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MTYNAGGYGPAGPPPPGYPAPGYPGYPPAGYGAPPQYWQPPGYAPGYGAPGYPPQFGLPPVIKPGVVPLR PLTLSDIFNGAVAYIRTNPKATLGLTAIVVIASQIVALLLSLWPFAFTGQVASTLDGDEASTEVLVSWMA SSLATAITTGLSTTLLSGLLTVVIGRSVFGADITIGEAWRRLRPRLWALIGFTVLKTLALIVWFGVVLLI VVLAVAVIDGPAAFLIAAPLVLASILAAVWVSVMLTFAPAVIVLERRDIVTSVKRSFALIKSDFWRVFGI WLLAAIVAQFIAGAVSIPFSIGGQAVLTASATTTAAMISMVLFSVGGAVGQIITGPFSAGVTVLQYTDRR IRAEAFDLVLQTGAAAGPQAPADSTDDLWLTGPR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_5452 | - | - | 100% (384) | putative transmembrane protein |
M. vanbaalenii PYR-1 | Mvan_4673 | - | 1e-11 | 27.24% (323) | hypothetical protein Mvan_4673 |
M. vanbaalenii PYR-1 | Mvan_4486 | - | 4e-10 | 33.52% (179) | hypothetical protein Mvan_4486 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3714 | - | 6e-99 | 48.50% (400) | transmembrane protein |
M. gilvum PYR-GCK | Mflv_1340 | - | 1e-154 | 71.65% (381) | putative transmembrane protein |
M. tuberculosis H37Rv | Rv3689 | - | 6e-99 | 48.50% (400) | transmembrane protein |
M. leprae Br4923 | MLBr_00222 | ftsH | 2e-05 | 37.68% (69) | putative integral membrane peptidase |
M. abscessus ATCC 19977 | MAB_0392c | - | 6e-71 | 40.36% (389) | hypothetical protein MAB_0392c |
M. marinum M | MMAR_5199 | - | 1e-101 | 52.35% (405) | hypothetical protein MMAR_5199 |
M. avium 104 | MAV_0415 | - | 2e-92 | 49.48% (388) | hypothetical protein MAV_0415 |
M. smegmatis MC2 155 | MSMEG_6216 | - | 4e-97 | 52.30% (369) | integral membrane protein |
M. thermoresistible (build 8) | TH_3239 | - | 3e-93 | 56.62% (325) | PUTATIVE putative putative conserved transmembrane protein |
M. ulcerans Agy99 | MUL_4272 | - | 1e-101 | 51.97% (406) | hypothetical protein MUL_4272 |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_5452|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1340|M.gilvum_PYR-GCK -------------------------------------------------- Mb3714|M.bovis_AF2122/97 -------------------------------------------------- Rv3689|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5199|M.marinum_M -------------------------------------------------- MUL_4272|M.ulcerans_Agy99 -------------------------------------------------- MAV_0415|M.avium_104 -------------------------------------------------- MSMEG_6216|M.smegmatis_MC2_155 -------------------------------------------------- TH_3239|M.thermoresistible__bu -------------------------------------------------- MAB_0392c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_00222|M.leprae_Br4923 MLLMNRKNVIRMVTAIAVVVLLGWSFFYFSDDTRGYKFVDTSVAMSQING Mvan_5452|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1340|M.gilvum_PYR-GCK -------------------------------------------------- Mb3714|M.bovis_AF2122/97 -------------------------------------------------- Rv3689|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_5199|M.marinum_M -------------------------------------------------- MUL_4272|M.ulcerans_Agy99 -------------------------------------------------- MAV_0415|M.avium_104 -------------------------------------------------- MSMEG_6216|M.smegmatis_MC2_155 -------------------------------------------------- TH_3239|M.thermoresistible__bu -------------------------------------------------- MAB_0392c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_00222|M.leprae_Br4923 HNVKSAQIDDREQQLRLTLKKGNNDTDGSDKVITKYPTGYAVDLFNALSA Mvan_5452|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1340|M.gilvum_PYR-GCK -------------------------------------------------- Mb3714|M.bovis_AF2122/97 -------------------------------------------MHKRYAP Rv3689|M.tuberculosis_H37Rv -------------------------------------------MHKRYAP MMAR_5199|M.marinum_M -------------------------------------------------- MUL_4272|M.ulcerans_Agy99 -------------------------------------------------- MAV_0415|M.avium_104 -------------------------------------------------- MSMEG_6216|M.smegmatis_MC2_155 -------------------------------------------------- TH_3239|M.thermoresistible__bu -------------------------------------------------- MAB_0392c|M.abscessus_ATCC_199 -------------------------------------------------- MLBr_00222|M.leprae_Br4923 KNTKVTTAVNEGSILGELLVYVLPLLLLVGLFVMFSRMQGGARMGFGFGK Mvan_5452|M.vanbaalenii_PYR-1 -------------------------------------------MTYNAGG Mflv_1340|M.gilvum_PYR-GCK -------------------------------------------MTYDAGG Mb3714|M.bovis_AF2122/97 QRPKPDTETYIEKCTDRRQDGGHDERRQLLRPVSMLPPGYPVEPPPVAPG Rv3689|M.tuberculosis_H37Rv QRPKPDTETYIEKCTDRRQDGGHDERRQLLRPVSMLPPGYPVEPPPVAPG MMAR_5199|M.marinum_M -------------------------------MSTLPPPGYPVEPNSGAPG MUL_4272|M.ulcerans_Agy99 -------------------------------MSTLPPPGYPVEPNSGAPG MAV_0415|M.avium_104 ------------MCATLRAG----ARVNVVKWSGRRQDGAHDEPPVHEPR MSMEG_6216|M.smegmatis_MC2_155 ----------------------------------MRP----------GPD TH_3239|M.thermoresistible__bu -------------------------------------------VNPMAPM MAB_0392c|M.abscessus_ATCC_199 ----------------------------------MSNDEGGVTPSPLPPG MLBr_00222|M.leprae_Br4923 SRAKQLSKDMPKTTFADVAGVDEAVEELYEIKDFLQNPCRYQTLGAKIPK Mvan_5452|M.vanbaalenii_PYR-1 YGPAGPPP--------------PGYPAPG------YPGYPPAGYGAPPQY Mflv_1340|M.gilvum_PYR-GCK YGPAGFPP--------------PRYP-------------PPPGYGPPPG- Mb3714|M.bovis_AF2122/97 YAPAGYPP---------YPATPPGYGPP-------GYGAPP-SYGPPP-G Rv3689|M.tuberculosis_H37Rv YAPAGYPP---------YPATPPGYGPP-------GYGAPP-SYGPPP-G MMAR_5199|M.marinum_M YEAAGYPPSG-------YADPPPAYGPPPAYGPPPGYGAPPPGYGPPPPG MUL_4272|M.ulcerans_Agy99 YEAAGYPPSG-------YADPPPAYGPPPAYGPPPGYGAPPPGYGPPP-G MAV_0415|M.avium_104 GSVSAPPPGY-------PVGPPPAYGSQSHYG--TQYGAQYPGQYGVH-- MSMEG_6216|M.smegmatis_MC2_155 GGFAPYPP-------------PQAYPVH---------------------- TH_3239|M.thermoresistible__bu RQTA---------------------------------------------- MAB_0392c|M.abscessus_ATCC_199 PSPAYPPP-------------APGYPPAG-----------TAGYPPPGFA MLBr_00222|M.leprae_Br4923 GVLLYGPPGTGKTLLARAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDL Mvan_5452|M.vanbaalenii_PYR-1 WQPPGY-------APGYGAPGYPPQ--FGLPP-----------------V Mflv_1340|M.gilvum_PYR-GCK WQPP-----------GYGAPGYPPP--YGGPP-----------------V Mb3714|M.bovis_AF2122/97 YGPPL--------GYPAAPPGCGPPPGYG-PPLGYGPPL-------APGA Rv3689|M.tuberculosis_H37Rv YGPPL--------GYPAAPPGCGPPPGYG-PPLGYGPPV-------APGA MMAR_5199|M.marinum_M YGPPP--------GYGPPPPGYGPPPGYGPPPPGYGPPL-------VPGA MUL_4272|M.ulcerans_Agy99 YAPPPP-------GYGPPP-GYGPPPGYGPPPPGYGPPL-------VPGA MAV_0415|M.avium_104 YGPPP----------TYPPPGYPPAPAFG-PPPGYG-------------V MSMEG_6216|M.smegmatis_MC2_155 -------------------PGYASAPGFG--------------------A TH_3239|M.thermoresistible__bu -------------------------------------------------- MAB_0392c|M.abscessus_ATCC_199 YQPPP---------PGYQNPSAVPYWVTPEPP-----------------A MLBr_00222|M.leprae_Br4923 FDQAKQNSPCIIFVDEIDAVGRQRGTGLGGGHDEREQTLNQLLVEMDGFG Mvan_5452|M.vanbaalenii_PYR-1 IKPGVVPLRPLTLSDIFN---------------------GAVAYIRTNPK Mflv_1340|M.gilvum_PYR-GCK LKPGVVPLRPLTLSDIFN---------------------GAVAYVRANPK Mb3714|M.bovis_AF2122/97 VKPGIIPLRPLTLSDIFN---------------------GAVGYIRANPK Rv3689|M.tuberculosis_H37Rv VKPGIIPLRPLTLSDIFN---------------------GAVGYIRANPK MMAR_5199|M.marinum_M VKPGIIPLRPLTLSDIFN---------------------GAVGYIRANPK MUL_4272|M.ulcerans_Agy99 VKPGIIPLRPLTLSDIFN---------------------GAVGYIRANPK MAV_0415|M.avium_104 LKPGIIPLRPLTLGDIFN---------------------GAVGYIRANPK MSMEG_6216|M.smegmatis_MC2_155 PVPGIVALRPLSLSDIFN---------------------GAVAYIRRNPK TH_3239|M.thermoresistible__bu LKPGVIPLRPLTLSDIFN---------------------GAVAYIRTNPK MAB_0392c|M.abscessus_ATCC_199 LKPGVIPLRPLDLSSLYN---------------------GAIAAIRANPK MLBr_00222|M.leprae_Br4923 DRAGVILIAATNRPDILDPALLRPGRFDRQIPVSNPDLAGRRAVLRVHSK .*:: : . .: : * . :* :.* Mvan_5452|M.vanbaalenii_PYR-1 ----------ATLGLTAIVVIASQIVALLLSLWPFAF--TGQVASTLDGD Mflv_1340|M.gilvum_PYR-GCK ----------ATLGLTTIVVVAAQILSLVLSLVPFTF--TDMVADGLGED Mb3714|M.bovis_AF2122/97 ----------ATLGLTAMVVVTLQIISLVALFGPMTA--FGDIVTGEPDE Rv3689|M.tuberculosis_H37Rv ----------ATLGLTAMVVVTLQIISLVALFGPMTA--FGDIVTGEPDE MMAR_5199|M.marinum_M ----------ATLGLTAIVVVVMQVITLLATIGPLEA--ASRFDT-HPSE MUL_4272|M.ulcerans_Agy99 ----------ATLGLTAIVVVVMQVITLLAAIGPLEA--ASRFDT-HPSE MAV_0415|M.avium_104 ----------ATLGLTAIVVIAMQIITKAAVLGPLAA--YGRFTGDRSDE MSMEG_6216|M.smegmatis_MC2_155 ----------ATLGLTTIVVVLAQLVTLLLQVGPLAA--MGGLGSEVQGE TH_3239|M.thermoresistible__bu ----------ATLGLTAIVVVVAQLLALVLQIGSLAA--TGDLVSSVRGD MAB_0392c|M.abscessus_ATCC_199 ----------TTLGLTAIVVIVSQLLIFGIQAAPATAVLTGAASFDKNTE MLBr_00222|M.leprae_Br4923 GKPIADDADLDGLAKRTVGMTGADLANVVNEAALLTARENGLVITGPALE *. :: : :: . : Mvan_5452|M.vanbaalenii_PYR-1 EASTEVLVS-WMASSLATAITTGLSTTLLSG---------------LLTV Mflv_1340|M.gilvum_PYR-GCK EASVQVIVG-WVASSLAGGIATALAATVLAG---------------MLTV Mb3714|M.bovis_AF2122/97 LT-GAVVGG-WSASFGASLLVSWLAGVLLSG---------------MLTV Rv3689|M.tuberculosis_H37Rv LT-GAVVGG-WSASFGASLLVSWLAGVLLSG---------------MLTV MMAR_5199|M.marinum_M LS-WGVVGA-WTGSAAAGLLVSWLGGMLLSG---------------ILTV MUL_4272|M.ulcerans_Agy99 LS-WGVVGA-WTGSAAAGLLVSWLGGMLLSG---------------ILTV MAV_0415|M.avium_104 LT-AGVLGA-WSVSVGAGVLVGWLGGMLLSG---------------MLTV MSMEG_6216|M.smegmatis_MC2_155 APSTGAVAM-FSGATLAGVLVTQLASVLLTG---------------MLTV TH_3239|M.thermoresistible__bu DVSTVGLSW-ADLASVTTAVANTLALLVLSG---------------MLTV MAB_0392c|M.abscessus_ATCC_199 DSFGAAFGLGYIGGQLIGAVVTSLVTIILSG---------------MLTV MLBr_00222|M.leprae_Br4923 EAVDRVIGGPRRKGRIISEQEKKITAYHEGGHTLAAWAMPDIEPIYKVTI . . : * :*: Mvan_5452|M.vanbaalenii_PYR-1 VIGRSVFGADITIGEAWRRLRPR-------LWALIGFTVLKTLALIVWFG Mflv_1340|M.gilvum_PYR-GCK VIGRSVFGAGITVGEAWKRLRPR-------FWPLIGFTVLKMLVFLVGLV Mb3714|M.bovis_AF2122/97 IVGRAVFGSPITVGEAWAKVRGR-------LLALFGLALLEAAGVVAVLG Rv3689|M.tuberculosis_H37Rv IVGRAVFGSPITVGEAWAKVRGR-------LLALFGLALLEAAGVVAVLG MMAR_5199|M.marinum_M VVGRAVFGSPITISEAWARVRGR-------ILALIGLALLEGAGLVALAG MUL_4272|M.ulcerans_Agy99 VVGRAVFGSPITISEAWARVRGR-------ILALIGLALLEGAGLVALAG MAV_0415|M.avium_104 IVGRAVFGSSITVGETWTKIRGR-------LPALLGLALLEAVVVAAIAG MSMEG_6216|M.smegmatis_MC2_155 IIGRSIFGGTVTIGQAWERLRGR-------LLALIGLTLLEAVVLLAVVL TH_3239|M.thermoresistible__bu VIGRAVFGAGITISEAWERLRGR-------LWALIGFSVLELLAVVVIVV MAB_0392c|M.abscessus_ATCC_199 TIGRSVFGERTTIKEAWQRAKPR-------IWALLGVAVVELVLFAVVLG MLBr_00222|M.leprae_Br4923 LARGRTGGHAVAVPEEDKGLRTRSEMIAQLVFAMGGRAAEELVFREPTTG * :: : : * . .: * : : Mvan_5452|M.vanbaalenii_PYR-1 VVLLIVVLAVAVIDGPAAFLIAAPLVLASI---LAAVWVSVMLTFAPAVI Mflv_1340|M.gilvum_PYR-GCK LVVGIIGATGALTTGVVAFAVAIPLVLAAV---LAAVWLSVMLTFAPVII Mb3714|M.bovis_AF2122/97 LAVVILSGVAAAANEAAAALLGFPLLLVVG---VSLAYLYVVLLFAPVLI Rv3689|M.tuberculosis_H37Rv LAVVILSGVAAAANEAAAALLGFPLLLVVG---VSLAYLYVVLLFAPVLI MMAR_5199|M.marinum_M LVVVILVGVAAAANGATAALLGFPLVLLVG---LLVAYLYTVLMFAPVLI MUL_4272|M.ulcerans_Agy99 LVVVILVGVAAAANGATAALLGFPLVLLVG---LLVAYLYTVLMFAPVLI MAV_0415|M.avium_104 LVVVVIAILAAIGNAAAAVVLGIPLVLTVI---AVLVYLYTVVLFAPVLI MSMEG_6216|M.smegmatis_MC2_155 VVIGLIAAAGAVGGAVAAFVMGVPLVLAAV---LGALFGLTVLLFAPVLI TH_3239|M.thermoresistible__bu LAVVMGAALAAAG-GAGAGALIVLLFLGTV---ALLAYLATVLSFGPPVI MAB_0392c|M.abscessus_ATCC_199 FGVAVVVGLALTVGPAGAIPAGLLLALAYF---LFYLYLIPVFSLVPSVL MLBr_00222|M.leprae_Br4923 AVSDIEKATKIARSMVTEFGMSSKLGAVRYGSEHGDPFLGRTMGTQADYS : * : . . Mvan_5452|M.vanbaalenii_PYR-1 VLERRDIVTSVKRSFALIKSDFWRVFGIW--LLAAIVAQFIAGAVSIPFS Mflv_1340|M.gilvum_PYR-GCK VLERRDIVTAVKRSFTLIKADFWRVFGIW--LLAAIVAQFIAGAVSIPFT Mb3714|M.bovis_AF2122/97 VLERLPIVEAITRSFALVRHGFWRVLGIR--LLTVLVVGVVGNAIAAPFM Rv3689|M.tuberculosis_H37Rv VLERLPIVEAITRSFALVRHGFWRVLGIR--LLTVLVVGVVGNAIAAPFM MMAR_5199|M.marinum_M VLERLPLVDAITRSFALVTGGFWRVLGIR--LLTAIVVGLVGGAISAPFG MUL_4272|M.ulcerans_Agy99 VLERLPLVDAITRSFALVTGGFWRVLGIR--LLTAIVVGLVGGAISAPFG MAV_0415|M.avium_104 VLERLPVLDAITRSFRLVRRGFWRVLGIR--ALAFLVTAVVANAVAVPFS MSMEG_6216|M.smegmatis_MC2_155 VLERLDVFAAIARSFALVKTGFWRVLGIW--LLASLVASVIASAVGAPFS TH_3239|M.thermoresistible__bu VLERLGVFAAIARSFGLVRNSFWRVFGIR--LLAWLVAGVISVAVAVPFS MAB_0392c|M.abscessus_ATCC_199 ILEQQSVFGAIGRSVSLVRKGFWRLLGIL--VLTGFIVGFVSMIIGMPFI MLBr_00222|M.leprae_Br4923 HEVARDIDDEVRKLIEAAHTEAWEILTEYRDVLDTLAGELLEKETLHRPE : : : . *.:: * : .: Mvan_5452|M.vanbaalenii_PYR-1 IGGQAVLTA-----SAT---TTAAMISMVLFSVGGAVGQIITGPFSAGVT Mflv_1340|M.gilvum_PYR-GCK LGGQIAFSA-----SAT---TASAMLAFALFAIGGAIGQIITGPFTAGVS Mb3714|M.bovis_AF2122/97 IVGEIVTAV-----TASDGSVTMRLVGATLSAIGVTIGQIVTAPFSAGVV Rv3689|M.tuberculosis_H37Rv IVGEIVTAV-----TASDGSVTMRLVGATLSAIGVTIGQIVTAPFSAGVV MMAR_5199|M.marinum_M IVGQILLGA-----TASEGSTGMFLVGMTLSSIGSAISQIITAPFTAGVV MUL_4272|M.ulcerans_Agy99 IVGQILLGA-----TASEGSTGMFLVGMTLSSIGSAISQIITAPFTAGVV MAV_0415|M.avium_104 IVGQVFQIS-----SSG----TAFLISTAILSVGAAIGEIITAPFNAGVI MSMEG_6216|M.smegmatis_MC2_155 IVGQLLTMS-----PDG---VGMSIVGLVLVAVGGTIGQIVTAPFAAGVD TH_3239|M.thermoresistible__bu VAGGLFGLS-----ADS---SALAIISLTLIAIGGAVGQIITTPFNAGVI MAB_0392c|M.abscessus_ATCC_199 LVGEVAAFAG----SDPNNLGPKMLLIFALAAVGAVIAQIISLPFKAAVN MLBr_00222|M.leprae_Br4923 LEGIFASVEKRPRLTMFDDFGGRIPSDKPPIKTPGELAIERGEPWPQPVP : * . :. *: * Mvan_5452|M.vanbaalenii_PYR-1 VLQYTDRRIRAEAFDLVLQTG---AAAGPQA------------------- Mflv_1340|M.gilvum_PYR-GCK VLQYADRRIRAEAFDLVLQTG---ATAGPYA------------------- Mb3714|M.bovis_AF2122/97 VLLYTDRRIRAEAFDLVLQTGLEAGPAGGPA------------------- Rv3689|M.tuberculosis_H37Rv VLLYTDRRIRAEAFDLVLQTGLEAGPAGGPA------------------- MMAR_5199|M.marinum_M VLLYTDRRMRAEAFDLVLQT----GAAGGPA------------------- MUL_4272|M.ulcerans_Agy99 VLLYTDRRMRAEAFDLVLQT----GAAGGPA------------------- MAV_0415|M.avium_104 VLLYTDRRMRAEAFDLLQS-----GAAQGSY------------------- MSMEG_6216|M.smegmatis_MC2_155 VLLYTDRRIRAEAFDLVLRTG-AYTPAPPAA------------------- TH_3239|M.thermoresistible__bu VLLYADRRIRAEAFDLVLQTG----ATAGPA------------------- MAB_0392c|M.abscessus_ATCC_199 VLLYTDQRMRTEALDLVLQTEAR-TRERLGQ------------------- MLBr_00222|M.leprae_Br4923 EPAFKAAIARASQAAEASHQAAQSDTDGPPGQGANGSHAGDRQRQHGPTQ : *:. Mvan_5452|M.vanbaalenii_PYR-1 --------------PADSTDDLWLTGPR---------------------- Mflv_1340|M.gilvum_PYR-GCK --------------PADSTDDLWLTR------------------------ Mb3714|M.bovis_AF2122/97 --------------PVESTDNLWLTRPF---------------------- Rv3689|M.tuberculosis_H37Rv --------------PVESTDNLWLTRPF---------------------- MMAR_5199|M.marinum_M --------------AVESTDNLWLTRPL---------------------- MUL_4272|M.ulcerans_Agy99 --------------AVESTDTLWLTRPL---------------------- MAV_0415|M.avium_104 --------------AAASTDNLWLTRPR---------------------- MSMEG_6216|M.smegmatis_MC2_155 --------------PAESTDQLWLVRHF---------------------- TH_3239|M.thermoresistible__bu --------------HAESTDQLWLPRPTTPWAAHHPR------------- MAB_0392c|M.abscessus_ATCC_199 --------------PGIDPDSLWLPMRPPVQV------------------ MLBr_00222|M.leprae_Br4923 PDYGAPPGWHAPGWPPQQPPDYWYPPEQQPSQSPYWPQPAPSYPGQAPPP .. * Mvan_5452|M.vanbaalenii_PYR-1 ---------------------------------------- Mflv_1340|M.gilvum_PYR-GCK ---------------------------------------- Mb3714|M.bovis_AF2122/97 ---------------------------------------- Rv3689|M.tuberculosis_H37Rv ---------------------------------------- MMAR_5199|M.marinum_M ---------------------------------------- MUL_4272|M.ulcerans_Agy99 ---------------------------------------- MAV_0415|M.avium_104 ---------------------------------------- MSMEG_6216|M.smegmatis_MC2_155 ---------------------------------------- TH_3239|M.thermoresistible__bu ---------------------------------------- MAB_0392c|M.abscessus_ATCC_199 ---------------------------------------- MLBr_00222|M.leprae_Br4923 YPSYPPCPSYPPPGQSAPDAGKPPAQLDEGVSPSNPPAHG