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M. smegmatis MC2 155 MSMEG_0581 (gabT)

annotation: 4-aminobutyrate transaminase
coordinates: 657676 - 659022
length: 448

VTIAEIAGRTLTQERRLVTAIPGPISQELQARKQSAVAAGVGVTLPVYVVAAGGGVLADADGNQLIDFGS
GIAVTTVGNSAPAVVDAVTQQVAAFTHTCFMVTPYEGYVKVAEHLNRLTPGDHEKRTALFNSGAEAVENA
VKIARAYTRRQAVVVFDHAYHGRTNLTMAMTAKNQPYKHGFGPFANEVYRVPTSYPFRDGETDGAAAAAH
ALDLINKQVGADNVAAVVIEPVHGEGGFVVPAPGFLGALQKWCTDNGAVFVADEVQTGFARTGALFACEH
ENVVPDLIVTAKGIAGGLPLSAVTGRAEIMDGPQSGGLGGTYGGNPLACAAALAVIDTIERENLVARARA
IGETMLSRLGALAAADPRIGEVRGRGAMIAVELVKPGTTEPDADLTKRVAAAAHAQGLVVLTCGTYGNVL
RFLPPLSMPDHLLDEGLDILAAVFAEVK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_0581gabT-100% (448)4-aminobutyrate transaminase
M. smegmatis MC2 155MSMEG_2959gabTe-18072.08% (437) 4-aminobutyrate aminotransferase
M. smegmatis MC2 155MSMEG_6685gabTe-15660.94% (448) 4-aminobutyrate transaminase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2620gabT1e-17668.68% (447) 4-aminobutyrate aminotransferase
M. gilvum PYR-GCKMflv_3818-1e-17869.35% (447) 4-aminobutyrate aminotransferase
M. tuberculosis H37RvRv2589gabT1e-17668.68% (447) 4-aminobutyrate aminotransferase
M. leprae Br4923MLBr_00485gabT1e-17365.91% (443) 4-aminobutyrate aminotransferase
M. abscessus ATCC 19977MAB_4207-1e-16264.75% (434) 4-aminobutyrate aminotransferase
M. marinum MMMAR_2118gabT0.069.82% (444) 4-aminobutyrate aminotransferase GabT
M. avium 104MAV_3470gabT1e-17066.14% (446) 4-aminobutyrate aminotransferase
M. thermoresistible (build 8)TH_3529-2e-5335.71% (406) PUTATIVE aminotransferase
M. ulcerans Agy99MUL_1723gabT1e-17969.37% (444) 4-aminobutyrate aminotransferase
M. vanbaalenii PYR-1Mvan_2581-0.070.43% (443) 4-aminobutyrate aminotransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2620|M.bovis_AF2122/97            -------MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVA
Rv2589|M.tuberculosis_H37Rv         -------MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVA
MLBr_00485|M.leprae_Br4923          -------MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVT
MAV_3470|M.avium_104                -------MARLEQTRRLVTEIPGPASLELSKRRAAAVSHAVNVSVPVFVA
MMAR_2118|M.marinum_M               -------MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVV
MUL_1723|M.ulcerans_Agy99           -------MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVV
Mflv_3818|M.gilvum_PYR-GCK          -------MSALEQSRHLATAIPGPRSVELASRKNTAVSRGVGTTMPVYAA
Mvan_2581|M.vanbaalenii_PYR-1       -------MSALEQSRHLATAIPGPRSCELIARKSAAVARGVGTTMPVYAA
MSMEG_0581|M.smegmatis_MC2_155      MTIAEIAGRTLTQERRLVTAIPGPISQELQARKQSAVAAGVGVTLPVYVV
MAB_4207|M.abscessus_ATCC_1997      ---MTDITYRLAQKRTIVTPLPGPRSGALAERRRAAVSAGVGSTAPVYAV
TH_3529|M.thermoresistible__bu      --------------------VSGSKGRHTLLDRWQGVMMNNYGTPPLALV
                                                        :.*. .         .*      : *:  .

Mb2620|M.bovis_AF2122/97            RAGGGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCF
Rv2589|M.tuberculosis_H37Rv         RAGGGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCF
MLBr_00485|M.leprae_Br4923          RAAGGVIEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCF
MAV_3470|M.avium_104                RAGGGIVEDVDGNRLIDLGSGIAVTTIGNSAPRVVDAVRAQVAEFTHTCF
MMAR_2118|M.marinum_M               RAGGGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTHTCF
MUL_1723|M.ulcerans_Agy99           RAGGGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTHTCF
Mflv_3818|M.gilvum_PYR-GCK          RAFGGIVEDVDGNRLIDLGSGIAVTTVGNASPRVVAAVAEQAAEFTHTCF
Mvan_2581|M.vanbaalenii_PYR-1       RAFGGIVEDVDGNRLIDLGSGIAVTTIGNASPKVVERAAEQLHKFTHTCF
MSMEG_0581|M.smegmatis_MC2_155      AAGGGVLADADGNQLIDFGSGIAVTTVGNSAPAVVDAVTQQVAAFTHTCF
MAB_4207|M.abscessus_ATCC_1997      DADGGVIVDADGNSFIDLGAGIAVTTVGASHPAVAAAIADQATHFTHTCF
TH_3529|M.thermoresistible__bu      SGDGAVVTDADGKSYLDLLGGIAVNILGHRHPAVIEAVTRQLNTLGHTSN
                                     . *.:: *.**:  :*: .****. :*   * *      *   : **. 

Mb2620|M.bovis_AF2122/97            MVTPYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGK
Rv2589|M.tuberculosis_H37Rv         MVTPYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGK
MLBr_00485|M.leprae_Br4923          IITPYEEYVAVTEQLNRITPGSGEKRSVLFNSGAEAVENSIKVARSYTRK
MAV_3470|M.avium_104                MVTPYESYVAVAETLNRITPGAGEKRSVLFNSGAEAVENAVKVARAYTRK
MMAR_2118|M.marinum_M               MVTPYEQYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHTRK
MUL_1723|M.ulcerans_Agy99           MVIPYEHYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHTRK
Mflv_3818|M.gilvum_PYR-GCK          MVTPYEGYVAVAEALNRLTPGDGDKRSALFNSGSEAVENAVKIARTFTRK
Mvan_2581|M.vanbaalenii_PYR-1       MVTPYEGYVAVAEALNRLTPGDGDKRTALFNSGSEAVENAVKIARSYTRK
MSMEG_0581|M.smegmatis_MC2_155      MVTPYEGYVKVAEHLNRLTPGDHEKRTALFNSGAEAVENAVKIARAYTRR
MAB_4207|M.abscessus_ATCC_1997      MVTPYEGYVQVAELLNALTPGDHDKRTALFNSGAEAVENAIKVARLATGR
TH_3529|M.thermoresistible__bu      LYATEPGVALAEALVGHLG---APARVFFCNSGAEANEVAFKISR-LTGR
                                    :  .    . .   :. :       *  : ***:** * :.*::*  * :

Mb2620|M.bovis_AF2122/97            PAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDG
Rv2589|M.tuberculosis_H37Rv         PAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDG
MLBr_00485|M.leprae_Br4923          PAVVAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDG
MAV_3470|M.avium_104                PAVVAFDHAYHGRTNLAMALTAKSMPYKGGFGPFAPEIYRAPLSYPYRDG
MMAR_2118|M.marinum_M               QAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPYRDN
MUL_1723|M.ulcerans_Agy99           QAVVAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPYRDN
Mflv_3818|M.gilvum_PYR-GCK          QAVVSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPMSYPFRDA
Mvan_2581|M.vanbaalenii_PYR-1       QAVVSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPLSYPFRDA
MSMEG_0581|M.smegmatis_MC2_155      QAVVVFDHAYHGRTNLTMAMTAKNQPYKHGFGPFANEVYRVPTSYPFRD-
MAB_4207|M.abscessus_ATCC_1997      PAVVAFDNAYHGRTNLTMALTAKSMPYKSQFGPFAPEVYRMPASYPLRD-
TH_3529|M.thermoresistible__bu      TKVVAAEGGFHGRTMGALALTGQP-SKREPFEPLPGDVIHVPYG------
                                      **  : .:****  ::*:*.:  . :  * *:. :: : * .      

Mb2620|M.bovis_AF2122/97            LLD-KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAE
Rv2589|M.tuberculosis_H37Rv         LLD-KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAE
MLBr_00485|M.leprae_Br4923          LLN-KDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGFIVPAE
MAV_3470|M.avium_104                LLD-KELATDGEKAAARAINIIDGQIGADSLAAVIIEPIQGEGGFIVPAE
MMAR_2118|M.marinum_M               LLD-KDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIVPAD
MUL_1723|M.ulcerans_Agy99           LLD-KDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIVPAD
Mflv_3818|M.gilvum_PYR-GCK          EFGGKELATDGELAARRAITVIDKQVGAGNLAAVIIEPIQGEGGFIVPAE
Mvan_2581|M.vanbaalenii_PYR-1       EFG-KELATDGELAARRAITVIDKQVGADNLAAVIIEPIQGEGGFIVPAE
MSMEG_0581|M.smegmatis_MC2_155      --G----ETDGAAAAAHALDLINKQVGADNVAAVVIEPVHGEGGFVVPAP
MAB_4207|M.abscessus_ATCC_1997      -----EPGLTGEEAARRAISRIETQIGAQSLAAIIIEPIQGEGGFIVPAP
TH_3529|M.thermoresistible__bu      ----------DAGALERAV--------DDTTAAVFLEPIMGEGGVVVPPA
                                              .  *  :*:            **:.:**: ****.:**. 

Mb2620|M.bovis_AF2122/97            GFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICT
Rv2589|M.tuberculosis_H37Rv         GFLPALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICT
MLBr_00485|M.leprae_Br4923          GFLATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDG---IVPDLICT
MAV_3470|M.avium_104                GFLPTLLDWCRRNDVLFIADEVQTGFARSGAMFACEHEGPNGLEPDLICT
MMAR_2118|M.marinum_M               GFLPALQRWCRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDLIVT
MUL_1723|M.ulcerans_Agy99           GFLPALQRWSRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDLIVT
Mflv_3818|M.gilvum_PYR-GCK          GFLPTLLDWCRANDVVFIADEVQTGFARTGAMFACEHEGPDGLVPDLIVT
Mvan_2581|M.vanbaalenii_PYR-1       GFLPTLLEWCHANGVVFIADEVQTGFARTGAMFACEHEG---IVPDLIVT
MSMEG_0581|M.smegmatis_MC2_155      GFLGALQKWCTDNGAVFVADEVQTGFARTGALFACEHEN---VVPDLIVT
MAB_4207|M.abscessus_ATCC_1997      GFLATLTAWASENGVVFIADEVQTGFARTGAWFASEHEG---IVPDIVTM
TH_3529|M.thermoresistible__bu      GYLAAAREVTARHGALLVLDEVQTGIGRTGTFFAHQHDG---ITPDVVTL
                                    *:* :       : .::: ******:.*:*: ** :*:.   : **::  

Mb2620|M.bovis_AF2122/97            AKGIADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIE
Rv2589|M.tuberculosis_H37Rv         AKGIADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIE
MLBr_00485|M.leprae_Br4923          AKGIADGLPLAAVTGRAEIMNAPHVSGLGGTFGGNPVACAAALATITTIE
MAV_3470|M.avium_104                AKAIADGLPLSAVTGRAQIMDAPHVGGLGGTFGGNPLACAAALATIETIE
MMAR_2118|M.marinum_M               AKGIADGFPLSAVTGRAEIMDAPHTSGLGGTFGGNPVACAAALATIETIE
MUL_1723|M.ulcerans_Agy99           AKGIADGFPLSAVTGRAEIMDAPHTSGLGGTFGGNPVACAAALATIETIE
Mflv_3818|M.gilvum_PYR-GCK          AKGIAGGMPLSAVTGRADIMDAPHVSGLGGTYGGNPVACAAALATIETIE
Mvan_2581|M.vanbaalenii_PYR-1       AKGIADGMPLSAVTGRAEIMDAPHVSGLGGTYGGNPVACAAALATIETIE
MSMEG_0581|M.smegmatis_MC2_155      AKGIAGGLPLSAVTGRAEIMDGPQSGGLGGTYGGNPLACAAALAVIDTIE
MAB_4207|M.abscessus_ATCC_1997      AKGIAGGMPLSAVTGRAELMDAVYAGGLGGTYGGNPVTCAAAVAALGVMR
TH_3529|M.thermoresistible__bu      AKGLGGGLPIGACLAVGPAGDLLTPGMHGSTFGGNPVCTAAAVAVLGALA
                                    **.:..*:*:.*  . .   :    .  *.*:****:  ***:*.: .: 

Mb2620|M.bovis_AF2122/97            SDGLIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSGTTE
Rv2589|M.tuberculosis_H37Rv         SDGLIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSGTTE
MLBr_00485|M.leprae_Br4923          NDGLIQRAQQIERLITDRLLRLQDADDRIGDVRGRGAMIAVELVKSGTAE
MAV_3470|M.avium_104                SDGLIERARQLERLITEPLLRLQARDDRIGDVRGRGAMIAIELVKSGTAE
MMAR_2118|M.marinum_M               RDGMVERARQIERLVMDRLLRLQAADDRLGDVRGRGAMIAMELVKSGTAE
MUL_1723|M.ulcerans_Agy99           RDGMVERARQIERLVMDRLLRLQAADDRLGDVRGRGAMIAMELVKSGTAE
Mflv_3818|M.gilvum_PYR-GCK          SDNLVARAAQIEALMKDRLGRMQAEDDRIGDVRGRGAMIAVELVKSGTLE
Mvan_2581|M.vanbaalenii_PYR-1       SDGLVARAAQIETLMKDKLGRLQAEDDRIGDVRGRGAMIAVELVKPGTLE
MSMEG_0581|M.smegmatis_MC2_155      RENLVARARAIGETMLSRLGALAAADPRIGEVRGRGAMIAVELVKPGTTE
MAB_4207|M.abscessus_ATCC_1997      ELDLPARARAIEASVTSRLSALAEEVDIIGEVRGRGAMLAIEIVKPGTLE
TH_3529|M.thermoresistible__bu      EGDLINRADVLGKKLSHGIEELRHP--LVDHVRGRGLLCGVVLNAP----
                                      .:  **  :   :   :  :      :..***** : .: :  .    

Mb2620|M.bovis_AF2122/97            PDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLDIV
Rv2589|M.tuberculosis_H37Rv         PDAGLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLDIV
MLBr_00485|M.leprae_Br4923          PDPELTEKVATAAHATGVIILTCGMFGNIIRLLPPLTISDELLAEGLDIL
MAV_3470|M.avium_104                PDKDLTQRLSVAAHAAGVIVLTCGMFGNIIRLLPPLTISDELLAEGIDIL
MMAR_2118|M.marinum_M               PDAALTQKLAAAAHAAGVIVLTCGMFGNVIRLLPPLTISDELLSEGLDIL
MUL_1723|M.ulcerans_Agy99           PDAALTQKLAAAAHAAGVIVLTCGMFGNVIRLLPPLTISDELLSEGLDIL
Mflv_3818|M.gilvum_PYR-GCK          PDPELTRKLLTAAHAAGVIVLSCGTFGNVLRFLPPLAISDDLLLEGLDIL
Mvan_2581|M.vanbaalenii_PYR-1       PDPELTKNLLAAAHRAGVIVLSCGTFGNVLRFLPPLAISDELLLEGLDVL
MSMEG_0581|M.smegmatis_MC2_155      PDADLTKRVAAAAHAQGLVVLTCGTYGNVLRFLPPLSMPDHLLDEGLDIL
MAB_4207|M.abscessus_ATCC_1997      PDAALTKSIAAEALSQGVLILTCGTFGNVIRLLPPLVIGDDLLDEGITAL
TH_3529|M.thermoresistible__bu      ------QAKAAEAAARDAGFLVNAAAPEVIRLAPPLIITETQIDEFLAAL
                                          .   . *   .  .*  .   :::*: *** : :  : * :  :

Mb2620|M.bovis_AF2122/97            CAILADL----
Rv2589|M.tuberculosis_H37Rv         CAILADL----
MLBr_00485|M.leprae_Br4923          SRILGDF----
MAV_3470|M.avium_104                GGLLADL----
MMAR_2118|M.marinum_M               CQILADL----
MUL_1723|M.ulcerans_Agy99           CQILADL----
Mflv_3818|M.gilvum_PYR-GCK          ELILRDL----
Mvan_2581|M.vanbaalenii_PYR-1       ELILRDL----
MSMEG_0581|M.smegmatis_MC2_155      AAVFAEVK---
MAB_4207|M.abscessus_ATCC_1997      SDIIRAKASHQ
TH_3529|M.thermoresistible__bu      PGVLDTAKEAS
                                      ::