For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. avium 104 MAV_3470 (gabT)

annotation: 4-aminobutyrate aminotransferase
coordinates: 3618144 - 3619493
length: 449

VARLEQTRRLVTEIPGPASLELSKRRAAAVSHAVNVSVPVFVARAGGGIVEDVDGNRLIDLGSGIAVTTI
GNSAPRVVDAVRAQVAEFTHTCFMVTPYESYVAVAETLNRITPGAGEKRSVLFNSGAEAVENAVKVARAY
TRKPAVVAFDHAYHGRTNLAMALTAKSMPYKGGFGPFAPEIYRAPLSYPYRDGLLDKELATDGEKAAARA
INIIDGQIGADSLAAVIIEPIQGEGGFIVPAEGFLPTLLDWCRRNDVLFIADEVQTGFARSGAMFACEHE
GPNGLEPDLICTAKAIADGLPLSAVTGRAQIMDAPHVGGLGGTFGGNPLACAAALATIETIESDGLIERA
RQLERLITEPLLRLQARDDRIGDVRGRGAMIAIELVKSGTAEPDKDLTQRLSVAAHAAGVIVLTCGMFGN
IIRLLPPLTISDELLAEGIDILGGLLADL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. avium 104MAV_3470gabT-100% (449)4-aminobutyrate aminotransferase
M. avium 104MAV_3115argD2e-4834.32% (437) acetylornithine aminotransferase
M. avium 104MAV_4304-5e-4032.73% (443) hypothetical protein MAV_4304

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2620gabT0.085.08% (449) 4-aminobutyrate aminotransferase
M. gilvum PYR-GCKMflv_3818-0.076.67% (450) 4-aminobutyrate aminotransferase
M. tuberculosis H37RvRv2589gabT0.085.08% (449) 4-aminobutyrate aminotransferase
M. leprae Br4923MLBr_00485gabT0.081.47% (448) 4-aminobutyrate aminotransferase
M. abscessus ATCC 19977MAB_4207-1e-15161.71% (444) 4-aminobutyrate aminotransferase
M. marinum MMMAR_2118gabT0.082.41% (449) 4-aminobutyrate aminotransferase GabT
M. smegmatis MC2 155MSMEG_2959gabT0.074.66% (446) 4-aminobutyrate aminotransferase
M. thermoresistible (build 8)TH_3529-1e-4533.99% (409) PUTATIVE aminotransferase
M. ulcerans Agy99MUL_1723gabT0.081.96% (449) 4-aminobutyrate aminotransferase
M. vanbaalenii PYR-1Mvan_2581-0.075.28% (449) 4-aminobutyrate aminotransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3818|M.gilvum_PYR-GCK          ----MSALEQSRHLATAIPGPRSVELASRKNTAVSRGVGTTMPVYAARAF
Mvan_2581|M.vanbaalenii_PYR-1       ----MSALEQSRHLATAIPGPRSCELIARKSAAVARGVGTTMPVYAARAF
MSMEG_2959|M.smegmatis_MC2_155      ----MSHPEQSRHLATAIPGPRSQALIDRKGTAVARGVGTTMPVYAVRAG
Mb2620|M.bovis_AF2122/97            ----MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAG
Rv2589|M.tuberculosis_H37Rv         ----MASLQQSRRLVTEIPGPASQALTHRRAAAVSSGVGVTLPVFVARAG
MLBr_00485|M.leprae_Br4923          ----MTSVEQSRQLVTEIPGPVSLELAKRLNAAVPRGVGVTLPVFVTRAA
MAV_3470|M.avium_104                ----MARLEQTRRLVTEIPGPASLELSKRRAAAVSHAVNVSVPVFVARAG
MMAR_2118|M.marinum_M               ----MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVVRAG
MUL_1723|M.ulcerans_Agy99           ----MASLDQSRLLVTEIPGPASLELNKRRAAAVSGGVGVTLPVFVVRAG
MAB_4207|M.abscessus_ATCC_1997      MTDITYRLAQKRTIVTPLPGPRSGALAERRRAAVSAGVGSTAPVYAVDAD
TH_3529|M.thermoresistible__bu      -----------------VSGSKGRHTLLDRWQGVMMNNYGTPPLALVSGD
                                                     :.*. .         .*      : *:  . . 

Mflv_3818|M.gilvum_PYR-GCK          GGIVEDVDGNRLIDLGSGIAVTTVGNASPRVVAAVAEQAAEFTHTCFMVT
Mvan_2581|M.vanbaalenii_PYR-1       GGIVEDVDGNRLIDLGSGIAVTTIGNASPKVVERAAEQLHKFTHTCFMVT
MSMEG_2959|M.smegmatis_MC2_155      GGIVEDVDGNRLIDLGSGIAVTTVGNSAPKVVEAVRSQVGDFTHTCFMVT
Mb2620|M.bovis_AF2122/97            GGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVT
Rv2589|M.tuberculosis_H37Rv         GGIVEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRTQVAEFTHTCFMVT
MLBr_00485|M.leprae_Br4923          GGVIEDVDGNRLIDLGSGIAVTTIGNSSPRVVDAVRAQVADFTHTCFIIT
MAV_3470|M.avium_104                GGIVEDVDGNRLIDLGSGIAVTTIGNSAPRVVDAVRAQVAEFTHTCFMVT
MMAR_2118|M.marinum_M               GGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTHTCFMVT
MUL_1723|M.ulcerans_Agy99           GGIVEDADGNRLIDLGSGIAVTTIGNSAPRVVDAVRDQVEQFTHTCFMVI
MAB_4207|M.abscessus_ATCC_1997      GGVIVDADGNSFIDLGAGIAVTTVGASHPAVAAAIADQATHFTHTCFMVT
TH_3529|M.thermoresistible__bu      GAVVTDADGKSYLDLLGGIAVNILGHRHPAVIEAVTRQLNTLGHTSNLYA
                                    *.:: *.**:  :** .****. :*   * *      *   : **. :  

Mflv_3818|M.gilvum_PYR-GCK          PYEGYVAVAEALNRLTPGDGDKRSALFNSGSEAVENAVKIARTFTRKQAV
Mvan_2581|M.vanbaalenii_PYR-1       PYEGYVAVAEALNRLTPGDGDKRTALFNSGSEAVENAVKIARSYTRKQAV
MSMEG_2959|M.smegmatis_MC2_155      PYEGYVAVCEQLNRLTPVRGDKRSALFNSGSEAVENAVKIARSHTHKPAV
Mb2620|M.bovis_AF2122/97            PYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGKPAV
Rv2589|M.tuberculosis_H37Rv         PYEGYVAVAEQLNRITPGSGPKRSVLFNSGAEAVENAVKIARSYTGKPAV
MLBr_00485|M.leprae_Br4923          PYEEYVAVTEQLNRITPGSGEKRSVLFNSGAEAVENSIKVARSYTRKPAV
MAV_3470|M.avium_104                PYESYVAVAETLNRITPGAGEKRSVLFNSGAEAVENAVKVARAYTRKPAV
MMAR_2118|M.marinum_M               PYEQYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHTRKQAV
MUL_1723|M.ulcerans_Agy99           PYEHYVAVAEQLNRITPGSGEKRTVLFNSGAEAVENSIKVARAHTRKQAV
MAB_4207|M.abscessus_ATCC_1997      PYEGYVQVAELLNALTPGDHDKRTALFNSGAEAVENAIKVARLATGRPAV
TH_3529|M.thermoresistible__bu      TEPGVALAEALVGHLG---APARVFFCNSGAEANEVAFKISR-LTGRTKV
                                    .    . .   :. :       *  : ***:** * :.*::*  * :  *

Mflv_3818|M.gilvum_PYR-GCK          VSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPMSYPFRDAEFG
Mvan_2581|M.vanbaalenii_PYR-1       VSFDHAYHGRTNLTMALTAKSMPYKHGFGPFAPEIYRAPLSYPFRDAEFG
MSMEG_2959|M.smegmatis_MC2_155      VAFDHAYHGRTNLTMALTAKVMPYKDGFGPFAPEIYRAPLSYPFRDAEFG
Mb2620|M.bovis_AF2122/97            VAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDGLLD
Rv2589|M.tuberculosis_H37Rv         VAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDGLLD
MLBr_00485|M.leprae_Br4923          VAFDHAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPLSYPYRDGLLN
MAV_3470|M.avium_104                VAFDHAYHGRTNLAMALTAKSMPYKGGFGPFAPEIYRAPLSYPYRDGLLD
MMAR_2118|M.marinum_M               VAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPYRDNLLD
MUL_1723|M.ulcerans_Agy99           VAFDYAYHGRTNLTMALTAKSMPYKSGFGPFAPEIYRAPVSYPYRDNLLD
MAB_4207|M.abscessus_ATCC_1997      VAFDNAYHGRTNLTMALTAKSMPYKSQFGPFAPEVYRMPASYPLRD----
TH_3529|M.thermoresistible__bu      VAAEGGFHGRTMGALALTGQPSKREP-FEPLPGDVIHVPYG---------
                                    *: : .:****  ::***.:    :  * *:. :: : * .         

Mflv_3818|M.gilvum_PYR-GCK          GKELATDGELAARRAITVIDKQVGAGNLAAVIIEPIQGEGGFIVPAEGFL
Mvan_2581|M.vanbaalenii_PYR-1       -KELATDGELAARRAITVIDKQVGADNLAAVIIEPIQGEGGFIVPAEGFL
MSMEG_2959|M.smegmatis_MC2_155      -KELATDGELAAKRAITVIDKQIGADNLAAVVIEPIQGEGGFIVPADGFL
Mb2620|M.bovis_AF2122/97            -KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAEGFL
Rv2589|M.tuberculosis_H37Rv         -KQLATNGELAAARAIGVIDKQVGANNLAALVIEPIQGEGGFIVPAEGFL
MLBr_00485|M.leprae_Br4923          -KDLATDGKLAGARAINVIEKQVGADDLAAVIIEPIQGEGGFIVPAEGFL
MAV_3470|M.avium_104                -KELATDGEKAAARAINIIDGQIGADSLAAVIIEPIQGEGGFIVPAEGFL
MMAR_2118|M.marinum_M               -KDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIVPADGFL
MUL_1723|M.ulcerans_Agy99           -KDIATDGELAAERAINLIDKQIGAANLAAVIIEPIAGEGGFIVPADGFL
MAB_4207|M.abscessus_ATCC_1997      --EPGLTGEEAARRAISRIETQIGAQSLAAIIIEPIQGEGGFIVPAPGFL
TH_3529|M.thermoresistible__bu      -------DAGALERAV--------DDTTAAVFLEPIMGEGGVVVPPAGYL
                                           .  *  **:            **:.:*** ****.:**. *:*

Mflv_3818|M.gilvum_PYR-GCK          PTLLDWCRANDVVFIADEVQTGFARTGAMFACEHEGPDGLVPDLIVTAKG
Mvan_2581|M.vanbaalenii_PYR-1       PTLLEWCHANGVVFIADEVQTGFARTGAMFACEHEG---IVPDLIVTAKG
MSMEG_2959|M.smegmatis_MC2_155      PTLLDWCRKNDVVFIADEVQTGFARTGAMFACEHEG---IDPDLIVTAKG
Mb2620|M.bovis_AF2122/97            PALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICTAKG
Rv2589|M.tuberculosis_H37Rv         PALLDWCRKNHVVFIADEVQTGFARTGAMFACEHEGPDGLEPDLICTAKG
MLBr_00485|M.leprae_Br4923          ATLLDWCRKNNVMFIADEVQTGFARTGAMFACEHDG---IVPDLICTAKG
MAV_3470|M.avium_104                PTLLDWCRRNDVLFIADEVQTGFARSGAMFACEHEGPNGLEPDLICTAKA
MMAR_2118|M.marinum_M               PALQRWCRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDLIVTAKG
MUL_1723|M.ulcerans_Agy99           PALQRWSRDNDVVFIADEVQTGFARTGAMFACDHEN---VEPDLIVTAKG
MAB_4207|M.abscessus_ATCC_1997      ATLTAWASENGVVFIADEVQTGFARTGAWFASEHEG---IVPDIVTMAKG
TH_3529|M.thermoresistible__bu      AAAREVTARHGALLVLDEVQTGIGRTGTFFAHQHDG---ITPDVVTLAKG
                                    .:       : .::: ******:.*:*: ** :*:.   : **::  **.

Mflv_3818|M.gilvum_PYR-GCK          IAGGMPLSAVTGRADIMDAPHVSGLGGTYGGNPVACAAALATIETIESDN
Mvan_2581|M.vanbaalenii_PYR-1       IADGMPLSAVTGRAEIMDAPHVSGLGGTYGGNPVACAAALATIETIESDG
MSMEG_2959|M.smegmatis_MC2_155      IAGGLPLSAVTGRAEIMDSPHVSGLGGTYGGNPIACAAALATIETIESEG
Mb2620|M.bovis_AF2122/97            IADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIESDG
Rv2589|M.tuberculosis_H37Rv         IADGLPLSAVTGRAEIMNAPHVGGLGGTFGGNPVACAAALATIATIESDG
MLBr_00485|M.leprae_Br4923          IADGLPLAAVTGRAEIMNAPHVSGLGGTFGGNPVACAAALATITTIENDG
MAV_3470|M.avium_104                IADGLPLSAVTGRAQIMDAPHVGGLGGTFGGNPLACAAALATIETIESDG
MMAR_2118|M.marinum_M               IADGFPLSAVTGRAEIMDAPHTSGLGGTFGGNPVACAAALATIETIERDG
MUL_1723|M.ulcerans_Agy99           IADGFPLSAVTGRAEIMDAPHTSGLGGTFGGNPVACAAALATIETIERDG
MAB_4207|M.abscessus_ATCC_1997      IAGGMPLSAVTGRAELMDAVYAGGLGGTYGGNPVTCAAAVAALGVMRELD
TH_3529|M.thermoresistible__bu      LGGGLPIGACLAVGPAGDLLTPGMHGSTFGGNPVCTAAAVAVLGALAEGD
                                    :..*:*:.*  . .   :    .  *.*:****:  ***:*.: .:   .

Mflv_3818|M.gilvum_PYR-GCK          LVARAAQIEALMKDRLGRMQAEDDRIGDVRGRGAMIAVELVKSGTLEPDP
Mvan_2581|M.vanbaalenii_PYR-1       LVARAAQIETLMKDKLGRLQAEDDRIGDVRGRGAMIAVELVKPGTLEPDP
MSMEG_2959|M.smegmatis_MC2_155      LVARAQQIEKIMKDRLGRLQAEDDRIGDVRGRGAMIAMELVKAGTTEPDA
Mb2620|M.bovis_AF2122/97            LIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSGTTEPDA
Rv2589|M.tuberculosis_H37Rv         LIERARQIERLVTDRLTTLQAVDDRIGDVRGRGAMIAVELVKSGTTEPDA
MLBr_00485|M.leprae_Br4923          LIQRAQQIERLITDRLLRLQDADDRIGDVRGRGAMIAVELVKSGTAEPDP
MAV_3470|M.avium_104                LIERARQLERLITEPLLRLQARDDRIGDVRGRGAMIAIELVKSGTAEPDK
MMAR_2118|M.marinum_M               MVERARQIERLVMDRLLRLQAADDRLGDVRGRGAMIAMELVKSGTAEPDA
MUL_1723|M.ulcerans_Agy99           MVERARQIERLVMDRLLRLQAADDRLGDVRGRGAMIAMELVKSGTAEPDA
MAB_4207|M.abscessus_ATCC_1997      LPARARAIEASVTSRLSALAEEVDIIGEVRGRGAMLAIEIVKPGTLEPDA
TH_3529|M.thermoresistible__bu      LINRADVLGKKLSHGIEELRHP--LVDHVRGRGLLCGVVLNAP-------
                                    :  **  :   :   :  :      :..***** : .: :  .       

Mflv_3818|M.gilvum_PYR-GCK          ELTRKLLTAAHAAGVIVLSCGTFGNVLRFLPPLAISDDLLLEGLDILELI
Mvan_2581|M.vanbaalenii_PYR-1       ELTKNLLAAAHRAGVIVLSCGTFGNVLRFLPPLAISDELLLEGLDVLELI
MSMEG_2959|M.smegmatis_MC2_155      DLTKALCAGAHAAGVIVLSCGTYGNVVRFLPPLSIGDDLLNEGLDVLEEV
Mb2620|M.bovis_AF2122/97            GLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLDIVCAI
Rv2589|M.tuberculosis_H37Rv         GLTERLATAAHAAGVIILTCGMFGNIIRLLPPLTIGDELLSEGLDIVCAI
MLBr_00485|M.leprae_Br4923          ELTEKVATAAHATGVIILTCGMFGNIIRLLPPLTISDELLAEGLDILSRI
MAV_3470|M.avium_104                DLTQRLSVAAHAAGVIVLTCGMFGNIIRLLPPLTISDELLAEGIDILGGL
MMAR_2118|M.marinum_M               ALTQKLAAAAHAAGVIVLTCGMFGNVIRLLPPLTISDELLSEGLDILCQI
MUL_1723|M.ulcerans_Agy99           ALTQKLAAAAHAAGVIVLTCGMFGNVIRLLPPLTISDELLSEGLDILCQI
MAB_4207|M.abscessus_ATCC_1997      ALTKSIAAEALSQGVLILTCGTFGNVIRLLPPLVIGDDLLDEGITALSDI
TH_3529|M.thermoresistible__bu      ---QAKAAEAAARDAGFLVNAAAPEVIRLAPPLIITETQIDEFLAALPGV
                                       .   . *   .. .*  .   :::*: *** * :  : * :  :  :

Mflv_3818|M.gilvum_PYR-GCK          LRDL----
Mvan_2581|M.vanbaalenii_PYR-1       LRDL----
MSMEG_2959|M.smegmatis_MC2_155      LRGA----
Mb2620|M.bovis_AF2122/97            LADL----
Rv2589|M.tuberculosis_H37Rv         LADL----
MLBr_00485|M.leprae_Br4923          LGDF----
MAV_3470|M.avium_104                LADL----
MMAR_2118|M.marinum_M               LADL----
MUL_1723|M.ulcerans_Agy99           LADL----
MAB_4207|M.abscessus_ATCC_1997      IRAKASHQ
TH_3529|M.thermoresistible__bu      LDTAKEAS
                                    :