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ATNDSGAEYSPRAAAVKVLDVLAALSERGGCHRIVDLAARTELPKATVYRLLQHLVSQGFVVAEPDSTYR IGPRFLGIAAAALSDAPWRKTVAAALESLRTATGLSAHFAQQYGGNLVIVDAVESLDPFGIPVRPGLTTA IEQTALGQAIVSTSSEAVVSQDPARQLRWVAAPVFHRRGEVLGALGVAGTDFTLADQALDRVRAVVRSAA ADASAVLTAPSFGHRGTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6864 | - | - | 100% (229) | putative transcription regulator |
| M. smegmatis MC2 155 | MSMEG_3784 | - | 7e-10 | 28.69% (122) | transcriptional regulator, IclR family protein |
| M. smegmatis MC2 155 | MSMEG_2386 | - | 3e-08 | 27.62% (181) | transcriptional regulator, IclR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3013 | - | 1e-08 | 29.00% (200) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_3087 | - | 2e-09 | 26.72% (262) | transcriptional regulator, TrmB |
| M. tuberculosis H37Rv | Rv2989 | - | 1e-08 | 29.00% (200) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4493 | - | 1e-08 | 28.78% (139) | IclR family transcriptional regulator |
| M. marinum M | MMAR_1725 | - | 2e-07 | 27.87% (183) | transcriptional regulatory protein |
| M. avium 104 | MAV_3839 | - | 5e-08 | 27.62% (181) | transcriptional regulator, IclR family protein |
| M. thermoresistible (build 8) | TH_3251 | - | 1e-07 | 25.85% (147) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_1967 | - | 1e-06 | 27.32% (183) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4411 | - | 1e-11 | 30.67% (150) | regulatory proteins, IclR |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3251|M.thermoresistible__bu MTATLDQPTPNTTVKRTGTERTGETPSAVLDRISLVLDAFDGP-GRLTLA
Mvan_4411|M.vanbaalenii_PYR-1 MNQASIAIDP---VRSSEHDSIHQSPTNSVRRTLQVLAAFDGSRTVLGVS
Mb3013|M.bovis_AF2122/97 --------------------MRQHSGIGVLDKAVGVLHAVAES--PCGLA
Rv2989|M.tuberculosis_H37Rv --------------------MRQHSGIGVLDKAVGVLHAVAES--PCGLA
MMAR_1725|M.marinum_M --------------------MRQDSGIGVIDKAVGLLRATAES--PCGLA
MUL_1967|M.ulcerans_Agy99 --------------------MRQDSGIGVIDKAVGLLRATAKS--PCGLA
MAV_3839|M.avium_104 ---------------------------------MGVLHTVAQS--PCGLA
Mflv_3087|M.gilvum_PYR-GCK --------MAQHDKTSTTSPTDAPAAVQSVDRALQVLEIVAAHG-QAGVT
MAB_4493|M.abscessus_ATCC_1997 --------------------------MSVLTRAAQILDALAESNSGLSVR
MSMEG_6864|M.smegmatis_MC2_155 --------------MATNDSGAEYSPRAAAVKVLDVLAALSERGGCHRIV
:* :
TH_3251|M.thermoresistible__bu QVVRRTGLPRSSAHRMLERLVQLRWLRRDGR--DYELGMRLVELGSLAVH
Mvan_4411|M.vanbaalenii_PYR-1 EVAARADVPKSTAHRLLNVMSQQGFVRREGN--RYRLGERLFELGARALE
Mb3013|M.bovis_AF2122/97 ELCDRTDLPRATAYRLAAALEVHRLLGRGQD-GHWRLGPAITELATHVDD
Rv2989|M.tuberculosis_H37Rv ELCDRTDLPRATAYRLAAALEVHRLLGRGQD-GHWRLGPAITELATHVDD
MMAR_1725|M.marinum_M ELCERTGLPRATAYRLAAALEVHRLLGRDED-GRWGLGPAITELAAHVDD
MUL_1967|M.ulcerans_Agy99 ELCERTGLPRATAYRLAAALEVHRLLGRDED-GRWGLGPAITELAAHVDD
MAV_3839|M.avium_104 ELCERTELPRATAYRLAAALEVHRLLARGDD-GRWRLGPAVTELAAHVND
Mflv_3087|M.gilvum_PYR-GCK EIAAELGVHKSTVSRLVAVLEARGYVEQVSERGKYRLGFAIPRLAHVAGG
MAB_4493|M.abscessus_ATCC_1997 ELAEATGLPKSSVHRIVQELTVSQYVMAGGRGGSYQLGPGLLKLGLNNRR
MSMEG_6864|M.smegmatis_MC2_155 DLAARTELPKATVYRLLQHLVSQGFVVAEPD-STYRIGPRFLGIAAAALS
:: : :::. *: : : : :* . :.
TH_3251|M.thermoresistible__bu QDRLHRAAIPRLHELHAATGLVVHLAVLDGSDVVYLEKVGSRLAAAIPTR
Mvan_4411|M.vanbaalenii_PYR-1 PRGLRERAIPFMAELHHSTLETIHLAVLRGDQVLYVEKIYGHGAAPCPTT
Mb3013|M.bovis_AF2122/97 P--LLVACAAVLPQLRDATGESVQVYRREGTSRVCVAALEPAAGLRDTVP
Rv2989|M.tuberculosis_H37Rv P--LLVACAAVLPQLRDATGESVQVYRREGTSRVCVAALEPAAGLRDTVP
MMAR_1725|M.marinum_M P--LLTAGATVLPRLRETTGESVQLYRREGTSRVCVAALEPPAGLRDTVP
MUL_1967|M.ulcerans_Agy99 P--LLTAGATVLPRLCETTGESVQLYRREGTSRVCVAALEPPAGLRDTVP
MAV_3839|M.avium_104 P--LLAAGSAVLPLLRETTGESVQLYRREGTDRVCVAALEPAAGLRDTVP
Mflv_3087|M.gilvum_PYR-GCK QNDLVKLGQAACDMLSAGVGETANLAVLDADRIVNIVEAIGPSEITLRTW
MAB_4493|M.abscessus_ATCC_1997 Q--FVAPMRKAIATVAREVNENIDLAMLSGGELVIIEQIATVRNLPTVTV
MSMEG_6864|M.smegmatis_MC2_155 DAPWRKTVAAALESLRTATGLSAHFAQQYGGNLVIVDAVESLDPFGIPVR
: . .. . : : .
TH_3251|M.thermoresistible__bu VGGRRPANCAAVGKAILAYAEDDGVLSGTGP-LPRNTKYSISDPARLRAE
Mvan_4411|M.vanbaalenii_PYR-1 VGGRNPATCTGLGKAILSSCSEEAVDAILGSRLPRPTRNSLHTRQALHRN
Mb3013|M.bovis_AF2122/97 VGARLPMTAGSGAKVLLAHTDAATQAAVL--PKAVFSAR----------A
Rv2989|M.tuberculosis_H37Rv VGARLPMTAGSGAKVLLAHTDAATQAAVL--PKAVFSAR----------A
MMAR_1725|M.marinum_M VGARLPMTAGSGAKVLLAHSDPATQQAVL--PTAKFTDR----------V
MUL_1967|M.ulcerans_Agy99 VGARLPMTAGSGAKVLLAHSDPATQQAVL--PTAKFTDR----------V
MAV_3839|M.avium_104 VGARLPMTAGSGAKVLLAHSDAATQKAVL--ANAKFTER----------T
Mflv_3087|M.gilvum_PYR-GCK VGQSCPAYATSSGKVLLAGLDPAELPARIRPPLTEFTDSTLCGLAELQDE
MAB_4493|M.abscessus_ATCC_1997 VGRTFALHASSIGKALLSQLPPDQVRNMLPADLEVFTTNTITDVTALLRE
MSMEG_6864|M.smegmatis_MC2_155 PGLTTAIEQTALGQAIVSTSSEAVVSQDPARQLRWVAAP-----------
* . . .:.::: :
TH_3251|M.thermoresistible__bu LAKVRAHGVAFDREESLPGIGCVAAPIGD--PGEAVAAISVCGPMNQMAF
Mvan_4411|M.vanbaalenii_PYR-1 LTISREEGVAVDYEELRMGLACVSAPIIDRSTGAAVAALSISAPTSRFNR
Mb3013|M.bovis_AF2122/97 LAEVCRRGWAQSVAEREPGVASVSAPVRD-GRGVVIAAISVSGPIDRMGR
Rv2989|M.tuberculosis_H37Rv LAEVCRRGWAQSVAEREPGVASVSAPVRD-GRGVVIAAISVSGPIDRMGR
MMAR_1725|M.marinum_M LAEVRRRGWAQSVAEREPGVASVSAPVRD-GRGVVVAAISVSGPIDRIGR
MUL_1967|M.ulcerans_Agy99 LAEVRRRGWAQSVAEREPGVASVSAPVRD-GRGVVVAAISVSGPIDRIGR
MAV_3839|M.avium_104 LAEVRRRGWAQSVAEREPGVASVSAPVRD-SRGAVIAAISVSGPIDRIGR
Mflv_3087|M.gilvum_PYR-GCK LAAVRERGWACVREELEVGLNAVAAPVYD-VHAQVIAALSVSGPSYRLAV
MAB_4493|M.abscessus_ATCC_1997 LDDVRSTGVAFDHEEHDVGISSVAVPLPH--PAAIPQAMAIVAPTPRFAQ
MSMEG_6864|M.smegmatis_MC2_155 --VFHRRGEVLG----ALGVAGTDFTLAD-------QALDRVRAVVRSAA
* . *: . .: . *: . :
TH_3251|M.thermoresistible__bu DHRLVAPVRMAALGIWRAMEGARQRVVPTLQQVRPLRPGPTAQSLSHSAL
Mvan_4411|M.vanbaalenii_PYR-1 ----------------------RRFTVQLLKATEALSLG----SLRSA--
Mb3013|M.bovis_AF2122/97 RP-------------------GVRWAADLLSAADALTRRL----------
Rv2989|M.tuberculosis_H37Rv RP-------------------GVRWAADLLSAADALTRRL----------
MMAR_1725|M.marinum_M RP-------------------GARWAADLLAAADELARRL----------
MUL_1967|M.ulcerans_Agy99 RP-------------------GARWAADLLAAADELARRL----------
MAV_3839|M.avium_104 RP-------------------GARWAADLVSAAEALTRRL----------
Mflv_3087|M.gilvum_PYR-GCK DR-------------------FDEVAKQTVAAAEQISRRLGWTTRN----
MAB_4493|M.abscessus_ATCC_1997 RK------------------------TKYVAALDSLTKRANST-------
MSMEG_6864|M.smegmatis_MC2_155 AD------------------------ASAVLTAPSFGHRGTA--------
: :
TH_3251|M.thermoresistible__bu SHPAQSHPARSHRADTRRFA
Mvan_4411|M.vanbaalenii_PYR-1 --------------------
Mb3013|M.bovis_AF2122/97 --------------------
Rv2989|M.tuberculosis_H37Rv --------------------
MMAR_1725|M.marinum_M --------------------
MUL_1967|M.ulcerans_Agy99 --------------------
MAV_3839|M.avium_104 --------------------
Mflv_3087|M.gilvum_PYR-GCK --------------------
MAB_4493|M.abscessus_ATCC_1997 --------------------
MSMEG_6864|M.smegmatis_MC2_155 --------------------