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LNLPSYPSKAVTSAAAKVAVVKSSLGRRRTGGGDGGRAVFAEVGYERATIRGIAAAAGVDKTSIIKYFGT KQALFHEAVHWDIPVAELSTDDAGQTTENYARAMLTAWAADPNSPMAVLLRTSMTSEDAADILRRHITTQ GVDAVAATIDATDARLRAAVAGAILKGIASQPFILRMPGLVNADIDDILRLVTPLLRSLIDPE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0080 | - | - | 100% (204) | transcriptional regulator |
| M. ulcerans Agy99 | MUL_4899 | - | 1e-18 | 31.76% (170) | hypothetical protein MUL_4899 |
| M. ulcerans Agy99 | MUL_3981 | - | 1e-12 | 27.65% (170) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 3e-11 | 25.14% (179) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_0253 | - | 2e-16 | 32.92% (161) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 3e-11 | 25.14% (179) | hypothetical protein Rv1685c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4776c | - | 2e-49 | 58.08% (167) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0088 | - | 1e-85 | 94.12% (170) | transcriptional regulator |
| M. avium 104 | MAV_3088 | - | 1e-09 | 27.06% (170) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1700 | - | 3e-18 | 33.33% (162) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3542 | - | 3e-15 | 29.81% (161) | PUTATIVE transcriptional regulator, TetR family |
| M. vanbaalenii PYR-1 | Mvan_0641 | - | 2e-15 | 31.90% (163) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1711c|M.bovis_AF2122/97 ---------MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTS
Rv1685c|M.tuberculosis_H37Rv ---------MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTS
MAV_3088|M.avium_104 ---------MTTTGTTRRRRGRPAGSSGSRERILASARELFARNGIRNTS
TH_3542|M.thermoresistible__bu --------------------------------VLAAAKRRFAQDGYEKTT
Mvan_0641|M.vanbaalenii_PYR-1 ---------MPRPGETARRRGRRQGEPVSKEAVLAAAKTRFARDGYEKTT
Mflv_0253|M.gilvum_PYR-GCK ---------MPPPAQTGRRRGRRKGDPVSRETVLAAAKGRFARDGFEKTT
MSMEG_1700|M.smegmatis_MC2_155 ---------------------MRRSAAETKSVILAAARERFAADGYERAT
MUL_0080|M.ulcerans_Agy99 MLNLPSYPSKAVTSAAAKVAVVKSSLGRRRTGGGDGGRAVFAEVGYERAT
MMAR_0088|M.marinum_M MTIGEQVPEGPVESVPS--TERKGQRTRRRIL--DAARAVFAEVGYERAT
MAB_4776c|M.abscessus_ATCC_199 ------MPKR---------------------------RQVFAEVGYVKAT
: ** * .::
Mb1711c|M.bovis_AF2122/97 IRAVAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIR--EAPV
Rv1685c|M.tuberculosis_H37Rv IRAVAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIR--EAPV
MAV_3088|M.avium_104 IRAVAAAAGVDSALVHHYFGTKEKLFAAAVQIPIDPMQVIGPLR--EVPV
TH_3542|M.thermoresistible__bu LRAIARDAHVDASMVLYLFGSKAELFRESLELILDPEMLVAAMT---GDD
Mvan_0641|M.vanbaalenii_PYR-1 LRAIADDARVDASMVLYLFGSKEQLFREALRLILDPEVLVAALAGVEGDS
Mflv_0253|M.gilvum_PYR-GCK LRAIAEDAGVDASMVLYLFGSKEALFRESLRLILDPGVLIEALS---GGE
MSMEG_1700|M.smegmatis_MC2_155 IRSIAADASIDPSMVMRYFGNKERLFAAAAEFDLELPDLALVPR------
MUL_0080|M.ulcerans_Agy99 IRGIAAAAGVDKTSIIKYFGTKQALFHEAVHWDIPVAELSTDDA------
MMAR_0088|M.marinum_M IRGIAAAAGVDKSSIIKYFGTKQALFHEAVHWDIPVAELTTDDA------
MAB_4776c|M.abscessus_ATCC_199 IRGIAAVADVDKSSVTQYFGSTSNPFREAVQWRIPVDELTVPDL------
:*.:* * :* : : **.. * : . : :
Mb1711c|M.bovis_AF2122/97 EELGYKLPSLLLPIWDS-ELGAGLIATLRSLISG-SDVGLARSFLEEVVT
Rv1685c|M.tuberculosis_H37Rv EELGYKLPSLLLPIWDS-ELGAGLIATLRSLISG-SDVGLARSFLEEVVT
MAV_3088|M.avium_104 DDLGYALPSMLLPLWDS-EVGAAFIATLRSILAG-EEISLFRTFIQDVIG
TH_3542|M.thermoresistible__bu GDVGTRMVRVYLQIWESPDTGPTIRAMLQSATSNTDAREAFRSFLREYLL
Mvan_0641|M.vanbaalenii_PYR-1 SDVGTRMVRTYLGIWEAADSAASMRAMLASATSNPDAHEAFRSFMQDYVL
Mflv_0253|M.gilvum_PYR-GCK ADIGTRMVRAYLGVWESPESAESMRTMLASATSNPDAREAFRGFIQDYVL
MSMEG_1700|M.smegmatis_MC2_155 EEIGATLAGHFLERWER---DEALLILLRAGVTNEAVAERMRTIFAAQLA
MUL_0080|M.ulcerans_Agy99 GQTTENYARAMLTAWAA-DPNSPMAVLLRTSMTSEDAADILRRHITTQGV
MMAR_0088|M.marinum_M GQTTENYARAMLTAWAA-DPNSPMAVLLRTSMTSEDAADILRRHITAQGV
MAB_4776c|M.abscessus_ATCC_199 AVTAENYLRGLLSGWAA-EPAGPMAVLLRNSMTSDDALELLREQVTDHAV
* * : * :. * .
Mb1711c|M.bovis_AF2122/97 VELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQ
Rv1685c|M.tuberculosis_H37Rv VELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQ
MAV_3088|M.avium_104 VEVGPRVDNPAGSGVIRIQFVASQLVGVVMARYILELEPFASLPPEQIAA
TH_3542|M.thermoresistible__bu TAVSGVLGG-GEQARLRAELAATGLVGTAMLRYIMRVPPLAELSTEEVVR
Mvan_0641|M.vanbaalenii_PYR-1 TAVSGVLGG-GEQARLRAMLAASSLVGTAMLRYVMRVAPLAELPTEDVVR
Mflv_0253|M.gilvum_PYR-GCK AAVVGTLGG-DDRARLRAMLAASSLVGTAMMRYLMEIPPLSELATEDVIR
MSMEG_1700|M.smegmatis_MC2_155 PVIAKLTGG-APDAPVRASLAASQVLGMALCRYVLAFPPLVDMSRDGVVA
MUL_0080|M.ulcerans_Agy99 DAVAATIDA--TDARLRAAVAGAILKGIASQPFILRMPGLVNADIDDILR
MMAR_0088|M.marinum_M DAVAATIDA--SDARLRAAVAGAILMGIASQRFILRMPDLVDADIDDILR
MAB_4776c|M.abscessus_ATCC_199 SSVAATIDQ--PDARLRAALLSAVLMVVASQRYLLRLPDLAGASDDDIVA
: . . :* . .: : . ::: . : : :
Mb1711c|M.bovis_AF2122/97 TIAPNLQRYLTGELPDDLAP-------
Rv1685c|M.tuberculosis_H37Rv TIAPNLQRYLTGELPDDLAP-------
MAV_3088|M.avium_104 TIAPNLQRYLTGDLPDGLAP-------
TH_3542|M.thermoresistible__bu MLAPTVNRYLTADADELGLPSSLTAGS
Mvan_0641|M.vanbaalenii_PYR-1 LVAPTVTRYLTADARELGLPD------
Mflv_0253|M.gilvum_PYR-GCK LVAPTVTRYLTAPADELGLPG------
MSMEG_1700|M.smegmatis_MC2_155 WIGPTLQRYLVG---------------
MUL_0080|M.ulcerans_Agy99 LVTPLLRSLIDPE--------------
MMAR_0088|M.marinum_M LVTPLLRSLIDPE--------------
MAB_4776c|M.abscessus_ATCC_199 LVAPLLTALIAPENAS-----------
: * : :