGTGAVDQYSLPDYLYVPVDPE
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M -GGWLYGNGGAGGAGGVGA-------------------------------
Mflv_5091|M.gilvum_PYR-GCK GGTGTGANGGAGGVGGVGGTGAAGAAG--GAGGLGETGTTGGAGGVGGQG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGVGGNGGAGQAGGIGGTGAAGAAG--QAGTAGETGVTGGVGGIGGQG
TH_3810|M.thermoresistible__bu ---GLGGNGGHG--------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 AIGGNGGNGGNGSTTAAGGNGGTGGTGRVIAEGTGSTAEGTATGGDGGHS
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 SAGWLSGNGGDAGTGGGGGNAGAGGEGGIFGGNGGNGGTGGTAGGGGNGG
Rv1068c|M.tuberculosis_H37Rv SAGWLSGNGGDAGTGGGGG-------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 PGDDELAYSAVGEEDAESPTVVIEKLFLPEDSEPRRRPVLLVGSGLAVVG
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK TAGGTGGVGGIGGAGSTGAVGGVGGKGIQG--GQGLQGGKGGDG------
Mvan_1264|M.vanbaalenii_PYR-1 TEGGTGGVGGVGGVGATGGAGGVGGKGIQG--GQGLQGGQGGDG------
TH_3810|M.thermoresistible__bu -----------------------GGTGIIS--LLSLAG-NGGNG------
MSMEG_0868|M.smegmatis_MC2_155 TGTGIGGNGGIGSVYAYGNNGAVSGTATGGRGGDGIDGGTGGAGGMGEIY
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 RGAALFGHGGNAGHGGAGGNGAAGGNGADTQLGISGKGGTGGGGG-----
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 ISAVLALEIALAIGIRTTGTVALQPTPNQHLIVPTEQAPAP---------
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------------GAGGKGGDADSMGSAG---------------------
Mvan_1264|M.vanbaalenii_PYR-1 -------------GTGGTGGDATSMGEAG---------------------
TH_3810|M.thermoresistible__bu -------------GNGYRTTDNNAL-------------------------
MSMEG_0868|M.smegmatis_MC2_155 SGADGEATGISAGGDGGSATGADSLGGRGGTSWVQAGYGPTTGGKASGTA
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 -----------GAGAGGTGGDGGLLYGNG---------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------ATGGKGGNGG---------------------NGGRGGLFGKG
Mvan_1264|M.vanbaalenii_PYR-1 --------ATGGKGGNGG---------------------NGGRGSLFGRG
TH_3810|M.thermoresistible__bu ---------DGGHGGNGG---------------------NVGFFSLFN--
MSMEG_0868|M.smegmatis_MC2_155 KAGHGGKASDGGKGGNGGDALVMAAGATGVATGNTAIGGNGGAASANGAV
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------GAGGNGGNGGAAGKGGIGAPGLSTAQGGDGGNGGSGGNAGNG
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M --------------------------------NGGGGGNAFLLGAGGAGG
Mflv_5091|M.gilvum_PYR-GCK GNAG-------------------NGADGGTGGAGGAGGTGGTGGAGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GNAG-------------------NGGNGGTGGNGGNGGTGGTGGNGGTGG
TH_3810|M.thermoresistible__bu -----------------------------LGGAGGWGGSG----------
MSMEG_0868|M.smegmatis_MC2_155 GGNGGFTNIAAIHGSITDSSATSGHGGAAQGGNGGNGGNGWVQAYDPNGP
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 GNGG------------------RGSVLFGHGGNAGHGGAGGNGAVSGNGG
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 -----------------------------PPVQASAPQPKISVPEPVAAP
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M VGGTGGVGALGGDGGTGGRGGWLCGDGGSGGSGGHGGVGAGGGEFPDPGG
Mflv_5091|M.gilvum_PYR-GCK TGGTGGIGGAGSTGGTGGTGGTGGTGG-TGGTGGTGGTGGTGGTGGKGGT
Mvan_1264|M.vanbaalenii_PYR-1 TGGTGGIGGAGSTGGTGGTGGTGGTGG-TGGTGGTGGTGGTGGTGGKGGT
TH_3810|M.thermoresistible__bu ------VDGVDVVGGNP-DGGTPGAHG-ESHTPGVYTD--RQGEDGEDGT
MSMEG_0868|M.smegmatis_MC2_155 AG--TTIDKGKAAGGNGGDGGFNGTGGATGGRGGDGAGASVWKANGQHST
MAB_0321c|M.abscessus_ATCC_199 -------MANIISNGPDGDAGATGAQGSQGATGAAGAMANCNWIDDDCAT
Mb1097c|M.bovis_AF2122/97 SS--ITAVGGKGGTGGGGGGGAGGTGGDAGLLYGNGGAGGTGGSGGAGAR
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 KPLSPPVAAPLPAAPPPAAPPLPEAPPIPAAPPVVPVPVVVPPVPVPVPV
MUL_0190|M.ulcerans_Agy99 -------------GAAGLVGNGGSGGSGGDGGTGGTADFLGGTQSTGG--
MMAR_4377|M.marinum_M G-----GGRGGSGGAAGLVGNGGSGGSGGGGGTGGTADFLGGTQSTGG--
Mflv_5091|M.gilvum_PYR-GCK GGTGGAGGTGGDGGTGGTGGTGGTGGTGGTGGTGGAGDGTGGTGGTGGTG
Mvan_1264|M.vanbaalenii_PYR-1 GGTGGDGGTGGTGGTGGTGGTGGTGGTGGTGGTGGAGDGLGGTGGTGGTG
TH_3810|M.thermoresistible__bu G-----TGIGGRGGNGGS--SSGTHPMAEDGEHVKALDGRPGLD------
MSMEG_0868|M.smegmatis_MC2_155 G-QTDTGGNGGRGGDGGTFVNAGANGNGGAGGAGGVSEGEGGTGGHGGDG
MAB_0321c|M.abscessus_ATCC_199 R-----GGTGGTGGNGGP------GGAGGPGGHGGVIDFEVETFMDG---
Mb1097c|M.bovis_AF2122/97 GGDGGAGSGTAQGGDGGAGGVGGNAGNGGNGGSAGWLSGNGGTGGGG---
Rv1068c|M.tuberculosis_H37Rv -----------------------NAGNGGNGGSAGWLSGNGGTGGGG---
MLBr_01183|M.leprae_Br4923 ---------------------MPLFLNAEPQALTAAANTLEGLSAAT---
MAV_4827|M.avium_104 RIPVPDPVSPPQLLAPPRLSVPQPVQPPVRVPQPPSPPQVGGTVPQSP--
MUL_0190|M.ulcerans_Agy99 --DGGGGGGGDAGVG------GAGGALLGNGGAG---------GAGGNGG
MMAR_4377|M.marinum_M --DGGAGG--DAGVG------GAGGALLGNGGAG---------GAGGNGG
Mflv_5091|M.gilvum_PYR-GCK GQGGQGGQGGTGGTG-------GQGGLGGGGGTG---------GQGGTGG
Mvan_1264|M.vanbaalenii_PYR-1 GFGGQGGQGGTGGTG-------GQGGLGGVGGTG---------GTGGTGG
TH_3810|M.thermoresistible__bu --GGNGSHGGNGGHG-------GRGGFLGIGGSG---------GWGGHGG
MSMEG_0868|M.smegmatis_MC2_155 GRGGDGALGGNGGTGGVGLGNGGKGGNGGNGGNGGTYVDPSHTGAGGNGG
MAB_0321c|M.abscessus_ATCC_199 -----VTLQAKGGRG-------GNGGHGGAGGTG---------GTGGKGG
Mb1097c|M.bovis_AF2122/97 ---GTAGAGGQGGNG-------NSGIDPGNGGQG------ADTGNAGNGG
Rv1068c|M.tuberculosis_H37Rv ---GTAGAGGQGGNG-------NSGIDPGNGGQG------ADTGNAGNGG
MLBr_01183|M.leprae_Br4923 ----VASNAAAAQLT-------TEIAPPAADDVS-------ILLAHFFSG
MAV_4827|M.avium_104 --PQHQTPPGEGTPP-------KPDGPGNYGGGHVP-----TPGAGGSGG
. .. .*
MUL_0190|M.ulcerans_Agy99 DGGGY------------VTSGNAPRGG-----------------------
MMAR_4377|M.marinum_M DGGGY------------VTSGNAPRGG-----------------------
Mflv_5091|M.gilvum_PYR-GCK TGGQG------------GTGGTGGTGGTG---------------------
Mvan_1264|M.vanbaalenii_PYR-1 TGGQG------------GTGGTGGTGGTG---------------------
TH_3810|M.thermoresistible__bu NGGD--------------TDADGGNGGDG---------------------
MSMEG_0868|M.smegmatis_MC2_155 NGGAGRIRVNNGTATGTATGGNGGNGGNGDADGHRGGKGGDGGEALIRAT
MAB_0321c|M.abscessus_ATCC_199 DGDDC------------EFGRTGGNGGTG---------------------
Mb1097c|M.bovis_AF2122/97 HGGSA-----------AKLFGDGGAGGAG---------------------
Rv1068c|M.tuberculosis_H37Rv HGGSA-----------AKLFGDGGAGGAG---------------------
MLBr_01183|M.leprae_Br4923 HGRQY--------------QAHASQGATN---------------------
MAV_4827|M.avium_104 SGGGH-----------VPTPGAGGSGGSG---------------------
* . *.
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1264|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 VIGSNASGTATGGDGGNGGTLGATNGTGGAATIVAYNVVQANPQASGTAT
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0190|M.ulcerans_Agy99 -GNGGEAGDGGLGGSAG-----------------MWGAGGAGGAAGTGGA
MMAR_4377|M.marinum_M -GNGGEAGDGGLGGSAG-----------------MWGAGGAGGAAGTGGA
Mflv_5091|M.gilvum_PYR-GCK -GTGGAGGDGGLGGLGG-----------------FGGSGGTGGQGGLGGP
Mvan_1264|M.vanbaalenii_PYR-1 -GTGGAGGDGGLGGLGG-----------------FGGVGGTGGQGGQGGP
TH_3810|M.thermoresistible__bu -GNGGSAGRGGTGGLRG-----------------VFGINGGNGRAGLGGR
MSMEG_0868|M.smegmatis_MC2_155 DGHGGSGINGGHGGNGGQGTIEANGPSAVASGIGAGGNGGDGIDGGLGGN
MAB_0321c|M.abscessus_ATCC_199 -GRGGDGNFAGTGGNGG------------------AILVKCQHDLSLG--
Mb1097c|M.bovis_AF2122/97 -GMGSTGGTGGGGGFGG----------------GTGGNGGNGHAGGAGGS
Rv1068c|M.tuberculosis_H37Rv -GMGSTGGTGGGGGFGG----------------GTGGNGGNGHAGGAGGS
MLBr_01183|M.leprae_Br4923 HQDLIQSLLTSSSAYAG---------------------TETANHDSL---
MAV_4827|M.avium_104 GGHVPTPGTGGPGGTGG-------------------SGGGHVPTPGAGTP
. .. * .
MUL_0190|M.ulcerans_Agy99 GIS---------------------GYPNGFGGSRGHRRQRR---------
MMAR_4377|M.marinum_M GIS---------------------GYPNGFGGSGGTGGNGG---------
Mflv_5091|M.gilvum_PYR-GCK GG--------------------STGGAGGAGGQAGTAGKGG---------
Mvan_1264|M.vanbaalenii_PYR-1 GG--------------------STGGAGGAGGQAGVAGKGG---------
TH_3810|M.thermoresistible__bu GX--------------------XXX--GGGVGAAVRSGNGV---------
MSMEG_0868|M.smegmatis_MC2_155 GGDGVVNTTANAANPGSATGTATGGDGGKATGTASQGGNGGPSWVQSGYG
MAB_0321c|M.abscessus_ATCC_199 --------------------------THPMDVSAGTGGNGG---------
Mb1097c|M.bovis_AF2122/97 GG------------------TAGLLGSGG---TGGDGGNGG---------
Rv1068c|M.tuberculosis_H37Rv GG------------------TAGLLGSGGSGGTGGDGGNGG---------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GG--------------------------SGGGHLPFPGAGS---------
MUL_0190|M.ulcerans_Agy99 -RWWHR----WLVIRRRRCGRGRR--------------------------
MMAR_4377|M.marinum_M -NGGGGGTGGWLYGDGGAGGAGGSGGPGGTTHDQYIGGDGGDGGDGGAGG
Mflv_5091|M.gilvum_PYR-GCK -LFGGSGSAGKAGATGAAGASGGKGAQGATGAQGATG----AQGATGATG
Mvan_1264|M.vanbaalenii_PYR-1 -LFGGSGSAGTAGVTGASGASGGKGAQGATGAQGATG----AQGATGATG
TH_3810|M.thermoresistible__bu -FSGGGGTP-----------SAGFGVP--TTIQFPAG----SCTSRAVSR
MSMEG_0868|M.smegmatis_MC2_155 STLGGNATGTATAGKGGEASNGGVAGNGGNALVMAAGTTGVATGNTATGG
MAB_0321c|M.abscessus_ATCC_199 --IGGGGGG-----------GGSVGANGATTGVFSSS--------SDCSG
Mb1097c|M.bovis_AF2122/97 --LGAGSGAK------GNGGNGGDGGKGGDAQLIGNGG---NGGNGGKGG
Rv1068c|M.tuberculosis_H37Rv --LGAGSGAK------GNGGNGGDGGKGGDAQLIGNGG---NGGNGGKGG
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --TPGGSGGGHLPTPGAGTPGGGLGGFGGGHAPAPGG--------GLGGG
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M DAQHIGNGGAGGERG-----AAGTGGSGFADGSAGSGGAGGTGGSLWGAN
Mflv_5091|M.gilvum_PYR-GCK AAGKAGATGAAGAAG-----AAGSAGTTGAQGSAGTNGAN-GANGSQGAA
Mvan_1264|M.vanbaalenii_PYR-1 ASGAQGSAGSAGSAG-----VAGSAGTTGAQGSAGTNGAN-GANGSQGAA
TH_3810|M.thermoresistible__bu EGIMPSSRAASARAG-----AACASSTSRSRRSFCCSRA-----------
MSMEG_0868|M.smegmatis_MC2_155 DGGAATTAGATGGAGGFSNIAAIHGAITDSTAISGHGGAGNGGNGGKGAD
MAB_0321c|M.abscessus_ATCC_199 PGPQPNP-GSPGDPG-------TSVAVSGAQGNPGQAQFLIVP-------
Mb1097c|M.bovis_AF2122/97 TGLMPGINGTGGAGG-------SRGQISGNPGTPGQ--------------
Rv1068c|M.tuberculosis_H37Rv TGLMPGINGTGGAGG-------SRGQISGNPGTPGQ--------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 GGHAPAPGGGLGGFG--------GGHSGGGLGGLGGGHK-----------
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M GASGL---------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK GKAGATGTTGATG--------AAGEDGDAGSGGSG-INGGAGGAGG----
Mvan_1264|M.vanbaalenii_PYR-1 GKAGATGTTGATG--------AAGDAGDPGSEAVD-INGGAGGAGG----
TH_3810|M.thermoresistible__bu --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 GWVQAYDPAGPVGSKIANSSAVAGNGGDGGVNGTGGASGGDGGNGGNTSV
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0190|M.ulcerans_Agy99 --------------------------------------------------
MMAR_4377|M.marinum_M --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK -------AGGEGGEGGDGGKGGAGAEGGAGGGGGAGGSGAGGAG------
Mvan_1264|M.vanbaalenii_PYR-1 -------AGGEGGEGGAGGAGGDGSEGGAGGSGGAGGSGTGGAG------
TH_3810|M.thermoresistible__bu --------------------------------------------------
MSMEG_0868|M.smegmatis_MC2_155 WKSGGQTADGEHNTGGNGGNGGDGSEPGPGGNGAGGAGGNGGTGGTTAGG
MAB_0321c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1097c|M.bovis_AF2122/97 --------------------------------------------------
Rv1068c|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01183|M.leprae_Br4923 --------------------------------------------------
MAV_4827|M.avium_104 --------------------------------------------------
MUL_0190|M.ulcerans_Agy99 ------------------------------
MMAR_4377|M.marinum_M ------------------------------
Mflv_5091|M.gilvum_PYR-GCK -GAGGSGGSGGSGGSGGSGGAAGDSDD---
Mvan_1264|M.vanbaalenii_PYR-1 -GAGGSGGSGGSGGAGGSGGAAGDSD----
TH_3810|M.thermoresistible__bu ------------------------------
MSMEG_0868|M.smegmatis_MC2_155 SGNGGNGGNGGNGGADGTPGTAGTTGANNP
MAB_0321c|M.abscessus_ATCC_199 ------------------------------
Mb1097c|M.bovis_AF2122/97 ------------------------------
Rv1068c|M.tuberculosis_H37Rv ------------------------------
MLBr_01183|M.leprae_Br4923 ------------------------------
MAV_4827|M.avium_104 ------------------------------