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VSGNESKTGIMRILSTSSIGAMLEYYDFFVYVALTGTLTELFLPAGDRTVAMLLGAATFGVSYLARPLGT VIFSPMSDRIGRKKTFVVTLAVMGVATVAIGCLPTYAAIGVWAPAMLLFLRIVQGVGLGGEYGSAVVYVT EHAPAERRGRYTSVLQSTATVGLLFALVLVSLLKVLLSDEAFTSWGWRVPFLVSAPIVLVATLIRLRMQE TPVFTALQDSGQLSKTPLLDTVRTWSSWKSILLGTFGAQGGTSVTLYTSIIYMLYFLQHVLEVDQTHTNL CLAVAIVIAAPCYPMFGAWSDRVGRSRVMLTGIVLWMLAAYPAFAGIRTAVGSSSWVTVSALISVLAVLT AMVMAPLPAFITEQFPPQSRTTGFGFAQQLGNILFGGFLPLISLSLVDATGNQLAGVGYSIVSLVPCLAV TLFWGLRSERSRRHDISAASALSVRREPQTL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6775 | - | - | 100% (451) | major facilitator superfamily protein transporter |
| M. smegmatis MC2 155 | MSMEG_3992 | - | 6e-68 | 36.49% (422) | integral membrane transport protein |
| M. smegmatis MC2 155 | MSMEG_4886 | - | 5e-67 | 36.17% (423) | major facilitator family protein transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1232 | - | 7e-49 | 32.06% (418) | integral membrane transport protein |
| M. gilvum PYR-GCK | Mflv_2383 | - | 7e-68 | 35.53% (425) | major facilitator transporter |
| M. tuberculosis H37Rv | Rv1200 | - | 7e-49 | 32.06% (418) | integral membrane transport protein |
| M. leprae Br4923 | MLBr_01562 | - | 4e-09 | 28.42% (183) | putative transmembrane efflux protein |
| M. abscessus ATCC 19977 | MAB_2263c | - | 7e-59 | 31.91% (423) | major facilitator transporter |
| M. marinum M | MMAR_4238 | - | 7e-46 | 31.87% (411) | integral membrane transport protein |
| M. avium 104 | MAV_4627 | - | 2e-67 | 33.41% (422) | major facilitator superfamily protein |
| M. thermoresistible (build 8) | TH_3722 | - | 5e-66 | 34.14% (413) | PUTATIVE General substrate transporter |
| M. ulcerans Agy99 | MUL_0949 | - | 2e-45 | 31.63% (411) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_4266 | - | 1e-66 | 35.47% (406) | general substrate transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1232|M.bovis_AF2122/97 ----------------------------------------------MKRV
Rv1200|M.tuberculosis_H37Rv ----------------------------------------------MKRV
MMAR_4238|M.marinum_M ----------------------------------------------MSRV
MUL_0949|M.ulcerans_Agy99 ----------------------------------------------MSRV
Mflv_2383|M.gilvum_PYR-GCK -----------------------------MGPGG-------RTRVSPRRV
MAV_4627|M.avium_104 -----------------MAATLPAPAPAGLADGHPLDESAEQQRRRLRIV
TH_3722|M.thermoresistible__bu --------------------VSENPSIVSAPPAP--------DAVVIRKA
Mvan_4266|M.vanbaalenii_PYR-1 -----------------------MTVKETRPAAP--------GAVSR--A
MAB_2263c|M.abscessus_ATCC_199 -----------------MSSAGPREGETEPPPVPRPDFQSPEGRRQLHRA
MSMEG_6775|M.smegmatis_MC2_155 -----------------------MSGNES--------------KTGIMRI
MLBr_01562|M.leprae_Br4923 MVTLYDHERAVHNWTAARSDRPAPSRLTQQVEPASERTSKYPTLLPSGRF
Mb1232|M.bovis_AF2122/97 ALACLVGSAIEFYDFLIYGTAAALVFPTVFFPHLDPTVAAVASMGTFAVA
Rv1200|M.tuberculosis_H37Rv ALACLVGSAIEFYDFLIYGTAAALVFPTVFFPHLDPTVAAVASMGTFAVA
MMAR_4238|M.marinum_M ALACVVGSTVEYYDFCIYGTAAALVFPAVFYPGLSPALATIASMGTFATA
MUL_0949|M.ulcerans_Agy99 ALACVVGSTVEYYDFCIYGTAAALVFPAVFYPGLSPALATIASMGTFATA
Mflv_2383|M.gilvum_PYR-GCK AIASFVGTTVEFYDFLIYGTAAALVFPKLFFPNASPAAGILLSFATFGVG
MAV_4627|M.avium_104 VAASLLGTTVEWYDFFLYATAAGLVFNKVFFPNESSLVGTLLAFATFAVG
TH_3722|M.thermoresistible__bu VTGASIGNAVEWFDFAIYGFLATYIA-ANFFPAGDDTAALLNTFAIFAAA
Mvan_4266|M.vanbaalenii_PYR-1 VRGAAIGNAVEWFDFAIYGFLATYIA-EKFFPPGDETAALLNTFAIFAAA
MAB_2263c|M.abscessus_ATCC_199 IAASAMGNATEWYDYGVYAATTTFLT-QAFFPTLGTAFTMLG----YAIS
MSMEG_6775|M.smegmatis_MC2_155 LSTSSIGAMLEYYDFFVYVALTGTLT-ELFLPAGDRTVAMLLGAATFGVS
MLBr_01562|M.leprae_Br4923 PSGRFIAAVIVIGGMQLLATMDSTVA-IVALPKIQNELSLSDAGRSWGIT
:. . : : * :.
Mb1232|M.bovis_AF2122/97 FLSRPFGAAVFG--YFGDRLGRKKTLVATLLIMGLATVTVG---------
Rv1200|M.tuberculosis_H37Rv FLSRPFGAAVFG--YFGDRLGRKKTLVATLLIMGLATVTVG---------
MMAR_4238|M.marinum_M FLSRPLGAAVFG--HFGDRLGRKKTLVATLLIMALSTVTVG---------
MUL_0949|M.ulcerans_Agy99 FLSRPLGAAVFG--HFGDRLGRKKTLVATLLIMALSTVTVG---------
Mflv_2383|M.gilvum_PYR-GCK FIARPLGGIVFG--HFGDRVGRRRMLVYSLVGMGVSTVLIG---------
MAV_4627|M.avium_104 FVMRPIGGLVFG--HIGDRIGRKRSLALTMLIMGGATALIG---------
TH_3722|M.thermoresistible__bu FVVRPLGGFFFG--PLGDRIGRQRVLALVILLMSGATLTMG---------
Mvan_4266|M.vanbaalenii_PYR-1 FFMRPLGGFFFG--PLGDRIGRQRVLALVILLMSASTLAIG---------
MAB_2263c|M.abscessus_ATCC_199 FLLRPLGGMVWG--PLGDRLGRKSVMAITIVLMALSTTLIG---------
MSMEG_6775|M.smegmatis_MC2_155 YLARPLGTVIFS--PMSDRIGRKKTFVVTLAVMGVATVAIG---------
MLBr_01562|M.leprae_Br4923 AYVLTFGGLMLLGGRLGDTIGRKRTFIVGVALFTISSVLCAVAWDEVTLV
.:* . :.* :**: : : : :: .
Mb1232|M.bovis_AF2122/97 LVPTTVAIGAAAPLILTTMRLLQGFAVG-GEWAGSALLSAEYAPASKRGW
Rv1200|M.tuberculosis_H37Rv LVPTTVAIGAAAPLILTTMRLLQGFAVG-GEWAGSALLSAEYAPASKRGW
MMAR_4238|M.marinum_M VVPSTATIGVSAPLILVALRLLQGFAVG-GEWAGSALLSIESAPAHKRGY
MUL_0949|M.ulcerans_Agy99 VVPSTATIGVSAPLILVALRLLQGFAVG-GEWAGSALLSIESAPAHKRGY
Mflv_2383|M.gilvum_PYR-GCK VLPTYAQIGLAAPILLTVLRLAQGFAVG-GEWGGATLMAVEHATADRRGF
MAV_4627|M.avium_104 VLPTAAQIGAWAPVLLLVLRVLQGFALG-GEWGGAVLLAVEHSPGDRRGR
TH_3722|M.thermoresistible__bu LLPTYESIGVLAPLLLLLLRCLQGFSAG-GEYGGGAVYLAEFAPDRRRGL
Mvan_4266|M.vanbaalenii_PYR-1 LVPGYDSIGVLAPILLLLLRCLQGFSAG-GEYGSGACFLAEYAPDRHRGF
MAB_2263c|M.abscessus_ATCC_199 ILPSWATIGMAAPALLILLRVIQGFSTG-GEYGGAATFMAEFAPDKKRGK
MSMEG_6775|M.smegmatis_MC2_155 CLPTYAAIGVWAPAMLLFLRIVQGVGLG-GEYGSAVVYVTEHAPAERRGR
MLBr_01562|M.leprae_Br4923 IARLLQGIGSAIASPTGLALVATTFSKGSARNTATAVFAAMTAIGSVMGL
** . .. * .. . . : *
Mb1232|M.bovis_AF2122/97 YG------MFTVVGGGIALVLTSLTFLGVNYTIGESSPTFMQWGWRIPFL
Rv1200|M.tuberculosis_H37Rv YG------MFTVVGGGIALVLTSLTFLGVNYTIGESSPTFMQWGWRIPFL
MMAR_4238|M.marinum_M YG------MFTVLGGGVALVVSGLTFLGVNYTIGESSSAFLQWGWRVPFL
MUL_0949|M.ulcerans_Agy99 YG------MFTVLGGGVALVVSGLTFLGVNYTIGESSSALLQWGWRVPFL
Mflv_2383|M.gilvum_PYR-GCK YG------AFPQMGAPAQTAAAT-LAFYLAARLPDDQ--FLAWGWRIPFL
MAV_4627|M.avium_104 YG------AVPQVGLALGLALGTGIFAFLQIVLGPAR--FLSYGWRIGFL
TH_3722|M.thermoresistible__bu IV------TFMAWSGVLGFLLGSVTVTALQVALPDQV--MTDVGWRIPFL
Mvan_4266|M.vanbaalenii_PYR-1 VV------SFLVWSVVVGFLLGSVTVTALEATLSESA--MNSFGWRIPFL
MAB_2263c|M.abscessus_ATCC_199 YG------SFLEFGTLGGFAVGAAFVLVLDATLSDDA--MHTWGWRIPFL
MSMEG_6775|M.smegmatis_MC2_155 YT------SVLQSTATVGLLFALVLVSLLKVLLSDEA--FTSWGWRVPFL
MLBr_01562|M.leprae_Br4923 VVGGALTEVSWRLAFLVNVPIGLVMIYLARTALHETHKERMKLDAAGAIL
: . :*
Mb1232|M.bovis_AF2122/97 VSAALIAVALYVRFNIDETPVFAR--ERADEKTRLGPAETPIAQVLR---
Rv1200|M.tuberculosis_H37Rv VSAALIAVALYVRFNIDETPVFAR--ERADEKTRLGPAETPIAQVLR---
MMAR_4238|M.marinum_M LSALLIAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLC---
MUL_0949|M.ulcerans_Agy99 LSALLIAFALYVRLEINETPVFARAMAQADDQESTAAARAPLAAVLC---
Mflv_2383|M.gilvum_PYR-GCK VSAILIVIGLVVRLTVTESPHFAEL------QRRSEVTRTPIVAAFR---
MAV_4627|M.avium_104 LSVLLVAIGIVVRLRVEETPAFREL------QDLQAASTVPIRDILRE--
TH_3722|M.thermoresistible__bu LAGPLGLIGLYIRLRLDDTPAFTALSEQE------EVAQSPLREAVQ---
Mvan_4266|M.vanbaalenii_PYR-1 IAGALGAVGLYIRLRLGDTPEFEALRESG------EVSTTPLKEAVT---
MAB_2263c|M.abscessus_ATCC_199 VALPMGLIGWYLRSRLDDPPLFKEMQEQEP--EGRETAFERLRDLVR---
MSMEG_6775|M.smegmatis_MC2_155 VSAPIVLVATLIRLRMQETPVFTALQDSG------QLSKTPLLDTVR---
MLBr_01562|M.leprae_Br4923 ATLACTAAVFAFSMGPEKGWISLTTIGSGLVALVAAIAFAVVERTAENPV
: . . : :
Mb1232|M.bovis_AF2122/97 -----RQRREIVLAAGSAVCCFG---FVYLASTYLASYAQTRLGYSRGSI
Rv1200|M.tuberculosis_H37Rv -----RQRREIVLAAGSAVCCFG---FVYLASTYLASYAQTRLGYSRGSI
MMAR_4238|M.marinum_M -----RQRREIVLAAGAMLAAFG---CLYLASTFLPSYAQLHLGYSRNLV
MUL_0949|M.ulcerans_Agy99 -----RQRREIVLAAGAMLAAFG---CLYLASTFLPSYAQLHLGYSRNLV
Mflv_2383|M.gilvum_PYR-GCK -----RHWRQILLVAGAYLSQGI---FAYICVAYLVSYATTVAEIPRDWA
MAV_4627|M.avium_104 ----RRSRRNTVLGLLSRWAEGS---AFNTWGVFAISYATGALGLNRVSV
TH_3722|M.thermoresistible__bu -----TAWRSILQVIGLMIIFN---VAYYVVFAYMPTYLIKELGLSSSDA
Mvan_4266|M.vanbaalenii_PYR-1 -----TSWRPILQIIGLVVVHN---VGFYVVYTFLPSYFTRTLEFSKIDA
MAB_2263c|M.abscessus_ATCC_199 -----DYRRPMVVMMLLVIALN---ITNYTLLSYQPTYLKTRLGMSETQG
MSMEG_6775|M.smegmatis_MC2_155 -----TWSSWKSILLGTFGAQGGTSVTLYTSIIYMLYFLQHVLEVDQTHT
MLBr_01562|M.leprae_Br4923 VPFDLFRDRNRLVTFIAIFLAGG---VIFSLTVSIGLYIQDILGYSALRA
:
Mb1232|M.bovis_AF2122/97 LFDSVLGGLLCIVFTALSSALCDQLGRRRVLLAGWAVALPWSLLVMP---
Rv1200|M.tuberculosis_H37Rv LFDSVLGGLLCIVFTALSSALCDQLGRRRVLLAGWAVALPWSLLVMP---
MMAR_4238|M.marinum_M LLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVMP---
MUL_0949|M.ulcerans_Agy99 LLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPLVMP---
Mflv_2383|M.gilvum_PYR-GCK LLGVFLGAVVAVATYPLFGALSDRVGRKPLYLAGVIAMALAVVPTFA---
MAV_4627|M.avium_104 LIAVTIAALLMAVLLPVSGVLTDRFGARRVYLAGIACYGLAAFPAFA---
TH_3722|M.thermoresistible__bu FISSTIACVVALVLILPLAALSDRIGRKPLLVGGAIAFAVLAYPLFL---
Mvan_4266|M.vanbaalenii_PYR-1 FYSITVASLVGIVLIPPLGALSDRVGRKPLLLAGSIGFAVFAYPLFL---
MAB_2263c|M.abscessus_ATCC_199 QIVILIGEVAMMAFLPFCGALSDRVGRKPMWAFSLTGLLVLSLPMFW---
MSMEG_6775|M.smegmatis_MC2_155 NLCLAVAIVIAAPCYPMFGAWSDRVGRSRVMLTGIVLWMLAAYPAFAGIR
MLBr_01562|M.leprae_Br4923 GIGFIPFVIAMGIGLGVSSQLVSRFSPRVLTIGGGWLLMVAMLYGWAFMN
: . .:.. : .
Mb1232|M.bovis_AF2122/97 LIDSGSPSLFAVAVVGMYAIG-GFGFGPTASFIPELFATSYRYTGSALAA
Rv1200|M.tuberculosis_H37Rv LIDSGSPSLFAVAVVGMYAIG-GFGFGPTASFIPELFATSYRYTGSALAA
MMAR_4238|M.marinum_M LIGSGDTVGFTVALLGLYAVA-ASGFGPAASLIPELFATRYRYTGTALAL
MUL_0949|M.ulcerans_Agy99 LIGSGDTVGFTVALLGLYAVA-ASGFGPAASLIPELFATRYRYTGTALAL
Mflv_2383|M.gilvum_PYR-GCK LINTGRPVMFVLALVLIFGLAMAPAAGVTGALFSMAFDADVRYSGVSVGY
MAV_4627|M.avium_104 LFGTKKLLWFGLAMVIVFGVVHALFYGAQGTLYSALYPTNTRYTGLSFVY
TH_3722|M.thermoresistible__bu -LLNSGSTAAAMIAHAGLAAIESVVISVAVVTAVEQFTTRVRYSGMSVGY
Mvan_4266|M.vanbaalenii_PYR-1 -LLNTGSLAAAIAAHAALAAIEAVFVCASLAAGAELFATRVRSSGYSIGY
MAB_2263c|M.abscessus_ATCC_199 -LMGQG-FGWAIVGFAVLGLLYIPQLSTITATFPCMFPTQVRYAGFAISY
MSMEG_6775|M.smegmatis_MC2_155 TAVGSSSWVTVSALISVLAVLTAMVMAPLPAFITEQFPPQSRTTGFGFAQ
MLBr_01562|M.leprae_Br4923 RGVPYFPNLLAPIVVGGIGIGMAVVPLTLSAIAGVGFDRIGPVSAIALML
. : :. ..
Mb1232|M.bovis_AF2122/97 N-----LAGVAGGALPPVIAGALVATYGS--WAIGVMLAILALISLVCTY
Rv1200|M.tuberculosis_H37Rv N-----LAGVAGGALPPVIAGALVATYGS--WAIGVMLAILALISLVCTY
MMAR_4238|M.marinum_M N-----VAGIVGGAAPPLIAGTLLASYGS--SAVGLMMTALVAASLLCTY
MUL_0949|M.ulcerans_Agy99 N-----VAGIVGGAAPPLIAGTLLASYGS--SAVGLMMTALVAASLLCTY
Mflv_2383|M.gilvum_PYR-GCK T-----LSQVLGSAFAPTIATALYAATGSSNSIAA-YLIAASAVSAVAVC
MAV_4627|M.avium_104 Q-----FSGVYASGVTPMILTALIAALGGAPWLACGYLVATAVISVLATA
TH_3722|M.thermoresistible__bu N-----VCVALFGGTTPYVMTWLIDTTAN-PLAPACAVTLAAVVSLGVVM
Mvan_4266|M.vanbaalenii_PYR-1 N-----VSVAIFGGTAPYVATWLVSRTGN-DIAPAFYVIAAAVVTFLTVL
MAB_2263c|M.abscessus_ATCC_199 N-----LSTAAFGGTAPLVNDLVVARTGW-DLFPAAYLMVACVVGLCALP
MSMEG_6775|M.smegmatis_MC2_155 Q-----LGNILFGGFLPLISLSLVDATGN-QLAGVGYSIVSLVPCLAVTL
MLBr_01562|M.leprae_Br4923 QSLGGPLVLAVIQAVITSRTLYLGGTTGPVKFMNDAQLRALDHGYTYGLL
. . . : .
Mb1232|M.bovis_AF2122/97 RLPETAG------SALVSR-------------------
Rv1200|M.tuberculosis_H37Rv RLPETAG------SALVSR-------------------
MMAR_4238|M.marinum_M LLPETAG------APLTAA-------------------
MUL_0949|M.ulcerans_Agy99 LLPETAG------APLTAA-------------------
Mflv_2383|M.gilvum_PYR-GCK FMPGGWRAAPAEARPEHTPTAPTG--------------
MAV_4627|M.avium_104 LIRD---------RDLYL--------------------
TH_3722|M.thermoresistible__bu TLRETAA------RPLAGTP------------------
Mvan_4266|M.vanbaalenii_PYR-1 TMRETAR------QPLRKLVSD----------------
MAB_2263c|M.abscessus_ATCC_199 FLIETAG------ASIAGTEIPCNEAAVPTDTVRA---
MSMEG_6775|M.smegmatis_MC2_155 FWGLRSE------RSRRHDISAASALSVRREPQTL---
MLBr_01562|M.leprae_Br4923 WVAGAVVIVGVAALFIGYTPEQVAYAQEVKEAVDAGEL