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SIEDFWRDAEHHLVRYGGSFIPRIIERACGSYVYDSAGTPILDFTSGQMSAVLGHAHPDIVATVSTAVGT LDHLYSGMVSRPLVDLATTLTATLPASLSKVLLLTTGAESNEAAVKMAKLYTGKYEIVSFDRSWHGMTSG AASVTFSAGRRGYGPPMPGSLTLPTPNAYRSPFRHADGSHDWLAELEYGFAMVDAQSAGSLAACLVEPIL SSGGIIELPPGYLRRLKELCAERGMLLILDEAQTGIARTGLMYAFERDGVAPDLLTLSKTLGAGLPVAAV VTGEEIESTCHDRGFLFFTTHVSDPLAAAVACTVLDVVARDGLVDRAERLGRQLGERLTDLKHRYDQVGD VRGRGLLQGLELVVDKQTKEPADALGAEVTAACLDRGLHMNIVQLPGMGGIFRIAPPLTITEAELHSGLD ILDESLKAVLQR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5803 | - | - | 100% (433) | aminotransferase class-III |
| M. vanbaalenii PYR-1 | Mvan_1823 | - | 1e-57 | 33.73% (415) | hypothetical protein Mvan_1823 |
| M. vanbaalenii PYR-1 | Mvan_3311 | argD | 1e-52 | 34.31% (408) | acetylornithine aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2620 | gabT | 4e-52 | 34.61% (419) | 4-aminobutyrate aminotransferase |
| M. gilvum PYR-GCK | Mflv_0358 | - | 5e-58 | 33.49% (415) | hypothetical protein Mflv_0358 |
| M. tuberculosis H37Rv | Rv2589 | gabT | 4e-52 | 34.61% (419) | 4-aminobutyrate aminotransferase |
| M. leprae Br4923 | MLBr_00485 | gabT | 2e-54 | 33.98% (415) | 4-aminobutyrate aminotransferase |
| M. abscessus ATCC 19977 | MAB_4417c | - | 9e-58 | 34.63% (410) | aminotransferase |
| M. marinum M | MMAR_2118 | gabT | 2e-54 | 34.22% (415) | 4-aminobutyrate aminotransferase GabT |
| M. avium 104 | MAV_3470 | gabT | 9e-53 | 35.04% (411) | 4-aminobutyrate aminotransferase |
| M. smegmatis MC2 155 | MSMEG_6842 | - | 1e-145 | 62.11% (417) | 2,2-dialkylglycine decarboxylase |
| M. thermoresistible (build 8) | TH_3529 | - | 3e-49 | 33.42% (398) | PUTATIVE aminotransferase |
| M. ulcerans Agy99 | MUL_1723 | gabT | 2e-53 | 33.98% (415) | 4-aminobutyrate aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5803|M.vanbaalenii_PYR-1 ------------------------MSIEDFWRDAEHHLVRYGG--SFIPR
MSMEG_6842|M.smegmatis_MC2_155 ------------------------MDPVSQLEADARHLVRYSGRGGFTPT
MAB_4417c|M.abscessus_ATCC_199 -------------------------------------------------M
Mb2620|M.bovis_AF2122/97 ----------MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPV
Rv2589|M.tuberculosis_H37Rv ----------MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPV
MLBr_00485|M.leprae_Br4923 ----------MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPV
MAV_3470|M.avium_104 ----------MARLEQTRRLVTEIPGPASLELSKRRAAAVSHAVNVSVPV
MMAR_2118|M.marinum_M ----------MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPV
MUL_1723|M.ulcerans_Agy99 ----------MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPV
Mflv_0358|M.gilvum_PYR-GCK MTITDQPTDTAGLPTGEDLDSAIARGRRAYDLDRRHVFHSWSAQAQITPM
TH_3529|M.thermoresistible__bu --------------------VSGSKGRHTLLDRWQGVMMNN---YGTPPL
Mvan_5803|M.vanbaalenii_PYR-1 IIERACGSYVYDSAGTPILDFTSGQMSAVLGHAHPDIVATVSTAVGTLDH
MSMEG_6842|M.smegmatis_MC2_155 VIGSARGSLMFTEDGRELIDFTSGQMSAILGHSHPEIVATVQSQIAHLDH
MAB_4417c|M.abscessus_ATCC_199 VAARGQGCYLYDETDREYLDFTAGIGVVSTGHCHPRVVEAAQRQVATLIH
Mb2620|M.bovis_AF2122/97 FVARAGGGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTH
Rv2589|M.tuberculosis_H37Rv FVARAGGGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTH
MLBr_00485|M.leprae_Br4923 FVTRAAGGVIEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTH
MAV_3470|M.avium_104 FVARAGGGIVEDVDGNRLIDLGSGIAVTTIGNSAPRVVDAVRAQVAEFTH
MMAR_2118|M.marinum_M FVVRAGGGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTH
MUL_1723|M.ulcerans_Agy99 FVVRAGGGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTH
Mflv_0358|M.gilvum_PYR-GCK TVLAAQGSYVWDGDGTRLLDFSSQLVNTNIGHQHPKVVAAIAEQAATLCT
TH_3529|M.thermoresistible__bu ALVSGDGAVVTDADGKSYLDLLGGIAVNILGHRHPAVIEAVTRQLNTLGH
. * : . :*: . *: * :: : :
Mvan_5803|M.vanbaalenii_PYR-1 -LYSGMVSRPLVDLATTLTATLPAS-LSKVLLLTTGAESNEAAVKMAKLY
MSMEG_6842|M.smegmatis_MC2_155 -LYSGMLSRPVIELSRRLAETLPPT-LDKVLLLSTGAESNEAAVRMAKLV
MAB_4417c|M.abscessus_ATCC_199 GQYTTVMHRPLQNLVRRLGEVLPPS-LNSLFFANSGSEAVEAAVRLARQA
Mb2620|M.bovis_AF2122/97 TCFMVTPYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSY
Rv2589|M.tuberculosis_H37Rv TCFMVTPYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSY
MLBr_00485|M.leprae_Br4923 TCFIITPYEEYVAVTEQLNRITPGSGEKRSVLFNSGAEAVENSIKVARSY
MAV_3470|M.avium_104 TCFMVTPYESYVAVAETLNRITPGAGEKRSVLFNSGAEAVENAVKVARAY
MMAR_2118|M.marinum_M TCFMVTPYEQYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAH
MUL_1723|M.ulcerans_Agy99 TCFMVIPYEHYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAH
Mflv_0358|M.gilvum_PYR-GCK --IAPQHVNDVRSEAARLIAERTPGDLNRIFFTNGGADAVEHAVRMARLH
TH_3529|M.thermoresistible__bu --TSNLYATEPGVALAEALVG-HLGAPARVFFCNSGAEANEVAFKISRLT
.: . *::: * :.::::
Mvan_5803|M.vanbaalenii_PYR-1 TGKYEIVSFDRSWHGMTSGAASVTFSAGRR--GYGPPMPGSLTLPTPNAY
MSMEG_6842|M.smegmatis_MC2_155 TGKHEIVSFARSWHGMTQAAANATYSAGRR--GYGPAAPGNFALPVPHRF
MAB_4417c|M.abscessus_ATCC_199 TGRPNIIVFQGGFHGRTLAAATMTTSGPRFSSGIGPLMAGVYSAPFPTAY
Mb2620|M.bovis_AF2122/97 TGKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPY
Rv2589|M.tuberculosis_H37Rv TGKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPY
MLBr_00485|M.leprae_Br4923 TRKPAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPY
MAV_3470|M.avium_104 TRKPAVVAFDHAYHGRTNLAMALTAKSMPYKGGFGPFAPEIYRAPLSYPY
MMAR_2118|M.marinum_M TRKQAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPY
MUL_1723|M.ulcerans_Agy99 TRKQAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPY
Mflv_0358|M.gilvum_PYR-GCK TGRYKVLSRYRSYHGGTETAINLTGDPRRWPNDHGNAGIVHFDGPFLYRS
TH_3529|M.thermoresistible__bu G-RTKVVAAEGGFHGRTMGALALTGQPSKRE------PFEPLPGDVIHVP
: :: .:** * : * .
Mvan_5803|M.vanbaalenii_PYR-1 RSPFRHADGSHDWLAELEYGFAMVDAQS-AGSLAACLVEPILSSGGIIEL
MSMEG_6842|M.smegmatis_MC2_155 RPDITDELGELDWRRQLDLGFDLIDAQS-VGSLAACLIEPILSSGGIIEL
MAB_4417c|M.abscessus_ATCC_199 RYGWSEAEATRFALQELDYLFATATAP---GQVAAMVIEPVLGEGGYIPA
Mb2620|M.bovis_AF2122/97 RDGLLDKQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVP
Rv2589|M.tuberculosis_H37Rv RDGLLDKQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVP
MLBr_00485|M.leprae_Br4923 RDGLLNKDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGFIVP
MAV_3470|M.avium_104 RDGLLDKELATDGEKAAARAINIIDGQIGADSLAAVIIEPIQGEGGFIVP
MMAR_2118|M.marinum_M RDNLLDKDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIVP
MUL_1723|M.ulcerans_Agy99 RDNLLDKDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIVP
Mflv_0358|M.gilvum_PYR-GCK ---TFHADTEEQETQRALEHLDRLIRMEGPSTIAAIILESVPGTAGIMVP
TH_3529|M.thermoresistible__bu ---YGDAGALERAVD---------------DTTAAVFLEPIMGEGGVVVP
. ** .:*.: . .* :
Mvan_5803|M.vanbaalenii_PYR-1 PPGYLRRLKELCAERGMLLILDEAQTGIARTGLMYAFERDG---VAPDLL
MSMEG_6842|M.smegmatis_MC2_155 PPGYLAALAQKCREREMLLIVDEAQTGLCRTGDWYAFEHDG---VVPDIL
MAB_4417c|M.abscessus_ATCC_199 NTEFLTGIAERAREHGILLVLDEVQTGFGRTGQYFGHQHFG---VTPDVL
Mb2620|M.bovis_AF2122/97 AEGFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLI
Rv2589|M.tuberculosis_H37Rv AEGFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLI
MLBr_00485|M.leprae_Br4923 AEGFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDG---IVPDLI
MAV_3470|M.avium_104 AEGFLPTLLDWCRRNDVLFIADEVQTGFARSGAMFACEHEGPNGLEPDLI
MMAR_2118|M.marinum_M ADGFLPALQRWCRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDLI
MUL_1723|M.ulcerans_Agy99 ADGFLPALQRWSRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDLI
Mflv_0358|M.gilvum_PYR-GCK PPGYMAGVREICDRHGIVFIADEVMAGFGRTGTWFAIDNFG---VVPDLI
TH_3529|M.thermoresistible__bu PAGYLAAAREVTARHGALLVLDEVQTGIGRTGTFFAHQHDG---ITPDVV
:: . ::: **. :*: *:* :. :. . : **::
Mvan_5803|M.vanbaalenii_PYR-1 TLSKTLGAG-LPVAAVVTGEEIESTCHDRGFLFFTTHVSDPLAAAVACTV
MSMEG_6842|M.smegmatis_MC2_155 TLSKTLGAG-LPLAAVITSSEIEQRAQEREFLFFTTHVNDPLPAAVGLTV
MAB_4417c|M.abscessus_ATCC_199 VMAKGIASG-FPISGIAASAELMGRAWPG--SQGGTYGANAVACAAALAT
Mb2620|M.bovis_AF2122/97 CTAKGIADG-LPLSAVTGRAEIMNAPHVGG--LGGTFGGNPVACAAALAT
Rv2589|M.tuberculosis_H37Rv CTAKGIADG-LPLSAVTGRAEIMNAPHVGG--LGGTFGGNPVACAAALAT
MLBr_00485|M.leprae_Br4923 CTAKGIADG-LPLAAVTGRAEIMNAPHVSG--LGGTFGGNPVACAAALAT
MAV_3470|M.avium_104 CTAKAIADG-LPLSAVTGRAQIMDAPHVGG--LGGTFGGNPLACAAALAT
MMAR_2118|M.marinum_M VTAKGIADG-FPLSAVTGRAEIMDAPHTSG--LGGTFGGNPVACAAALAT
MUL_1723|M.ulcerans_Agy99 VTAKGIADG-FPLSAVTGRAEIMDAPHTSG--LGGTFGGNPVACAAALAT
Mflv_0358|M.gilvum_PYR-GCK TFAKGVTSGYVPLGGVAINDAIYSTFADRAYPGGLTYSGHPLACACAVAT
TH_3529|M.thermoresistible__bu TLAKGLGGG-LPIGACLAVGPAGDLLTPGMH--GSTFGGNPVCTAAAVAV
:* : * .*:.. *. ..: * . :.
Mvan_5803|M.vanbaalenii_PYR-1 LDVVARDGLVDRAERLGRQLGER-LTDLKHRYDQVGDVRGRGLLQGLELV
MSMEG_6842|M.smegmatis_MC2_155 LDVLSRDRLDVRARELGQRLRAG-LDELAGRHPIVADVRGRGLLLGMELS
MAB_4417c|M.abscessus_ATCC_199 LDVIDEEGLVDNARARGQELLDG-ARKIAADRGIDGDVRGLGLMVGVEFS
Mb2620|M.bovis_AF2122/97 IATIESDGLIERARQIERLVTDR-LTTLQAVDDRIGDVRGRGAMIAVELV
Rv2589|M.tuberculosis_H37Rv IATIESDGLIERARQIERLVTDR-LTTLQAVDDRIGDVRGRGAMIAVELV
MLBr_00485|M.leprae_Br4923 ITTIENDGLIQRAQQIERLITDR-LLRLQDADDRIGDVRGRGAMIAVELV
MAV_3470|M.avium_104 IETIESDGLIERARQLERLITEP-LLRLQARDDRIGDVRGRGAMIAIELV
MMAR_2118|M.marinum_M IETIERDGMVERARQIERLVMDR-LLRLQAADDRLGDVRGRGAMIAMELV
MUL_1723|M.ulcerans_Agy99 IETIERDGMVERARQIERLVMDR-LLRLQAADDRLGDVRGRGAMIAMELV
Mflv_0358|M.gilvum_PYR-GCK ITAMEDEGMVANAARIGREVLGPGLRELAARHRSVGEVRGLGVFWAVELV
TH_3529|M.thermoresistible__bu LGALAEGDLINRADVLGKKLSHG---IEELRHPLVDHVRGRGLLCGVVLN
: .: : .* : : .*** * : .: :
Mvan_5803|M.vanbaalenii_PYR-1 VDKQTKE-----PADALGAEVTAACLDRGLHMNIVQLPGMGGIFRIAPPL
MSMEG_6842|M.smegmatis_MC2_155 AEDTPGV-----SADQLGAVVTRRCFELGLHMNIVQLPGMGGTFRLAPPL
MAB_4417c|M.abscessus_ATCC_199 QDGRP--------APQRAARAQAAAAENGLLLLMCG-PHMN-VVRMIPPL
Mb2620|M.bovis_AF2122/97 KSGTTE------PDAGLTERLATAAHAAGVIILTCG--MFGNIIRLLPPL
Rv2589|M.tuberculosis_H37Rv KSGTTE------PDAGLTERLATAAHAAGVIILTCG--MFGNIIRLLPPL
MLBr_00485|M.leprae_Br4923 KSGTAE------PDPELTEKVATAAHATGVIILTCG--MFGNIIRLLPPL
MAV_3470|M.avium_104 KSGTAE------PDKDLTQRLSVAAHAAGVIVLTCG--MFGNIIRLLPPL
MMAR_2118|M.marinum_M KSGTAE------PDAALTQKLAAAAHAAGVIVLTCG--MFGNVIRLLPPL
MUL_1723|M.ulcerans_Agy99 KSGTAE------PDAALTQKLAAAAHAAGVIVLTCG--MFGNVIRLLPPL
Mflv_0358|M.gilvum_PYR-GCK ANQQTREPLAPYGGSSPAMNAVVAACKSGGLLPFAN----FNRIHAVPPC
TH_3529|M.thermoresistible__bu APQAK--------------AAEAAARDAGFLVNAAA----PEVIRLAPPL
. * : .: **
Mvan_5803|M.vanbaalenii_PYR-1 TITEAELHSGLDILDESLKAVLQR-----
MSMEG_6842|M.smegmatis_MC2_155 TATDNEIDRALEIMDEALAYAREPAVHRS
MAB_4417c|M.abscessus_ATCC_199 VVTADQISDALGIWSSVVAGL--------
Mb2620|M.bovis_AF2122/97 TIGDELLSEGLDIVCAILADL--------
Rv2589|M.tuberculosis_H37Rv TIGDELLSEGLDIVCAILADL--------
MLBr_00485|M.leprae_Br4923 TISDELLAEGLDILSRILGDF--------
MAV_3470|M.avium_104 TISDELLAEGIDILGGLLADL--------
MMAR_2118|M.marinum_M TISDELLSEGLDILCQILADL--------
MUL_1723|M.ulcerans_Agy99 TISDELLSEGLDILCQILADL--------
Mflv_0358|M.gilvum_PYR-GCK NVTDDEVAEGLRILDAALSVADDYTV---
TH_3529|M.thermoresistible__bu IITETQIDEFLAALPGVLDTAKEAS----
: : :