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M. thermoresistible (build 8) TH_3239 (-)

annotation: putative putative conserved transmembrane protein
coordinates: 3296963 - 3297988
length: 342

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3239--100% (342)putative putative conserved transmembrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3714-1e-8753.89% (334) transmembrane protein
M. gilvum PYR-GCKMflv_1340-2e-9056.66% (323) putative transmembrane protein
M. tuberculosis H37RvRv3689-2e-8753.89% (334) transmembrane protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_0392c-2e-6445.18% (332) hypothetical protein MAB_0392c
M. marinum MMMAR_5199-6e-8653.73% (335) hypothetical protein MMAR_5199
M. avium 104MAV_0415-6e-8755.59% (322) hypothetical protein MAV_0415
M. smegmatis MC2 155MSMEG_6216-4e-9257.63% (321) integral membrane protein
M. ulcerans Agy99MUL_4272-5e-8653.73% (335) hypothetical protein MUL_4272
M. vanbaalenii PYR-1Mvan_5452-4e-9356.62% (325) putative transmembrane protein

CLUSTAL 2.0.9 multiple sequence alignment


Mb3714|M.bovis_AF2122/97            MHKRYAPQRPKPDTETYIEKCTDRRQDGGHDERRQLLRPVSMLPPGYPVE
Rv3689|M.tuberculosis_H37Rv         MHKRYAPQRPKPDTETYIEKCTDRRQDGGHDERRQLLRPVSMLPPGYPVE
MMAR_5199|M.marinum_M               --------------------------------------MSTLPPPGYPVE
MUL_4272|M.ulcerans_Agy99           --------------------------------------MSTLPPPGYPVE
MAV_0415|M.avium_104                -------------------MCATLRAG----ARVNVVKWSGRRQDGAHDE
MSMEG_6216|M.smegmatis_MC2_155      -----------------------------------------MRP------
TH_3239|M.thermoresistible__bu      --------------------------------------------------
Mflv_1340|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_5452|M.vanbaalenii_PYR-1       --------------------------------------------------
MAB_0392c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb3714|M.bovis_AF2122/97            PPPVAPGYAPAGYPP--YPATPPGYGPP-------GYGAPP-SYGPPP-G
Rv3689|M.tuberculosis_H37Rv         PPPVAPGYAPAGYPP--YPATPPGYGPP-------GYGAPP-SYGPPP-G
MMAR_5199|M.marinum_M               PNSGAPGYEAAGYPPSGYADPPPAYGPPPAYGPPPGYGAPPPGYGPPPPG
MUL_4272|M.ulcerans_Agy99           PNSGAPGYEAAGYPPSGYADPPPAYGPPPAYGPPPGYGAPPPGYGPPP-G
MAV_0415|M.avium_104                PPVHEPRGSVSAPPPGYPVGPPPAYGSQSHYG--TQYGAQYPGQYGVH--
MSMEG_6216|M.smegmatis_MC2_155      ----GPDGGFAPYPP------PQAYPVH----------------------
TH_3239|M.thermoresistible__bu      --------------------------------------------------
Mflv_1340|M.gilvum_PYR-GCK          MTYDAGGYGPAGFPP-------PRYP-------------PPPGYGPPPG-
Mvan_5452|M.vanbaalenii_PYR-1       MTYNAGGYGPAGPPP-------PGYPAPGY------PGYPPAGYGAPPQY
MAB_0392c|M.abscessus_ATCC_199      MSNDEGGVTPSPLPP----GPSPAYPPP-------APGYPPAGTAGYP--
                                                                                      

Mb3714|M.bovis_AF2122/97            YGPPL-GYPAAPPGCGPPPGYG-PPLGYGPPLAPGAVKPGIIPLRPLTLS
Rv3689|M.tuberculosis_H37Rv         YGPPL-GYPAAPPGCGPPPGYG-PPLGYGPPVAPGAVKPGIIPLRPLTLS
MMAR_5199|M.marinum_M               YGPPP-GYGPPPPGYGPPPGYGPPPPGYGPPLVPGAVKPGIIPLRPLTLS
MUL_4272|M.ulcerans_Agy99           YAPPPPGYGPPP-GYGPPPGYGPPPPGYGPPLVPGAVKPGIIPLRPLTLS
MAV_0415|M.avium_104                YGPPP---TYPPPGYPPAPAFG-PPPGYG------VLKPGIIPLRPLTLG
MSMEG_6216|M.smegmatis_MC2_155      ------------PGYASAPGFG-------------APVPGIVALRPLSLS
TH_3239|M.thermoresistible__bu      --------------VNPMAPMR-----------QTALKPGVIPLRPLTLS
Mflv_1340|M.gilvum_PYR-GCK          WQPP----GYGAPGYPPPYGGP------------PVLKPGVVPLRPLTLS
Mvan_5452|M.vanbaalenii_PYR-1       WQPPGYAPGYGAPGYPPQFGLP------------PVIKPGVVPLRPLTLS
MAB_0392c|M.abscessus_ATCC_199      --PPGFAYQPPPPGYQNPSAVP-----YWVTPEPPALKPGVIPLRPLDLS
                                                                       .  **::.**** *.

Mb3714|M.bovis_AF2122/97            DIFNGAVGYIRANPKATLGLTAMVVVTLQIISLVALFGPMTA--FGDIVT
Rv3689|M.tuberculosis_H37Rv         DIFNGAVGYIRANPKATLGLTAMVVVTLQIISLVALFGPMTA--FGDIVT
MMAR_5199|M.marinum_M               DIFNGAVGYIRANPKATLGLTAIVVVVMQVITLLATIGPLEA--ASRFDT
MUL_4272|M.ulcerans_Agy99           DIFNGAVGYIRANPKATLGLTAIVVVVMQVITLLAAIGPLEA--ASRFDT
MAV_0415|M.avium_104                DIFNGAVGYIRANPKATLGLTAIVVIAMQIITKAAVLGPLAA--YGRFTG
MSMEG_6216|M.smegmatis_MC2_155      DIFNGAVAYIRRNPKATLGLTTIVVVLAQLVTLLLQVGPLAA--MGGLGS
TH_3239|M.thermoresistible__bu      DIFNGAVAYIRTNPKATLGLTAIVVVVAQLLALVLQIGSLAA--TGDLVS
Mflv_1340|M.gilvum_PYR-GCK          DIFNGAVAYVRANPKATLGLTTIVVVAAQILSLVLSLVPFTF--TDMVAD
Mvan_5452|M.vanbaalenii_PYR-1       DIFNGAVAYIRTNPKATLGLTAIVVIASQIVALLLSLWPFAF--TGQVAS
MAB_0392c|M.abscessus_ATCC_199      SLYNGAIAAIRANPKTTLGLTAIVVIVSQLLIFGIQAAPATAVLTGAASF
                                    .::***:. :* ***:*****::**:  *::       .      .    

Mb3714|M.bovis_AF2122/97            GEPDELT-GAVVGG-WSASFGASLLVSWLAGVLLSGMLTVIVGRAVFGSP
Rv3689|M.tuberculosis_H37Rv         GEPDELT-GAVVGG-WSASFGASLLVSWLAGVLLSGMLTVIVGRAVFGSP
MMAR_5199|M.marinum_M               -HPSELS-WGVVGA-WTGSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSP
MUL_4272|M.ulcerans_Agy99           -HPSELS-WGVVGA-WTGSAAAGLLVSWLGGMLLSGILTVVVGRAVFGSP
MAV_0415|M.avium_104                DRSDELT-AGVLGA-WSVSVGAGVLVGWLGGMLLSGMLTVIVGRAVFGSS
MSMEG_6216|M.smegmatis_MC2_155      EVQGEAPSTGAVAM-FSGATLAGVLVTQLASVLLTGMLTVIIGRSIFGGT
TH_3239|M.thermoresistible__bu      SVRGDDVSTVGLSW-ADLASVTTAVANTLALLVLSGMLTVVIGRAVFGAG
Mflv_1340|M.gilvum_PYR-GCK          GLGEDEASVQVIVG-WVASSLAGGIATALAATVLAGMLTVVIGRSVFGAG
Mvan_5452|M.vanbaalenii_PYR-1       TLDGDEASTEVLVS-WMASSLATAITTGLSTTLLSGLLTVVIGRSVFGAD
MAB_0392c|M.abscessus_ATCC_199      DKNTEDSFGAAFGLGYIGGQLIGAVVTSLVTIILSGMLTVTIGRSVFGER
                                        :      .      .     :.  *   :*:*:*** :**::**  

Mb3714|M.bovis_AF2122/97            ITVGEAWAKVRGRLLALFGLALLEAAGVVAVLGLAVVILSGVAAAANEAA
Rv3689|M.tuberculosis_H37Rv         ITVGEAWAKVRGRLLALFGLALLEAAGVVAVLGLAVVILSGVAAAANEAA
MMAR_5199|M.marinum_M               ITISEAWARVRGRILALIGLALLEGAGLVALAGLVVVILVGVAAAANGAT
MUL_4272|M.ulcerans_Agy99           ITISEAWARVRGRILALIGLALLEGAGLVALAGLVVVILVGVAAAANGAT
MAV_0415|M.avium_104                ITVGETWTKIRGRLPALLGLALLEAVVVAAIAGLVVVVIAILAAIGNAAA
MSMEG_6216|M.smegmatis_MC2_155      VTIGQAWERLRGRLLALIGLTLLEAVVLLAVVLVVIGLIAAAGAVGGAVA
TH_3239|M.thermoresistible__bu      ITISEAWERLRGRLWALIGFSVLELLAVVVIVVLAVVMGAALAAAGGAGA
Mflv_1340|M.gilvum_PYR-GCK          ITVGEAWKRLRPRFWPLIGFTVLKMLVFLVGLVLVVGIIGATGALTTGVV
Mvan_5452|M.vanbaalenii_PYR-1       ITIGEAWRRLRPRLWALIGFTVLKTLALIVWFGVVLLIVVLAVAVIDGPA
MAB_0392c|M.abscessus_ATCC_199      TTIKEAWQRAKPRIWALLGVAVVELVLFAVVLGFGVAVVVGLALTVGPAG
                                     *: ::* : : *: .*:*.::::   . .   . : :            

Mb3714|M.bovis_AF2122/97            AALLGFPLLLVVGVSLAYLYVVLLFAPVLIVLERLPIVEAITRSFALVRH
Rv3689|M.tuberculosis_H37Rv         AALLGFPLLLVVGVSLAYLYVVLLFAPVLIVLERLPIVEAITRSFALVRH
MMAR_5199|M.marinum_M               AALLGFPLVLLVGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFALVTG
MUL_4272|M.ulcerans_Agy99           AALLGFPLVLLVGLLVAYLYTVLMFAPVLIVLERLPLVDAITRSFALVTG
MAV_0415|M.avium_104                AVVLGIPLVLTVIAVLVYLYTVVLFAPVLIVLERLPVLDAITRSFRLVRR
MSMEG_6216|M.smegmatis_MC2_155      AFVMGVPLVLAAVLGALFGLTVLLFAPVLIVLERLDVFAAIARSFALVKT
TH_3239|M.thermoresistible__bu      GALI-VLLFLGTVALLAYLATVLSFGPPVIVLERLGVFAAIARSFGLVRN
Mflv_1340|M.gilvum_PYR-GCK          AFAVAIPLVLAAVLAAVWLSVMLTFAPVIIVLERRDIVTAVKRSFTLIKA
Mvan_5452|M.vanbaalenii_PYR-1       AFLIAAPLVLASILAAVWVSVMLTFAPAVIVLERRDIVTSVKRSFALIKS
MAB_0392c|M.abscessus_ATCC_199      AIPAGLLLALAYFLFYLYLIPVFSLVPSVLILEQQSVFGAIGRSVSLVRK
                                    .      * *       :   :. : * :::**:  :. :: **. *:  

Mb3714|M.bovis_AF2122/97            GFWRVLGIRLLTVLVVGVVGNAIAAPFMIVGEIVTAV-TASDGSVTMRLV
Rv3689|M.tuberculosis_H37Rv         GFWRVLGIRLLTVLVVGVVGNAIAAPFMIVGEIVTAV-TASDGSVTMRLV
MMAR_5199|M.marinum_M               GFWRVLGIRLLTAIVVGLVGGAISAPFGIVGQILLGA-TASEGSTGMFLV
MUL_4272|M.ulcerans_Agy99           GFWRVLGIRLLTAIVVGLVGGAISAPFGIVGQILLGA-TASEGSTGMFLV
MAV_0415|M.avium_104                GFWRVLGIRALAFLVTAVVANAVAVPFSIVGQVFQIS-SSG----TAFLI
MSMEG_6216|M.smegmatis_MC2_155      GFWRVLGIWLLASLVASVIASAVGAPFSIVGQLLTMS-PDG---VGMSIV
TH_3239|M.thermoresistible__bu      SFWRVFGIRLLAWLVAGVISVAVAVPFSVAGGLFGLS-ADS---SALAII
Mflv_1340|M.gilvum_PYR-GCK          DFWRVFGIWLLAAIVAQFIAGAVSIPFTLGGQIAFSA-SAT---TASAML
Mvan_5452|M.vanbaalenii_PYR-1       DFWRVFGIWLLAAIVAQFIAGAVSIPFSIGGQAVLTA-SAT---TTAAMI
MAB_0392c|M.abscessus_ATCC_199      GFWRLLGILVLTGFIVGFVSMIIGMPFILVGEVAAFAGSDPNNLGPKMLL
                                    .***::**  *: ::. .:.  :. ** : *       .         ::

Mb3714|M.bovis_AF2122/97            GATLSAIGVTIGQIVTAPFSAGVVVLLYTDRRIRAEAFDLVLQTGLEAGP
Rv3689|M.tuberculosis_H37Rv         GATLSAIGVTIGQIVTAPFSAGVVVLLYTDRRIRAEAFDLVLQTGLEAGP
MMAR_5199|M.marinum_M               GMTLSSIGSAISQIITAPFTAGVVVLLYTDRRMRAEAFDLVLQT----GA
MUL_4272|M.ulcerans_Agy99           GMTLSSIGSAISQIITAPFTAGVVVLLYTDRRMRAEAFDLVLQT----GA
MAV_0415|M.avium_104                STAILSVGAAIGEIITAPFNAGVIVLLYTDRRMRAEAFDLLQS-----GA
MSMEG_6216|M.smegmatis_MC2_155      GLVLVAVGGTIGQIVTAPFAAGVDVLLYTDRRIRAEAFDLVLRTG-AYTP
TH_3239|M.thermoresistible__bu      SLTLIAIGGAVGQIITTPFNAGVIVLLYADRRIRAEAFDLVLQT----GA
Mflv_1340|M.gilvum_PYR-GCK          AFALFAIGGAIGQIITGPFTAGVSVLQYADRRIRAEAFDLVLQTG---AT
Mvan_5452|M.vanbaalenii_PYR-1       SMVLFSVGGAVGQIITGPFSAGVTVLQYTDRRIRAEAFDLVLQTG---AA
MAB_0392c|M.abscessus_ATCC_199      IFALAAVGAVIAQIISLPFKAAVNVLLYTDQRMRTEALDLVLQTEAR-TR
                                      .: ::* .:.:*:: ** *.* ** *:*:*:*:**:**:         

Mb3714|M.bovis_AF2122/97            AGGPAPVESTDNLWLTRPF---------
Rv3689|M.tuberculosis_H37Rv         AGGPAPVESTDNLWLTRPF---------
MMAR_5199|M.marinum_M               AGGPAAVESTDNLWLTRPL---------
MUL_4272|M.ulcerans_Agy99           AGGPAAVESTDTLWLTRPL---------
MAV_0415|M.avium_104                AQGSYAAASTDNLWLTRPR---------
MSMEG_6216|M.smegmatis_MC2_155      APPAAPAESTDQLWLVRHF---------
TH_3239|M.thermoresistible__bu      TAGPAHAESTDQLWLPRPTTPWAAHHPR
Mflv_1340|M.gilvum_PYR-GCK          AGPYAPADSTDDLWLTR-----------
Mvan_5452|M.vanbaalenii_PYR-1       AGPQAPADSTDDLWLTGPR---------
MAB_0392c|M.abscessus_ATCC_199      ERLGQPGIDPDSLWLPMRPPVQV-----
                                            ..* ***