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VNDSRNSGTLAVLVHGAWHSSLHWAAAQRGLARRGVASIAVDLPGHGLDAPVPSGYLTAGQPGLETEKSA LADITMDDLADAVVDALAEVRSRFARVLLVAHSAGGGPASLAAEKAPELVDHLVYLAAFVPAARPRFTDY INAPENADVVALPIFSDPANLGAHRLNPLSSDAIEVDAIRRAFLTDMPPDAPEGWRHLLHPDEPYASLSA PVPVTPRRWGRIPRTYIRLDGDRALAPTTQNLMIAEADRLTPDNPFGVRSLPGDHSPMVHRPGELADLLA GI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6710 | - | - | 100% (282) | hydrolase, alpha/beta fold family protein |
| M. smegmatis MC2 155 | MSMEG_1797 | - | 9e-13 | 28.70% (230) | salicylate esterase |
| M. smegmatis MC2 155 | MSMEG_6838 | - | 2e-09 | 28.80% (184) | putative esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2734 | - | 1e-06 | 31.97% (122) | hydrolase |
| M. gilvum PYR-GCK | Mflv_2476 | - | 5e-15 | 28.88% (277) | esterase EstC, putative |
| M. tuberculosis H37Rv | Rv2715 | - | 1e-06 | 31.97% (122) | hydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2946c | - | 1e-06 | 35.29% (119) | Alpha/beta hydrolase fold |
| M. marinum M | MMAR_1997 | - | 4e-06 | 31.71% (123) | hydrolase |
| M. avium 104 | MAV_2604 | - | 5e-09 | 28.36% (275) | hydrolase, alpha/beta fold family protein, putative |
| M. thermoresistible (build 8) | TH_2893 | - | 7e-08 | 24.63% (272) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3358 | - | 2e-06 | 31.71% (123) | hydrolase |
| M. vanbaalenii PYR-1 | Mvan_4177 | - | 2e-15 | 29.93% (284) | esterase EstC, putative |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2476|M.gilvum_PYR-GCK -----------------------MRFILVHGGFHAAWCWERTAAALRALG
Mvan_4177|M.vanbaalenii_PYR-1 -----------------------MRFVLVHGGFHAAWCWERTIDALQALG
Mb2734|M.bovis_AF2122/97 -----MTERKRNLRPVRDVAPPTLQFRTVHG-YRRAFRIAGSGPAILLIH
Rv2715|M.tuberculosis_H37Rv -----MTERKRNLRPVRDVAPPTLQFRTVHG-YRRAFRIAGSGPAILLIH
MMAR_1997|M.marinum_M -----MTERKRNLRPVREVTAPSLQFRTIHG-YKRAFRIAGSGPAILLIH
MUL_3358|M.ulcerans_Agy99 -----MTERKRNLRPVREVTAPSLQFRTIHG-YKRAFRIAGSGPAILLIH
TH_2893|M.thermoresistible__bu ---------------------MAKPILLVHGAFSGSWVWDQVVAELASCG
MSMEG_6710|M.smegmatis_MC2_155 ---------------MNDSRNSGTLAVLVHGAWHSSLHWAAAQRGLARRG
MAV_2604|M.avium_104 --------------------MALPDLVLVHGGEHAGDCWDLVIAELRRQE
MAB_2946c|M.abscessus_ATCC_199 MIAESRAEYGGVVTRVLSVPGGGPPIVLLHGYSDSALTWRPVLARLASAG
:** . :
Mflv_2476|M.gilvum_PYR-GCK -------------------HDVTAVDLPGHG--ALADQESTLANRRDAIV
Mvan_4177|M.vanbaalenii_PYR-1 -------------------HDAVAVDLPGHG--DRVDEESTLANRREAVV
Mb2734|M.bovis_AF2122/97 GIGDNSTTWNGVHAKLAQRFTVIAPDLLGHGQSDKPRADYSVAAYANGMR
Rv2715|M.tuberculosis_H37Rv GIGDNSTTWNGVHAKLAQRFTVIAPDLLGHGQSDKPRADYSVAAYANGMR
MMAR_1997|M.marinum_M GIGDNSTTWTGIHAKLAQRFTVIAPDLLGHGRSDKPRADYSIAAYANGMR
MUL_3358|M.ulcerans_Agy99 GIGDNSTTWTGIHAKLAQRFTVIAPDLLGHGRSDKPRADYSIAAYANGMR
TH_2893|M.thermoresistible__bu -------------------VQARTVELSSRK------PDGTLARDAHVVR
MSMEG_6710|M.smegmatis_MC2_155 -VASIAVDLPGHGLDAPVPSGYLTAGQPGLETEKSALADITMDDLADAVV
MAV_2604|M.avium_104 -----------------PGLRTLAVDLPGHGNKPGDLATVTIADWVDSVI
MAB_2946c|M.abscessus_ATCC_199 -------------------RAAIAVDLPGFGHAAPRPPGPLLAQFDVFAD
: . :
Mflv_2476|M.gilvum_PYR-GCK AAMQAGD---EKCVLVGHSGGGFDATLAADARPDLVSHITYLAAA-LPRE
Mvan_4177|M.vanbaalenii_PYR-1 AAMQAGG---GKCVLVGHSGGGFDATLAADARPDLVHHIVYLAAA-LPRE
Mb2734|M.bovis_AF2122/97 DLLSVLDI--ERVTIVGHSLGGGVAMQFAYQFPQLVDRLILVSAGGVTKD
Rv2715|M.tuberculosis_H37Rv DLLSVLDI--ERVTIVGHSLGGGVAMQFAYQFPQLVDRLILVSAGGVTKD
MMAR_1997|M.marinum_M DLLSVLDI--ERVTIIGHSLGGGVAMQFAYQFPQLVDRLILVGAGGVTKD
MUL_3358|M.ulcerans_Agy99 DLLSVLDI--ERVTIIGHSLGGGVAMQFAYQFPQLVDRLILVGAGGVTKD
TH_2893|M.thermoresistible__bu DALKQFD---QPAVLVGHSYGG-AVITEASADNDHVAHLIYVCAA-LPQA
MSMEG_6710|M.smegmatis_MC2_155 DALAEVRSRFARVLLVAHSAGGGPASLAAEKAPELVDHLVYLAAF-VPAA
MAV_2604|M.avium_104 ADIEEAGLG--DIVIVGHSMAGVTVPGVVAKLGSSRVREMVLATAFVPPQ
MAB_2946c|M.abscessus_ATCC_199 AVLAAAG----PAVLVGNSLGAATAVRAAARRENEVKALIALDDP--LNS
: ::.:* .. . . . :
Mflv_2476|M.gilvum_PYR-GCK GRTYPEAMAMRDDDNGPVELGEDFDGDVGEMLGYLHFDDTGAMKFADFDG
Mvan_4177|M.vanbaalenii_PYR-1 GRTYPEAMAMRDAEQGPAELGDEFDGDVGEMLGYLNFDEDGAMTFADFEG
Mb2734|M.bovis_AF2122/97 VNIVFRLASLPMGSEAMALLRLPLVLPAVQIAGRIVGKAIGTTSLGHDLP
Rv2715|M.tuberculosis_H37Rv VNIVFRLASLPMGSEAMALLRLPLVLPAVQIAGRIVGKAIGTTSLGHDLP
MMAR_1997|M.marinum_M VNVVFRLASLPMGAEALALLRLPMVLPTVQLAGKVLGMALGSTALGQDLP
MUL_3358|M.ulcerans_Agy99 VNVVFRLASLPMGAEALALLRLPMVLPTVQLAGKVLGMALGSTALGQDLP
TH_2893|M.thermoresistible__bu GESVSDVLARDPDPQG-------------DLAPALEVREDGTATMKR-DA
MSMEG_6710|M.smegmatis_MC2_155 RPRFTDYIN---APENADVVALPIFSDPANLGAHRLN--PLSSDAIEVDA
MAV_2604|M.avium_104 GSAIADTLGGPLAVFAR------------------RAARIGRPMKIPAPA
MAB_2946c|M.abscessus_ATCC_199 RHLIARIVRRWSVPEVFWAWVSRMPVPAGTLRRAARYFVPKMLYGPGVAA
Mflv_2476|M.gilvum_PYR-GCK AWKYFYHDCDEETARWAFER-LGPERFGDTTVTPVSVPNFWAADLPRSFI
Mvan_4177|M.vanbaalenii_PYR-1 AWKYFYHDCDEATARWAFER-LGPERFGDTTVTPVSVPDFWAADLPRSFI
Mb2734|M.bovis_AF2122/97 NVLRILDDLPEPTASAAFGRTLRAVVDWRGQMVTMLDRCYLTEAIPVQII
Rv2715|M.tuberculosis_H37Rv NVLRILDDLPEPTASAAFGRTLRAVVDWRGQMVTMLDRCYLTEAIPVQII
MMAR_1997|M.marinum_M NVLRILDDLPEPTASSAFTRTLRAVVDWRGQIVTMLDRCYLTQAIPVQII
MUL_3358|M.ulcerans_Agy99 NVLRILDDLPEPTASSAFTRTLRAVVDWRGQIVTMLDRCYLTQAIPVQII
TH_2893|M.thermoresistible__bu ARQALFNDATEEQFESVVDK-LGPHAMG---TLSEPVTGLGWQQHPATYV
MSMEG_6710|M.smegmatis_MC2_155 IRRAFLTDMPPDAPEG-WRHLLHPDEPYASLSAPVPVTPRRWGRIPRTYI
MAV_2604|M.avium_104 ARWAFCNGMTAAQRRLTMSKLQAESARVPGEPVDRSG---LPADVPRTWI
MAB_2946c|M.abscessus_ATCC_199 DPEVVAYWCELISGPSAVARLGRDACRYAHEALGSHSG--IEVSCPTLVV
. : * :
Mflv_2476|M.gilvum_PYR-GCK VCEQDQAMPRWLADTVARRLGVDQLTIDAS-------HSPFLSRPREFAD
Mvan_4177|M.vanbaalenii_PYR-1 VCEQDRSMPRWLADTVARRLGVEQLTIDAS-------HSPFLSRPRELAE
Mb2734|M.bovis_AF2122/97 WGTKDVVLPVRHAHMAHAAMPGSQLEIFEGS-----GHFPFHDDPARFID
Rv2715|M.tuberculosis_H37Rv WGTKDVVLPVRHAHMAHAAMPGSQLEIFEGS-----GHFPFHDDPARFID
MMAR_1997|M.marinum_M WGSRDAVVPVRHAEMAHAAMPGSKLEVFEGS-----GHFPFHDDPARFID
MUL_3358|M.ulcerans_Agy99 WGSRDAVVPVRHAEMAHAAMPGSKLEVFEGS-----GHFPFHDDPARFID
TH_2893|M.thermoresistible__bu IALRDQMFSVALQEEFASHVG-TVAKIDTG-------HGPMATRPAELAE
MSMEG_6710|M.smegmatis_MC2_155 RLDGDRALAPTTQNLMIAEADRLTPDNPFGVRSLPGDHSPMVHRPGELAD
MAV_2604|M.avium_104 LTTRDRALSVASQHASIAALGGVETVIPVDA-----CHEVMFSHPERLAQ
MAB_2946c|M.abscessus_ATCC_199 HGGRDRIIPIHSSGALQQQIPGSELVILPAS-----GHCPQLDNPDEVTR
* .. * * ..
Mflv_2476|M.gilvum_PYR-GCK LLVHATTTTP-----VAPLRPL----------------------------
Mvan_4177|M.vanbaalenii_PYR-1 LLVRATTTTP-----VSPLVPH----------------------------
Mb2734|M.bovis_AF2122/97 IVERFMDTTEPAEYDQAALRALLRRGGGEATVTGSADTRVAVLNAIGSNE
Rv2715|M.tuberculosis_H37Rv IVERFMDTTEPAEYDQAALRALLRRGGGEATVTGSADTRVAVLNAIGSNE
MMAR_1997|M.marinum_M IVLRFIDSTQPPEYDQAALRELLRTGGGERTVSGPADTRVAVLSAMGSDE
MUL_3358|M.ulcerans_Agy99 IVLRFIDSTQPPEYDQAALRELLRTGGGERTVSDPADTRVAVLSAMGSDE
TH_2893|M.thermoresistible__bu IIATAAR-------------------------------------------
MSMEG_6710|M.smegmatis_MC2_155 LLAGI---------------------------------------------
MAV_2604|M.avium_104 ILIERCRLRGVGIR------------------------------------
MAB_2946c|M.abscessus_ATCC_199 LIVDFCDRISEPRQPDAAHSG-----------------------------
::
Mflv_2476|M.gilvum_PYR-GCK ----
Mvan_4177|M.vanbaalenii_PYR-1 ----
Mb2734|M.bovis_AF2122/97 RSAT
Rv2715|M.tuberculosis_H37Rv RSAT
MMAR_1997|M.marinum_M RSAT
MUL_3358|M.ulcerans_Agy99 RSAT
TH_2893|M.thermoresistible__bu ----
MSMEG_6710|M.smegmatis_MC2_155 ----
MAV_2604|M.avium_104 ----
MAB_2946c|M.abscessus_ATCC_199 ----