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TRQDAGRQPVCLAARSIHQTLGGSVVLRGVDLEVPAGTTAAVIGPSGSGKSTLLRTLNRLHEPDSGDILL DGRSVLRDNPNDLRQRIGMVFQHFNLFPHRNVVDNVTLAPRKLRGLSNEEARMLALDQLDRVGLKHKANA RPDMLSGGQQQRVAIARALAMAPQVMFFDEATSALDPEMVKGILALIADLGADGMTMVVVTHEMGFARST SDAVVFMDHGTVVEAGPPEQLFEAARTERLQRFLAQVL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0060 | - | - | 100% (249) | glutamine ABC transporter, ATP-binding protein |
| M. marinum M | MMAR_3715 | cysA1 | 2e-38 | 39.24% (237) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. marinum M | MMAR_5301 | proV | 5e-36 | 40.35% (228) | osmoprotectant transport ATP-binding protein ABC transporter |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2419c | cysA1 | 1e-36 | 39.21% (227) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. gilvum PYR-GCK | Mflv_0857 | - | 1e-102 | 76.99% (239) | ABC transporter related |
| M. tuberculosis H37Rv | Rv0933 | pstB | 3e-38 | 39.59% (245) | phosphate ABC transporter ATP-binding protein |
| M. leprae Br4923 | MLBr_01892 | - | 5e-31 | 32.74% (226) | ABC transporter ATP-binding protein |
| M. abscessus ATCC 19977 | MAB_3050 | - | 2e-62 | 49.79% (239) | putative glutamate ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_0058 | - | 1e-111 | 82.79% (244) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_6911 | - | 1e-103 | 77.82% (239) | ABC transporter, ATP-binding protein GluA |
| M. thermoresistible (build 8) | TH_0514 | - | 1e-107 | 82.01% (239) | ABC transporter, ATP-binding protein GluA |
| M. ulcerans Agy99 | MUL_3658 | cysA1 | 3e-39 | 39.66% (237) | sulfate-transport ATP-binding protein ABC transporter CysA1 |
| M. vanbaalenii PYR-1 | Mvan_6048 | - | 1e-105 | 79.50% (239) | ABC transporter-related protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2419c|M.bovis_AF2122/97 -----------MT------YAIVVADATKRYGDFVALDHVDFVVPTGSLT
MUL_3658|M.ulcerans_Agy99 -----------MTGPGTGGHAIVVRDAFKQYGDFVALDHVDFVVPAGSLT
MMAR_0060|M.marinum_M ---------MTRQDAGRQPVCLAARSIHQTLGGSVVLRGVDLEVPAGTTA
MAV_0058|M.avium_104 ---------MS-NPASRASVSLACKDIHQTLNGNAVLRGVDLDTPAGSTV
MSMEG_6911|M.smegmatis_MC2_155 -------------MPAPDAVSLTATNIHLAFGPNKVLRGVDLDVPAGTTT
TH_0514|M.thermoresistible__bu -------------MTQPKAVSLAATDIHLAFGPNKVLRGVDLEVPAGTTA
Mflv_0857|M.gilvum_PYR-GCK -------------MTS--AVSLAATDIHLSFGTTAVLRGVDLDVAAGSST
Mvan_6048|M.vanbaalenii_PYR-1 -------------MTT--AVSLTAKDIHLSFGKSAVLRGVDLDVAAGSST
MAB_3050|M.abscessus_ATCC_1997 MPVSTDTSTSGESSSAPSVPMIALEHVNKHFGDLHVLKDITLEIPRGQVV
Rv0933|M.tuberculosis_H37Rv MACERLGGQSGAADVDAAAPAMAAVNLTLGFAGKTVLDQVSMGFPARAVT
MLBr_01892|M.leprae_Br4923 ---------------MPMGVAIEVKGLTKSFGSSRIWEDVTLDIPAGEVS
: : : .
Mb2419c|M.bovis_AF2122/97 ALLGPSGSGKSTLLRTIAGLDQPDT-----GTITINGRDVTRVPP-----
MUL_3658|M.ulcerans_Agy99 ALLGPSGSGKSTLLRTIAGLDQPDS-----GNITINGRDVTRVPP-----
MMAR_0060|M.marinum_M AVIGPSGSGKSTLLRTLNRLHEPDS-----GDILLDGRSVLRDNP---ND
MAV_0058|M.avium_104 AVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLHDDP---DQ
MSMEG_6911|M.smegmatis_MC2_155 AVIGPSGSGKSTLLRTLNRLYEPDE-----GDVLLDGRSVLRDNP---DQ
TH_0514|M.thermoresistible__bu AVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLRDNP---DQ
Mflv_0857|M.gilvum_PYR-GCK AVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLRDDP---NA
Mvan_6048|M.vanbaalenii_PYR-1 AVIGPSGSGKSTLLRTLNRLYEPDR-----GDILLDGRSVLGDNP---DQ
MAB_3050|M.abscessus_ATCC_1997 VILGPSGSGKSTLCRTINRLEPIDG-----GTIRIDG-AILPEEGRALAS
Rv0933|M.tuberculosis_H37Rv SLMGPTGSGKTTFLRTLNRMNDKVSGYRYSGDVLLGGRSIFNYRD--VLE
MLBr_01892|M.leprae_Br4923 VLLGPSGTGKSVFLKSLIGLLRPER-----GSILIDGTDIIECSAKELYE
::**:*:**:.: ::: : * : :.* :
Mb2419c|M.bovis_AF2122/97 QRRGIGFVFQHYAAFKHLTVRDNVAFG-LKIRKRPKAEIKAKVDNLLQVV
MUL_3658|M.ulcerans_Agy99 QRRGIGFVFQHYAAFKHLTVRDNVAYG-LKIRKRPKAEIRDKVDNLLEVV
MMAR_0060|M.marinum_M LRQRIGMVFQHFNLFPHRNVVDNVTLAPRKLRGLSNEEARMLALDQLDRV
MAV_0058|M.avium_104 LRQRIGMVFQHFNLFPHRTVLDNVALAPRKLRRLPAEAARELALTQLDRV
MSMEG_6911|M.smegmatis_MC2_155 LRQRIGMVFQQFNLFPHRSVLDNVTLGPRRLKGLGADDARELGLAQLDRV
TH_0514|M.thermoresistible__bu LRQRIGMVFQHFNLFPHRTVLDNVTLAPRKLKRLSRDEARELGLRQLERV
Mflv_0857|M.gilvum_PYR-GCK LRQRIGMVFQQFQLFPHKSVLDNVTLGPRKLKKMSADAARELGMAQLDRV
Mvan_6048|M.vanbaalenii_PYR-1 LRQRIGMVFQHFQLFPHRTVLDNVTLAPRKLKRLSGDEARELGMAQLDRV
MAB_3050|M.abscessus_ATCC_1997 LRAEVGMVFQSFNLFSHKTILDNVTLAPIKVRKHNKETARKRAIELLERV
Rv0933|M.tuberculosis_H37Rv FRRRVGMLFQRPNPFP-MSIMDNVLAGVRAHKLVPRKEFRGVAQARLTEV
MLBr_01892|M.leprae_Br4923 IRTLFGVLFQDGALFGSMNLYDNTAFPLREHTKKKESEIRDIVMEKLQLV
* .*.:** * .: **. : * *
Mb2419c|M.bovis_AF2122/97 G----LSGFQSRYPNQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK
MUL_3658|M.ulcerans_Agy99 G----LSGFHGRYPDQLSGGQRQRMALARALAVDPEVLLLDEPFGALDAK
MMAR_0060|M.marinum_M G----LKHKANARPDMLSGGQQQRVAIARALAMAPQVMFFDEATSALDPE
MAV_0058|M.avium_104 G----LKHKAGARPATLSGGQQQRVAIARALAMSPQVMFFDEATSALDPE
MSMEG_6911|M.smegmatis_MC2_155 G----LRHKADVRPGTLSGGQQQRVAIARALAMAPQVMFFDEATSALDPE
TH_0514|M.thermoresistible__bu G----LRHKAEVRPTTLSGGQQQRVAIARALAMDPQVMFFDEATSALDPE
Mflv_0857|M.gilvum_PYR-GCK G----LRNKADVRPSTLSGGQQQRVAIARALAMSPQVMFFDEATSALDPE
Mvan_6048|M.vanbaalenii_PYR-1 G----LRNKADARPATLSGGQQQRVAIARALAMSPQVMFFDEATSALDPE
MAB_3050|M.abscessus_ATCC_1997 G----IASQKDKYPAQLSGGQQQRVAIARSLAMGPKVMLFDEPTSALDPE
Rv0933|M.tuberculosis_H37Rv GLWDAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPT
MLBr_01892|M.leprae_Br4923 G----LGGDEKKFPGEISGGMRKRAGLARALVLDPQIILCDEPDSGLDPV
* : * :*** :: :**:*.: *:::: **. ..**.
Mb2419c|M.bovis_AF2122/97 VREELRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLHKGRIEQVGS
MUL_3658|M.ulcerans_Agy99 VREDLRAWLRRLHDEVHVTTVLVTHDQAEALDVADRIAVLNSGRIEQVGS
MMAR_0060|M.marinum_M MVKGILALIADLGADG-MTMVVVTHEMGFARSTSDAVVFMDHGTVVEAGP
MAV_0058|M.avium_104 MVKGILQLIADLGAEG-MTMVVVTHEMGFARSASDAVIFMDHGKVVESGP
MSMEG_6911|M.smegmatis_MC2_155 LVKGILSLMADLAADG-MTIVAVTHEMGFARSTANTVVFMDQGRVVESGE
TH_0514|M.thermoresistible__bu LVKGILALIADLAESG-MTMVVVTHEMGFARSTADTVVFMDHGQVVESGP
Mflv_0857|M.gilvum_PYR-GCK LVKGVLALIAELASDG-MTMVVVTHEMGFARSTADQLVFMDHGQVVETGP
Mvan_6048|M.vanbaalenii_PYR-1 LVKGVLELIADLGAEG-MTMVVVTHEMGFARSSADTVVFMDHGQVVETGP
MAB_3050|M.abscessus_ATCC_1997 MVNEVLDVMVSLAKEG-MTMLVVTHEMGFARKAADRIIFMADGAIVEDSD
Rv0933|M.tuberculosis_H37Rv TTEKIEEFIRSLADRL--TVIIVTHNLAQAARISDRAALFFDGRLVEEGP
MLBr_01892|M.leprae_Br4923 RTAYLSQLIMDINAQIDATILIVTHNVNIARTVPDNMGMLFRKHLVMFGP
: : : * : ***: * .: .: : .
Mb2419c|M.bovis_AF2122/97 PTDVYDAPANAFVMSFLGAVSTLNGSLVRPHDIRVGRTPNMAVAAADGTA
MUL_3658|M.ulcerans_Agy99 PTEVYDAPTNAFVMSFLGAVSALNGALVRPHDIRVGRTPEMAVAAADGTG
MMAR_0060|M.marinum_M PEQLFEAARTERLQRFLAQVL-----------------------------
MAV_0058|M.avium_104 PEQIFEAAETERLQRFLSQVL-----------------------------
MSMEG_6911|M.smegmatis_MC2_155 PDQLFEAAETDRLRRFLSQVL-----------------------------
TH_0514|M.thermoresistible__bu PQQIFESAATERLRRFLSQVL-----------------------------
Mflv_0857|M.gilvum_PYR-GCK PEQLFEAAETDRLRRFLSQVL-----------------------------
Mvan_6048|M.vanbaalenii_PYR-1 PEQLFEAAETDRLRRFLSQVL-----------------------------
MAB_3050|M.abscessus_ATCC_1997 PESFFTNPKSERAKDFLGKILGH---------------------------
Rv0933|M.tuberculosis_H37Rv TEQLFSSPKHAETARYVAGLSGDVKDAKRGN-------------------
MLBr_01892|M.leprae_Br4923 REVLLTSDEPVVRQFLNGRRIGPIGMSEEKDESTMAEEAALLEAGHYAGG
. .
Mb2419c|M.bovis_AF2122/97 GSTGVLRAVVDRVVVLGFEVRVELTSAATGGAFTAQITRGDAEALALREG
MUL_3658|M.ulcerans_Agy99 ESTGVTRAVVDRIVVLGFEVRVELTSAATGGAFTAQITRGDAEALALQEG
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
MSMEG_6911|M.smegmatis_MC2_155 --------------------------------------------------
TH_0514|M.thermoresistible__bu --------------------------------------------------
Mflv_0857|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_6048|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3050|M.abscessus_ATCC_1997 --------------------------------------------------
Rv0933|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01892|M.leprae_Br4923 AEEVEGVPPQITVTPGMPKRKAVARRQARVRAMLPTLPKGAQAAILDDLE
Mb2419c|M.bovis_AF2122/97 DTVYVRATRVPPIAGGVSGVDDAGVERVKVTST------
MUL_3658|M.ulcerans_Agy99 DTVYVRATRVPPIAGAAPAVPDDGAGSTPRAAQIGVGGQ
MMAR_0060|M.marinum_M ---------------------------------------
MAV_0058|M.avium_104 ---------------------------------------
MSMEG_6911|M.smegmatis_MC2_155 ---------------------------------------
TH_0514|M.thermoresistible__bu ---------------------------------------
Mflv_0857|M.gilvum_PYR-GCK ---------------------------------------
Mvan_6048|M.vanbaalenii_PYR-1 ---------------------------------------
MAB_3050|M.abscessus_ATCC_1997 ---------------------------------------
Rv0933|M.tuberculosis_H37Rv ---------------------------------------
MLBr_01892|M.leprae_Br4923 GAHNYQAHEFGD---------------------------