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TVVVGYLTGKAGASPLHLAVGAARTLQTSLAVATVVPRPWMTPSPARIDAEYAQYAAQLASTSAEQARQV ISELDSELEVTFHKFAHRSVSDGLMEAVESLNAEALVLGSAADGKLGQVVVGSTADRLLHSCPVPLVVSP RGYRRPRSGGLSRITVAYPGTRDAVDVVERIAALTQRLGVTMRVVTFAVRGRSMYPPLVGLSKEDLILQE WIEQAQDSLRRLATDGVIGEDVEVVVASGSAWDEALDSIEWIEGEVLAIGTSPAGAVRRVFLGERGTKIL RYSPLPVLVLPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_1411 | - | - | 100% (293) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_5474 | - | 2e-44 | 32.78% (302) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_1624 | - | 3e-29 | 27.89% (294) | universal stress protein family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2346c | - | 2e-85 | 54.27% (293) | hypothetical protein Mb2346c |
| M. gilvum PYR-GCK | Mflv_1999 | - | 1e-50 | 33.56% (295) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv2319c | - | 2e-85 | 54.27% (293) | hypothetical protein Rv2319c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3843 | - | 3e-95 | 57.00% (293) | hypothetical protein MAB_3843 |
| M. marinum M | MMAR_3620 | - | 2e-82 | 51.88% (293) | hypothetical protein MMAR_3620 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1245 | - | 7e-81 | 50.85% (293) | hypothetical protein MUL_1245 |
| M. vanbaalenii PYR-1 | Mvan_1573 | - | 6e-26 | 29.45% (292) | UspA domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2346c|M.bovis_AF2122/97 MTIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTPSLARVD
Rv2319c|M.tuberculosis_H37Rv MTIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTPSLARVD
MMAR_3620|M.marinum_M MTVVVGYLAGRVGPSALHLAVRAARTLDTSLTVATILTKPWLTPPLAKG-
MUL_1245|M.ulcerans_Agy99 MTVVVGYLAGRVGPSALHLAVRAARTLDTSLTVATILTKPWLTPPLAKG-
MSMEG_1411|M.smegmatis_MC2_155 MTVVVGYLTGKAGASPLHLAVGAARTLQTSLAVATVVPRPWMTPSPARID
MAB_3843|M.abscessus_ATCC_1997 MTVVVGYLSGKGGKGALHLAVESARVLETSLTVTTVVPKPWTTLSKAKID
Mflv_1999|M.gilvum_PYR-GCK MTIIAGFSASGQGPAPLHLAAQLARCTGERIVAVAIVERQWPQN----AD
Mvan_1573|M.vanbaalenii_PYR-1 MHLTVGYLATPTGDDGVALASALARTFDATVDVVIVVRHELPDG-----H
* : .*: : * : ** ** : .. :: :
Mb2346c|M.bovis_AF2122/97 AEYELWSEQLAAASAREAQRYLRRLADG-IEVSYHHRAHRSVSAGLLDVV
Rv2319c|M.tuberculosis_H37Rv AEYELWSEQLAAASAREAQRYLRRLADG-IEVSYHHRAHRSVSAGLLDVV
MMAR_3620|M.marinum_M -DYSEWAEQVAEDSEKEAHRYLRTVATG-IEVSYCHREHRSVSGGLIEVV
MUL_1245|M.ulcerans_Agy99 -DYSEWAEQVAEDSEKEAHRYLRTVATG-IEVSYCHREHRSVSGGLIEVV
MSMEG_1411|M.smegmatis_MC2_155 AEYAQYAAQLASTSAEQARQVISELDSE-LEVTFHKFAHRSVSDGLMEAV
MAB_3843|M.abscessus_ATCC_1997 AEYAQWAQKLSDDSKSEATAYLEKIGAG-IDVTFHNVAHRSVSGGLLEAV
Mflv_1999|M.gilvum_PYR-GCK PLEDEYLNYVGAQAQKSLKEMVDKLPGD-LDVWRMVHQAESVPSGLTELA
Mvan_1573|M.vanbaalenii_PYR-1 PGRAEYQQMLVNLGEQWAARAVAALAADGVTAESSAIVADSFAQALVEFA
: : . : : : . *.. .* : .
Mb2346c|M.bovis_AF2122/97 EELEAEVLVLGSFPSGRRARVLIGSTADRLLHSSPVPVAITPRRYR-CYT
Rv2319c|M.tuberculosis_H37Rv EELEAEVLVLGSFPSGRRARVLIGSTADRLLHSSPVPVAITPRRYR-CYT
MMAR_3620|M.marinum_M EELDAEMLILGSFPNGRRARVLIGSTADWVLHSSPVPVAISPRQYH-SRT
MUL_1245|M.ulcerans_Agy99 EELDAQMLILGSFPNGRRARVLIGSTADWVLHSSPVPVAISPRQYH-SRT
MSMEG_1411|M.smegmatis_MC2_155 ESLNAEALVLGSAADGKLGQVVVGSTADRLLHSCPVPLVVSPRGYRRPRS
MAB_3843|M.abscessus_ATCC_1997 EASDADVLVVGSASEGRLGQVVLGSTGDRLLHSSPVPLAISPRGYRGSRA
Mflv_1999|M.gilvum_PYR-GCK EEMNADVVVVGSSSSGLLGRIALGSVTDRLVHTAAVPVAIAPRGYP-LQD
Mvan_1573|M.vanbaalenii_PYR-1 EEKSSDLIVVGGARDGFFGRHTIGPVTGALLHSSSIPVALAPRGYAEDPD
* .:: :::*. .* .: :*.. . ::*:..:*:.::** *
Mb2346c|M.bovis_AF2122/97 DRLTRLSCGYSATSGSVDVVRRCGHLASRYGVPMRVITFAVRGRTMYPPE
Rv2319c|M.tuberculosis_H37Rv DRLTRLSCGYSATSGSVDVVRRCGHLASRYGVPMRVITFAVRGRTMYPPE
MMAR_3620|M.marinum_M DRLTRITCGYAATTDSVEVVRRCAELARQYGVPLRVITFAVRGRTMYPPE
MUL_1245|M.ulcerans_Agy99 DRLTRITCGYAATTDSVEVVRRCAELARQYGVPLRVITFAVRVRTMYPPE
MSMEG_1411|M.smegmatis_MC2_155 GGLSRITVAYPGTRDAVDVVERIAALTQRLGVTMRVVTFAVRGRSMYPPL
MAB_3843|M.abscessus_ATCC_1997 GTVSRVTCGYPGTEDAVDVVQQAVRLTQRLHAPLRVVTFAVRGRTMLTAG
Mflv_1999|M.gilvum_PYR-GCK SRIERLTVAYGGHADEGGLVAAGAELARRWSATLRIASFTVRPVTMFSGA
Mvan_1573|M.vanbaalenii_PYR-1 EHFLAVTAAVPSKPGDDNPLPFAIALAGAAGLRMRMLSLVSAEN-----L
. :: . . . : *: :*: ::.
Mb2346c|M.bovis_AF2122/97 VGLHAEASVLEAWAAQARE---LLEKLRINGVVSEDVVLQVVTGNGWAQA
Rv2319c|M.tuberculosis_H37Rv VGLHAEASVLEAWAAQARE---LLEKLRINGVVSEDVVLQVVTGNGWAQA
MMAR_3620|M.marinum_M VGLHAEALVLEAWAEQARG---MLEMLQKDGIVEEDAVLEVITGNGWQHA
MUL_1245|M.ulcerans_Agy99 VGLHAEALVLEAWAEQARG---MLEMLQKDGIVEEDAVLEVITGNGWQHA
MSMEG_1411|M.smegmatis_MC2_155 VGLSKEDLILQEWIEQAQD---SLRRLATDGVIGEDVEVVVASGSAWDEA
MAB_3843|M.abscessus_ATCC_1997 VGPEAEDAVLASWVTQSEE---ALSELRQAGIVTADVELKVVTGDTWDDA
Mflv_1999|M.gilvum_PYR-GCK IETSAEDLVVQQWVRRTQEKIAAQLEAVRSGVDTLDAEVVIGAGATWRDA
Mvan_1573|M.vanbaalenii_PYR-1 AEAGSAKEVRALQVAAAEEN---LAVAARALPDAPDIESLVADGMTLESA
: :. * : * *
Mb2346c|M.bovis_AF2122/97 LDAADWQDGEILALGTSPFGDVARVFLGSWSGKIIRYSPVPVLVLPG---
Rv2319c|M.tuberculosis_H37Rv LDAADWQDGEILALGTSPFGDVARVFLGSWSGKIIRYSPVPVLVLPG---
MMAR_3620|M.marinum_M LDAADWEDGEILAVGTSPRGDIARVFLGSNSGKIIRHSPVPVLVLPG---
MUL_1245|M.ulcerans_Agy99 LDAADWEDGEILAVGTSPRGDIARVFLGSNSGRIIRHSPVPVLVLPG---
MSMEG_1411|M.smegmatis_MC2_155 LDSIEWIEGEVLAIGTSPAGAVRRVFLGERGTKILRYSPLPVLVLPG---
MAB_3843|M.abscessus_ATCC_1997 LDNAEWNDGELLVLGSRPHSAVARVFLGSRATKIVRHSPVPVVVMPG---
Mflv_1999|M.gilvum_PYR-GCK VEAIDWGSGDVLVLGSGAAGQVAQVFLGSAAARILRHSPVPTMIVPRREG
Mvan_1573|M.vanbaalenii_PYR-1 LKKLRWDDGDLLVVGSSRFAAPRRIFLGSTAARILAGVDVPVIVVPKAE-
:. * .*::*.:*: . ::***. . :*: :*.:::*
Mb2346c|M.bovis_AF2122/97 -
Rv2319c|M.tuberculosis_H37Rv -
MMAR_3620|M.marinum_M -
MUL_1245|M.ulcerans_Agy99 -
MSMEG_1411|M.smegmatis_MC2_155 -
MAB_3843|M.abscessus_ATCC_1997 -
Mflv_1999|M.gilvum_PYR-GCK L
Mvan_1573|M.vanbaalenii_PYR-1 -