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MDPVSQLEADARHLVRYSGRGGFTPTVIGSARGSLMFTEDGRELIDFTSGQMSAILGHSHPEIVATVQSQ IAHLDHLYSGMLSRPVIELSRRLAETLPPTLDKVLLLSTGAESNEAAVRMAKLVTGKHEIVSFARSWHGM TQAAANATYSAGRRGYGPAAPGNFALPVPHRFRPDITDELGELDWRRQLDLGFDLIDAQSVGSLAACLIE PILSSGGIIELPPGYLAALAQKCREREMLLIVDEAQTGLCRTGDWYAFEHDGVVPDILTLSKTLGAGLPL AAVITSSEIEQRAQEREFLFFTTHVNDPLPAAVGLTVLDVLSRDRLDVRARELGQRLRAGLDELAGRHPI VADVRGRGLLLGMELSAEDTPGVSADQLGAVVTRRCFELGLHMNIVQLPGMGGTFRLAPPLTATDNEIDR ALEIMDEALAYAREPAVHRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6842 | - | - | 100% (440) | 2,2-dialkylglycine decarboxylase |
| M. smegmatis MC2 155 | MSMEG_6685 | gabT | 2e-53 | 32.80% (436) | 4-aminobutyrate transaminase |
| M. smegmatis MC2 155 | MSMEG_0581 | gabT | 5e-51 | 31.36% (440) | 4-aminobutyrate transaminase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1683 | argD | 1e-46 | 33.33% (402) | acetylornithine aminotransferase |
| M. gilvum PYR-GCK | Mflv_0358 | - | 7e-52 | 30.84% (441) | hypothetical protein Mflv_0358 |
| M. tuberculosis H37Rv | Rv1655 | argD | 1e-46 | 33.33% (402) | acetylornithine aminotransferase |
| M. leprae Br4923 | MLBr_01409 | argD | 5e-46 | 30.77% (416) | acetylornithine aminotransferase |
| M. abscessus ATCC 19977 | MAB_4417c | - | 3e-59 | 35.02% (414) | aminotransferase |
| M. marinum M | MMAR_2118 | gabT | 3e-48 | 30.41% (434) | 4-aminobutyrate aminotransferase GabT |
| M. avium 104 | MAV_3470 | gabT | 1e-45 | 31.01% (416) | 4-aminobutyrate aminotransferase |
| M. thermoresistible (build 8) | TH_3529 | - | 2e-46 | 31.57% (415) | PUTATIVE aminotransferase |
| M. ulcerans Agy99 | MUL_1723 | gabT | 2e-47 | 30.18% (434) | 4-aminobutyrate aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_5803 | - | 1e-145 | 62.11% (417) | aminotransferase class-III |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2118|M.marinum_M ----------MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPV
MUL_1723|M.ulcerans_Agy99 ----------MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPV
MAV_3470|M.avium_104 ----------MARLEQTRRLVTEIPGPASLELSKRRAAAVSHAVNVSVPV
Mb1683|M.bovis_AF2122/97 ----------------------MTGASTTTATMRQRWQAVMMNNYGTPPI
Rv1655|M.tuberculosis_H37Rv ----------------------MTGASTTTATMRQRWQAVMMNNYGTPPI
MLBr_01409|M.leprae_Br4923 ----------------------MTPTQTNTATMQQRWETVMMNNYGTPPI
TH_3529|M.thermoresistible__bu -----------------------VSGSKGRHTLLDRWQGVMMNNYGTPPL
MSMEG_6842|M.smegmatis_MC2_155 ------------------------MDPVSQLEADARHLVRYSGRGGFTPT
Mvan_5803|M.vanbaalenii_PYR-1 ------------------------MSIEDFWRDAEHHLVRYG--GSFIPR
MAB_4417c|M.abscessus_ATCC_199 -------------------------------------------------M
Mflv_0358|M.gilvum_PYR-GCK MTITDQPTDTAGLPTGEDLDSAIARGRRAYDLDRRHVFHSWSAQAQITPM
MMAR_2118|M.marinum_M FVVRAGGGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTH
MUL_1723|M.ulcerans_Agy99 FVVRAGGGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTH
MAV_3470|M.avium_104 FVARAGGGIVEDVDGNRLIDLGSGIAVTTIGNSAPRVVDAVRAQVAEFTH
Mb1683|M.bovis_AF2122/97 ALASGDGAVVTDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGH
Rv1655|M.tuberculosis_H37Rv ALASGDGAVVTDVDGRTYIDLLGGIAVNVLGHRHPAVIEAVTRQMSTLGH
MLBr_01409|M.leprae_Br4923 VLASGNGAVVTDVDSNTYLDLLGGIAVNVLGHRHPAVIEAVTHQITTLGH
TH_3529|M.thermoresistible__bu ALVSGDGAVVTDADGKSYLDLLGGIAVNILGHRHPAVIEAVTRQLNTLGH
MSMEG_6842|M.smegmatis_MC2_155 VIGSARGSLMFTEDGRELIDFTSGQMSAILGHSHPEIVATVQSQIAHLDH
Mvan_5803|M.vanbaalenii_PYR-1 IIERACGSYVYDSAGTPILDFTSGQMSAVLGHAHPDIVATVSTAVGTLDH
MAB_4417c|M.abscessus_ATCC_199 VAARGQGCYLYDETDREYLDFTAGIGVVSTGHCHPRVVEAAQRQVATLIH
Mflv_0358|M.gilvum_PYR-GCK TVLAAQGSYVWDGDGTRLLDFSSQLVNTNIGHQHPKVVAAIAEQAATLCT
. * : . :*: . *: * :: : :
MMAR_2118|M.marinum_M TCFMVTPYEQYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAH
MUL_1723|M.ulcerans_Agy99 TCFMVIPYEHYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAH
MAV_3470|M.avium_104 TCFMVTPYESYVAVAETLNRITPGAGEKRSVLFNSGAEAVENAVKVARAY
Mb1683|M.bovis_AF2122/97 TSNLYAT-EPGIALAEELVALLGADQRTRVFFCNSGAEANEAAFKLSRLT
Rv1655|M.tuberculosis_H37Rv TSNLYAT-EPGIALAEELVALLGADQRTRVFFCNSGAEANEAAFKLSRLT
MLBr_01409|M.leprae_Br4923 TSNLYAT-EPSITLAEELVALLGADTQTRVFFCNSGTEANELAFKLSRLT
TH_3529|M.thermoresistible__bu TSNLYAT-EPGVALAEALVGHLGAP--ARVFFCNSGAEANEVAFKISRLT
MSMEG_6842|M.smegmatis_MC2_155 -LYSGMLSRPVIELSRRLAETLPPT-LDKVLLLSTGAESNEAAVRMAKLV
Mvan_5803|M.vanbaalenii_PYR-1 -LYSGMVSRPLVDLATTLTATLPAS-LSKVLLLTTGAESNEAAVKMAKLY
MAB_4417c|M.abscessus_ATCC_199 GQYTTVMHRPLQNLVRRLGEVLPPS-LNSLFFANSGSEAVEAAVRLARQA
Mflv_0358|M.gilvum_PYR-GCK -IAPQHVNDVRSEAARLIAERTPGD-LNRIFFTNGGADAVEHAVRMARLH
: .: . *::: * :.::::
MMAR_2118|M.marinum_M TRKQAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPY
MUL_1723|M.ulcerans_Agy99 TRKQAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPY
MAV_3470|M.avium_104 TRKPAVVAFDHAYHGRTNLAMALTAKSMPYKGGFGPFAPEIYRAPLSYPY
Mb1683|M.bovis_AF2122/97 G-RTKLVAAHDAFHGRTMGSLALTGQPAKQTP-FAPLPGDVTHVGYG---
Rv1655|M.tuberculosis_H37Rv G-RTKLVAAHDAFHGRTMGSLALTGQPAKQTP-FAPLPGDVTHVGYG---
MLBr_01409|M.leprae_Br4923 G-RTKLVAAQAAFHGRTMGSLALTGQPAKQAA-FEPLPGHVTHVPYG---
TH_3529|M.thermoresistible__bu G-RTKVVAAEGGFHGRTMGALALTGQPSKREP-FEPLPGDVIHVPYG---
MSMEG_6842|M.smegmatis_MC2_155 TGKHEIVSFARSWHGMTQAAANATYSAGRR--GYGPAAPGNFALPVPHRF
Mvan_5803|M.vanbaalenii_PYR-1 TGKYEIVSFDRSWHGMTSGAASVTFSAGRR--GYGPPMPGSLTLPTPNAY
MAB_4417c|M.abscessus_ATCC_199 TGRPNIIVFQGGFHGRTLAAATMTTSGPRFSSGIGPLMAGVYSAPFPTAY
Mflv_0358|M.gilvum_PYR-GCK TGRYKVLSRYRSYHGGTETAINLTGDPRRWPNDHGN--AGIVHFDGPFLY
: :: .:** * : * .
MMAR_2118|M.marinum_M RDNLLDKDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIVP
MUL_1723|M.ulcerans_Agy99 RDNLLDKDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIVP
MAV_3470|M.avium_104 RDGLLDKELATDGEKAAARAINIIDGQIGADSLAAVIIEPIQGEGGFIVP
Mb1683|M.bovis_AF2122/97 ---------------DVDALAAAVDDHT-----AAVFLEPIMGESGVVVP
Rv1655|M.tuberculosis_H37Rv ---------------DVDALAAAVDDHT-----AAVFLEPIMGESGVVVP
MLBr_01409|M.leprae_Br4923 ---------------QVDALAAAVDNDT-----AAVFLEPIMGESGVIVP
TH_3529|M.thermoresistible__bu ---------------DAGALERAVDDTT-----AAVFLEPIMGEGGVVVP
MSMEG_6842|M.smegmatis_MC2_155 RPDITDELGELDWRRQLDLGFDLIDAQS-VGSLAACLIEPILSSGGIIEL
Mvan_5803|M.vanbaalenii_PYR-1 RSPFRHADGSHDWLAELEYGFAMVDAQS-AGSLAACLVEPILSSGGIIEL
MAB_4417c|M.abscessus_ATCC_199 RYGWSEAEATRFALQELDYLFATATAP---GQVAAMVIEPVLGEGGYIPA
Mflv_0358|M.gilvum_PYR-GCK RSTFHADTEEQETQRALEHLDRLIRMEG-PSTIAAIILESVPGTAGIMVP
** .:*.: . .* :
MMAR_2118|M.marinum_M ADGFLPALQRWCRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDLI
MUL_1723|M.ulcerans_Agy99 ADGFLPALQRWSRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDLI
MAV_3470|M.avium_104 AEGFLPTLLDWCRRNDVLFIADEVQTGFARSGAMFACEHEGPNGLEPDLI
Mb1683|M.bovis_AF2122/97 PAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDG---ITPDVV
Rv1655|M.tuberculosis_H37Rv PAGYLAAARDITARRGALLVLDEVQTGMGRTGAFFAHQHDG---ITPDVV
MLBr_01409|M.leprae_Br4923 PEGYLAAARDITTRHGALLVIDEVQTGIGRTGAFFAHQHDS---ITPDVV
TH_3529|M.thermoresistible__bu PAGYLAAAREVTARHGALLVLDEVQTGIGRTGTFFAHQHDG---ITPDVV
MSMEG_6842|M.smegmatis_MC2_155 PPGYLAALAQKCREREMLLIVDEAQTGLCRTGDWYAFEHDG---VVPDIL
Mvan_5803|M.vanbaalenii_PYR-1 PPGYLRRLKELCAERGMLLILDEAQTGIARTGLMYAFERDG---VAPDLL
MAB_4417c|M.abscessus_ATCC_199 NTEFLTGIAERAREHGILLVLDEVQTGFGRTGQYFGHQHFG---VTPDVL
Mflv_0358|M.gilvum_PYR-GCK PPGYMAGVREICDRHGIVFIADEVMAGFGRTGTWFAIDNFG---VVPDLI
:: . ::: **. :*: *:* :. :. . : **::
MMAR_2118|M.marinum_M VTAKGIADG-FPLSAVTGRAEIMDAPHTS--GLGGTFGGNPVACAAALAT
MUL_1723|M.ulcerans_Agy99 VTAKGIADG-FPLSAVTGRAEIMDAPHTS--GLGGTFGGNPVACAAALAT
MAV_3470|M.avium_104 CTAKAIADG-LPLSAVTGRAQIMDAPHVG--GLGGTFGGNPLACAAALAT
Mb1683|M.bovis_AF2122/97 TLAKGLGGG-LPIGACLAVGPAAELLTPG--LHGSTFGGNPVCAAAALAV
Rv1655|M.tuberculosis_H37Rv TLAKGLGGG-LPIGACLAVGPAAELLTPG--LHGSTFGGNPVCAAAALAV
MLBr_01409|M.leprae_Br4923 TLAKGLGGG-LPIGAFLATGPAAELLTLG--LHGSTFGGNPVCTAAALAV
TH_3529|M.thermoresistible__bu TLAKGLGGG-LPIGACLAVGPAGDLLTPG--MHGSTFGGNPVCTAAAVAV
MSMEG_6842|M.smegmatis_MC2_155 TLSKTLGAG-LPLAAVITSSEIEQRAQEREFLFFTTHVNDPLPAAVGLTV
Mvan_5803|M.vanbaalenii_PYR-1 TLSKTLGAG-LPVAAVVTGEEIESTCHDRGFLFFTTHVSDPLAAAVACTV
MAB_4417c|M.abscessus_ATCC_199 VMAKGIASG-FPISGIAASAELMGRAWPG--SQGGTYGANAVACAAALAT
Mflv_0358|M.gilvum_PYR-GCK TFAKGVTSGYVPLGGVAINDAIYSTFADRAYPGGLTYSGHPLACACAVAT
:* : * .*:.. *. ..: * . :.
MMAR_2118|M.marinum_M IETIERDGMVERARQIERLVM-DRLLRLQAADDRLGDVRGRGAMIAMELV
MUL_1723|M.ulcerans_Agy99 IETIERDGMVERARQIERLVM-DRLLRLQAADDRLGDVRGRGAMIAMELV
MAV_3470|M.avium_104 IETIESDGLIERARQLERLIT-EPLLRLQARDDRIGDVRGRGAMIAIELV
Mb1683|M.bovis_AF2122/97 LRVLASDGLVRRAEVLGKSLR-HGIEALGHP--LIDHVRGRGLLLGIALT
Rv1655|M.tuberculosis_H37Rv LRVLASDGLVRRAEVLGKSLR-HGIEALGHP--LIDHVRGRGLLLGIALT
MLBr_01409|M.leprae_Br4923 LRVLATQGLVRRAEVLGDSMR-IGIESLSHP--LIDQVRGRGLLLGIVLT
TH_3529|M.thermoresistible__bu LGALAEGDLINRADVLGKKLS-HGIEELRHP--LVDHVRGRGLLCGVVLN
MSMEG_6842|M.smegmatis_MC2_155 LDVLSRDRLDVRARELGQRLR-AGLDELAGRHPIVADVRGRGLLLGMELS
Mvan_5803|M.vanbaalenii_PYR-1 LDVVARDGLVDRAERLGRQLG-ERLTDLKHRYDQVGDVRGRGLLQGLELV
MAB_4417c|M.abscessus_ATCC_199 LDVIDEEGLVDNARARGQELL-DGARKIAADRGIDGDVRGLGLMVGVEFS
Mflv_0358|M.gilvum_PYR-GCK ITAMEDEGMVANAARIGREVLGPGLRELAARHRSVGEVRGLGVFWAVELV
: .: : .* : : .*** * : .: :
MMAR_2118|M.marinum_M KSGTAEPDAALTQKLAAAAHAAG----VIVLTCGMFGNVIRLLPPLTISD
MUL_1723|M.ulcerans_Agy99 KSGTAEPDAALTQKLAAAAHAAG----VIVLTCGMFGNVIRLLPPLTISD
MAV_3470|M.avium_104 KSGTAEPDKDLTQRLSVAAHAAG----VIVLTCGMFGNIIRLLPPLTISD
Mb1683|M.bovis_AF2122/97 AP--------HAKDAEATARDAG----YLVN--AAAPDVIRLAPPLIIAE
Rv1655|M.tuberculosis_H37Rv AP--------HAKDAEATARDAG----YLVN--AAAPDVIRLAPPLIIAE
MLBr_01409|M.leprae_Br4923 AP--------RAKDIEKAARDAG----FLVN--ATAPEVIRLAPPLIITE
TH_3529|M.thermoresistible__bu AP--------QAKAAEAAARDAG----FLVN--AAAPEVIRLAPPLIITE
MSMEG_6842|M.smegmatis_MC2_155 AEDTPGVSADQLGAVVTRRCFELGLHMNIVQLPGMGG-TFRLAPPLTATD
Mvan_5803|M.vanbaalenii_PYR-1 VDKQTKEPADALGAEVTAACLDRGLHMNIVQLPGMGG-IFRIAPPLTITE
MAB_4417c|M.abscessus_ATCC_199 QDGRP---APQRAARAQAAAAENGLLLLMCG-PHMN--VVRMIPPLVVTA
Mflv_0358|M.gilvum_PYR-GCK ANQQTREPLAPYGGSSPAMNAVVAACKSGGLLPFANFNRIHAVPPCNVTD
.: ** :
MMAR_2118|M.marinum_M ELLSEGLDILCQILADL--------
MUL_1723|M.ulcerans_Agy99 ELLSEGLDILCQILADL--------
MAV_3470|M.avium_104 ELLAEGIDILGGLLADL--------
Mb1683|M.bovis_AF2122/97 AQLDGFVAALPAILDRAVGAP----
Rv1655|M.tuberculosis_H37Rv AQLDGFVAALPAILDRAVGAP----
MLBr_01409|M.leprae_Br4923 SQIDSFITALPGILDASIAELGKKA
TH_3529|M.thermoresistible__bu TQIDEFLAALPGVLDTAKEAS----
MSMEG_6842|M.smegmatis_MC2_155 NEIDRALEIMDEALAYAREPAVHRS
Mvan_5803|M.vanbaalenii_PYR-1 AELHSGLDILDESLKAVLQR-----
MAB_4417c|M.abscessus_ATCC_199 DQISDALGIWSSVVAGL--------
Mflv_0358|M.gilvum_PYR-GCK DEVAEGLRILDAALSVADDYTV---
: : :