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LHKRYAPQRPKPDTETYIEKCTDRRQDGGHDERRQLLRPVSMLPPGYPVEPPPVAPGYAPAGYPPYPATP PGYGPPGYGAPPSYGPPPGYGPPLGYPAAPPGCGPPPGYGPPLGYGPPLAPGAVKPGIIPLRPLTLSDIF NGAVGYIRANPKATLGLTAMVVVTLQIISLVALFGPMTAFGDIVTGEPDELTGAVVGGWSASFGASLLVS WLAGVLLSGMLTVIVGRAVFGSPITVGEAWAKVRGRLLALFGLALLEAAGVVAVLGLAVVILSGVAAAAN EAAAALLGFPLLLVVGVSLAYLYVVLLFAPVLIVLERLPIVEAITRSFALVRHGFWRVLGIRLLTVLVVG VVGNAIAAPFMIVGEIVTAVTASDGSVTMRLVGATLSAIGVTIGQIVTAPFSAGVVVLLYTDRRIRAEAF DLVLQTGLEAGPAGGPAPVESTDNLWLTRPF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3714 | - | - | 100% (451) | transmembrane protein |
| M. bovis AF2122 / 97 | Mb1265c | - | 9e-12 | 34.81% (158) | hypothetical protein Mb1265c |
| M. bovis AF2122 / 97 | Mb2590 | - | 2e-11 | 28.30% (265) | hypothetical protein Mb2590 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_1340 | - | 4e-95 | 51.97% (381) | putative transmembrane protein |
| M. tuberculosis H37Rv | Rv3689 | - | 0.0 | 99.78% (451) | transmembrane protein |
| M. leprae Br4923 | MLBr_01334 | - | 2e-06 | 40.00% (80) | hypothetical protein MLBr_01334 |
| M. abscessus ATCC 19977 | MAB_0392c | - | 4e-72 | 40.44% (413) | hypothetical protein MAB_0392c |
| M. marinum M | MMAR_5199 | - | 1e-166 | 73.03% (419) | hypothetical protein MMAR_5199 |
| M. avium 104 | MAV_0415 | - | 1e-129 | 58.39% (435) | hypothetical protein MAV_0415 |
| M. smegmatis MC2 155 | MSMEG_6216 | - | 3e-95 | 53.02% (381) | integral membrane protein |
| M. thermoresistible (build 8) | TH_3239 | - | 2e-87 | 53.89% (334) | PUTATIVE putative putative conserved transmembrane protein |
| M. ulcerans Agy99 | MUL_4272 | - | 1e-166 | 72.49% (418) | hypothetical protein MUL_4272 |
| M. vanbaalenii PYR-1 | Mvan_5452 | - | 9e-96 | 47.16% (405) | putative transmembrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3714|M.bovis_AF2122/97 MHKRYAPQRPKPDTETYIEKCTDRRQDGGHDERRQLLRPVSMLPPGYPVE
Rv3689|M.tuberculosis_H37Rv MHKRYAPQRPKPDTETYIEKCTDRRQDGGHDERRQLLRPVSMLPPGYPVE
MMAR_5199|M.marinum_M --------------------------------------MSTLPPPGYPVE
MUL_4272|M.ulcerans_Agy99 --------------------------------------MSTLPPPGYPVE
MAV_0415|M.avium_104 -------------------MCATLRAG----ARVNVVKWSGRRQDGAHDE
Mflv_1340|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_5452|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3239|M.thermoresistible__bu --------------------------------------------------
MSMEG_6216|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0392c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_01334|M.leprae_Br4923 --------------------------------------------------
Mb3714|M.bovis_AF2122/97 PPPVAPGYAPAGYPP--YPATPPGYGPP-------GYGAPP-SYGPPP-G
Rv3689|M.tuberculosis_H37Rv PPPVAPGYAPAGYPP--YPATPPGYGPP-------GYGAPP-SYGPPP-G
MMAR_5199|M.marinum_M PNSGAPGYEAAGYPPSGYADPPPAYGPPPAYGPPPGYGAPPPGYGPPPPG
MUL_4272|M.ulcerans_Agy99 PNSGAPGYEAAGYPPSGYADPPPAYGPPPAYGPPPGYGAPPPGYGPPP-G
MAV_0415|M.avium_104 PPVHEPRGSVSAPPPGYPVGPPPAYGSQSHYG--TQYGAQYPGQYGVH--
Mflv_1340|M.gilvum_PYR-GCK MTYDAGGYGPAGFPPPRYP--------------------PPPGYGPPPG-
Mvan_5452|M.vanbaalenii_PYR-1 MTYNAGGYGPAGPPPPGYPAPG-------------YPGYPPAGYGAPPQY
TH_3239|M.thermoresistible__bu --------------------------------------------------
MSMEG_6216|M.smegmatis_MC2_155 MRPGPDGGFAPYPPPQAYP-------------------------------
MAB_0392c|M.abscessus_ATCC_199 MSNDEGGVTPSPLPPGPSPAYPPP-----------APGYPPAGTAGYP--
MLBr_01334|M.leprae_Br4923 --------------------------------------------------
Mb3714|M.bovis_AF2122/97 YGPPL-GYPAAPPGCGPPPGYG-PPLGYGPPLAPGAVKPGIIPLRPLTLS
Rv3689|M.tuberculosis_H37Rv YGPPL-GYPAAPPGCGPPPGYG-PPLGYGPPVAPGAVKPGIIPLRPLTLS
MMAR_5199|M.marinum_M YGPPP-GYGPPPPGYGPPPGYGPPPPGYGPPLVPGAVKPGIIPLRPLTLS
MUL_4272|M.ulcerans_Agy99 YAPPPPGYGPPP-GYGPPPGYGPPPPGYGPPLVPGAVKPGIIPLRPLTLS
MAV_0415|M.avium_104 YGPPP---TYPPPGYPPAPAFG-PPPGYG------VLKPGIIPLRPLTLG
Mflv_1340|M.gilvum_PYR-GCK WQPP----GYGAPGYPPPYGGP------------PVLKPGVVPLRPLTLS
Mvan_5452|M.vanbaalenii_PYR-1 WQPPGYAPGYGAPGYPPQFGLP------------PVIKPGVVPLRPLTLS
TH_3239|M.thermoresistible__bu -------------VNPMAPMRQ------------TALKPGVIPLRPLTLS
MSMEG_6216|M.smegmatis_MC2_155 ----------VHPGYASAPGFG-------------APVPGIVALRPLSLS
MAB_0392c|M.abscessus_ATCC_199 --PPGFAYQPPPPGYQNPSAVP-----YWVTPEPPALKPGVIPLRPLDLS
MLBr_01334|M.leprae_Br4923 --------MSEPQGSDPGKQWQ---------------SPGEG-VENHSSD
** :. .
Mb3714|M.bovis_AF2122/97 DIFNGAVGYIRANPKATLGLTAMVVVTLQIISLVALFGPMTAFGDIVTG-
Rv3689|M.tuberculosis_H37Rv DIFNGAVGYIRANPKATLGLTAMVVVTLQIISLVALFGPMTAFGDIVTG-
MMAR_5199|M.marinum_M DIFNGAVGYIRANPKATLGLTAIVVVVMQVITLLATIGPLEAASRFDT--
MUL_4272|M.ulcerans_Agy99 DIFNGAVGYIRANPKATLGLTAIVVVVMQVITLLAAIGPLEAASRFDT--
MAV_0415|M.avium_104 DIFNGAVGYIRANPKATLGLTAIVVIAMQIITKAAVLGPLAAYGRFTGD-
Mflv_1340|M.gilvum_PYR-GCK DIFNGAVAYVRANPKATLGLTTIVVVAAQILSLVLSLVPFTFTDMVADGL
Mvan_5452|M.vanbaalenii_PYR-1 DIFNGAVAYIRTNPKATLGLTAIVVIASQIVALLLSLWPFAFTGQVASTL
TH_3239|M.thermoresistible__bu DIFNGAVAYIRTNPKATLGLTAIVVVVAQLLALVLQIGSLAATGDLVSSV
MSMEG_6216|M.smegmatis_MC2_155 DIFNGAVAYIRRNPKATLGLTTIVVVLAQLVTLLLQVGPLAAMGGLGSEV
MAB_0392c|M.abscessus_ATCC_199 SLYNGAIAAIRANPKTTLGLTAIVVIVSQLLIFGIQAAPATAVLTGAASF
MLBr_01334|M.leprae_Br4923 QPTQAASPWQQQPSTQDSTWHPPAYASPECYNYPQLTEPVYPHQYPSATP
. :.* : .. . . : .
Mb3714|M.bovis_AF2122/97 ---EPDELTGAVVGGWSASFGASLLVSWLAGVLLSGMLTVIVGRAVFGSP
Rv3689|M.tuberculosis_H37Rv ---EPDELTGAVVGGWSASFGASLLVSWLAGVLLSGMLTVIVGRAVFGSP
MMAR_5199|M.marinum_M ---HPSELSWGVVGAWTGSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSP
MUL_4272|M.ulcerans_Agy99 ---HPSELSWGVVGAWTGSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSP
MAV_0415|M.avium_104 ---RSDELTAGVLGAWSVSVGAGVLVGWLGGMLLSGMLTVIVGRAVFGSS
Mflv_1340|M.gilvum_PYR-GCK ---GEDEASVQVIVGWVASSLAGGIATALAATVLAGMLTVVIGRSVFGAG
Mvan_5452|M.vanbaalenii_PYR-1 ---DGDEASTEVLVSWMASSLATAITTGLSTTLLSGLLTVVIGRSVFGAD
TH_3239|M.thermoresistible__bu ---RGDDVSTVGLSWADLASVTTAVANTLALLVLSGMLTVVIGRAVFGAG
MSMEG_6216|M.smegmatis_MC2_155 ---QGEAPSTGAVAMFSGATLAGVLVTQLASVLLTGMLTVIIGRSIFGGT
MAB_0392c|M.abscessus_ATCC_199 DKNTEDSFGAAFGLGYIGGQLIGAVVTSLVTIILSGMLTVTIGRSVFGER
MLBr_01334|M.leprae_Br4923 -----------------GYGQPGYFGAQFSQCGIPGQYPQSGSPGQYGPP
. : :.* . . . :*
Mb3714|M.bovis_AF2122/97 ITVGEAWAKVRGRLLALFGLALLEAAGVVAVLGLAVVILSGVAAAANEAA
Rv3689|M.tuberculosis_H37Rv ITVGEAWAKVRGRLLALFGLALLEAAGVVAVLGLAVVILSGVAAAANEAA
MMAR_5199|M.marinum_M ITISEAWARVRGRILALIGLALLEGAGLVALAGLVVVILVGVAAAANGAT
MUL_4272|M.ulcerans_Agy99 ITISEAWARVRGRILALIGLALLEGAGLVALAGLVVVILVGVAAAANGAT
MAV_0415|M.avium_104 ITVGETWTKIRGRLPALLGLALLEAVVVAAIAGLVVVVIAILAAIGNAAA
Mflv_1340|M.gilvum_PYR-GCK ITVGEAWKRLRPRFWPLIGFTVLKMLVFLVGLVLVVGIIGATGALTTGVV
Mvan_5452|M.vanbaalenii_PYR-1 ITIGEAWRRLRPRLWALIGFTVLKTLALIVWFGVVLLIVVLAVAVIDGPA
TH_3239|M.thermoresistible__bu ITISEAWERLRGRLWALIGFSVLELLAVVV-IVVLAVVMGAALAAAGGAG
MSMEG_6216|M.smegmatis_MC2_155 VTIGQAWERLRGRLLALIGLTLLEAVVLLAVVLVVIGLIAAAGAVGGAVA
MAB_0392c|M.abscessus_ATCC_199 TTIKEAWQRAKPRIWALLGVAVVELVLFAVVLGFGVAVVVGLALTVGPAG
MLBr_01334|M.leprae_Br4923 GQYGPPGQYSQ----QFQPYEQPGTKGFVALIGSIAGVIG----------
. : : . . ::
Mb3714|M.bovis_AF2122/97 AALLGFPLLLVVGVSLAYLYVVLLFAPVLIVLERLPIVEAITRSFALVRH
Rv3689|M.tuberculosis_H37Rv AALLGFPLLLVVGVSLAYLYVVLLFAPVLIVLERLPIVEAITRSFALVRH
MMAR_5199|M.marinum_M AALLGFPLVLLVGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFALVTG
MUL_4272|M.ulcerans_Agy99 AALLGFPLVLLVGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFALVTG
MAV_0415|M.avium_104 AVVLGIPLVLTVIAVLVYLYTVVLFAPVLIVLERLPVLDAITRSFRLVRR
Mflv_1340|M.gilvum_PYR-GCK AFAVAIPLVLAAVLAAVWLSVMLTFAPVIIVLERRDIVTAVKRSFTLIKA
Mvan_5452|M.vanbaalenii_PYR-1 AFLIAAPLVLASILAAVWVSVMLTFAPAVIVLERRDIVTSVKRSFALIKS
TH_3239|M.thermoresistible__bu AGALIVLLFLGTVALLAYLATVLSFGPPVIVLERLGVFAAIARSFGLVRN
MSMEG_6216|M.smegmatis_MC2_155 AFVMGVPLVLAAVLGALFGLTVLLFAPVLIVLERLDVFAAIARSFALVKT
MAB_0392c|M.abscessus_ATCC_199 AIPAGLLLALAYFLFYLYLIPVFSLVPSVLILEQQSVFGAIGRSVSLVRK
MLBr_01334|M.leprae_Br4923 ------VLIFAAILVTGFLWPAWLVTTKLDVN---KAQASVQQVLTDETN
* : : . . : : :: : .
Mb3714|M.bovis_AF2122/97 GFWRVLGIRLLTVLVVGVVGNAIAAPFMIVGEIVTAV-TASDGSVTMRLV
Rv3689|M.tuberculosis_H37Rv GFWRVLGIRLLTVLVVGVVGNAIAAPFMIVGEIVTAV-TASDGSVTMRLV
MMAR_5199|M.marinum_M GFWRVLGIRLLTAIVVGLVGGAISAPFGIVGQILLGA-TASEGSTGMFLV
MUL_4272|M.ulcerans_Agy99 GFWRVLGIRLLTAIVVGLVGGAISAPFGIVGQILLGA-TASEGSTGMFLV
MAV_0415|M.avium_104 GFWRVLGIRALAFLVTAVVANAVAVPFSIVGQVFQIS-SSG----TAFLI
Mflv_1340|M.gilvum_PYR-GCK DFWRVFGIWLLAAIVAQFIAGAVSIPFTLGGQIAFSA-SAT---TASAML
Mvan_5452|M.vanbaalenii_PYR-1 DFWRVFGIWLLAAIVAQFIAGAVSIPFSIGGQAVLTA-SAT---TTAAMI
TH_3239|M.thermoresistible__bu SFWRVFGIRLLAWLVAGVISVAVAVPFSVAGGLFGLS-ADS---SALAII
MSMEG_6216|M.smegmatis_MC2_155 GFWRVLGIWLLASLVASVIASAVGAPFSIVGQLLTMS-PDG---VGMSIV
MAB_0392c|M.abscessus_ATCC_199 GFWRLLGILVLTGFIVGFVSMIIGMPFILVGEVAAFAGSDPNNLGPKMLL
MLBr_01334|M.leprae_Br4923 GYG--------AKNVKDVKCNNGADPTVKKGDTFDCS-------------
.: : : . . * *
Mb3714|M.bovis_AF2122/97 GATLSAIGVTIGQIVTAPFSAGVVVLLYTDRRIRAEAFDLVLQTGLEAGP
Rv3689|M.tuberculosis_H37Rv GATLSAIGVTIGQIVTAPFSAGVVVLLYTDRRIRAEAFDLVLQTGLEAGP
MMAR_5199|M.marinum_M GMTLSSIGSAISQIITAPFTAGVVVLLYTDRRMRAEAFDLVLQT----GA
MUL_4272|M.ulcerans_Agy99 GMTLSSIGSAISQIITAPFTAGVVVLLYTDRRMRAEAFDLVLQT----GA
MAV_0415|M.avium_104 STAILSVGAAIGEIITAPFNAGVIVLLYTDRRMRAEAFDLLQS-----GA
Mflv_1340|M.gilvum_PYR-GCK AFALFAIGGAIGQIITGPFTAGVSVLQYADRRIRAEAFDLVLQT-GAT--
Mvan_5452|M.vanbaalenii_PYR-1 SMVLFSVGGAVGQIITGPFSAGVTVLQYTDRRIRAEAFDLVLQT-GAA--
TH_3239|M.thermoresistible__bu SLTLIAIGGAVGQIITTPFNAGVIVLLYADRRIRAEAFDLVLQT-GAT--
MSMEG_6216|M.smegmatis_MC2_155 GLVLVAVGGTIGQIVTAPFAAGVDVLLYTDRRIRAEAFDLVLRT-GAYTP
MAB_0392c|M.abscessus_ATCC_199 IFALAAVGAVIAQIISLPFKAAVNVLLYTDQRMRTEALDLVLQT-EARTR
MLBr_01334|M.leprae_Br4923 -------------VSIDGMQKRVTVTFQDDKGTYEVGRPQ----------
: : * * *: .
Mb3714|M.bovis_AF2122/97 AGGPAPVESTDNLWLTRPF---------
Rv3689|M.tuberculosis_H37Rv AGGPAPVESTDNLWLTRPF---------
MMAR_5199|M.marinum_M AGGPAAVESTDNLWLTRPL---------
MUL_4272|M.ulcerans_Agy99 AGGPAAVESTDTLWLTRPL---------
MAV_0415|M.avium_104 AQGSYAAASTDNLWLTRPR---------
Mflv_1340|M.gilvum_PYR-GCK AGPYAPADSTDDLWLTR-----------
Mvan_5452|M.vanbaalenii_PYR-1 AGPQAPADSTDDLWLTGPR---------
TH_3239|M.thermoresistible__bu AGP-AHAESTDQLWLPRPTTPWAAHHPR
MSMEG_6216|M.smegmatis_MC2_155 APPAAPAESTDQLWLVRHF---------
MAB_0392c|M.abscessus_ATCC_199 ERLGQPGIDPDSLWLPMRPPVQV-----
MLBr_01334|M.leprae_Br4923 ----------------------------