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GPGGRTRVSPRRVAIASFVGTTVEFYDFLIYGTAAALVFPKLFFPNASPAAGILLSFATFGVGFIARPLG GIVFGHFGDRVGRRRMLVYSLVGMGVSTVLIGVLPTYAQIGLAAPILLTVLRLAQGFAVGGEWGGATLMA VEHATADRRGFYGAFPQMGAPAQTAAATLAFYLAARLPDDQFLAWGWRIPFLVSAILIVIGLVVRLTVTE SPHFAELQRRSEVTRTPIVAAFRRHWRQILLVAGAYLSQGIFAYICVAYLVSYATTVAEIPRDWALLGVF LGAVVAVATYPLFGALSDRVGRKPLYLAGVIAMALAVVPTFALINTGRPVMFVLALVLIFGLAMAPAAGV TGALFSMAFDADVRYSGVSVGYTLSQVLGSAFAPTIATALYAATGSSNSIAAYLIAASAVSAVAVCFMPG GWRAAPAEARPEHTPTAPTG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2383 | - | - | 100% (441) | major facilitator transporter |
| M. gilvum PYR-GCK | Mflv_0140 | - | 1e-91 | 43.90% (426) | major facilitator transporter |
| M. gilvum PYR-GCK | Mflv_4524 | - | 1e-89 | 40.88% (411) | major facilitator transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1232 | - | 3e-82 | 41.84% (423) | integral membrane transport protein |
| M. tuberculosis H37Rv | Rv1200 | - | 3e-82 | 41.84% (423) | integral membrane transport protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2481 | - | 9e-93 | 44.02% (418) | putative integral membrane transporter |
| M. marinum M | MMAR_4238 | - | 2e-79 | 40.82% (414) | integral membrane transport protein |
| M. avium 104 | MAV_4627 | - | 3e-95 | 46.12% (412) | major facilitator superfamily protein |
| M. smegmatis MC2 155 | MSMEG_4886 | - | 0.0 | 79.67% (423) | major facilitator family protein transporter |
| M. thermoresistible (build 8) | TH_3714 | - | 0.0 | 76.96% (434) | PUTATIVE major facilitator superfamily MFS_1 |
| M. ulcerans Agy99 | MUL_0949 | - | 7e-79 | 40.58% (414) | integral membrane transport protein |
| M. vanbaalenii PYR-1 | Mvan_2899 | - | 7e-93 | 43.24% (407) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4886|M.smegmatis_MC2_155 -------------------MATSTGVRVSPLRVAVASFIGTTVEFYDFLI
TH_3714|M.thermoresistible__bu ----------------MSAEAATPTSRVTPRRVAVASFIGTTVEFYDFLI
Mflv_2383|M.gilvum_PYR-GCK -------------------MGPGGRTRVSPRRVAIASFVGTTVEFYDFLI
MAV_4627|M.avium_104 MAATLPAPAPAGLADGHPLDESAEQQRRRLRIVVAASLLGTTVEWYDFFL
MAB_2481|M.abscessus_ATCC_1997 MTTTSAVP-------AVHAGGPADGDAPAARTVALSCMVGTTIEWYDFYL
Mvan_2899|M.vanbaalenii_PYR-1 ------------------MNEASVADSALLRRVALSSLLGTAIEYYDFLV
Mb1232|M.bovis_AF2122/97 -----------------------------MKRVALACLVGSAIEFYDFLI
Rv1200|M.tuberculosis_H37Rv -----------------------------MKRVALACLVGSAIEFYDFLI
MMAR_4238|M.marinum_M -----------------------------MSRVALACVVGSTVEYYDFCI
MUL_0949|M.ulcerans_Agy99 -----------------------------MSRVALACVVGSTVEYYDFCI
*. :..:*:::*:*** :
MSMEG_4886|M.smegmatis_MC2_155 YGTAAALVFPKLFFPQASPAAGILLSFATFGVGFIARPLGGIVFGHFGDR
TH_3714|M.thermoresistible__bu YGTAAALVFPKLFFPTASPASGVLLSFATFGVGFFARPLGGIVFGHFGDR
Mflv_2383|M.gilvum_PYR-GCK YGTAAALVFPKLFFPNASPAAGILLSFATFGVGFIARPLGGIVFGHFGDR
MAV_4627|M.avium_104 YATAAGLVFNKVFFPNESSLVGTLLAFATFAVGFVMRPIGGLVFGHIGDR
MAB_2481|M.abscessus_ATCC_1997 YATAAALVLKPLFFPSVSPTAGTLASFATYAAGFGARPVGAVIAGHLGDR
Mvan_2899|M.vanbaalenii_PYR-1 YGTMSALVFGLVFFPDSDPAVATIAAFGTLAAGYVARPVGGIVFGHFGDR
Mb1232|M.bovis_AF2122/97 YGTAAALVFPTVFFPHLDPTVAAVASMGTFAVAFLSRPFGAAVFGYFGDR
Rv1200|M.tuberculosis_H37Rv YGTAAALVFPTVFFPHLDPTVAAVASMGTFAVAFLSRPFGAAVFGYFGDR
MMAR_4238|M.marinum_M YGTAAALVFPAVFYPGLSPALATIASMGTFATAFLSRPLGAAVFGHFGDR
MUL_0949|M.ulcerans_Agy99 YGTAAALVFPAVFYPGLSPALATIASMGTFATAFLSRPLGAAVFGHFGDR
*.* :.**: :*:* .. . : ::.* ...: **.*. : *::***
MSMEG_4886|M.smegmatis_MC2_155 IGRKRMLVYSLVGMGVSTVLIGLLPSYAQIGLAAPVLLTVLRLCQGFAVG
TH_3714|M.thermoresistible__bu LGRKRMLVYSLVGMGVATVLIGLLPTYAQIGMAAPALLTLLRLAQGFAMG
Mflv_2383|M.gilvum_PYR-GCK VGRRRMLVYSLVGMGVSTVLIGVLPTYAQIGLAAPILLTVLRLAQGFAVG
MAV_4627|M.avium_104 IGRKRSLALTMLIMGGATALIGVLPTAAQIGAWAPVLLLVLRVLQGFALG
MAB_2481|M.abscessus_ATCC_1997 VGRKAVLVGALLLMGVATAVIGALPTYSEAGVLAPAALATLRVLQGLAAG
Mvan_2899|M.vanbaalenii_PYR-1 IGRKSMLVLTMTLMGTASFLIGLLPSFAAVGVAAPILLVALRVIQGVAIG
Mb1232|M.bovis_AF2122/97 LGRKKTLVATLLIMGLATVTVGLVPTTVAIGAAAPLILTTMRLLQGFAVG
Rv1200|M.tuberculosis_H37Rv LGRKKTLVATLLIMGLATVTVGLVPTTVAIGAAAPLILTTMRLLQGFAVG
MMAR_4238|M.marinum_M LGRKKTLVATLLIMALSTVTVGVVPSTATIGVSAPLILVALRLLQGFAVG
MUL_0949|M.ulcerans_Agy99 LGRKKTLVATLLIMALSTVTVGVVPSTATIGVSAPLILVALRLLQGFAVG
:**: *. :: *. :: :* :*: * ** * :*: **.* *
MSMEG_4886|M.smegmatis_MC2_155 GEWGGATLMAVEHASADRRGFYGAFPQMGAPAGTASAT-LAFFLASQLPD
TH_3714|M.thermoresistible__bu GEWGGATLMAVEHASADRKGFYGAFPQMGAPAGTATAT-LAFFAVSRLPD
Mflv_2383|M.gilvum_PYR-GCK GEWGGATLMAVEHATADRRGFYGAFPQMGAPAQTAAAT-LAFYLAARLPD
MAV_4627|M.avium_104 GEWGGAVLLAVEHSPGDRRGRYGAVPQVGLALGLALGTGIFAFLQIVLGP
MAB_2481|M.abscessus_ATCC_1997 AEWGGAALLAVEHAPVGRRGLFGSFTQLGSPAGMLLATGVFGLTRALTGP
Mvan_2899|M.vanbaalenii_PYR-1 GEWGGATLMVTEHAEAHRRGFWNGVMQMGSPIGSLLSVAVVTVIT-LLPD
Mb1232|M.bovis_AF2122/97 GEWAGSALLSAEYAPASKRGWYGMFTVVGGGIALVLTSLTFLGVNYTIGE
Rv1200|M.tuberculosis_H37Rv GEWAGSALLSAEYAPASKRGWYGMFTVVGGGIALVLTSLTFLGVNYTIGE
MMAR_4238|M.marinum_M GEWAGSALLSIESAPAHKRGYYGMFTVLGGGVALVVSGLTFLGVNYTIGE
MUL_0949|M.ulcerans_Agy99 GEWAGSALLSIESAPAHKRGYYGMFTVLGGGVALVVSGLTFLGVNYTIGE
.**.*:.*: * : ::* :. . :*
MSMEG_4886|M.smegmatis_MC2_155 AQ--FLAWGWRLPFLFSAALIVIGLVIRLKLTESPEFAAVVQNSA-----
TH_3714|M.thermoresistible__bu GQ--FLSWGWRLPFLLSAVLIGIGLAVRLTLTESPDFAAVQARSA-----
Mflv_2383|M.gilvum_PYR-GCK DQ--FLAWGWRIPFLVSAILIVIGLVVRLTVTESPHFAELQRRSE-----
MAV_4627|M.avium_104 AR--FLSYGWRIGFLLSVLLVAIGIVVRLRVEETPAFRELQDLQA-----
MAB_2481|M.abscessus_ATCC_1997 EA--FLAFGWRIPFLSSIVLVVVGLAIRLRLRDSVVFRKVLERGE-----
Mvan_2899|M.vanbaalenii_PYR-1 ES--FLSWGWRIPFLVSLLLLAVGIYVRLSVTESPVFEAARKEAAGN---
Mb1232|M.bovis_AF2122/97 SSPTFMQWGWRIPFLVSAALIAVALYVRFNIDETPVFAR--ERADEKTRL
Rv1200|M.tuberculosis_H37Rv SSPTFMQWGWRIPFLVSAALIAVALYVRFNIDETPVFAR--ERADEKTRL
MMAR_4238|M.marinum_M SSSAFLQWGWRVPFLLSALLIAFALYVRLEINETPVFARAMAQADDQEST
MUL_0949|M.ulcerans_Agy99 SSSALLQWGWRVPFLLSALLIAFALYVRLEINETPVFARAMAQADDQEST
:: :***: ** * *: ..: :*: : :: *
MSMEG_4886|M.smegmatis_MC2_155 -VRRMPIVEAFR--RHWRQIVLVAGAYLSQGVFAYICVAYLVSYATTAAG
TH_3714|M.thermoresistible__bu -VHRMPIAEAFR--RHRRQILLVAGAYLSQGVFAYICVAYLVSYGTSVAG
Mflv_2383|M.gilvum_PYR-GCK -VTRTPIVAAFR--RHWRQILLVAGAYLSQGIFAYICVAYLVSYATTVAE
MAV_4627|M.avium_104 -ASTVPIRDILRERRSRRNTVLGLLSRWAEGSAFNTWGVFAISYATGALG
MAB_2481|M.abscessus_ATCC_1997 -AARLPVVEVLR--TQSRNVLLTTGLRLSQIALFVLLTTFSLTYLQGSFG
Mvan_2899|M.vanbaalenii_PYR-1 -APRVPFVEILR---RPRTLVLACAVGIGPFALTALISTYMISYAT-AIG
Mb1232|M.bovis_AF2122/97 GPAETPIAQVLR--RQRREIVLAAGSAVCCFGFVYLASTYLASYAQTRLG
Rv1200|M.tuberculosis_H37Rv GPAETPIAQVLR--RQRREIVLAAGSAVCCFGFVYLASTYLASYAQTRLG
MMAR_4238|M.marinum_M AAARAPLAAVLC--RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLG
MUL_0949|M.ulcerans_Agy99 AAARAPLAAVLC--RQRREIVLAAGAMLAAFGCLYLASTFLPSYAQLHLG
*. : * :* .: :*
MSMEG_4886|M.smegmatis_MC2_155 IDRTAALFGVFVAALVAVAAYPAFGAWSDVVGRKRLFLVGVALMAASVFP
TH_3714|M.thermoresistible__bu IDRTATLFGVSVAAVLAVVMYPLFGSLSDTFGRKPLFLAGVIAMGVSIGP
Mflv_2383|M.gilvum_PYR-GCK IPRDWALLGVFLGAVVAVATYPLFGALSDRVGRKPLYLAGVIAMALAVVP
MAV_4627|M.avium_104 LNRVSVLIAVTIAALLMAVLLPVSGVLTDRFGARRVYLAGIACYGLAAFP
MAB_2481|M.abscessus_ATCC_1997 GDSQIGLTAVLISSALGILSTPVWSALSDRVGRRPLYLFGSAAGPLALGL
Mvan_2899|M.vanbaalenii_PYR-1 YHRTDVMTALIFTSLTGLIAIPFFSALSDHVGRRLVMVAGAIGIIGYAWP
Mb1232|M.bovis_AF2122/97 YSRGSILFDSVLGGLLCIVFTALSSALCDQLGRRRVLLAGWAVALPWSLL
Rv1200|M.tuberculosis_H37Rv YSRGSILFDSVLGGLLCIVFTALSSALCDQLGRRRVLLAGWAVALPWSLL
MMAR_4238|M.marinum_M YSRNLVLLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPL
MUL_0949|M.ulcerans_Agy99 YSRNLVLLIGVLGGLVCIGFVALSAILCDRFGRRRVMLVGWAVGLFWSPL
: . . . . * .* : : : *
MSMEG_4886|M.smegmatis_MC2_155 VFALIDTGSALLFGVALVLVFGLAMAPAAGVTGALFSLAFDADVRYSGVS
TH_3714|M.thermoresistible__bu AFALIDTGRPALFLVALVLVFGLAMAPAAGVTGALFAMTFDADVRYSGVS
Mflv_2383|M.gilvum_PYR-GCK TFALINTGRPVMFVLALVLIFGLAMAPAAGVTGALFSMAFDADVRYSGVS
MAV_4627|M.avium_104 AFALFGTKKLLWFGLAMVIVFGVVHALFYGAQGTLYSALYPTNTRYTGLS
MAB_2481|M.abscessus_ATCC_1997 FFLAAGSGSKVLVVLSIVFGINVVHDAMYGPQAAWFAELFDTRVRYSGAS
Mvan_2899|M.vanbaalenii_PYR-1 FYALVDMRSQAYLTAAMVIAQ-LIQSMMYAPLGALFSEMFGTTVRYTGAS
Mb1232|M.bovis_AF2122/97 VMPLIDSGSPSLFAVAVVGMY-AIGGFGFGPTASFIPELFATSYRYTGSA
Rv1200|M.tuberculosis_H37Rv VMPLIDSGSPSLFAVAVVGMY-AIGGFGFGPTASFIPELFATSYRYTGSA
MMAR_4238|M.marinum_M VMPLIGSGDTVGFTVALLGLY-AVAASGFGPAASLIPELFATRYRYTGTA
MUL_0949|M.ulcerans_Agy99 VMPLIGSGDTVGFTVALLGLY-AVAASGFGPAASLIPELFATRYRYTGTA
. . ::: . .: . : : **:* :
MSMEG_4886|M.smegmatis_MC2_155 IGYTLSQVLGSAFAPTIAAALYAAAQSSDSIAW-YLVAVSAISVVAGTLL
TH_3714|M.thermoresistible__bu IGYTLSQVLGSAFAPTIAAALYAATESSGSIVA-YLIGVSVISAVSVCLL
Mflv_2383|M.gilvum_PYR-GCK VGYTLSQVLGSAFAPTIATALYAATGSSNSIAA-YLIAASAVSAVAVCFM
MAV_4627|M.avium_104 FVYQFSGVYASGVTPMILTALIAALGGAPWLACGYLVATAVISVLATALI
MAB_2481|M.abscessus_ATCC_1997 LGYQIGAVLSGGFAPLIAAALLAANHGDPRLIVCYYLALSVLTFGAACVA
Mvan_2899|M.vanbaalenii_PYR-1 MGYQLAALLGAGFTPLIASALHAQEVSRTPLVA-LAAGCGLVTVVAVWRI
Mb1232|M.bovis_AF2122/97 LAANLAGVAGGALPPVIAGALVATYGS--WAIGVMLAILALISLVCTYRL
Rv1200|M.tuberculosis_H37Rv LAANLAGVAGGALPPVIAGALVATYGS--WAIGVMLAILALISLVCTYRL
MMAR_4238|M.marinum_M LALNVAGIVGGAAPPLIAGTLLASYGS--SAVGLMMTALVAASLLCTYLL
MUL_0949|M.ulcerans_Agy99 LALNVAGIVGGAAPPLIAGTLLASYGS--SAVGLMMTALVAASLLCTYLL
. .. : ... .* * :* * . : .
MSMEG_4886|M.smegmatis_MC2_155 PS------DRSAPEA-----AVVKG--
TH_3714|M.thermoresistible__bu PGGWGRTGDQPATEVPASVRPMVSGPD
Mflv_2383|M.gilvum_PYR-GCK PGGWR---AAPAEARPEHTPTAPTG--
MAV_4627|M.avium_104 RD-------RDLYL-------------
MAB_2481|M.abscessus_ATCC_1997 RETYR---DQIGDSL------------
Mvan_2899|M.vanbaalenii_PYR-1 SETRG----TDLTTV------------
Mb1232|M.bovis_AF2122/97 PETAG----SALVSR------------
Rv1200|M.tuberculosis_H37Rv PETAG----SALVSR------------
MMAR_4238|M.marinum_M PETAG----APLTAA------------
MUL_0949|M.ulcerans_Agy99 PETAG----APLTAA------------