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TNTTDNGPLHDLTVVDMTTSYAGPTAAMYLADLGARVIKIERPGSGDDTRGWGPPFVDGDSAWFASANRN KRSLVLDLRSGTGRDVLLRLIDSADAFLQSMNPAKLVRMGIDAENLHRRNPRLVYCAMSGFGLDGPDSNL PGYDLVAQARSGLMSVTGEKGRSPQRVSTALSDIATGMCAALAVSAALVQQAKTGKGATIDVSLLDTDLA LMAPRIAAYHAGDPEPGPSGGTDSVLAVYQSFEASDRSIVVAIGNDAMWLRFCAAIDLPDLASDPDLADN AGRRAQRPRITALIAERISTRTAAEWVRILNDVDVPVSLVQTLSEVVKDPQVVARGSLMPVPGSTERLAT VHSPFRFDGLAVRNKRFPDLGADSRRVLAELGYGPDDIAALFAAGVVSEPAGAGEVVS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4120 | - | - | 100% (409) | CAIB/BAIF family protein |
| M. smegmatis MC2 155 | MSMEG_2171 | - | 1e-67 | 38.64% (383) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. smegmatis MC2 155 | MSMEG_6689 | - | 1e-61 | 37.90% (343) | CAIB/BAIF family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3300 | - | 8e-44 | 29.78% (366) | hypothetical protein Mb3300 |
| M. gilvum PYR-GCK | Mflv_4465 | - | 2e-53 | 34.53% (333) | Formyl-CoA transferase |
| M. tuberculosis H37Rv | Rv3272 | - | 6e-44 | 29.78% (366) | hypothetical protein Rv3272 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0824 | - | 3e-61 | 37.76% (339) | putative L-carnitine dehydratase |
| M. marinum M | MMAR_1494 | - | 7e-55 | 35.31% (337) | hypothetical protein MMAR_1494 |
| M. avium 104 | MAV_1892 | - | 3e-54 | 33.50% (394) | L-carnitine dehydratase/bile acid-inducible protein F |
| M. thermoresistible (build 8) | TH_3905 | - | 1e-55 | 35.71% (336) | PUTATIVE Formyl-CoA transferase |
| M. ulcerans Agy99 | MUL_2446 | - | 2e-54 | 35.01% (337) | hypothetical protein MUL_2446 |
| M. vanbaalenii PYR-1 | Mvan_1855 | - | 1e-63 | 39.23% (339) | L-carnitine dehydratase/bile acid-inducible protein F |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_4120|M.smegmatis_MC2_155 MTNTTDNGPLHDLTVVDMTTSYAGPTAAMYLADLGARVIKIERPGSGDDT
MAV_1892|M.avium_104 ------MGPLSGVTVVSLEQAVAAPYATRQLADLGARVIKVERPDGGDFA
MAB_0824|M.abscessus_ATCC_1997 ----MTAAALDGLLVVDFSRVLAGPYATMMLGDFGAEVIKIERPVLGDDT
Mvan_1855|M.vanbaalenii_PYR-1 ----MTG-ALDGVVVVDFSRVLAGPYATMMLGDFGAEVIKVERPGVGDDT
Mflv_4465|M.gilvum_PYR-GCK ----MTTGPLDGIRVIEVGTLISGPFAGRLLGDMGAEVIKVEPPGAPDPL
TH_3905|M.thermoresistible__bu ---VTVTGPLDGIRVLELGTLIAGPFAGRLLGDMGAEVIKIELPGAPDPL
MMAR_1494|M.marinum_M ---MTEPGALDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEAPGAPDPL
MUL_2446|M.ulcerans_Agy99 ---MTEPGALDGIRVLELGTLIAGPFAGRLLGDMGADVIKVEAPGAPDPL
Mb3300|M.bovis_AF2122/97 MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAAR
Rv3272|M.tuberculosis_H37Rv MPTSNPAKPLDGFRVLDFTQNVAGPLAGQVLVDLGAEVIKVEAPGGEAAR
.* .. *:.. :.* * * *:** ***:* *
MSMEG_4120|M.smegmatis_MC2_155 RGWGPPFVD-GDSAWFASANRNKRSLVLDLRSGTGRDVLLRLIDSADAFL
MAV_1892|M.avium_104 RGY-DHSVH-GDSSYFVWLNRGKESLTLDLKTLEGQRILRQLLANSDVLV
MAB_0824|M.abscessus_ATCC_1997 RQWGPPYDSDGQATYFNSVNRNKQSVVLDLTSPDGQHRARELAGRADVVV
Mvan_1855|M.vanbaalenii_PYR-1 RQWGPPYDSSGVATYFNAVNRNKRSVVLDLSTPDGRQQARDLVAGADIVV
Mflv_4465|M.gilvum_PYR-GCK RTWGQAELD-GHHFFWTVHARNKKAVTLNLRVPEGRDLFLDLVERSDVIV
TH_3905|M.thermoresistible__bu RTWGQAELD-GHHFFWTVHARNKKAITLNLREPAGRDVFLELVERSDIVV
MMAR_1494|M.marinum_M RTWGQAEVD-GHHVFWTVHARNKRAITLDLRRPQGRELFLELVDKSDIVV
MUL_2446|M.ulcerans_Agy99 RTWGQAEVD-GHHVFWTVHARNKRAITLDLRRPQGRELFLELVDKSDIVV
Mb3300|M.bovis_AF2122/97 QITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTADVVL
Rv3272|M.tuberculosis_H37Rv QITSVLPGRPPLATYFLPNNRGKKSVTVDLTTEQAKQQMLRLADTADVVL
: :: *.*.::.::* .: * :* .:
MSMEG_4120|M.smegmatis_MC2_155 QSMNPAKLVRMGIDAENLHRRNPRLVYCAMSGFGLDGPDSNLPGYDLVAQ
MAV_1892|M.avium_104 QNLGPGATTRLSLDATTLTPEYPRLIVCDITGYGGTGPWRDRKAYDLLVQ
MAB_0824|M.abscessus_ATCC_1997 ENFRAGTMEKFGLGYQSLKQLNPGLIYCAITGFGR-GAGADLPGYDLLVQ
Mvan_1855|M.vanbaalenii_PYR-1 ENFRPGTMERLGLGYEDLRAVRPDVIYCSITGFGR-GGGAALPGYDLLVQ
Mflv_4465|M.gilvum_PYR-GCK ENFRPGTLEKWNLGYDVLRERNRGIILVRVSGYGQTGPDAHKAGYASVAE
TH_3905|M.thermoresistible__bu ENFRPGTLERWDLGYDVLRSHNNRVILVRVSGYGQTGPDAHKAGYASVAE
MMAR_1494|M.marinum_M ENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQTGPDAHKAGYASVAE
MUL_2446|M.ulcerans_Agy99 ENFRPGTLEKWDLGYDVLRERNPGIILVRVSGYGQTGPDAHKAGYASVAE
Mb3300|M.bovis_AF2122/97 EAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDLVVA
Rv3272|M.tuberculosis_H37Rv EAFRPGTMEKLGLGPDDLRSRNPNLIYARLTAYGGNGPHGSRPGIDLVVA
: : .. : .:. * :: ::.:* * . :.
MSMEG_4120|M.smegmatis_MC2_155 ARSGLMSVTGEKGRSPQRVSTALSDIATGMCAALAVSAALVQQAKTGKGA
MAV_1892|M.avium_104 AEAGLLSVTGS-GDEVARTGVSIADIAAGMFAFSGILTALYVRATTGDVR
MAB_0824|M.abscessus_ATCC_1997 AVGGLMSVTGPDAAHPSKVGVALVDVLTALHALSGILAALSYRDRTGQGQ
Mvan_1855|M.vanbaalenii_PYR-1 AVGGLMSVTGTEPGDPTKAGVALVDVLAGLHALSGILAALHHRGRTGEGQ
Mflv_4465|M.gilvum_PYR-GCK AASGLRHMNGFPGGPPPRLALSLGDSLAGMFAAQGALAALYRRSVTGEGQ
TH_3905|M.thermoresistible__bu AASGLRHLNGFPGGPPPRLALSLGDTLAGMFAAQGAMAALYRRTVTGEGQ
MMAR_1494|M.marinum_M AASGLRHLNGFPGGPPPRLALSLGDSLAGMFGAQGALAALYRRSVTGTGQ
MUL_2446|M.ulcerans_Agy99 AASGLRHLNGFPGGPPPRLALSLGDSLAGMFGPQGALAALYRRSVTGTGQ
Mb3300|M.bovis_AF2122/97 AEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERNGVAD
Rv3272|M.tuberculosis_H37Rv AEAGMTTGMPTPEGKPQIIPFQLVDNASGHVLAQAVLAALLHRERNGVAD
* .*: : * :. . :** : .*
MSMEG_4120|M.smegmatis_MC2_155 TIDVSLLDTDLALMAPRIAAYHAGDP------EPGPSGGTDSVL----AV
MAV_1892|M.avium_104 PVSVSLFESLVELVSQPAYYAHYGGT------APPRTGARHATI----AP
MAB_0824|M.abscessus_ATCC_1997 RVDTDLMSVLLSSLVNQASGYLGAGV------VPEALGNRHPSI----AP
Mvan_1855|M.vanbaalenii_PYR-1 RVDTDLLSVLLSSMVNQASGFLGAGV------VPAMMGNRHPSI----AP
Mflv_4465|M.gilvum_PYR-GCK IVDAALTESCLAVQESTIPDYDVGGV------VRGPSGTRLEGI----AP
TH_3905|M.thermoresistible__bu VVDAALTEACLAVQESTIPDYDIGGV------VRGPSGTRLEGI----AP
MMAR_1494|M.marinum_M VVDVALTESCLALQESTISDYDVGGV------VRGPSGTRLEGI----AP
MUL_2446|M.ulcerans_Agy99 VVDVALTESCLALQESTISDYDVGGV------VRGPSGTRLKGI----AP
Mb3300|M.bovis_AF2122/97 VVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGVGFATQP
Rv3272|M.tuberculosis_H37Rv VVQVAMYDVAVGLQANQLMMHLNRAASDQPKPEPAPKAKRRKGVGFATQP
:.. : . : . :
MSMEG_4120|M.smegmatis_MC2_155 YQSFEASDR-SIVVAIGNDAMWLRFC-AAIDLPDLASDPDLADNAGRRAQ
MAV_1892|M.avium_104 YGPFTAGDGGTVLLAVQNQREWRRLCDEVLATPGLCEDPRFVTNPDRVTH
MAB_0824|M.abscessus_ATCC_1997 YQTFETADR-PIAIAVGNDKQFRLLV-QALEMPRLARDDRFATNPLRVRH
Mvan_1855|M.vanbaalenii_PYR-1 YQTFDTADR-PIAVAVGNDKQFRAFS-TAIGQPELADDPRFVTNPARVAN
Mflv_4465|M.gilvum_PYR-GCK SNIYPTADGSWVVIAANQDTVFRRLC-AAMGQPELATDERFADHVARGRN
TH_3905|M.thermoresistible__bu SNIYRSADGSWVVIAANQDTVFRRLC-AAMGRPELATDDRFATHTARGRN
MMAR_1494|M.marinum_M SNIYRSADESWVVIAANQDTVFTRLC-QAMGCPELATDDRFATHRARGRN
MUL_2446|M.ulcerans_Agy99 SNIYRSADESWVVIAANQDTVFTRLC-QAMGCPELATDDRFATHRARGRN
Mb3300|M.bovis_AF2122/97 SDAFRTADG-YIVISAYVPKHWQKLC-YLIGRPDLVEDQRFAEQRSRSIN
Rv3272|M.tuberculosis_H37Rv SDAFRTADG-YIVISAYVPKHWQKLC-YLIGRPDLVEDQRFAEQRSRSIN
: :.* : :: : : : * * * :. : * :
MSMEG_4120|M.smegmatis_MC2_155 RPRITALIAERISTRTAAEWVRILNDVDVPVSLVQTLSEVVKDPQVVAR-
MAV_1892|M.avium_104 RDELEAIIHAAIASMTADELAHRLEAAGIANARMNDVETLWSHPVLAGR-
MAB_0824|M.abscessus_ATCC_1997 RGELVRVLEQRLREKNADDWYDTLTAVGVPAGPINDIAEAFRFAERLGL-
Mvan_1855|M.vanbaalenii_PYR-1 RDALCALIVPALKAHGADHWYAKLTTVGVPAGPINDLSEAFAFARGLGI-
Mflv_4465|M.gilvum_PYR-GCK QDEIDKIIGGWAAQRQPDEIISTLSEAGVISGPINTVAEVVEDPQLQARG
TH_3905|M.thermoresistible__bu QDELDKIIADWAAERAPGEIIDTLNAAGVIAGPINTVAEVVEDPQLRARG
MMAR_1494|M.marinum_M QDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEVVKDRQLRARG
MUL_2446|M.ulcerans_Agy99 QDELDKIIGAWAAQRQPDEIIETLSAAGVIAGPINTVAEVVKDRQLRARG
Mb3300|M.bovis_AF2122/97 YAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDTPLFAES-
Rv3272|M.tuberculosis_H37Rv YAELTAELELALASKTATEWVQLLQANGLMACLAHTWKQVVDTPLFAEN-
: : . . * .: :
MSMEG_4120|M.smegmatis_MC2_155 ---GSLMPVPGSTERLATVHSPFRFDGLAVRNKRFPDLGADSRRVLAELG
MAV_1892|M.avium_104 ---DRWREVRAPGGAIEALLPPATLRDVEPQLGDVPGLAAHSRMILRELG
MAB_0824|M.abscessus_ATCC_1997 ---DVAVTVPGSPE--PQVANPISMSKTPVVYRNGPPRLGQSRA------
Mvan_1855|M.vanbaalenii_PYR-1 ---DAAVQVPGSPA--PQVANPVTMSATPVSYRSGPPALGDSPIAEKP--
Mflv_4465|M.gilvum_PYR-GCK MIADHWDERIGRNVKGPGVVPVLSETPGTIRSAGSARPGQHNDEIYRDLL
TH_3905|M.thermoresistible__bu MIADHFDERIGRNVKGPGVVPVLSESPGTIRNAGPARPGQHNEEIYTGLL
MMAR_1494|M.marinum_M MLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQHNDDVYIGLL
MUL_2446|M.ulcerans_Agy99 MLVEHYDERIGRNVLGPGIVPALSESPGQVRSAGPARPGQHNDDVYIGLL
Mb3300|M.bovis_AF2122/97 ---DLTLEVGRGADTITVIRTPARYASFRAVVTDPPPTAGEHNAVFLARP
Rv3272|M.tuberculosis_H37Rv ---DLTLEVGRGADTITVIRTPARYASFRAVVTDPPPTAGEHNAVFLARP
: . .
MSMEG_4120|M.smegmatis_MC2_155 -YGPDDIAALFAAGVVSEPAGAGEVVS
MAV_1892|M.avium_104 -YTNEAIADLVRSGVTTVASDH-----
MAB_0824|M.abscessus_ATCC_1997 ---------------------------
Mvan_1855|M.vanbaalenii_PYR-1 ---------------------------
Mflv_4465|M.gilvum_PYR-GCK GRSAAELDKLQEEGVL-----------
TH_3905|M.thermoresistible__bu GKTAAELRQLRAQGVI-----------
MMAR_1494|M.marinum_M GKSIEELEQLRAEEVL-----------
MUL_2446|M.ulcerans_Agy99 GKSIEELEQLRAVEVL-----------
Mb3300|M.bovis_AF2122/97 ---------------------------
Rv3272|M.tuberculosis_H37Rv ---------------------------