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TIGEQVPEGPVESVPSTERKGQRTRRRILDAARAVFAEVGYERATIRGIAAAAGVDKSSIIKYFGTKQAL FHEAVHWDIPVAELTTDDAGQTTENYARAMLTAWAADPNSPMAVLLRTSMTSEDAADILRRHITAQGVDA VAATIDASDARLRAAVAGAILMGIASQRFILRMPDLVDADIDDILRLVTPLLRSLIDPE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0088 | - | - | 100% (200) | transcriptional regulator |
| M. marinum M | MMAR_3397 | - | 6e-23 | 32.78% (180) | putative regulatory protein |
| M. marinum M | MMAR_0204 | - | 8e-22 | 33.15% (181) | hypothetical protein MMAR_0204 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1711c | - | 2e-16 | 28.19% (188) | hypothetical protein Mb1711c |
| M. gilvum PYR-GCK | Mflv_0253 | - | 2e-20 | 32.97% (182) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1685c | - | 2e-16 | 28.19% (188) | hypothetical protein Rv1685c |
| M. leprae Br4923 | MLBr_02568 | - | 1e-05 | 23.31% (163) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4776c | - | 3e-52 | 61.08% (167) | TetR family transcriptional regulator |
| M. avium 104 | MAV_3088 | - | 1e-13 | 29.05% (179) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1700 | - | 2e-23 | 36.36% (176) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3542 | - | 4e-19 | 31.95% (169) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0080 | - | 7e-86 | 94.12% (170) | transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_0641 | - | 2e-19 | 31.91% (188) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0088|M.marinum_M MTIGEQVPEGPVESVPS--TERKGQRTRRRIL--DAARAVFAEVGYERAT
MUL_0080|M.ulcerans_Agy99 MLNLPSYPSKAVTSAAAKVAVVKSSLGRRRTGGGDGGRAVFAEVGYERAT
MAB_4776c|M.abscessus_ATCC_199 ------MPKR---------------------------RQVFAEVGYVKAT
Mb1711c|M.bovis_AF2122/97 ---------MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTS
Rv1685c|M.tuberculosis_H37Rv ---------MAAPDNSRRRPGRPAGSSDTRERILSSARELFAHNGIDRTS
MAV_3088|M.avium_104 ---------MTTTGTTRRRRGRPAGSSGSRERILASARELFARNGIRNTS
Mflv_0253|M.gilvum_PYR-GCK ---------MPPPAQTGRRRGRRKGDPVSRETVLAAAKGRFARDGFEKTT
Mvan_0641|M.vanbaalenii_PYR-1 ---------MPRPGETARRRGRRQGEPVSKEAVLAAAKTRFARDGYEKTT
TH_3542|M.thermoresistible__bu --------------------------------VLAAAKRRFAQDGYEKTT
MSMEG_1700|M.smegmatis_MC2_155 ---------------------MRRSAAETKSVILAAARERFAADGYERAT
MLBr_02568|M.leprae_Br4923 ----------------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYHKTS
*: * .::
MMAR_0088|M.marinum_M IRGIAAAAGVDKSSIIKYFGTKQALFHEAVHWDIPVAELTTDDAGQT---
MUL_0080|M.ulcerans_Agy99 IRGIAAAAGVDKTSIIKYFGTKQALFHEAVHWDIPVAELSTDDAGQT---
MAB_4776c|M.abscessus_ATCC_199 IRGIAAVADVDKSSVTQYFGSTSNPFREAVQWRIPVDELTVPDLAVT---
Mb1711c|M.bovis_AF2122/97 IRAVAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAP--V
Rv1685c|M.tuberculosis_H37Rv IRAVAAKAGVDAALVHHYFGTKQQLFAAAIHIPIDPMVIIGPIREAP--V
MAV_3088|M.avium_104 IRAVAAAAGVDSALVHHYFGTKEKLFAAAVQIPIDPMQVIGPLREVP--V
Mflv_0253|M.gilvum_PYR-GCK LRAIAEDAGVDASMVLYLFGSKEALFRESLRLILDPGVLIEALSGGE---
Mvan_0641|M.vanbaalenii_PYR-1 LRAIADDARVDASMVLYLFGSKEQLFREALRLILDPEVLVAALAGVEGDS
TH_3542|M.thermoresistible__bu LRAIARDAHVDASMVLYLFGSKAELFRESLELILDPEMLVAAMTGDD---
MSMEG_1700|M.smegmatis_MC2_155 IRSIAADASIDPSMVMRYFGNKERLFAAAAEFDLELPDLALVP------R
MLBr_02568|M.leprae_Br4923 MDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDFT--
: .:* * :. . : :*.. * . . :
MMAR_0088|M.marinum_M ---TENYARAMLTAWAA-DPNSPMAVLLRTSMTSEDAADILRRHITAQGV
MUL_0080|M.ulcerans_Agy99 ---TENYARAMLTAWAA-DPNSPMAVLLRTSMTSEDAADILRRHITTQGV
MAB_4776c|M.abscessus_ATCC_199 ---AENYLRGLLSGWAA-EPAGPMAVLLRNSMTSDDALELLREQVTDHAV
Mb1711c|M.bovis_AF2122/97 EELGYKLPSLLLPIWDS-ELGAGLIATLRSLISG-SDVGLARSFLEEVVT
Rv1685c|M.tuberculosis_H37Rv EELGYKLPSLLLPIWDS-ELGAGLIATLRSLISG-SDVGLARSFLEEVVT
MAV_3088|M.avium_104 DDLGYALPSMLLPLWDS-EVGAAFIATLRSILAG-EEISLFRTFIQDVIG
Mflv_0253|M.gilvum_PYR-GCK ADIGTRMVRAYLGVWESPESAESMRTMLASATSNPDAREAFRGFIQDYVL
Mvan_0641|M.vanbaalenii_PYR-1 SDVGTRMVRTYLGIWEAADSAASMRAMLASATSNPDAHEAFRSFMQDYVL
TH_3542|M.thermoresistible__bu GDVGTRMVRVYLQIWESPDTGPTIRAMLQSATSNTDAREAFRSFLREYLL
MSMEG_1700|M.smegmatis_MC2_155 EEIGATLAGHFLERWER---DEALLILLRAGVTNEAVAERMRTIFAAQLA
MLBr_02568|M.leprae_Br4923 QSPKDLLRNTIVSFLRYIDANRASWIVMYIQAMSLPAFAQTVREARDQIT
: : .
MMAR_0088|M.marinum_M DAVAATIDA--SDARLRAAVAGAILMGIASQRFILRMPDLVDADIDDILR
MUL_0080|M.ulcerans_Agy99 DAVAATIDA--TDARLRAAVAGAILKGIASQPFILRMPGLVNADIDDILR
MAB_4776c|M.abscessus_ATCC_199 SSVAATIDQ--PDARLRAALLSAVLMVVASQRYLLRLPDLAGASDDDIVA
Mb1711c|M.bovis_AF2122/97 VELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQ
Rv1685c|M.tuberculosis_H37Rv VELGSRVDNPPGTGKIRTQFVASQLMGVVMARYIVRIEPFASLPAEQIVQ
MAV_3088|M.avium_104 VEVGPRVDNPAGSGVIRIQFVASQLVGVVMARYILELEPFASLPPEQIAA
Mflv_0253|M.gilvum_PYR-GCK AAVVGTLGG-DDRARLRAMLAASSLVGTAMMRYLMEIPPLSELATEDVIR
Mvan_0641|M.vanbaalenii_PYR-1 TAVSGVLGG-GEQARLRAMLAASSLVGTAMLRYVMRVAPLAELPTEDVVR
TH_3542|M.thermoresistible__bu TAVSGVLGG-GEQARLRAELAATGLVGTAMLRYIMRVPPLAELSTEEVVR
MSMEG_1700|M.smegmatis_MC2_155 PVIAKLTGG-APDAPVRASLAASQVLGMALCRYVLAFPPLVDMSRDGVVA
MLBr_02568|M.leprae_Br4923 ELVAGLMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAVDEAAE
: . : :
MMAR_0088|M.marinum_M LVTPLLRSLIDPE--------------
MUL_0080|M.ulcerans_Agy99 LVTPLLRSLIDPE--------------
MAB_4776c|M.abscessus_ATCC_199 LVAPLLTALIAPENAS-----------
Mb1711c|M.bovis_AF2122/97 TIAPNLQRYLTGELPDDLAP-------
Rv1685c|M.tuberculosis_H37Rv TIAPNLQRYLTGELPDDLAP-------
MAV_3088|M.avium_104 TIAPNLQRYLTGDLPDGLAP-------
Mflv_0253|M.gilvum_PYR-GCK LVAPTVTRYLTAPADELGLPG------
Mvan_0641|M.vanbaalenii_PYR-1 LVAPTVTRYLTADARELGLPD------
TH_3542|M.thermoresistible__bu MLAPTVNRYLTADADELGLPSSLTAGS
MSMEG_1700|M.smegmatis_MC2_155 WIGPTLQRYLVG---------------
MLBr_02568|M.leprae_Br4923 LMINLFWHGLKGAPADRDFGPSIVAG-
: . :