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SEPLLRAVGVRKSYGHTEVLRGIDLEVRRGEVVCLLGPSGAGKSTFLRCLNHLETIDAGQVWVDGEPIGF ALRDGKLHELRERDVARQRRDIGMVFQRFNLFGHRTALENIIEGPVRVRGVSPDVARREGMELLERVGLA DRADAFPAQLSGGQQQRVAIARSLAMKPKLMLFDEPTSALDPELVGEVLAVMNSLAREGMTMVVVTHEIG FAAEAADEVVFMADGTVVETGPPDRVLKDPEHERTRQFLARVLA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6593 | - | - | 100% (255) | ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_3237 | - | 7e-92 | 64.00% (250) | ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_0178 | - | 8e-85 | 59.92% (252) | ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2593 | glnQ | 6e-35 | 41.67% (216) | glutamine-transport ATP-binding protein ABC transporter GlnQ |
| M. gilvum PYR-GCK | Mflv_3581 | - | 9e-95 | 65.61% (253) | ABC transporter related |
| M. tuberculosis H37Rv | Rv2564 | glnQ | 6e-35 | 41.67% (216) | glutamine-transport ATP-binding protein ABC transporter GlnQ |
| M. leprae Br4923 | MLBr_01122 | - | 7e-33 | 32.14% (252) | putative ABC transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_4237c | - | 1e-78 | 58.94% (246) | amino acid ABC transporter ATP-binding protein |
| M. marinum M | MMAR_0060 | - | 1e-62 | 51.00% (249) | glutamine ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_0058 | - | 6e-61 | 49.23% (260) | ABC transporter, ATP-binding protein |
| M. thermoresistible (build 8) | TH_1784 | - | 1e-77 | 56.97% (251) | ABC transporter, ATP-binding protein GluA |
| M. ulcerans Agy99 | MUL_0674 | - | 7e-37 | 42.04% (226) | ABC transporter, ATP-binding protein |
| M. vanbaalenii PYR-1 | Mvan_2834 | - | 3e-93 | 64.82% (253) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2593|M.bovis_AF2122/97 --------------------------------------------------
Rv2564|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0674|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6593|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01122|M.leprae_Br4923 MSPLLEVTDLAVTFETNGEPVTAVRGISYRINAGEVVAMVGESGSGKSAA
Mb2593|M.bovis_AF2122/97 --------------------------------------------------
Rv2564|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0674|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6593|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01122|M.leprae_Br4923 AMAVVGLLPEYAQVRGSVRLHNTELVGLADKTMSRFRGKAIGTVFQDPMS
Mb2593|M.bovis_AF2122/97 --------------------------------------------------
Rv2564|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0674|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6593|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01122|M.leprae_Br4923 ALTPVYTVGDQITEAIKVHQPRVGKKAAHRRAVELLELVGITQPDRRARA
Mb2593|M.bovis_AF2122/97 --------------------------------------------------
Rv2564|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0674|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6593|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01122|M.leprae_Br4923 FPHELSGGERQRVVIATAIANDPDLLICDEPTTALDVTVQAQILEVLKTA
Mb2593|M.bovis_AF2122/97 --------------------------------------------------
Rv2564|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0674|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6593|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01122|M.leprae_Br4923 RDVTGAGVLIITHDLGVVTEFADQALVMYAGRVVESAQVSTLYRERQMPY
Mb2593|M.bovis_AF2122/97 --------------------------------------------------
Rv2564|M.tuberculosis_H37Rv --------------------------------------------------
MUL_0674|M.ulcerans_Agy99 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6593|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01122|M.leprae_Br4923 TVGLLGSVPRLDATQGTRLVPIPGAPPSLAGLQQECPFAPRCPLVVDECR
Mb2593|M.bovis_AF2122/97 ----------------------------------------------MGGL
Rv2564|M.tuberculosis_H37Rv ----------------------------------------------MGGL
MUL_0674|M.ulcerans_Agy99 ------------------------------------MTRAQAPTSPRGGV
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------MTTSENSAHPMV
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------MTADAVSAKPMV
MSMEG_6593|M.smegmatis_MC2_155 --------------------------------------------MSEPLL
MAB_4237c|M.abscessus_ATCC_199 ----------------------------------------------MSTI
MMAR_0060|M.marinum_M -------------------------------------MTRQDAGRQPVCL
MAV_0058|M.avium_104 -------------------------------------MS-NPASRASVSL
TH_1784|M.thermoresistible__bu -----------------------------MDSAGADVAVADPAAEAVPMI
MLBr_01122|M.leprae_Br4923 LREPELVEVRAGHRTACIRTDQVSGRSAADIYGINTDTRTSATSDSSVVV
:
Mb2593|M.bovis_AF2122/97 TISDLVVEYSSGG--------YAVRPIDGLSLDVAPGSLVILLGPSGCGK
Rv2564|M.tuberculosis_H37Rv TISDLVVEYSSGG--------YAVRPIDGLSLDVAPGSLVILLGPSGCGK
MUL_0674|M.ulcerans_Agy99 SLHGVDKTFGTAA--------ASVHALRRIDLDIEPGELVAIVGESGSGK
Mflv_3581|M.gilvum_PYR-GCK KAELVCKDFG------------ALKVLKGITLEVQKGQVLVLVGPSGSGK
Mvan_2834|M.vanbaalenii_PYR-1 KAELVCKDFG------------ALKVLKGITLEVQKGQVLVLVGPSGSGK
MSMEG_6593|M.smegmatis_MC2_155 RAVGVRKSYG------------HTEVLRGIDLEVRRGEVVCLLGPSGAGK
MAB_4237c|M.abscessus_ATCC_199 EVRGVRKSYG------------QVTALRDVNLTVHQGEVTVIIGPSGSGK
MMAR_0060|M.marinum_M AARSIHQTLG------------GSVVLRGVDLEVPAGTTAAVIGPSGSGK
MAV_0058|M.avium_104 ACKDIHQTLN------------GNAVLRGVDLDTPAGSTVAVIGPSGSGK
TH_1784|M.thermoresistible__bu SMRGVNKYFG------------SLHVLRDINLDVARGQVVVVLGPSGSGK
MLBr_01122|M.leprae_Br4923 RVRDLVKTYRLTKGVGLRRAIGEIRAVNGVSFELQQGRTLGIVGESGSGK
: : : : * ::* **.**
Mb2593|M.bovis_AF2122/97 TTLLSCLGGILRPKSGSIKFDDVD---------ITTLEGAALAKYRRDKV
Rv2564|M.tuberculosis_H37Rv TTLLSCLGGILRPKSGSIKFDDVD---------ITTLEGAALAKYRRDKV
MUL_0674|M.ulcerans_Agy99 TTLLNVIGGIEEANSGSINVAGQD---------ISGCRPRALSKFRRDHV
Mflv_3581|M.gilvum_PYR-GCK STLLRCINHLETVSAGRLYVDGTLVGYHERGGKLYEMKPRDVARQRRD-V
Mvan_2834|M.vanbaalenii_PYR-1 STFLRCINHLETVSAGRLYVDGALVGYNERGGKLHEMKPRDVAKQRRD-V
MSMEG_6593|M.smegmatis_MC2_155 STFLRCLNHLETIDAGQVWVDGEPIGFALRDGKLHELRERDVARQRRD-I
MAB_4237c|M.abscessus_ATCC_199 STLLRALNHLEKVDAGTIRIDGELIGYRQRGSVLYELPERAILRQRSQ-V
MMAR_0060|M.marinum_M STLLRTLNRLHEPDSGDILLDGR--------SVLRD----NPNDLRQR-I
MAV_0058|M.avium_104 STLLRTLNRLYEPDRGDILLDGR--------SVLHD----DPDQLRQR-I
TH_1784|M.thermoresistible__bu STLCRTLNRLEPIDSGAISIDGV--------ALPAEG--RELARLRAD-V
MLBr_01122|M.leprae_Br4923 STTLHEILRLAVPQSGSIEVLGID---------VATLNRASRRSMRRNIQ
:* : : . * : . . *
Mb2593|M.bovis_AF2122/97 GIVFQAFNLVSSLTALENVMVP-LRAAGVSRAAARKRAEDLLIRVNLG-E
Rv2564|M.tuberculosis_H37Rv GIVFQAFNLVSSLTALENVMVP-LRAAGVSRAAARKRAEDLLIRVNLG-E
MUL_0674|M.ulcerans_Agy99 GFIFQFFNLIPTLTAKENVEVI-VELTGRG---DRRRATELLDAVELA-D
Mflv_3581|M.gilvum_PYR-GCK GMVFQHFNLFPHRTALGNVVEAPIQVKGVKKDEAVTRGRELLAQVGLA-D
Mvan_2834|M.vanbaalenii_PYR-1 GMVFQHFNLFPHRTALGNVVEAPIQVKGVRKAQAIEKGKELLAQVGLA-D
MSMEG_6593|M.smegmatis_MC2_155 GMVFQRFNLFGHRTALENIIEGPVRVRGVSPDVARREGMELLERVGLA-D
MAB_4237c|M.abscessus_ATCC_199 GFVFQNFNLFPHLTVLENVIEAPLAARRAPRAELEAEATRLLERVGVA-D
MMAR_0060|M.marinum_M GMVFQHFNLFPHRNVVDNVTLAPRKLRGLSNEEARMLALDQLDRVGLK-H
MAV_0058|M.avium_104 GMVFQHFNLFPHRTVLDNVALAPRKLRRLPAEAARELALTQLDRVGLK-H
TH_1784|M.thermoresistible__bu GMVFQQFNLFAHKTIVDNVALGPMKVRKTPREQARAEAMALLERVGVA-D
MLBr_01122|M.leprae_Br4923 VVFQDPVASLDPRLPVFELIAEPLHANGFSKNYTQMRVAELLDIVGLRRD
.. : . . :: * * : .
Mb2593|M.bovis_AF2122/97 RMKHRPGDMSGGQQQRVAVARAIALDPQLILADEPTAHLDFIQVEEVLRL
Rv2564|M.tuberculosis_H37Rv RMKHRPGDMSGGQQQRVAVARAIALDPQLILADEPTAHLDFIQVEEVLRL
MUL_0674|M.ulcerans_Agy99 RAGSFPGQLSGGQQQRVAIARALITNPDLLLADEPMGALDVATGRRVLEL
Mflv_3581|M.gilvum_PYR-GCK KADAYPAQLSGGQQQRVAIARALAMDPKLMLFDEPTSALDPELVGEVLAV
Mvan_2834|M.vanbaalenii_PYR-1 KAGAYPAQLSGGQQQRVAIARALAMDPKLMLFDEPTSALDPELVGEVLGV
MSMEG_6593|M.smegmatis_MC2_155 RADAFPAQLSGGQQQRVAIARSLAMKPKLMLFDEPTSALDPELVGEVLAV
MAB_4237c|M.abscessus_ATCC_199 KAAQYPRRLSGGQQQRVAIARALALRPKVILFDEPTSALDPELVTEVLDV
MMAR_0060|M.marinum_M KANARPDMLSGGQQQRVAIARALAMAPQVMFFDEATSALDPEMVKGILAL
MAV_0058|M.avium_104 KAGARPATLSGGQQQRVAIARALAMSPQVMFFDEATSALDPEMVKGILQL
TH_1784|M.thermoresistible__bu QADKYPAQLSGGQQQRVAIARSLAMNPKVMLFDEPTSALDPEMINEVLAV
MLBr_01122|M.leprae_Br4923 DATRYPTEFSGGQKQRIGIARALALQPKILAFDEPVSALDVSIQAGIINL
* :****:**:.:**:: *.:: **. . ** :: :
Mb2593|M.bovis_AF2122/97 IRSLAQ-GDRVVVVATHDSRMLPLADRVLELMPAQVSPNQPPETVHVKAG
Rv2564|M.tuberculosis_H37Rv IRSLAQ-GDRVVVVATHDSRMLPLADRVLELMPAQVSPNQPPETVHVKAG
MUL_0674|M.ulcerans_Agy99 LQQTNR-SGLGVIMVTHNRAAADVADPIIQMR-----------------D
Mflv_3581|M.gilvum_PYR-GCK MKKLAA-QGMTMVVVTHEMGFAREVADELVFMD----------------E
Mvan_2834|M.vanbaalenii_PYR-1 MKKLAA-QGMTMVVVTHEMGFAREVADELVFMD----------------A
MSMEG_6593|M.smegmatis_MC2_155 MNSLAR-EGMTMVVVTHEIGFAAEAADEVVFMA----------------D
MAB_4237c|M.abscessus_ATCC_199 IAQLAR-DGATLVIVTHEIGLAREIADTVVFMD----------------R
MMAR_0060|M.marinum_M IADLGA-DGMTMVVVTHEMGFARSTSDAVVFMD----------------H
MAV_0058|M.avium_104 IADLGA-EGMTMVVVTHEMGFARSASDAVIFMD----------------H
TH_1784|M.thermoresistible__bu MSALAA-DGMTMLVVTHEMGFARRASDRVVFMS----------------D
MLBr_01122|M.leprae_Br4923 LLDLQDRLGLSYLFVSHDLSVIKHLAHQVAVML----------------A
: . :..:*: : .
Mb2593|M.bovis_AF2122/97 EVLFEQSTMGDLIYVVSEGEFEIVRELADGGEELVKTAAPGDYFGEIGVL
Rv2564|M.tuberculosis_H37Rv EVLFEQSTMGDLIYVVSEGEFEIVRELADGGEELVKTAAPGDYFGEIGVL
MUL_0674|M.ulcerans_Agy99 GAIVEQR----------------------------RNSAP----------
Mflv_3581|M.gilvum_PYR-GCK GVVVERG-------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1 GVVVERG-------------------------------------------
MSMEG_6593|M.smegmatis_MC2_155 GTVVETG-------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 GAIVEQG-------------------------------------------
MMAR_0060|M.marinum_M GTVVEAG-------------------------------------------
MAV_0058|M.avium_104 GKVVESG-------------------------------------------
TH_1784|M.thermoresistible__bu GAIVEDA-------------------------------------------
MLBr_01122|M.leprae_Br4923 GTIVEQG-------------------------------------------
:.*
Mb2593|M.bovis_AF2122/97 FHLPRSATVRARSDATAVGYTAQAFRERLGVTRVADLIEHRELASE
Rv2564|M.tuberculosis_H37Rv FHLPRSATVRARSDATAVGYTAQAFRERLGVTRVADLIEHRELASE
MUL_0674|M.ulcerans_Agy99 ------------AEASSVRW--------------------------
Mflv_3581|M.gilvum_PYR-GCK ---NPREVMSNPQHERTKAFLSKVM---------------------
Mvan_2834|M.vanbaalenii_PYR-1 ---APREVMANPQHERTKAFLSKVM---------------------
MSMEG_6593|M.smegmatis_MC2_155 ---PPDRVLKDPEHERTRQFLARVLA--------------------
MAB_4237c|M.abscessus_ATCC_199 ---PPKEVLDSPSHPRTASFLSKVLS--------------------
MMAR_0060|M.marinum_M ---PPEQLFEAARTERLQRFLAQVL---------------------
MAV_0058|M.avium_104 ---PPEQIFEAAETERLQRFLSQVL---------------------
TH_1784|M.thermoresistible__bu ---EPARFFEDPQTDRARDFLGKILHH-------------------
MLBr_01122|M.leprae_Br4923 ---DSHDVFRNPQHDYTRRLLGAIPRPEVG----------------