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MRFVLVHGGFHAAWCWERTIDALQALGHDAVAVDLPGHGDRVDEESTLANRREAVVAAMQAGGGKCVLVG HSGGGFDATLAADARPDLVHHIVYLAAALPREGRTYPEAMAMRDAEQGPAELGDEFDGDVGEMLGYLNFD EDGAMTFADFEGAWKYFYHDCDEATARWAFERLGPERFGDTTVTPVSVPDFWAADLPRSFIVCEQDRSMP RWLADTVARRLGVEQLTIDASHSPFLSRPRELAELLVRATTTTPVSPLVPH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4177 | - | - | 100% (261) | esterase EstC, putative |
| M. vanbaalenii PYR-1 | Mvan_3363 | - | 4e-12 | 37.38% (107) | hypothetical protein Mvan_3363 |
| M. vanbaalenii PYR-1 | Mvan_4902 | - | 2e-10 | 28.74% (247) | hypothetical protein Mvan_4902 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0046c | - | 1e-07 | 28.02% (207) | hydrolase |
| M. gilvum PYR-GCK | Mflv_2476 | - | 1e-135 | 85.77% (260) | esterase EstC, putative |
| M. tuberculosis H37Rv | Rv0045c | - | 1e-07 | 28.02% (207) | hydrolase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0554 | - | 5e-07 | 36.56% (93) | alpha/beta family hydrolase |
| M. marinum M | MMAR_0064 | - | 9e-07 | 31.08% (148) | hydrolase |
| M. avium 104 | MAV_2604 | - | 8e-14 | 29.53% (254) | hydrolase, alpha/beta fold family protein, putative |
| M. smegmatis MC2 155 | MSMEG_6710 | - | 2e-15 | 29.93% (284) | hydrolase, alpha/beta fold family protein |
| M. thermoresistible (build 8) | TH_2893 | - | 4e-19 | 29.27% (246) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_0147 | bpoB | 8e-06 | 31.91% (94) | peroxidase BpoB |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0046c|M.bovis_AF2122/97 MLSD---DELTGLDEFALLAENAEQAGVNGPLPEVERVQAGA----ISAL
Rv0045c|M.tuberculosis_H37Rv MLSD---DELTGLDEFALLAENAEQAGVNGPLPEVERVQAGA----ISAL
MMAR_0064|M.marinum_M -MTDSFPDDLTGLTEFDLLAENAEQAGVTGPLPEVERIEVGAAETRISAL
Mvan_4177|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_2476|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6710|M.smegmatis_MC2_155 ------------------------------------------------MN
MAV_2604|M.avium_104 --------------------------------------------------
TH_2893|M.thermoresistible__bu --------------------------------------------------
MAB_0554|M.abscessus_ATCC_1997 --------------------------------------MSGMQRDHITDH
MUL_0147|M.ulcerans_Agy99 ---------------------MSAMSNNPRTVEFSGTEGITLVADEWNRD
Mb0046c|M.bovis_AF2122/97 RWGGSAPRVIFLHGGGQNAHTWD---TVIVG--LGEPALAVDLPGHG---
Rv0045c|M.tuberculosis_H37Rv RWGGSAPRVIFLHGGGQNAHTWD---TVIVG--LGEPALAVDLPGHG---
MMAR_0064|M.marinum_M RWGGRAPRVIFLHGGGQNAHTWD---TVIVG--LGEPALAVDLPGHG---
Mvan_4177|M.vanbaalenii_PYR-1 ------MRFVLVHGGFHAAWCWERTIDALQA--LGHDAVAVDLPGHG---
Mflv_2476|M.gilvum_PYR-GCK ------MRFILVHGGFHAAWCWERTAAALRA--LGHDVTAVDLPGHG---
MSMEG_6710|M.smegmatis_MC2_155 DSRNSGTLAVLVHGAWHSSLHWAAAQRGLAR--RGVASIAVDLPGHGLDA
MAV_2604|M.avium_104 ---MALPDLVLVHGGEHAGDCWDLVIAELRRQEPGLRTLAVDLPGHG---
TH_2893|M.thermoresistible__bu ----MAKPILLVHGAFSGSWVWDQVVAELAS--CGVQARTVELSSRK---
MAB_0554|M.abscessus_ATCC_1997 GGHADGPTLVLVHGLMGRGTTWSRQLPWLRG---LGRVYTYDAPWHR---
MUL_0147|M.ulcerans_Agy99 TAASGRPTILMLHGGCQNRFSWKNTGQILAD--TGLHVIALDTRGHG---
:::** * : : : :
Mb0046c|M.bovis_AF2122/97 ----------------HSAWREDGNYSPQLNSETLAPVLRELA-PGAEFV
Rv0045c|M.tuberculosis_H37Rv ----------------HSAWREDGNYSPQLNSETLAPVLRELA-PGAEFV
MMAR_0064|M.marinum_M ----------------HSAWRQDGDYSPQHNADALVPALRELA-SEAEFV
Mvan_4177|M.vanbaalenii_PYR-1 ----------------DRVDEE----STLANRREAVVAAMQAG-GGKCVL
Mflv_2476|M.gilvum_PYR-GCK ----------------ALADQE----STLANRRDAIVAAMQAG-DEKCVL
MSMEG_6710|M.smegmatis_MC2_155 PVPSGYLTAGQPGLETEKSALADITMDDLADAVVDALAEVRSR-FARVLL
MAV_2604|M.avium_104 ------------------NKPGDLATVTIADWVDSVIADIEEAGLGDIVI
TH_2893|M.thermoresistible__bu ---------------------PDGTLARDAHVVRDALKQFDQP----AVL
MAB_0554|M.abscessus_ATCC_1997 ----------------GGDVRDAQPVSTERYVDALAEAVRSVG--APVVL
MUL_0147|M.ulcerans_Agy99 ----------------DSDRAPDADYAIETLTSDIRHVLDAIG--RPVVL
.:
Mb0046c|M.bovis_AF2122/97 VGMSLGGLTAI-RLAAMAPDLVGELVLVDVTPS----ALQRHAELTAEQR
Rv0045c|M.tuberculosis_H37Rv VGMSLGGLTAI-RLAAMAPDLVGELVLVDVTPS----ALQRHAELTAEQR
MMAR_0064|M.marinum_M VGMSLGGLTAI-RLGALAPELVDELVLIDVTPS----ALQRHAEMTAEQR
Mvan_4177|M.vanbaalenii_PYR-1 VGHSGGGFDAT-LAADARPDLVHHIVYLAAALPREGRTYPEAMAMRDAEQ
Mflv_2476|M.gilvum_PYR-GCK VGHSGGGFDAT-LAADARPDLVSHITYLAAALPREGRTYPEAMAMRDDDN
MSMEG_6710|M.smegmatis_MC2_155 VAHSAGGGPAS-LAAEKAPELVDHLVYLAAFVP---AARPRFTDYINAPE
MAV_2604|M.avium_104 VGHSMAGVTVPGVVAKLGSSRVREMVLATAFVP------PQGSAIADTLG
TH_2893|M.thermoresistible__bu VGHSYGGAVIT--EASADNDHVAHLIYVCAALPQAGESVSDVLARDPDPQ
MAB_0554|M.abscessus_ATCC_1997 IGHSMGGLHSW-CLAAQRPDLVSALVVEDMAPD--------FVGGTTGPW
MUL_0147|M.ulcerans_Agy99 IGASMGGLTGILVADSAGPDRVTGLVLVDVVPKYEKDGSARIRDFMFTNL
:. * .* . * :
Mb0046c|M.bovis_AF2122/97 GTVALMHG-EREFPSFQAMLDLTIAAAPHRDVKSLR--RGVFHNSRRLDN
Rv0045c|M.tuberculosis_H37Rv GTVALMHG-EREFPSFQAMLDLTIAAAPHRDVKSLR--RGVFHNSRRLDN
MMAR_0064|M.marinum_M GTVALMHG-EREFPSFQAMLDLTVAAAPHREVKALR--RGVFHNSRRLEN
Mvan_4177|M.vanbaalenii_PYR-1 GPAELGDEFDGDVGEMLGYLNFDEDGAMTFADFEGA--WKYFYHDCDEAT
Mflv_2476|M.gilvum_PYR-GCK GPVELGEDFDGDVGEMLGYLHFDDTGAMKFADFDGA--WKYFYHDCDEET
MSMEG_6710|M.smegmatis_MC2_155 NADVVALPIFSDP-ANLGAHRLNPLSSDAIEVDAIR--RAFLTDMPPDAP
MAV_2604|M.avium_104 GPLAVFAR------------RAARIGRPMKIPAPAA--RWAFCNGMTAAQ
TH_2893|M.thermoresistible__bu GDLAPALE--------------VREDGTATMKRDAA--RQALFNDATEEQ
MAB_0554|M.abscessus_ATCC_1997 EPWLYSWP-----------EVFTSAGEFTARFGEIA--GRYFREAFDRVD
MUL_0147|M.ulcerans_Agy99 HGFATLEEAADAVATYLPHRTKPRSPEGLKKNLRLRDGRWYWHWDPAMMT
Mb0046c|M.bovis_AF2122/97 GNWVWRYDAIRTFGDFAGLWDDVDALSAPITLVRGGSSGFVTDQDTAELH
Rv0045c|M.tuberculosis_H37Rv GNWVWRYDAIRTFGDFAGLWDDVDALSAPITLVRGGSSGFVTDQDTAELH
MMAR_0064|M.marinum_M GNWAWRYDAIRAFPDFAVLWDDVDALAAPVTLVRGGKSGFVSDEDIAELR
Mvan_4177|M.vanbaalenii_PYR-1 ARWAFERLGPERFGDTT-----VTPVSVPDFWAADLPRSFIVCEQDRSMP
Mflv_2476|M.gilvum_PYR-GCK ARWAFERLGPERFGDTT-----VTPVSVPNFWAADLPRSFIVCEQDQAMP
MSMEG_6710|M.smegmatis_MC2_155 EGWRHLLHPDEPYASLS------APVPVTPRRWGRIPRTYIRLDGDRALA
MAV_2604|M.avium_104 RRLTMSKLQAESARVPG------EPVDR-SGLPADVPRTWILTTRDRALS
TH_2893|M.thermoresistible__bu FESVVDKLGPHAMGTLS--------EPVTGLGWQQHPATYVIALRDQMFS
MAB_0554|M.abscessus_ATCC_1997 DGWRLHGPIEEWISTAAEWG-----VRDFWDQWRAVQCPALLLEADDTVT
MUL_0147|M.ulcerans_Agy99 APGDDPELRTENFERAAMN------LTIPILLIRGKLSDVVTSEGVQDFL
. : .
Mb0046c|M.bovis_AF2122/97 RRATHFRG------------VHIVEKSGHSVQSDQPRALIEIVRGVLDTR
Rv0045c|M.tuberculosis_H37Rv RRATHFRG------------VHIVEKSGHSVQSDQPRALIEIVRGVLDTR
MMAR_0064|M.marinum_M GRAKGFRG------------AQTVENSGHSVQSDQPRVLVEILRGVLGGR
Mvan_4177|M.vanbaalenii_PYR-1 RWLADTVARRLG-------VEQLTIDASHSPFLSRPRELAELLVRATTTT
Mflv_2476|M.gilvum_PYR-GCK RWLADTVARRLG-------VDQLTIDASHSPFLSRPREFADLLVHATTTT
MSMEG_6710|M.smegmatis_MC2_155 PTTQNLMIAEADRLTPDNPFGVRSLPGDHSPMVHRPGELADLLAGI----
MAV_2604|M.avium_104 VASQHASIAALG-----GVETVIPVDACHEVMFSHPERLAQILIERCRLR
TH_2893|M.thermoresistible__bu VALQEEFASHVG--------TVAKIDTGHGPMATRPAELAEIIATAAR--
MAB_0554|M.abscessus_ATCC_1997 PAGQMQKMSEIG----RRTTYFKIAGSGHLMHDDSPKLYRSAVSDFLAAP
MUL_0147|M.ulcerans_Agy99 DKVPHAEFVELS-------------NAGHTAAGDDNDAFTEVVVDFVKRR
* . :
Mb0046c|M.bovis_AF2122/97 ---------
Rv0045c|M.tuberculosis_H37Rv ---------
MMAR_0064|M.marinum_M ---------
Mvan_4177|M.vanbaalenii_PYR-1 PVSPLVPH-
Mflv_2476|M.gilvum_PYR-GCK PVAPLRPL-
MSMEG_6710|M.smegmatis_MC2_155 ---------
MAV_2604|M.avium_104 GVGIR----
TH_2893|M.thermoresistible__bu ---------
MAB_0554|M.abscessus_ATCC_1997 GAPGASVVA
MUL_0147|M.ulcerans_Agy99 AATG-----