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MRGLRVLDFTHVVAGPLCTMTLADLGADVVKIEPPAGEIGRRIGPPWRDGQSVIWQSVNRNKRSLTLDLK TPAGRRAARRMARQADVVVESFRPGVMTDLDLGYDTLASANPALVYCSISAFGQAGPASDRPGVDGIMQA VTGLMSTLGEPESGPAKVQVPAADMVTGYLASIAVLAALHEVRDGGRGQHLDVSLYNATILLQQIGFTSY LASGAEPQRLGSAAPYAAPNEALPTADGWIMIAAYDPARWNALCDALGAPDLSSDARFATNDDRVRNRPA LRTELGRLLRARTTQVWLDVLSARDILCAPVNGYGQVVASPEYAASGLHRPIGPIDTPGLVLGPSQPAAP PDTAPPAPGQHSAEVLAEYGLSEDEVAALIEHGVVNDVAPSRAAS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6773 | - | - | 100% (395) | CaiB/BaiF family protein |
| M. smegmatis MC2 155 | MSMEG_4120 | - | 3e-59 | 36.13% (393) | CAIB/BAIF family protein |
| M. smegmatis MC2 155 | MSMEG_6689 | - | 3e-58 | 37.85% (362) | CAIB/BAIF family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 4e-60 | 37.01% (381) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_4465 | - | 8e-52 | 31.55% (393) | Formyl-CoA transferase |
| M. tuberculosis H37Rv | Rv3272 | - | 1e-59 | 36.75% (381) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0824 | - | 6e-61 | 42.95% (312) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_1267 | - | 9e-57 | 35.73% (389) | acyl-CoA transferase |
| M. avium 104 | MAV_4237 | - | 2e-58 | 35.16% (384) | YfdE protein |
| M. thermoresistible (build 8) | TH_3339 | - | 6e-60 | 34.44% (392) | PUTATIVE putative L-carnitine dehydratase/bile acid-inducible |
| M. ulcerans Agy99 | MUL_2621 | - | 5e-57 | 35.73% (389) | acyl-CoA transferase |
| M. vanbaalenii PYR-1 | Mvan_1855 | - | 1e-58 | 39.50% (319) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1267|M.marinum_M -------MPEGNPAKPLDGFRVLDFTQNVAGPLAGQVLADLGAEVIKVEA
MUL_2621|M.ulcerans_Agy99 -------MPEGNPAKPLDGFRVLDFTQNVAGPLAGQVLADLGAEVIKVEA
MAV_4237|M.avium_104 ---MPHETPNGKPPKPLDGFRVLDFTQNIAGPMAGQVLADLGAEVIKIEA
Mb3300|M.bovis_AF2122/97 -------MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEA
Rv3272|M.tuberculosis_H37Rv -------MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEA
MSMEG_6773|M.smegmatis_MC2_155 ----------------MRGLRVLDFTHVVAGPLCTMTLADLGADVVKIEP
Mflv_4465|M.gilvum_PYR-GCK -----------MTTGPLDGIRVIEVGTLISGPFAGRLLGDMGAEVIKVEP
TH_3339|M.thermoresistible__bu MTTEVETTATQPTTGPLHGIRVVEMGSLLAGPIVGQMMGDLGADVVKIED
MAB_0824|M.abscessus_ATCC_1997 -----------MTAAALDGLLVVDFSRVLAGPYATMMLGDFGAEVIKIER
Mvan_1855|M.vanbaalenii_PYR-1 -----------MTG-ALDGVVVVDFSRVLAGPYATMMLGDFGAEVIKVER
: *. *::. ::** : *:**:*:*:*
MMAR_1267|M.marinum_M PGGEAARHITAVLPHRPPLATYFLPNNRGKKSVSVDLSTDTARRQILRLA
MUL_2621|M.ulcerans_Agy99 PGGEAARHITAVLPHRPPLATYFLPNNRGKKSVSVDLSTDTARRQILRLA
MAV_4237|M.avium_104 PIGEAARHITAVLPGRPPLATLFLPHNRGKKSVLADLRDDEAKQRILRLV
Mb3300|M.bovis_AF2122/97 PGGEAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLA
Rv3272|M.tuberculosis_H37Rv PGGEAARQITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLA
MSMEG_6773|M.smegmatis_MC2_155 PAGEIGRRIG--PPWRDGQSVIWQSVNRNKRSLTLDLKTPAGRRAARRMA
Mflv_4465|M.gilvum_PYR-GCK PGAPDPLRTWGQ-AELDGHHFFWTVHARNKKAVTLNLRVPEGRDLFLDLV
TH_3339|M.thermoresistible__bu PGKGDPLRQWGQ-NRPKGQSLWFSIVGRNKRSVTINLREPRGQELVRQLV
MAB_0824|M.abscessus_ATCC_1997 PVLGDDTRQWGPPYDSDGQATYFNSVNRNKQSVVLDLTSPDGQHRARELA
Mvan_1855|M.vanbaalenii_PYR-1 PGVGDDTRQWGPPYDSSGVATYFNAVNRNKRSVVLDLSTPDGRQQARDLV
* : : *.*::: :* .: :.
MMAR_1267|M.marinum_M DTADVVLEGFRPGVMERMGLGPEDLRARNPKLIYARLSAFGGNGPHGTRP
MUL_2621|M.ulcerans_Agy99 DTADVVLEGFRPGVMERMGLGPEDLRARNPKLIYARLSAFGGNGPHGTRP
MAV_4237|M.avium_104 DTADVVLEGFRPGVMERMGLGPEELQGRNPRLVYARLSAYGGNGPEGSRP
Mb3300|M.bovis_AF2122/97 DTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRP
Rv3272|M.tuberculosis_H37Rv DTADVVLEAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRP
MSMEG_6773|M.smegmatis_MC2_155 RQADVVVESFRPGVMTDLDLGYDTLASANPALVYCSISAFGQAGPASDRP
Mflv_4465|M.gilvum_PYR-GCK ERSDVIVENFRPGTLEKWNLGYDVLRERNRGIILVRVSGYGQTGPDAHKA
TH_3339|M.thermoresistible__bu AEADVLVENFRPGTMERWGLGYSDLAEINPRLVIVRVSGFGQDGPYASRP
MAB_0824|M.abscessus_ATCC_1997 GRADVVVENFRAGTMEKFGLGYQSLKQLNPGLIYCAITGFGR-GAGADLP
Mvan_1855|M.vanbaalenii_PYR-1 AGADIVVENFRPGTMERLGLGYEDLRAVRPDVIYCSITGFGR-GGGAALP
:*:::* **.*.: .** . * . :: ::.:* * . .
MMAR_1267|M.marinum_M GVDLMVAAEAGMTTGMPTPDGKPQIIPFQLVDNASGHVLAQAVLAALLNR
MUL_2621|M.ulcerans_Agy99 GVDLMVAAEAGMTTGMPTPDGKPQIIPFQLVDNASGHVLAQAVLAALLNR
MAV_4237|M.avium_104 GVDLMVAAESGMTTGMPTPTGKPQIIPFQLVDAASGHVLAQAVLAALLNR
Mb3300|M.bovis_AF2122/97 GIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHR
Rv3272|M.tuberculosis_H37Rv GIDLVVAAEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHR
MSMEG_6773|M.smegmatis_MC2_155 GVDGIMQAVTGLMSTLGEPESGPAKVQVPAADMVTGYLASIAVLAALHEV
Mflv_4465|M.gilvum_PYR-GCK GYASVAEAASGLRHMNGFPGGPPPRLALSLGDSLAGMFAAQGALAALYRR
TH_3339|M.thermoresistible__bu GYGAIGEAMGGLRYVVGDPSTPPSRVGISIGDTLAALFATIGALAALRER
MAB_0824|M.abscessus_ATCC_1997 GYDLLVQAVGGLMSVTGPDAAHPSKVGVALVDVLTALHALSGILAALSYR
Mvan_1855|M.vanbaalenii_PYR-1 GYDLLVQAVGGLMSVTGTEPGDPTKAGVALVDVLAGLHALSGILAALHHR
* : * *: * . * :. . ****
MMAR_1267|M.marinum_M ERHGVADTVRVAMYDVAVGLQANQLTMHLNRPSSDAPKRPEQTPAGARRK
MUL_2621|M.ulcerans_Agy99 ERHGVADTVRVAMYDVAVGLQANQLTMHLNRPSSDAPKRPEQTPAGARRK
MAV_4237|M.avium_104 ERHGVADVVRVAMYDVAVSLQASQLTIHLNKPNADH-KPSDSASKPKRRK
Mb3300|M.bovis_AF2122/97 ERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQ-PKPEPAPKAKRRK
Rv3272|M.tuberculosis_H37Rv ERNGVADVVQVAMYDVAVGLQANQLMMHLNRAASDQ-PKPEPAPKAKRRK
MSMEG_6773|M.smegmatis_MC2_155 RDGGRGQHLDVSLYNATILLQQIGFTSYLASG-----------AEPQRLG
Mflv_4465|M.gilvum_PYR-GCK SVTGEGQIVDAALTESCLAVQESTIPDYDVGG-----------VVRGPSG
TH_3339|M.thermoresistible__bu EISGRGQMVDSAIYEAVLGVMESLVPEWTVSG-----------YQRERTG
MAB_0824|M.abscessus_ATCC_1997 DRTGQGQRVDTDLMSVLLSSLVNQASGYLGAG-----------VVPEALG
Mvan_1855|M.vanbaalenii_PYR-1 GRTGEGQRVDTDLLSVLLSSMVNQASGFLGAG-----------VVPAMMG
* .: : : . :
MMAR_1267|M.marinum_M RVAFATQPSDAFRAADG-YLLISAYVPKHWQRLCEIIGRPDLLDDERFID
MUL_2621|M.ulcerans_Agy99 RVAFATQPSDAFRAADG-YLLISAYVPKHWQRLCEIIGQPDLLDDERFID
MAV_4237|M.avium_104 GVGFATQPSDAFKAADG-YLVISAYVPKHWDKLCEVIGRPDLRDDERFAD
Mb3300|M.bovis_AF2122/97 GVGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIGRPDLVEDQRFAE
Rv3272|M.tuberculosis_H37Rv GVGFATQPSDAFRTADG-YIVISAYVPKHWQKLCYLIGRPDLVEDQRFAE
MSMEG_6773|M.smegmatis_MC2_155 SAAPYAAPNEALPTADG-WIMIAAYDPARWNALCDALGAPDLSSDARFAT
Mflv_4465|M.gilvum_PYR-GCK TRLEGIAPSNIYPTADGSWVVIAANQDTVFRRLCAAMGQPELATDERFAD
TH_3339|M.thermoresistible__bu AILPKIAPSNVYPTSDDTWILIAANQDTVFRRLAEAMGRPELAEDERYAT
MAB_0824|M.abscessus_ATCC_1997 NRHPSIAPYQTFETADR-PIAIAVGNDKQFRLLVQALEMPRLARDDRFAT
Mvan_1855|M.vanbaalenii_PYR-1 NRHPSIAPYQTFDTADR-PIAVAVGNDKQFRAFSTAIGQPELADDPRFVT
* : ::* : ::. : : : * * * *:
MMAR_1267|M.marinum_M QRARAINYAELTEELESALAAKTAAQWVELLHEGGLMACLAYTWKQVVTT
MUL_2621|M.ulcerans_Agy99 QRARAINYAELTEELESALAAKTAAQWVELLHEGGLMACLAYTWKQVVTT
MAV_4237|M.avium_104 QRSRALNYPELTEELEKALAAKTADEWVRLLQAAGLMACHAYTWKQVVGT
Mb3300|M.bovis_AF2122/97 QRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDT
Rv3272|M.tuberculosis_H37Rv QRSRSINYAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDT
MSMEG_6773|M.smegmatis_MC2_155 NDDRVRNRPALRTELGRLLRARTTQVWLDVLSARDILCAPVNGYGQVVAS
Mflv_4465|M.gilvum_PYR-GCK HVARGRNQDEIDKIIGGWAAQRQPDEIISTLSEAGVISGPINTVAEVVED
TH_3339|M.thermoresistible__bu HVARGEHQAELDEIVAEFTRRHTAAEVEALMHKHNVPVGKIYRPKEMLAD
MAB_0824|M.abscessus_ATCC_1997 NPLRVRHRGELVRVLEQRLREKNADDWYDTLTAVGVPAGPINDIAEAFR-
Mvan_1855|M.vanbaalenii_PYR-1 NPARVANRDALCALIVPALKAHGADHWYAKLTTVGVPAGPINDLSEAFA-
: * : : : : . : .: : .
MMAR_1267|M.marinum_M PLFAENELALQVG-------------SGDDAVTVIRTPARYSSFSAVLA-
MUL_2621|M.ulcerans_Agy99 PLFAENELALQVD-------------SGDDAVTVIRTPARYSSFSAVLA-
MAV_4237|M.avium_104 PLFAENELALQVG-------------EGADAVTVIRTPARYSSFEAASAG
Mb3300|M.bovis_AF2122/97 PLFAESDLTLEVG-------------RGADTITVIRTPARYASFRAVVT-
Rv3272|M.tuberculosis_H37Rv PLFAENDLTLEVG-------------RGADTITVIRTPARYASFRAVVT-
MSMEG_6773|M.smegmatis_MC2_155 PEYAASGLHRPIGPIDTPGLVLGPSQPAAPPDTAPPAPGQHSAEVLAEYG
Mflv_4465|M.gilvum_PYR-GCK PQLQARGMIADHWDERIGR----NVKGPGVVPVLSETPGTIRSAGSARPG
TH_3339|M.thermoresistible__bu PQFRARESITSVDHPVLG-----EIQMQNVFPRLSRTRGSIRWPGPG-LG
MAB_0824|M.abscessus_ATCC_1997 ---FAERLGLDVAVTVPGS----PEPQVANPISMSKTPVVYRNGPPR---
Mvan_1855|M.vanbaalenii_PYR-1 ---FARGLGIDAAVQVPGS----PAPQVANPVTMSATPVSYRSGPPA---
:
MMAR_1267|M.marinum_M ---EPPAATGEHNETLLGES-------
MUL_2621|M.ulcerans_Agy99 ---DPPPATGEHNETLLGES-------
MAV_4237|M.avium_104 WATDPPPALGQHTEEYLGAPQTAS---
Mb3300|M.bovis_AF2122/97 ---DPPPTAGEHNAVFLARP-------
Rv3272|M.tuberculosis_H37Rv ---DPPPTAGEHNAVFLARP-------
MSMEG_6773|M.smegmatis_MC2_155 LSEDEVAALIEHGVVNDVAPSRAAS--
Mflv_4465|M.gilvum_PYR-GCK QHNDEIYRDLLGRSAAELDKLQEEGVL
TH_3339|M.thermoresistible__bu EHTDEVLR-QLGLSDEELQKLHDAGVV
MAB_0824|M.abscessus_ATCC_1997 ----------LGQSRA-----------
Mvan_1855|M.vanbaalenii_PYR-1 ----------LGDSPIAEKP-------