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MTADAVSAKPMVKAELVCKDFGALKVLKGITLEVQKGQVLVLVGPSGSGKSTFLRCINHLETVSAGRLYV DGALVGYNERGGKLHEMKPRDVAKQRRDVGMVFQHFNLFPHRTALGNVVEAPIQVKGVRKAQAIEKGKEL LAQVGLADKAGAYPAQLSGGQQQRVAIARALAMDPKLMLFDEPTSALDPELVGEVLGVMKKLAAQGMTMV VVTHEMGFAREVADELVFMDAGVVVERGAPREVMANPQHERTKAFLSKVM
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2834 | - | - | 100% (260) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_2428 | - | 3e-72 | 55.78% (251) | ABC transporter-related protein |
| M. vanbaalenii PYR-1 | Mvan_4704 | - | 1e-70 | 53.41% (264) | ABC transporter-related protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1312c | oppD | 3e-35 | 36.33% (256) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_3581 | - | 1e-132 | 91.54% (260) | ABC transporter related |
| M. tuberculosis H37Rv | Rv1281c | oppD | 3e-35 | 36.33% (256) | oligopeptide-transport ATP-binding protein ABC transporter |
| M. leprae Br4923 | MLBr_01089 | - | 8e-35 | 38.36% (219) | putative ABC-transport protein, ATP-binding component |
| M. abscessus ATCC 19977 | MAB_4237c | - | 1e-78 | 56.97% (244) | amino acid ABC transporter ATP-binding protein |
| M. marinum M | MMAR_0060 | - | 1e-57 | 47.47% (257) | glutamine ABC transporter, ATP-binding protein |
| M. avium 104 | MAV_0058 | - | 3e-59 | 50.20% (249) | ABC transporter, ATP-binding protein |
| M. smegmatis MC2 155 | MSMEG_3237 | - | 1e-124 | 84.94% (259) | ATP-binding protein |
| M. thermoresistible (build 8) | TH_1784 | - | 3e-70 | 52.34% (256) | ABC transporter, ATP-binding protein GluA |
| M. ulcerans Agy99 | MUL_4001 | oppD | 1e-36 | 35.25% (261) | oligopeptide-transport ATP-binding protein ABC transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1312c|M.bovis_AF2122/97 MSPLLEVTDLAVTFRTDGDPVTAVRGISYRVEPGEVVAMVGESGSGKSAA
Rv1281c|M.tuberculosis_H37Rv MSPLLEVTDLAVTFRTDGDPVTAVRGISYRVEPGEVVAMVGESGSGKSAA
MUL_4001|M.ulcerans_Agy99 MNPLLEVTDLAVTFPTENDPVTAVRGISYQVAPGEVVAVVGESGSGKSAA
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 AMAVVGLLPEYAQVRGSVRLQGTELLGLADNAMSRFRGKAIGTVFQDPMS
Rv1281c|M.tuberculosis_H37Rv AMAVVGLLPEYAQVRGSVRLQGTELLGLADNAMSRFRGKAIGTVFQDPMS
MUL_4001|M.ulcerans_Agy99 AMAVVGLLPEYAKVRGSVRLQGTELLGLADDAMSRFRGKVIGTVFQDPMS
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 ALTPVYTVGDQIAEAIEVHQPRVGKKAARRRAVELLDLVGISQPQRRSRA
Rv1281c|M.tuberculosis_H37Rv ALTPVYTVGDQIAEAIEVHQPRVGKKAARRRAVELLDLVGISQPQRRSRA
MUL_4001|M.ulcerans_Agy99 ALTPVYTVGDQIAETIEIHQPTFSRKAARRRAVELLELVGIAQPERRARA
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 FPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQAQILDVLKAA
Rv1281c|M.tuberculosis_H37Rv FPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQAQILDVLKAA
MUL_4001|M.ulcerans_Agy99 FPHELSGGERQRVVIAIAIANDPDLLICDEPTTALDVTVQAQILDVLKTA
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 RDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVESAGVNDLYRDRRMPY
Rv1281c|M.tuberculosis_H37Rv RDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVESAGVNDLYRDRRMPY
MUL_4001|M.ulcerans_Agy99 RDVTGAGVLIITHDLGVVAEFADRALVMYAGRVVEKATVNDLYHNRRMPY
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 TVGLLGSVPRLDAAQGTRLVPIPGAPPSLAGLAPGCPFAPRCPLVIDECL
Rv1281c|M.tuberculosis_H37Rv TVGLLGSVPRLDAAQGTRLVPIPGAPPSLAGLAPGCPFAPRCPLVIDECL
MUL_4001|M.ulcerans_Agy99 TIGLLGSVPRLDATQGTRLVPIPGAPPSPAGLDRGCPFAPRCPLVIDECR
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 TAEPELLDVATDHRAACIRTELVTGRSAADIYRVKTEARPAALGDASVVV
Rv1281c|M.tuberculosis_H37Rv TAEPELLDVATDHRAACIRTELVTGRSAADIYRVKTEARPAALGDASVVV
MUL_4001|M.ulcerans_Agy99 SDEPELIEVGQNHRAACIRTDQVNGRSAADIYGVQTEATEPAPADSSVVV
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 -------------------------------------------------M
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M -------------------------------------------------M
MAV_0058|M.avium_104 -------------------------------------------------M
TH_1784|M.thermoresistible__bu -----------------------------------------MDSAGADVA
MLBr_01089|M.leprae_Br4923 --------------------------------------------------
Mb1312c|M.bovis_AF2122/97 RVRHLVKTYRLAKGVVLRRAIGEVRAVDGISLELRQGRTLGIVGESGSGK
Rv1281c|M.tuberculosis_H37Rv RVRHLVKTYRLAKGVVLRRAIGEVRAVDGISLELRQGRTLGIVGESGSGK
MUL_4001|M.ulcerans_Agy99 RVSDLVKTYPLTKGVLLRRSIGEVRAVDGVSFELRQGHTLGIVGESGSGK
Mvan_2834|M.vanbaalenii_PYR-1 MTADAVSAKPMVKAELVCKDFGALKVLKGITLEVQKGQVLVLVGPSGSGK
Mflv_3581|M.gilvum_PYR-GCK MTTSENSAHPMVKAELVCKDFGALKVLKGITLEVQKGQVLVLVGPSGSGK
MSMEG_3237|M.smegmatis_MC2_155 TTAEATSGDYMVRAESVCKNFGALKVLRGVTLNVSKGQVLVLVGPSGSGK
MAB_4237c|M.abscessus_ATCC_199 MSTIEVRG--------VRKSYGQVTALRDVNLTVHQGEVTVIIGPSGSGK
MMAR_0060|M.marinum_M TRQDAGRQPVCLAARSIHQTLGGSVVLRGVDLEVPAGTTAAVIGPSGSGK
MAV_0058|M.avium_104 S-NPASRASVSLACKDIHQTLNGNAVLRGVDLDTPAGSTVAVIGPSGSGK
TH_1784|M.thermoresistible__bu VADPAAEAVPMISMRGVNKYFGSLHVLRDINLDVARGQVVVVLGPSGSGK
MLBr_01089|M.leprae_Br4923 -------MAEIVLEHVNKNYPNGATAVHDLSITVADGEFLILIGPSGCGK
. . .: .: : * ::* **.**
Mb1312c|M.bovis_AF2122/97 STTLHEILELAAPQSGSIEVLGTDVATLGTA---------ERRSLRRDIQ
Rv1281c|M.tuberculosis_H37Rv STTLHEILELAAPQSGSIEVLGTDVATLGTA---------ERRSLRRDIQ
MUL_4001|M.ulcerans_Agy99 STTLHQILELAAPQSGSIEVLGTDVTTLTAS---------SRRALRRDIQ
Mvan_2834|M.vanbaalenii_PYR-1 STFLRCINHLETVSAGRLYVDGALVGYNERGGKLHEMKPRDVAKQRRDVG
Mflv_3581|M.gilvum_PYR-GCK STLLRCINHLETVSAGRLYVDGTLVGYHERGGKLYEMKPRDVARQRRDVG
MSMEG_3237|M.smegmatis_MC2_155 STFLRCINHLETVSAGRLYVDGQLVGYRERGGKLHEMKPSDVAKQRRDVG
MAB_4237c|M.abscessus_ATCC_199 STLLRALNHLEKVDAGTIRIDGELIGYRQRGSVLYELPERAILRQRSQVG
MMAR_0060|M.marinum_M STLLRTLNRLHEPDSGDILLDGRSVLRD------------NPNDLRQRIG
MAV_0058|M.avium_104 STLLRTLNRLYEPDRGDILLDGRSVLHD------------DPDQLRQRIG
TH_1784|M.thermoresistible__bu STLCRTLNRLEPIDSGAISIDGVALPAEGR----------ELARLRADVG
MLBr_01089|M.leprae_Br4923 TTTLNMIAGLEDISSGELRIDGDRVNEKAPK--------------DRDIA
:* . : * . * : : * : :
Mb1312c|M.bovis_AF2122/97 VVFQDPVASLDPRLPVFDLIAEPLQANGFGKNETHARVAELLDIVGLRHG
Rv1281c|M.tuberculosis_H37Rv VVFQDPVASLDPRLPVFDLIAEPLQANGFGKNETHARVAELLDIVGLRHG
MUL_4001|M.ulcerans_Agy99 VVFQDPVASLDPRLPISDLLAEPLQANGFNKTDTQDRVAELLDIVGLRRS
Mvan_2834|M.vanbaalenii_PYR-1 MVFQH-FNLFPHRTALGNVVEAPIQVKGVRKAQAIEKGKELLAQVGLAD-
Mflv_3581|M.gilvum_PYR-GCK MVFQH-FNLFPHRTALGNVVEAPIQVKGVKKDEAVTRGRELLAQVGLAD-
MSMEG_3237|M.smegmatis_MC2_155 MVFQH-FNLFPHRTALANIIEAPIKVKGVKKKEAIDRARDLLNQVGLAD-
MAB_4237c|M.abscessus_ATCC_199 FVFQN-FNLFPHLTVLENVIEAPLAARRAPRAELEAEATRLLERVGVAD-
MMAR_0060|M.marinum_M MVFQH-FNLFPHRNVVDNVTLAPRKLRGLSNEEARMLALDQLDRVGLKH-
MAV_0058|M.avium_104 MVFQH-FNLFPHRTVLDNVALAPRKLRRLPAEAARELALTQLDRVGLKH-
TH_1784|M.thermoresistible__bu MVFQQ-FNLFAHKTIVDNVALGPMKVRKTPREQARAEAMALLERVGVAD-
MLBr_01089|M.leprae_Br4923 MVFQS-YALYPHMTVRQNIAFP-LMLAKVKKAEIAQKVSETAQILDLTD-
.*** :: :.:
Mb1312c|M.bovis_AF2122/97 DASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGIINL
Rv1281c|M.tuberculosis_H37Rv DASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGIINL
MUL_4001|M.ulcerans_Agy99 DASRYPAEFSGGQKQRIGIARALALQPKILALDEPVSALDVSIQAGIINL
Mvan_2834|M.vanbaalenii_PYR-1 KAGAYPAQLSGGQQQRVAIARALAMDPKLMLFDEPTSALDPELVGEVLGV
Mflv_3581|M.gilvum_PYR-GCK KADAYPAQLSGGQQQRVAIARALAMDPKLMLFDEPTSALDPELVGEVLAV
MSMEG_3237|M.smegmatis_MC2_155 KAEAYPAQLSGGQQQRVAIARALAMNPKLMLFDEPTSALDPELVGDVLGV
MAB_4237c|M.abscessus_ATCC_199 KAAQYPRRLSGGQQQRVAIARALALRPKVILFDEPTSALDPELVTEVLDV
MMAR_0060|M.marinum_M KANARPDMLSGGQQQRVAIARALAMAPQVMFFDEATSALDPEMVKGILAL
MAV_0058|M.avium_104 KAGARPATLSGGQQQRVAIARALAMSPQVMFFDEATSALDPEMVKGILQL
TH_1784|M.thermoresistible__bu QADKYPAQLSGGQQQRVAIARSLAMNPKVMLFDEPTSALDPEMINEVLAV
MLBr_01089|M.leprae_Br4923 LLDRKPSQLSGGQRQRVAMGRAIVRHPKAFLMDEPLSNLDAKLRVRTRGE
* :****:**:.:.*::. *: : :**. * ** .:
Mb1312c|M.bovis_AF2122/97 LLDLQEQFGLSYLFVSHDLSVVKHLAHQVAVMLAGTVVEQGDSEEVFGNP
Rv1281c|M.tuberculosis_H37Rv LLDLQEQFGLSYLFVSHDLSVVKHLAHQVAVMLAGTVVEQGDSEEVFGNP
MUL_4001|M.ulcerans_Agy99 LLDLQAGFKLSYLFVSHDLSVVKHLANSVVVMFAGSIVEQGNSQEVFSNP
Mvan_2834|M.vanbaalenii_PYR-1 MKKLAAQG-MTMVVVTHEMGFAREVADELVFMDAGVVVERGAPREVMANP
Mflv_3581|M.gilvum_PYR-GCK MKKLAAQG-MTMVVVTHEMGFAREVADELVFMDEGVVVERGNPREVMSNP
MSMEG_3237|M.smegmatis_MC2_155 MKKLASEG-MTMVVVTHEMGFAREVADKLVFMDGGVIVESGDPREVMANP
MAB_4237c|M.abscessus_ATCC_199 IAQLARDG-ATLVIVTHEIGLAREIADTVVFMDRGAIVEQGPPKEVLDSP
MMAR_0060|M.marinum_M IADLGADG-MTMVVVTHEMGFARSTSDAVVFMDHGTVVEAGPPEQLFEAA
MAV_0058|M.avium_104 IADLGAEG-MTMVVVTHEMGFARSASDAVIFMDHGKVVESGPPEQIFEAA
TH_1784|M.thermoresistible__bu MSALAADG-MTMLVVTHEMGFARRASDRVVFMSDGAIVEDAEPARFFEDP
MLBr_01089|M.leprae_Br4923 IARLQRRLGATTVYVTHDQTEAMTLGDRVVVMRSGVVQQIGTPDELYERP
: * : : *:*: . .. : .* * : : . . .. .
Mb1312c|M.bovis_AF2122/97 KHEYTRRLLGAVPQPDPARRG-----------------------------
Rv1281c|M.tuberculosis_H37Rv KHEYTRRLLGAVPQPDPARRG-----------------------------
MUL_4001|M.ulcerans_Agy99 QHEYTQRLLGAVPQPIPGNAD-----------------------------
Mvan_2834|M.vanbaalenii_PYR-1 QHERTKAFLSKVM-------------------------------------
Mflv_3581|M.gilvum_PYR-GCK QHERTKAFLSKVM-------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 KHERTKAFLSKVM-------------------------------------
MAB_4237c|M.abscessus_ATCC_199 SHPRTASFLSKVLS------------------------------------
MMAR_0060|M.marinum_M RTERLQRFLAQVL-------------------------------------
MAV_0058|M.avium_104 ETERLQRFLSQVL-------------------------------------
TH_1784|M.thermoresistible__bu QTDRARDFLGKILHH-----------------------------------
MLBr_01089|M.leprae_Br4923 VNLFVAGFIGSPVMNFFPAKLTPNGLTLPLGELNLSRDVQAMIGQHPVPD
::.
Mb1312c|M.bovis_AF2122/97 --------------------------------------------------
Rv1281c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4001|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 RVIVGVRPEHLTDAKLIDAHQHGTVLTFKVKVDLVESLGADKYIYFTTTG
Mb1312c|M.bovis_AF2122/97 --------------------------------------------------
Rv1281c|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4001|M.ulcerans_Agy99 --------------------------------------------------
Mvan_2834|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3581|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_3237|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4237c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_0060|M.marinum_M --------------------------------------------------
MAV_0058|M.avium_104 --------------------------------------------------
TH_1784|M.thermoresistible__bu --------------------------------------------------
MLBr_01089|M.leprae_Br4923 CDVYSAQLDELASELEVRENQFVARVSAESKMAIGESIELAFGTAKIAVF
Mb1312c|M.bovis_AF2122/97 ----------------
Rv1281c|M.tuberculosis_H37Rv ----------------
MUL_4001|M.ulcerans_Agy99 ----------------
Mvan_2834|M.vanbaalenii_PYR-1 ----------------
Mflv_3581|M.gilvum_PYR-GCK ----------------
MSMEG_3237|M.smegmatis_MC2_155 ----------------
MAB_4237c|M.abscessus_ATCC_199 ----------------
MMAR_0060|M.marinum_M ----------------
MAV_0058|M.avium_104 ----------------
TH_1784|M.thermoresistible__bu ----------------
MLBr_01089|M.leprae_Br4923 DADSGVNLTVSAPTDA