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SNPASRASVSLACKDIHQTLNGNAVLRGVDLDTPAGSTVAVIGPSGSGKSTLLRTLNRLYEPDRGDILLD GRSVLHDDPDQLRQRIGMVFQHFNLFPHRTVLDNVALAPRKLRRLPAEAARELALTQLDRVGLKHKAGAR PATLSGGQQQRVAIARALAMSPQVMFFDEATSALDPEMVKGILQLIADLGAEGMTMVVVTHEMGFARSAS DAVIFMDHGKVVESGPPEQIFEAAETERLQRFLSQVL*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_0058 | - | - | 100% (248) | ABC transporter, ATP-binding protein |
M. avium 104 | MAV_1785 | - | 1e-38 | 37.60% (242) | sulfate/thiosulfate import ATP-binding protein CysA |
M. avium 104 | MAV_0318 | - | 1e-35 | 39.91% (228) | amino acid ABC transporter, ATP-binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb2419c | cysA1 | 7e-36 | 39.73% (219) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
M. gilvum PYR-GCK | Mflv_0857 | - | 1e-106 | 78.01% (241) | ABC transporter related |
M. tuberculosis H37Rv | Rv0933 | pstB | 3e-38 | 37.10% (248) | phosphate ABC transporter ATP-binding protein |
M. leprae Br4923 | MLBr_01892 | - | 1e-31 | 32.47% (231) | ABC transporter ATP-binding protein |
M. abscessus ATCC 19977 | MAB_3050 | - | 6e-63 | 51.67% (240) | putative glutamate ABC transporter, ATP-binding protein |
M. marinum M | MMAR_0060 | - | 1e-111 | 82.79% (244) | glutamine ABC transporter, ATP-binding protein |
M. smegmatis MC2 155 | MSMEG_6911 | - | 1e-104 | 77.50% (240) | ABC transporter, ATP-binding protein GluA |
M. thermoresistible (build 8) | TH_0514 | - | 1e-109 | 82.08% (240) | ABC transporter, ATP-binding protein GluA |
M. ulcerans Agy99 | MUL_3658 | cysA1 | 7e-39 | 38.66% (238) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
M. vanbaalenii PYR-1 | Mvan_6048 | - | 1e-112 | 83.33% (240) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment Mb2419c|M.bovis_AF2122/97 -----------MT------YAIVVADATKRYGDFVALDHVDFVVPTGSLT MUL_3658|M.ulcerans_Agy99 -----------MTGPGTGGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLT MAV_0058|M.avium_104 ---------MS-NPASRASVSLACKDIHQTLNGNAVLRGVDLDTPAGSTV MMAR_0060|M.marinum_M ---------MTRQDAGRQPVCLAARSIHQTLGGSVVLRGVDLEVPAGTTA MSMEG_6911|M.smegmatis_MC2_155 -------------MPAPDAVSLTATNIHLAFGPNKVLRGVDLDVPAGTTT TH_0514|M.thermoresistible__bu -------------MTQPKAVSLAATDIHLAFGPNKVLRGVDLEVPAGTTA Mflv_0857|M.gilvum_PYR-GCK -------------MTS--AVSLAATDIHLSFGTTAVLRGVDLDVAAGSST Mvan_6048|M.vanbaalenii_PYR-1 -------------MTT--AVSLTAKDIHLSFGKSAVLRGVDLDVAAGSST MAB_3050|M.abscessus_ATCC_1997 MPVSTDTSTSGESSSAPSVPMIALEHVNKHFGDLHVLKDITLEIPRGQVV Rv0933|M.tuberculosis_H37Rv MACERLGGQSGAADVDAAAPAMAAVNLTLGFAGKTVLDQVSMGFPARAVT MLBr_01892|M.leprae_Br4923 ---------------MPMGVAIEVKGLTKSFGSSRIWEDVTLDIPAGEVS : : : . Mb2419c|M.bovis_AF2122/97 ALLGPSGSGKSTLLRTIAGLDQPDT-----GTITINGRDVTRVPP----- MUL_3658|M.ulcerans_Agy99 ALLGPSGSGKSTLLRTIAGLDQPDS-----GNITINGRDVTRVPP----- MAV_0058|M.avium_104 AVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLHDDP---DQ MMAR_0060|M.marinum_M AVIGPSGSGKSTLLRTLNRLHEPDS-----GDILLDGRSVLRDNP---ND MSMEG_6911|M.smegmatis_MC2_155 AVIGPSGSGKSTLLRTLNRLYEPDE-----GDVLLDGRSVLRDNP---DQ TH_0514|M.thermoresistible__bu AVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLRDNP---DQ Mflv_0857|M.gilvum_PYR-GCK AVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLRDDP---NA Mvan_6048|M.vanbaalenii_PYR-1 AVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLGDNP---DQ MAB_3050|M.abscessus_ATCC_1997 VILGPSGSGKSTLCRTINRLEPIDG-----GTIRIDG-AILPEEGRALAS Rv0933|M.tuberculosis_H37Rv SLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLGGRSIFNYRD--VLE MLBr_01892|M.leprae_Br4923 VLLGPSGTGKSVFLKSLIGLLRPER-----GSILIDGTDIIECSAKELYE ::**:*:**:.: ::: : * : :.* : Mb2419c|M.bovis_AF2122/97 QRRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKVDNLLQVV MUL_3658|M.ulcerans_Agy99 QRRGIGFVFQHYAAFKHLTVRDNVAYG-LKIRKRPKAEIRDKVDNLLEVV MAV_0058|M.avium_104 LRQRIGMVFQHFNLFPHRTVLDNVALAPRKLRRLPAEAARELALTQLDRV MMAR_0060|M.marinum_M LRQRIGMVFQHFNLFPHRNVVDNVTLAPRKLRGLSNEEARMLALDQLDRV MSMEG_6911|M.smegmatis_MC2_155 LRQRIGMVFQQFNLFPHRSVLDNVTLGPRRLKGLGADDARELGLAQLDRV TH_0514|M.thermoresistible__bu LRQRIGMVFQHFNLFPHRTVLDNVTLAPRKLKRLSRDEARELGLRQLERV Mflv_0857|M.gilvum_PYR-GCK LRQRIGMVFQQFQLFPHKSVLDNVTLGPRKLKKMSADAARELGMAQLDRV Mvan_6048|M.vanbaalenii_PYR-1 LRQRIGMVFQHFQLFPHRTVLDNVTLAPRKLKRLSGDEARELGMAQLDRV MAB_3050|M.abscessus_ATCC_1997 LRAEVGMVFQSFNLFSHKTILDNVTLAPIKVRKHNKETARKRAIELLERV Rv0933|M.tuberculosis_H37Rv FRRRVGMLFQRPNPFP-MSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEV MLBr_01892|M.leprae_Br4923 IRTLFGVLFQDGALFGSMNLYDNTAFPLREHTKKKESEIRDIVMEKLQLV * .*.:** * .: **. : * * Mb2419c|M.bovis_AF2122/97 G----LSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK MUL_3658|M.ulcerans_Agy99 G----LSGFHGRYPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK MAV_0058|M.avium_104 G----LKHKAGARPATLSGGQQQRVAIARALAMSPQVMFFDEATSALDPE MMAR_0060|M.marinum_M G----LKHKANARPDMLSGGQQQRVAIARALAMAPQVMFFDEATSALDPE MSMEG_6911|M.smegmatis_MC2_155 G----LRHKADVRPGTLSGGQQQRVAIARALAMAPQVMFFDEATSALDPE TH_0514|M.thermoresistible__bu G----LRHKAEVRPTTLSGGQQQRVAIARALAMDPQVMFFDEATSALDPE Mflv_0857|M.gilvum_PYR-GCK G----LRNKADVRPSTLSGGQQQRVAIARALAMSPQVMFFDEATSALDPE Mvan_6048|M.vanbaalenii_PYR-1 G----LRNKADARPATLSGGQQQRVAIARALAMSPQVMFFDEATSALDPE MAB_3050|M.abscessus_ATCC_1997 G----IASQKDKYPAQLSGGQQQRVAIARSLAMGPKVMLFDEPTSALDPE Rv0933|M.tuberculosis_H37Rv GLWDAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPT MLBr_01892|M.leprae_Br4923 G----LGGDEKKFPGEISGGMRKRAGLARALVLDPQIILCDEPDSGLDPV * : * :*** :: :**:*.: *:::: **. ..**. Mb2419c|M.bovis_AF2122/97 VREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGS MUL_3658|M.ulcerans_Agy99 VREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGS MAV_0058|M.avium_104 MVKGILQLIADLGAEG-MTMVVVTHEMGFARSASDAVIFMDHGKVVESGP MMAR_0060|M.marinum_M MVKGILALIADLGADG-MTMVVVTHEMGFARSTSDAVVFMDHGTVVEAGP MSMEG_6911|M.smegmatis_MC2_155 LVKGILSLMADLAADG-MTIVAVTHEMGFARSTANTVVFMDQGRVVESGE TH_0514|M.thermoresistible__bu LVKGILALIADLAESG-MTMVVVTHEMGFARSTADTVVFMDHGQVVESGP Mflv_0857|M.gilvum_PYR-GCK LVKGVLALIAELASDG-MTMVVVTHEMGFARSTADQLVFMDHGQVVETGP Mvan_6048|M.vanbaalenii_PYR-1 LVKGVLELIADLGAEG-MTMVVVTHEMGFARSSADTVVFMDHGQVVETGP MAB_3050|M.abscessus_ATCC_1997 MVNEVLDVMVSLAKEG-MTMLVVTHEMGFARKAADRIIFMADGAIVEDSD Rv0933|M.tuberculosis_H37Rv TTEKIEEFIRSLADRL--TVIIVTHNLAQAARISDRAALFFDGRLVEEGP MLBr_01892|M.leprae_Br4923 RTAYLSQLIMDINAQIDATILIVTHNVNIARTVPDNMGMLFRKHLVMFGP : : : * : ***: * .: .: : . Mb2419c|M.bovis_AF2122/97 PTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTA MUL_3658|M.ulcerans_Agy99 PTEVYDAPTNAFVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTG MAV_0058|M.avium_104 PEQIFEAAETERLQRFLSQVL----------------------------- MMAR_0060|M.marinum_M PEQLFEAARTERLQRFLAQVL----------------------------- MSMEG_6911|M.smegmatis_MC2_155 PDQLFEAAETDRLRRFLSQVL----------------------------- TH_0514|M.thermoresistible__bu PQQIFESAATERLRRFLSQVL----------------------------- Mflv_0857|M.gilvum_PYR-GCK PEQLFEAAETDRLRRFLSQVL----------------------------- Mvan_6048|M.vanbaalenii_PYR-1 PEQLFEAAETDRLRRFLSQVL----------------------------- MAB_3050|M.abscessus_ATCC_1997 PESFFTNPKSERAKDFLGKILGH--------------------------- Rv0933|M.tuberculosis_H37Rv TEQLFSSPKHAETARYVAGLSGDVKDAKRGN------------------- MLBr_01892|M.leprae_Br4923 REVLLTSDEPVVRQFLNGRRIGPIGMSEEKDESTMAEEAALLEAGHYAGG . . Mb2419c|M.bovis_AF2122/97 GSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREG MUL_3658|M.ulcerans_Agy99 ESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEG MAV_0058|M.avium_104 -------------------------------------------------- MMAR_0060|M.marinum_M -------------------------------------------------- MSMEG_6911|M.smegmatis_MC2_155 -------------------------------------------------- TH_0514|M.thermoresistible__bu -------------------------------------------------- Mflv_0857|M.gilvum_PYR-GCK -------------------------------------------------- Mvan_6048|M.vanbaalenii_PYR-1 -------------------------------------------------- MAB_3050|M.abscessus_ATCC_1997 -------------------------------------------------- Rv0933|M.tuberculosis_H37Rv -------------------------------------------------- MLBr_01892|M.leprae_Br4923 AEEVEGVPPQITVTPGMPKRKAVARRQARVRAMLPTLPKGAQAAILDDLE Mb2419c|M.bovis_AF2122/97 DTVYVRATRVPPIAGGVSGVDDAGVERVKVTST------ MUL_3658|M.ulcerans_Agy99 DTVYVRATRVPPIAGAAPAVPDDGAGSTPRAAQIGVGGQ MAV_0058|M.avium_104 --------------------------------------- MMAR_0060|M.marinum_M --------------------------------------- MSMEG_6911|M.smegmatis_MC2_155 --------------------------------------- TH_0514|M.thermoresistible__bu --------------------------------------- Mflv_0857|M.gilvum_PYR-GCK --------------------------------------- Mvan_6048|M.vanbaalenii_PYR-1 --------------------------------------- MAB_3050|M.abscessus_ATCC_1997 --------------------------------------- Rv0933|M.tuberculosis_H37Rv --------------------------------------- MLBr_01892|M.leprae_Br4923 GAHNYQAHEFGD---------------------------