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M. ulcerans Agy99 MUL_1723 (gabT)

annotation: 4-aminobutyrate aminotransferase
coordinates: 1902469 - 1903809
length: 446

ASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVVRAGGGIVEDADGNRLIDLGSGIAVTTIG
NSAPRVVDAVRDQVEQFTHTCFMVIPYEHYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHT
RKQAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPYRDNLLDKDIATDGELAAERAI
NLIDKQIGAANLAAVIIEPIAGEGGFIVPADGFLPALQRWSRDNDVVFIADEVQTGFARTGAMFACDHEN
VEPDLIVTAKGIADGFPLSAVTGRAEIMDAPHTSGLGGTFGGNPVACAAALATIETIERDGMVERARQIE
RLVMDRLLRLQAADDRLGDVRGRGAMIAMELVKSGTAEPDAALTQKLAAAAHAAGVIVLTCGMFGNVIRL
LPPLTISDELLSEGLDILCQILADL*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_1723gabT-100% (446)4-aminobutyrate aminotransferase
M. ulcerans Agy99MUL_1647argD1e-4534.75% (400) acetylornithine aminotransferase
M. ulcerans Agy99MUL_1243rocD2e-3929.75% (400) ornithine aminotransferase RocD1 and RocD2

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2620gabT0.083.30% (449) 4-aminobutyrate aminotransferase
M. gilvum PYR-GCKMflv_3818-0.075.78% (450) 4-aminobutyrate aminotransferase
M. tuberculosis H37RvRv2589gabT0.083.30% (449) 4-aminobutyrate aminotransferase
M. leprae Br4923MLBr_00485gabT0.081.12% (445) 4-aminobutyrate aminotransferase
M. abscessus ATCC 19977MAB_4207-1e-15564.09% (440) 4-aminobutyrate aminotransferase
M. marinum MMMAR_2118gabT0.099.33% (446) 4-aminobutyrate aminotransferase GabT
M. avium 104MAV_3470gabT0.081.96% (449) 4-aminobutyrate aminotransferase
M. smegmatis MC2 155MSMEG_2959gabT0.075.62% (443) 4-aminobutyrate aminotransferase
M. thermoresistible (build 8)TH_1978-4e-4632.80% (439) PROBABLE AMINOTRANSFERASE
M. vanbaalenii PYR-1Mvan_2581-0.076.01% (446) 4-aminobutyrate aminotransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3818|M.gilvum_PYR-GCK          ----MSALEQSRHLATAIPGPRSVELASRKNTAVSRGVGTTMPVYAARAF
Mvan_2581|M.vanbaalenii_PYR-1       ----MSALEQSRHLATAIPGPRSCELIARKSAAVARGVGTTMPVYAARAF
MSMEG_2959|M.smegmatis_MC2_155      ----MSHPEQSRHLATAIPGPRSQALIDRKGTAVARGVGTTMPVYAVRAG
MUL_1723|M.ulcerans_Agy99           ----MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVVRAG
MMAR_2118|M.marinum_M               ----MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVVRAG
Mb2620|M.bovis_AF2122/97            ----MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAG
Rv2589|M.tuberculosis_H37Rv         ----MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAG
MLBr_00485|M.leprae_Br4923          ----MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVTRAA
MAV_3470|M.avium_104                ----MARLEQTRRLVTEIPGPASLELSKRRAAAVSHAVNVSVPVFVARAG
MAB_4207|M.abscessus_ATCC_1997      MTDITYRLAQKRTIVTPLPGPRSGALAERRRAAVSAGVGSTAPVYAVDAD
TH_1978|M.thermoresistible__bu      -----------------MSTDRAAQADRHLWGHFARHGPGVTPPIIVRGD
                                                     :.   :     :    ..       *   . . 

Mflv_3818|M.gilvum_PYR-GCK          GGIVEDVDGNRLIDLGSGIAVTTVGNASPRVVAAVAEQAAEFTHTCFMVT
Mvan_2581|M.vanbaalenii_PYR-1       GGIVEDVDGNRLIDLGSGIAVTTIGNASPKVVERAAEQLHKFTHTCFMVT
MSMEG_2959|M.smegmatis_MC2_155      GGIVEDVDGNRLIDLGSGIAVTTVGNSAPKVVEAVRSQVGDFTHTCFMVT
MUL_1723|M.ulcerans_Agy99           GGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTHTCFMVI
MMAR_2118|M.marinum_M               GGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTHTCFMVT
Mb2620|M.bovis_AF2122/97            GGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVT
Rv2589|M.tuberculosis_H37Rv         GGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVT
MLBr_00485|M.leprae_Br4923          GGVIEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCFIIT
MAV_3470|M.avium_104                GGIVEDVDGNRLIDLGSGIAVTTIGNSAPRVVDAVRAQVAEFTHTCFMVT
MAB_4207|M.abscessus_ATCC_1997      GGVIVDADGNSFIDLGAGIAVTTVGASHPAVAAAIADQATHFTHTCFMVT
TH_1978|M.thermoresistible__bu      GVTIWDDHGRRYLDGLSGLFVVQAGHGRAELAEAAARQAGQLAYFPLWSY
                                    *  : * .*.  :*  :*: *.  * . . :.     *  .:::  :   

Mflv_3818|M.gilvum_PYR-GCK          PYEGYVAVAEALNRLTPGDGDKRSALFNSGSEAVENAVKIARTFT-----
Mvan_2581|M.vanbaalenii_PYR-1       PYEGYVAVAEALNRLTPGDGDKRTALFNSGSEAVENAVKIARSYT-----
MSMEG_2959|M.smegmatis_MC2_155      PYEGYVAVCEQLNRLTPVRGDKRSALFNSGSEAVENAVKIARSHT-----
MUL_1723|M.ulcerans_Agy99           PYEHYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHT-----
MMAR_2118|M.marinum_M               PYEQYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHT-----
Mb2620|M.bovis_AF2122/97            PYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYT-----
Rv2589|M.tuberculosis_H37Rv         PYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYT-----
MLBr_00485|M.leprae_Br4923          PYEEYVAVTEQLNRITPGSGEKRSVLFNSGAEAVENSIKVARSYT-----
MAV_3470|M.avium_104                PYESYVAVAETLNRITPGAGEKRSVLFNSGAEAVENAVKVARAYT-----
MAB_4207|M.abscessus_ATCC_1997      PYEGYVQVAELLNALTPGDHDKRTALFNSGAEAVENAIKVARLAT-----
TH_1978|M.thermoresistible__bu      ATPPAIELAERIAHYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKLTGK
                                    .    : : * :   :*     *  : ..*.****.: *:*:        

Mflv_3818|M.gilvum_PYR-GCK          -RKQAVVSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPMSYPF
Mvan_2581|M.vanbaalenii_PYR-1       -RKQAVVSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPLSYPF
MSMEG_2959|M.smegmatis_MC2_155      -HKPAVVAFDHAYHGRTNLTMALTAKVMPYKDGFGPFAPEIYRAPLSYPF
MUL_1723|M.ulcerans_Agy99           -RKQAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPY
MMAR_2118|M.marinum_M               -RKQAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPY
Mb2620|M.bovis_AF2122/97            -GKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPY
Rv2589|M.tuberculosis_H37Rv         -GKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPY
MLBr_00485|M.leprae_Br4923          -RKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPY
MAV_3470|M.avium_104                -RKPAVVAFDHAYHGRTNLAMALTAKSMPYKGGFGPFAPEIYRAPLSYPY
MAB_4207|M.abscessus_ATCC_1997      -GRPAVVAFDNAYHGRTNLTMALTAKSMPYKSQFGPFAPEVYRMPASYPL
TH_1978|M.thermoresistible__bu      PGKHKVVSRAVAYHGTPQGALAITGLPM-FKAPFEPLTPGGFRVPNTNFY
                                      :  **:   **** .: ::*:*.  * :*  * *::*  :* * :   

Mflv_3818|M.gilvum_PYR-GCK          RDAEFGGKELATDGELAARRAITVIDKQVGAGNLAAVIIEPIQGEGGFIV
Mvan_2581|M.vanbaalenii_PYR-1       RDAEFG-KELATDGELAARRAITVIDKQVGADNLAAVIIEPIQGEGGFIV
MSMEG_2959|M.smegmatis_MC2_155      RDAEFG-KELATDGELAAKRAITVIDKQIGADNLAAVVIEPIQGEGGFIV
MUL_1723|M.ulcerans_Agy99           RDNLLD-KDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIV
MMAR_2118|M.marinum_M               RDNLLD-KDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIV
Mb2620|M.bovis_AF2122/97            RDGLLD-KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIV
Rv2589|M.tuberculosis_H37Rv         RDGLLD-KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIV
MLBr_00485|M.leprae_Br4923          RDGLLN-KDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGFIV
MAV_3470|M.avium_104                RDGLLD-KELATDGEKAAARAINIIDGQIGADSLAAVIIEPIQGEGGFIV
MAB_4207|M.abscessus_ATCC_1997      RD------EPGLTGEEAARRAISRIETQIGAQSLAAIIIEPIQGEGGFIV
TH_1978|M.thermoresistible__bu      RAPAPYRDDEKAFGRYCADRIAETIEFE-GPDTVAAVVLEPVQNAGGCIP
                                    *       :    *. .. *    *: : *.  :**:::**: . ** * 

Mflv_3818|M.gilvum_PYR-GCK          PAEGFLPTLLDWCRANDVVFIADEVQTGFARTGAMFACEHEGPDGLVPDL
Mvan_2581|M.vanbaalenii_PYR-1       PAEGFLPTLLEWCHANGVVFIADEVQTGFARTGAMFACEHEG---IVPDL
MSMEG_2959|M.smegmatis_MC2_155      PADGFLPTLLDWCRKNDVVFIADEVQTGFARTGAMFACEHEG---IDPDL
MUL_1723|M.ulcerans_Agy99           PADGFLPALQRWSRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDL
MMAR_2118|M.marinum_M               PADGFLPALQRWCRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDL
Mb2620|M.bovis_AF2122/97            PAEGFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDL
Rv2589|M.tuberculosis_H37Rv         PAEGFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDL
MLBr_00485|M.leprae_Br4923          PAEGFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDG---IVPDL
MAV_3470|M.avium_104                PAEGFLPTLLDWCRRNDVLFIADEVQTGFARSGAMFACEHEGPNGLEPDL
MAB_4207|M.abscessus_ATCC_1997      PAPGFLATLTAWASENGVVFIADEVQTGFARTGAWFASEHEG---IVPDI
TH_1978|M.thermoresistible__bu      PPPGYFERVREICDTYDVLLISDEVICAFGRIGSMFACDDFG---YQPDI
                                    *. *::  :   .    *::*:***  .*.* *: **.:. .     **:

Mflv_3818|M.gilvum_PYR-GCK          IVTAKGIAGGMPLSAVTGRADIMDAPHVSG-----LGGTYGGNPVACAAA
Mvan_2581|M.vanbaalenii_PYR-1       IVTAKGIADGMPLSAVTGRAEIMDAPHVSG-----LGGTYGGNPVACAAA
MSMEG_2959|M.smegmatis_MC2_155      IVTAKGIAGGLPLSAVTGRAEIMDSPHVSG-----LGGTYGGNPIACAAA
MUL_1723|M.ulcerans_Agy99           IVTAKGIADGFPLSAVTGRAEIMDAPHTSG-----LGGTFGGNPVACAAA
MMAR_2118|M.marinum_M               IVTAKGIADGFPLSAVTGRAEIMDAPHTSG-----LGGTFGGNPVACAAA
Mb2620|M.bovis_AF2122/97            ICTAKGIADGLPLSAVTGRAEIMNAPHVGG-----LGGTFGGNPVACAAA
Rv2589|M.tuberculosis_H37Rv         ICTAKGIADGLPLSAVTGRAEIMNAPHVGG-----LGGTFGGNPVACAAA
MLBr_00485|M.leprae_Br4923          ICTAKGIADGLPLAAVTGRAEIMNAPHVSG-----LGGTFGGNPVACAAA
MAV_3470|M.avium_104                ICTAKAIADGLPLSAVTGRAQIMDAPHVGG-----LGGTFGGNPLACAAA
MAB_4207|M.abscessus_ATCC_1997      VTMAKGIAGGMPLSAVTGRAELMDAVYAGG-----LGGTYGGNPVTCAAA
TH_1978|M.thermoresistible__bu      ITCAKGLTSGYAPLGAMIATDRLFEPFADGKTVFPHGYTFGGHPVSAAVA
                                    :  **.::.* .  ..   :: :   ...*      * *:**:*::.*.*

Mflv_3818|M.gilvum_PYR-GCK          LATIETIESDNLVARAAQIEALMKDRLGRMQAEDDRIGDVRGRGAMIAVE
Mvan_2581|M.vanbaalenii_PYR-1       LATIETIESDGLVARAAQIETLMKDKLGRLQAEDDRIGDVRGRGAMIAVE
MSMEG_2959|M.smegmatis_MC2_155      LATIETIESEGLVARAQQIEKIMKDRLGRLQAEDDRIGDVRGRGAMIAME
MUL_1723|M.ulcerans_Agy99           LATIETIERDGMVERARQIERLVMDRLLRLQAADDRLGDVRGRGAMIAME
MMAR_2118|M.marinum_M               LATIETIERDGMVERARQIERLVMDRLLRLQAADDRLGDVRGRGAMIAME
Mb2620|M.bovis_AF2122/97            LATIATIESDGLIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVE
Rv2589|M.tuberculosis_H37Rv         LATIATIESDGLIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVE
MLBr_00485|M.leprae_Br4923          LATITTIENDGLIQRAQQIERLITDRLLRLQDADDRIGDVRGRGAMIAVE
MAV_3470|M.avium_104                LATIETIESDGLIERARQLERLITEPLLRLQARDDRIGDVRGRGAMIAIE
MAB_4207|M.abscessus_ATCC_1997      VAALGVMRELDLPARARAIEASVTSRLSALAEEVDIIGEVRGRGAMLAIE
TH_1978|M.thermoresistible__bu      LANLDIFEREGLNDRVRTLSPLLRATLERLYELP-IVGDVRGEGYFFAVE
                                    :* :  :.  .:  *.  :.  :   *  :      :*:***.* ::*:*

Mflv_3818|M.gilvum_PYR-GCK          LVKSGT------LEPDPELTRKLLTAAHAAGVIVLSCGTFGNVLRFLPPL
Mvan_2581|M.vanbaalenii_PYR-1       LVKPGT------LEPDPELTKNLLAAAHRAGVIVLSCGTFGNVLRFLPPL
MSMEG_2959|M.smegmatis_MC2_155      LVKAGT------TEPDADLTKALCAGAHAAGVIVLSCGTYGNVVRFLPPL
MUL_1723|M.ulcerans_Agy99           LVKSGT------AEPDAALTQKLAAAAHAAGVIVLTCGMFGNVIRLLPPL
MMAR_2118|M.marinum_M               LVKSGT------AEPDAALTQKLAAAAHAAGVIVLTCGMFGNVIRLLPPL
Mb2620|M.bovis_AF2122/97            LVKSGT------TEPDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPL
Rv2589|M.tuberculosis_H37Rv         LVKSGT------TEPDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPL
MLBr_00485|M.leprae_Br4923          LVKSGT------AEPDPELTEKVATAAHATGVIILTCGMFGNIIRLLPPL
MAV_3470|M.avium_104                LVKSGT------AEPDKDLTQRLSVAAHAAGVIVLTCGMFGNIIRLLPPL
MAB_4207|M.abscessus_ATCC_1997      IVKPGT------LEPDAALTKSIAAEALSQGVLILTCGTFGNVIRLLPPL
TH_1978|M.thermoresistible__bu      LVQDKAGRQPFSAEESARLVAHLNRALLDAGLYCRADNRGDTVVQVAPPL
                                    :*:  :       * .  *.  :       *:   : .  ..:::. ***

Mflv_3818|M.gilvum_PYR-GCK          AISDDLLLEGLDILELILRDL----
Mvan_2581|M.vanbaalenii_PYR-1       AISDELLLEGLDVLELILRDL----
MSMEG_2959|M.smegmatis_MC2_155      SIGDDLLNEGLDVLEEVLRGA----
MUL_1723|M.ulcerans_Agy99           TISDELLSEGLDILCQILADL----
MMAR_2118|M.marinum_M               TISDELLSEGLDILCQILADL----
Mb2620|M.bovis_AF2122/97            TIGDELLSEGLDIVCAILADL----
Rv2589|M.tuberculosis_H37Rv         TIGDELLSEGLDIVCAILADL----
MLBr_00485|M.leprae_Br4923          TISDELLAEGLDILSRILGDF----
MAV_3470|M.avium_104                TISDELLAEGIDILGGLLADL----
MAB_4207|M.abscessus_ATCC_1997      VIGDDLLDEGITALSDIIRAKASHQ
TH_1978|M.thermoresistible__bu      ISGPAEFDAMHDILRTVLKDAPNHV
                                      .   :      :  ::