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VTILAAFSASGHARAPLYLAAQIARTTGDNVLAAAVIERPWPPRGDPVEKEYLDYVGRQAAHALDSAAAV LPATIEFSTLVHESTSVPKGLMELAASHRAQIVVVGSSSSGLLGRVALGSVTERLVHTAQVPVAIAPRGY AQGSGKIRRLTAAYGGEADVNGLIPAAAQLAKDWSTLLRIVSFTVRNVAAFSGRIESAAEDLVVQQWSRR THDDIVRLLDSVRADVRNDGPLDDVDVVVGTGADWNTAVQSVPWEAGDMLLLGSGAAAQSAQVFLGSAAA RILRNCPVPVMVVPRYEG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5474 | - | - | 100% (298) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_1411 | - | 2e-44 | 32.78% (302) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_1624 | - | 1e-30 | 31.54% (298) | universal stress protein family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2346c | - | 2e-34 | 30.87% (298) | hypothetical protein Mb2346c |
| M. gilvum PYR-GCK | Mflv_1999 | - | 1e-95 | 59.40% (298) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv2319c | - | 2e-34 | 30.87% (298) | hypothetical protein Rv2319c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3843 | - | 3e-39 | 31.13% (302) | hypothetical protein MAB_3843 |
| M. marinum M | MMAR_3620 | - | 1e-36 | 29.29% (297) | hypothetical protein MMAR_3620 |
| M. avium 104 | MAV_2494 | - | 3e-05 | 46.51% (43) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 2e-05 | 37.80% (82) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_1245 | - | 3e-37 | 29.97% (297) | hypothetical protein MUL_1245 |
| M. vanbaalenii PYR-1 | Mvan_1573 | - | 4e-27 | 32.51% (283) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5474|M.smegmatis_MC2_155 -----------------------MTILAAFSASGHARAPLYLAAQIARTT
Mflv_1999|M.gilvum_PYR-GCK -----------------------MTIIAGFSASGQGPAPLHLAAQLARCT
Mb2346c|M.bovis_AF2122/97 -----------------------MTIVVGYLAGKVGPSALHLAVRVARMH
Rv2319c|M.tuberculosis_H37Rv -----------------------MTIVVGYLAGKVGPSALHLAVRVARMH
MMAR_3620|M.marinum_M -----------------------MTVVVGYLAGRVGPSALHLAVRAARTL
MUL_1245|M.ulcerans_Agy99 -----------------------MTVVVGYLAGRVGPSALHLAVRAARTL
MAB_3843|M.abscessus_ATCC_1997 -----------------------MTVVVGYLSGKGGKGALHLAVESARVL
MAV_2494|M.avium_104 -----------------------MRTIRTAAAFSSGLYLRVVGFPGDCSF
TH_2494|M.thermoresistible__bu VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRN-LQLTLVHVMTATSI
Mvan_1573|M.vanbaalenii_PYR-1 -----------------------MHLTVGYLATPTGDDGVALASALARTF
: : :
MSMEG_5474|M.smegmatis_MC2_155 GDNVLAAAVIERPWPP----RGDPVEKEYLDYVGRQAAHALDSAAAVLPA
Mflv_1999|M.gilvum_PYR-GCK GERIVAVAIVERQWPQ----NADPLEDEYLNYVGAQAQKSLKEMVDKLPG
Mb2346c|M.bovis_AF2122/97 KTSLTVATIVRRHWPTPSLARVDAEYELWSEQLAAASAREAQRYLRRLAD
Rv2319c|M.tuberculosis_H37Rv KTSLTVATIVRRHWPTPSLARVDAEYELWSEQLAAASAREAQRYLRRLAD
MMAR_3620|M.marinum_M DTSLTVATILTKPWLTPPLAKG--DYSEWAEQVAEDSEKEAHRYLRTVAT
MUL_1245|M.ulcerans_Agy99 DTSLTVATILTKPWLTPPLAKG--DYSEWAEQVAEDSEKEAHRYLRTVAT
MAB_3843|M.abscessus_ATCC_1997 ETSLTVTTVVPKPWTTLSKAKIDAEYAQWAQKLSDDSKSEATAYLEKIGA
MAV_2494|M.avium_104 G-------------------------------IAPSSFPRSGAS------
TH_2494|M.thermoresistible__bu GAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPAG
Mvan_1573|M.vanbaalenii_PYR-1 DATVDVVIVVRHELPDG----HPGRAEYQQMLVNLGEQWAARAVAALAAD
:
MSMEG_5474|M.smegmatis_MC2_155 TIEFSTLVHESTSVPKGLMELAASHRAQIVVVGSSSSGLLGRVALGSVTE
Mflv_1999|M.gilvum_PYR-GCK DLDVWRMVHQAESVPSGLTELAEEMNADVVVVGSSSSGLLGRIALGSVTD
Mb2346c|M.bovis_AF2122/97 GIEVSYHHRAHRSVSAGLLDVVEELEAEVLVLGSFPSGRRARVLIGSTAD
Rv2319c|M.tuberculosis_H37Rv GIEVSYHHRAHRSVSAGLLDVVEELEAEVLVLGSFPSGRRARVLIGSTAD
MMAR_3620|M.marinum_M GIEVSYCHREHRSVSGGLIEVVEELDAEMLILGSFPNGRRARVLIGSTAD
MUL_1245|M.ulcerans_Agy99 GIEVSYCHREHRSVSGGLIEVVEELDAQMLILGSFPNGRRARVLIGSTAD
MAB_3843|M.abscessus_ATCC_1997 GIDVTFHNVAHRSVSGGLLEAVEASDADVLVVGSASEGRLGQVVLGSTGD
MAV_2494|M.avium_104 ----RISRAIHYSAPVPALLELSG-AVRMLVLGSAGHGLLARGLLGSVSS
TH_2494|M.thermoresistible__bu DDAVRVVTGVVRAAPVPTLVDASK-QAKLVAVGSRGQGPLRRVLLGSVSS
Mvan_1573|M.vanbaalenii_PYR-1 GVTAESSAIVADSFAQALVEFAEEKSSDLIVVGGARDGFFGRHTIGPVTG
: . :: :*. * : :*..
MSMEG_5474|M.smegmatis_MC2_155 RLVHTAQVPVAIAPRGYA-QGSGKIRRLTAAYGGEADVNGLIPAAAQLAK
Mflv_1999|M.gilvum_PYR-GCK RLVHTAAVPVAIAPRGYP-LQDSRIERLTVAYGGHADEGGLVAAGAELAR
Mb2346c|M.bovis_AF2122/97 RLLHSSPVPVAITPRRYR-CYTDRLTRLSCGYSATSGSVDVVRRCGHLAS
Rv2319c|M.tuberculosis_H37Rv RLLHSSPVPVAITPRRYR-CYTDRLTRLSCGYSATSGSVDVVRRCGHLAS
MMAR_3620|M.marinum_M WVLHSSPVPVAISPRQYH-SRTDRLTRITCGYAATTDSVEVVRRCAELAR
MUL_1245|M.ulcerans_Agy99 WVLHSSPVPVAISPRQYH-SRTDRLTRITCGYAATTDSVEVVRRCAELAR
MAB_3843|M.abscessus_ATCC_1997 RLLHSSPVPLAISPRGYRGSRAGTVSRVTCGYPGTEDAVDVVQQAVRLTQ
MAV_2494|M.avium_104 AVVRHANCPVAVVRD--EELPDPHSAPVLLGTDGSPASELATEIAFDEAS
TH_2494|M.thermoresistible__bu GLVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEEAS
Mvan_1573|M.vanbaalenii_PYR-1 ALLHSSSIPVALAPRGYAEDPDEHFLAVTAAVPSKPGDDNPLPFAIALAG
::: : *:*: : . . :
MSMEG_5474|M.smegmatis_MC2_155 DWSTLLRIVSFTVRNVAAFSGRIESAAEDLVVQQWSRRTHDDIVRLLDSV
Mflv_1999|M.gilvum_PYR-GCK RWSATLRIASFTVRPVTMFSGAIETSAEDLVVQQWVRRTQEKIAAQLEAV
Mb2346c|M.bovis_AF2122/97 RYGVPMRVITFAVRGRTMYPPEVGLHAEASVLEAWAAQARELLEKLRING
Rv2319c|M.tuberculosis_H37Rv RYGVPMRVITFAVRGRTMYPPEVGLHAEASVLEAWAAQARELLEKLRING
MMAR_3620|M.marinum_M QYGVPLRVITFAVRGRTMYPPEVGLHAEALVLEAWAEQARGMLEMLQKDG
MUL_1245|M.ulcerans_Agy99 QYGVPLRVITFAVRVRTMYPPEVGLHAEALVLEAWAEQARGMLEMLQKDG
MAB_3843|M.abscessus_ATCC_1997 RLHAPLRVVTFAVRGRTMLTAGVGPEAEDAVLASWVTQSEEALSELRQAG
MAV_2494|M.avium_104 RRGVDLVAIHAWSDTAVTEVFEIDWPIVEAEAERHLAESLAGWQER----
TH_2494|M.thermoresistible__bu FRGVDLIALHAWSDADIADIPTLELSAVQQSAERVLSERLAGFRER----
Mvan_1573|M.vanbaalenii_PYR-1 AAGLRMRMLSLVS---AENLAEAGSAKEVRALQVAAAEENLAVAARALPD
: .
MSMEG_5474|M.smegmatis_MC2_155 RADVRNDGPLDDVDVVVGTGADWNTAVQSVPWEAGDMLLLGSGAAAQSAQ
Mflv_1999|M.gilvum_PYR-GCK RSGVDT----LDAEVVIGAGATWRDAVEAIDWGSGDVLVLGSGAAGQVAQ
Mb2346c|M.bovis_AF2122/97 -------VVSEDVVLQVVTGNGWAQALDAADWQDGEILALGTSPFGDVAR
Rv2319c|M.tuberculosis_H37Rv -------VVSEDVVLQVVTGNGWAQALDAADWQDGEILALGTSPFGDVAR
MMAR_3620|M.marinum_M -------IVEEDAVLEVITGNGWQHALDAADWEDGEILAVGTSPRGDIAR
MUL_1245|M.ulcerans_Agy99 -------IVEEDAVLEVITGNGWQHALDAADWEDGEILAVGTSPRGDIAR
MAB_3843|M.abscessus_ATCC_1997 -------IVTADVELKVVTGDTWDDALDNAEWNDGELLVLGSRPHSAVAR
MAV_2494|M.avium_104 ---------YPDVTVHRLVARDRAAQHIISSSETAQLVVVGSHGRGGLAR
TH_2494|M.thermoresistible__bu ---------YPDVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTG
Mvan_1573|M.vanbaalenii_PYR-1 ---------APDIESLVADGMTLESALKKLRWDDGDLLVVGSSRFAAPRR
* .::: :*: .
MSMEG_5474|M.smegmatis_MC2_155 VFLGSAAARILRNCPVPVMVVPRYEG-
Mflv_1999|M.gilvum_PYR-GCK VFLGSAAARILRHSPVPTMIVPRREGL
Mb2346c|M.bovis_AF2122/97 VFLGSWSGKIIRYSPVPVLVLPG----
Rv2319c|M.tuberculosis_H37Rv VFLGSWSGKIIRYSPVPVLVLPG----
MMAR_3620|M.marinum_M VFLGSNSGKIIRHSPVPVLVLPG----
MUL_1245|M.ulcerans_Agy99 VFLGSNSGRIIRHSPVPVLVLPG----
MAB_3843|M.abscessus_ATCC_1997 VFLGSRATKIVRHSPVPVVVMPG----
MAV_2494|M.avium_104 LLLGSVSNAVLHSVRVPVIVARPPA--
TH_2494|M.thermoresistible__bu MLLGSVSRAVVNAVTTPVIVAR-----
Mvan_1573|M.vanbaalenii_PYR-1 IFLGSTAARILAGVDVPVIVVPKAE--
::*** : :: .*.::