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PVPIERGKHRRSLLRDQAYVSIRDAIVNGTLAPGEKLRDPELEEWLGISRTPIREALARLETAGLVHTTP GRSTVVAAIEPQAVLNAQSVAAAMHALAVRTAVPLMDKSDFDAMTAANHAFAQAISRGDPEAAMRSDDHF HGVAVQASGNEVIEQVLEQVTPVLRRLEYLRFSALSGRESIEQHRRIVSLCRKRDAEGAAAATEQNWQTL SQVVEKLAAEETDTDG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6738 | - | - | 100% (227) | transcriptional regulator YdhC |
| M. smegmatis MC2 155 | MSMEG_4057 | - | 9e-21 | 30.85% (201) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_1317 | - | 2e-16 | 27.18% (195) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0170c | - | 5e-14 | 27.94% (204) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4366 | - | 2e-13 | 28.11% (185) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0165c | - | 2e-11 | 31.65% (139) | GntR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1705c | - | 1e-64 | 57.21% (222) | GntR family transcriptional regulator |
| M. marinum M | MMAR_0408 | - | 3e-17 | 30.15% (199) | GntR family transcriptional regulator |
| M. avium 104 | MAV_5020 | - | 2e-18 | 30.58% (206) | transcriptional regulator, GntR family protein |
| M. thermoresistible (build 8) | TH_3038 | - | 5e-18 | 29.10% (189) | PUTATIVE putative transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_1058 | - | 3e-16 | 29.65% (199) | GntR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_3051 | - | 2e-14 | 31.66% (199) | GntR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6738|M.smegmatis_MC2_155 ----------------------------------------------MPVP
MAB_1705c|M.abscessus_ATCC_199 ----------------------------------------------MPVP
Mb0170c|M.bovis_AF2122/97 MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
Rv0165c|M.tuberculosis_H37Rv MIKHDVVWVTLWPERPNNKPPPSPRQVPGNPGPTLKVLASHVNAPLSAKP
MMAR_0408|M.marinum_M -----------------------------------------MNIPLSARR
MUL_1058|M.ulcerans_Agy99 -----------------------------------------MNILLSARR
MAV_5020|M.avium_104 ---------------------------------------------MSMQP
Mflv_4366|M.gilvum_PYR-GCK ---------------------------------------------MTTPE
TH_3038|M.thermoresistible__bu --------------------------------------------------
Mvan_3051|M.vanbaalenii_PYR-1 --------------------------------------------MAAPTE
MSMEG_6738|M.smegmatis_MC2_155 IERGKHRRSLLRDQAYVSIRDAIVNGTLAPGEKLRDPELEEWLGISRTPI
MAB_1705c|M.abscessus_ATCC_199 PSEGIAARSLLRDNAYKALRTAIVDGTLAPGERLRDDELSRWLGVSRTPI
Mb0170c|M.bovis_AF2122/97 RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
Rv0165c|M.tuberculosis_H37Rv RSQLPLRRAQLSDEVAGHLRAAIMSGALRSGTFIRLDETAAELGVSVTPV
MMAR_0408|M.marinum_M KSRRPLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITPV
MUL_1058|M.ulcerans_Agy99 ESRRPLRRAQLSDEVAGHLRAAIMSGTLRPGTFIRLDETAAELGVSITPV
MAV_5020|M.avium_104 RSRRPLRRAQLSDEVAGHLRAAIMSGALRPGTFIRLDETAAELGVSVTPV
Mflv_4366|M.gilvum_PYR-GCK FAARP----QLAEDVARFVRRRIFDGTYPAGRYIRLEQLAAELGISVTPV
TH_3038|M.thermoresistible__bu MSRTVESNGDASERAYQAVLQMILDGEAPAGSWLREQTLAEQIGVSRTPV
Mvan_3051|M.vanbaalenii_PYR-1 EPSRLALPATLVEVAGNRLRDAILSGELAPGEKIIEEQLCADFGISRAPL
: . : *..* .* : :*:* :*:
MSMEG_6738|M.smegmatis_MC2_155 REALARLETAGLVHTTPGRSTVVAAIEPQAVLNAQSVAAAMHALAVRTAV
MAB_1705c|M.abscessus_ATCC_199 REALARLEQAGLVQTQPGRHTIVSPIDVREARAAQSVAAAMHELAVREAI
Mb0170c|M.bovis_AF2122/97 REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
Rv0165c|M.tuberculosis_H37Rv REALLKLRGEGMVGLEPHRGHVVLPLTRQDIDDIFWLQATIAQELATSAT
MMAR_0408|M.marinum_M REALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTAT
MUL_1058|M.ulcerans_Agy99 REALLKLRGEGMVQLEPHRGHVVLPLTRQDIDDIFWLQATIARELAVTAT
MAV_5020|M.avium_104 REALLKLRGEGMVQLEPHRGHVVLPLTRQDIEDIFWLQATIAKELAAAAT
Mflv_4366|M.gilvum_PYR-GCK REALFGLRAEGLLTQQPRRGFVVSPITERDIADVSDVQAHIGGVLASRAA
TH_3038|M.thermoresistible__bu RQALNRLAAEGAIELVPNRGAQVVSFSDEDVEALFDLRARFEPLAVRLAV
Mvan_3051|M.vanbaalenii_PYR-1 REALRRLAQQGLVEHLPRRGSRVTEWSPTDILQLFELRNVLERHAIESAL
*:** * * : * * * : : *
MSMEG_6738|M.smegmatis_MC2_155 PLMDKSDFDAMTAANHAFAQAISRG--DPEAAMRSDDHFHGVAVQASGNE
MAB_1705c|M.abscessus_ATCC_199 TNISPGDLAAMRHANTRFAAALDAH--DPDAALAADDEFHAVAVEASANP
Mb0170c|M.bovis_AF2122/97 AHITDVEIDELDRINNALAGAIGSG--DAKTIASIEFAFHRVFNKASRRI
Rv0165c|M.tuberculosis_H37Rv AHITDVEIDELDRINNALAGAIGSG--DAKTIASIEFAFHRVFNKASRRI
MMAR_0408|M.marinum_M ERISEIDIGELEHINDALTAAVGAG--DTEAIAALEFAFHRVLNQSSGRI
MUL_1058|M.ulcerans_Agy99 ERISEVVIGELEHINDALTAAVGAG--DTEAIAALEFAFHRVLNQSSGRI
MAV_5020|M.avium_104 DHITDTEIDELDRINDALAAAVGSG--DAETIAGLEFGFHRVFNQASGRI
Mflv_4366|M.gilvum_PYR-GCK ELITDEQLAELERIQDELEAAYDAV--DHEAAVRLNHAFHRGVNIAAGSP
TH_3038|M.thermoresistible__bu PQLTEERIAELADLATRMEALLDRRPLDTHQMSRLNNAFHGIFLAEAGNR
Mvan_3051|M.vanbaalenii_PYR-1 PLADLD--RDLEPVRAALEQMDASS--DVLSLDDAHRAFHAAVVGLAKNR
: : * . ** :
MSMEG_6738|M.smegmatis_MC2_155 VIEQVLEQVTP-VLRRLEY-LRFSALSGRESIEQHRRIVSLCRKRDAEGA
MAB_1705c|M.abscessus_ATCC_199 YIAAVLEQVTP-VLRRLER-IRFASRDGRHSVALHEQIIARCEAGDSEGA
Mb0170c|M.bovis_AF2122/97 KLAWFLLNAAR-YMPAQVF-AADPRW-GADAVNSHRQLIAALRRRDTAAV
Rv0165c|M.tuberculosis_H37Rv KLAWFLLNAAR-YMGAGVR-GRP-----AMGRGRGEQSSAADRR---AAP
MMAR_0408|M.marinum_M KLAWFLLNAAR-YMPAQLY-ASDPQW-GAAAVDNHRQLIAALRRRDTAAV
MUL_1058|M.ulcerans_Agy99 KLAWFLLNAAR-YMPAQLY-ASDPQW-GAAAVDNHRQLIAALRRRDTAAV
MAV_5020|M.avium_104 KLAWFLLNAAR-YMPVLVY-AADPQW-GRAAVDNHRQLIAALRRRDTAAV
Mflv_4366|M.gilvum_PYR-GCK KLAQLMGQITR-FALESVY-PTVEGW-PAHSMNDHRVLLAALRKRDGTAA
TH_3038|M.thermoresistible__bu HLTAAMQAVVRPALVTLTF-QKYSERALRLSMHHHAELVEAARARDPEWA
Mvan_3051|M.vanbaalenii_PYR-1 QLDIALEPILLKLQLPMARNMREEARQHAGPGRRHRPGAADEGIGRHKAI
: :
MSMEG_6738|M.smegmatis_MC2_155 AAATEQNWQTLSQVVEKLAAEETDTDG--
MAB_1705c|M.abscessus_ATCC_199 GRAARDNWHTLIAAPEGAAHEERGAG---
Mb0170c|M.bovis_AF2122/97 IEHTVWQFTDGARRLTEALAETEVFG---
Rv0165c|M.tuberculosis_H37Rv PRHSRR---NRAHRLAVHRWGTQADGGPG
MMAR_0408|M.marinum_M IEHSVWQFTDAAHRLTQMLETNGIFN---
MUL_1058|M.ulcerans_Agy99 IEHSVWQFTDAAHRLTQMLETNGIFN---
MAV_5020|M.avium_104 IEHTVWQFTDAAARLTAMRDRTGTPSNRG
Mflv_4366|M.gilvum_PYR-GCK RDAMSEHLCAAAGPLIDHLTTRGVIG---
TH_3038|M.thermoresistible__bu EAVMRAHILAARHAGE-------------
Mvan_3051|M.vanbaalenii_PYR-1 LSALETNDPAAVVTAIRDHGHLHYLGLAP