For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv2319c (-)

annotation: hypothetical protein Rv2319c
coordinates: 2591848 - 2592726
length: 292

TIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTPSLARVDAEYELWSEQLAAASAREAQRY
LRRLADGIEVSYHHRAHRSVSAGLLDVVEELEAEVLVLGSFPSGRRARVLIGSTADRLLHSSPVPVAITP
RRYRCYTDRLTRLSCGYSATSGSVDVVRRCGHLASRYGVPMRVITFAVRGRTMYPPEVGLHAEASVLEAW
AAQARELLEKLRINGVVSEDVVLQVVTGNGWAQALDAADWQDGEILALGTSPFGDVARVFLGSWSGKIIR
YSPVPVLVLPG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv2319c--100% (292)hypothetical protein Rv2319c

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2346c-1e-166100.00% (292) hypothetical protein Mb2346c
M. gilvum PYR-GCKMflv_1999-1e-4433.56% (295) UspA domain-containing protein
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3843-4e-8553.92% (293) hypothetical protein MAB_3843
M. marinum MMMAR_3620-1e-12173.97% (292) hypothetical protein MMAR_3620
M. avium 104MAV_2507-3e-0525.82% (306) universal stress protein family protein
M. smegmatis MC2 155MSMEG_1411-2e-8554.27% (293) universal stress protein family protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1245-1e-11972.95% (292) hypothetical protein MUL_1245
M. vanbaalenii PYR-1Mvan_1573-1e-2128.72% (296) UspA domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv2319c|M.tuberculosis_H37Rv        ---MTIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTPSLA
Mb2346c|M.bovis_AF2122/97           ---MTIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTPSLA
MMAR_3620|M.marinum_M               ---MTVVVGYLAGRVGPSALHLAVRAARTLDTSLTVATILTKPWLTPPLA
MUL_1245|M.ulcerans_Agy99           ---MTVVVGYLAGRVGPSALHLAVRAARTLDTSLTVATILTKPWLTPPLA
MAB_3843|M.abscessus_ATCC_1997      ---MTVVVGYLSGKGGKGALHLAVESARVLETSLTVTTVVPKPWTTLSKA
MSMEG_1411|M.smegmatis_MC2_155      ---MTVVVGYLTGKAGASPLHLAVGAARTLQTSLAVATVVPRPWMTPSPA
Mflv_1999|M.gilvum_PYR-GCK          ---MTIIAGFSASGQGPAPLHLAAQLARCTGERIVAVAIVERQWPQN---
Mvan_1573|M.vanbaalenii_PYR-1       ---MHLTVGYLATPTGDDGVALASALARTFDATVDVVIVVRHELPDG---
MAV_2507|M.avium_104                MAASSKRCGVLVGVDGSPASNFAVCWAARDAAMRNVPLTLVHMVNAATVW
                                            *      *     :*   *        .   : :        

Rv2319c|M.tuberculosis_H37Rv        RVDAEYELWSEQLAAASAREAQRYLRRLADG-IEVSYHHRAHRSVSAGLL
Mb2346c|M.bovis_AF2122/97           RVDAEYELWSEQLAAASAREAQRYLRRLADG-IEVSYHHRAHRSVSAGLL
MMAR_3620|M.marinum_M               KG--DYSEWAEQVAEDSEKEAHRYLRTVATG-IEVSYCHREHRSVSGGLI
MUL_1245|M.ulcerans_Agy99           KG--DYSEWAEQVAEDSEKEAHRYLRTVATG-IEVSYCHREHRSVSGGLI
MAB_3843|M.abscessus_ATCC_1997      KIDAEYAQWAQKLSDDSKSEATAYLEKIGAG-IDVTFHNVAHRSVSGGLL
MSMEG_1411|M.smegmatis_MC2_155      RIDAEYAQYAAQLASTSAEQARQVISELDSE-LEVTFHKFAHRSVSDGLM
Mflv_1999|M.gilvum_PYR-GCK          -ADPLEDEYLNYVGAQAQKSLKEMVDKLPGD-LDVWRMVHQAESVPSGLT
Mvan_1573|M.vanbaalenii_PYR-1       --HPGRAEYQQMLVNLGEQWAARAVAALAADGVTAESSAIVADSFAQALV
MAV_2507|M.avium_104                PQVPMAAEAVAWQEDDGRRVLQEAVKIAEDATRNGRNLAITTELWHAPPA
                                                    .       :                         

Rv2319c|M.tuberculosis_H37Rv        DVVEEL--EAEVLVLGSFPSGRRARVLIGSTADRLLHSSPVPVAITPRRY
Mb2346c|M.bovis_AF2122/97           DVVEEL--EAEVLVLGSFPSGRRARVLIGSTADRLLHSSPVPVAITPRRY
MMAR_3620|M.marinum_M               EVVEEL--DAEMLILGSFPNGRRARVLIGSTADWVLHSSPVPVAISPRQY
MUL_1245|M.ulcerans_Agy99           EVVEEL--DAQMLILGSFPNGRRARVLIGSTADWVLHSSPVPVAISPRQY
MAB_3843|M.abscessus_ATCC_1997      EAVEAS--DADVLVVGSASEGRLGQVVLGSTGDRLLHSSPVPLAISPRGY
MSMEG_1411|M.smegmatis_MC2_155      EAVESL--NAEALVLGSAADGKLGQVVVGSTADRLLHSCPVPLVVSPRGY
Mflv_1999|M.gilvum_PYR-GCK          ELAEEM--NADVVVVGSSSSGLLGRIALGSVTDRLVHTAAVPVAIAPRGY
Mvan_1573|M.vanbaalenii_PYR-1       EFAEEK--SSDLIVVGGARDGFFGRHTIGPVTGALLHSSSIPVALAPRGY
MAV_2507|M.avium_104                PTLAQLSEEAELVVVGSTGRGAIGRLLLGSVSSGLVRRARCPVAVIHDED
                                            .:: :::*.   *  .:  :*.. . ::: .  *:.:     

Rv2319c|M.tuberculosis_H37Rv        R-CYTDRLTRLSCGYSATSGSVDVVRRCGHLASRYGVPMRVITFAVRGRT
Mb2346c|M.bovis_AF2122/97           R-CYTDRLTRLSCGYSATSGSVDVVRRCGHLASRYGVPMRVITFAVRGRT
MMAR_3620|M.marinum_M               H-SRTDRLTRITCGYAATTDSVEVVRRCAELARQYGVPLRVITFAVRGRT
MUL_1245|M.ulcerans_Agy99           H-SRTDRLTRITCGYAATTDSVEVVRRCAELARQYGVPLRVITFAVRVRT
MAB_3843|M.abscessus_ATCC_1997      RGSRAGTVSRVTCGYPGTEDAVDVVQQAVRLTQRLHAPLRVVTFAVRGRT
MSMEG_1411|M.smegmatis_MC2_155      RRPRSGGLSRITVAYPGTRDAVDVVERIAALTQRLGVTMRVVTFAVRGRS
Mflv_1999|M.gilvum_PYR-GCK          P-LQDSRIERLTVAYGGHADEGGLVAAGAELARRWSATLRIASFTVRPVT
Mvan_1573|M.vanbaalenii_PYR-1       AEDPDEHFLAVTAAVPSKPGDDNPLPFAIALAGAAGLRMRMLSLVSAEN-
MAV_2507|M.avium_104                PMMPYPQRAPVLVGIDGSPASELATAIAFDEALRRGVDLNAVHAWSDTQV
                                              :  .  .              :      :.          

Rv2319c|M.tuberculosis_H37Rv        MYPPEVGLHAEASVLEAWAAQARE---LLEKLRINGVVSEDVVLQVVTGN
Mb2346c|M.bovis_AF2122/97           MYPPEVGLHAEASVLEAWAAQARE---LLEKLRINGVVSEDVVLQVVTGN
MMAR_3620|M.marinum_M               MYPPEVGLHAEALVLEAWAEQARG---MLEMLQKDGIVEEDAVLEVITGN
MUL_1245|M.ulcerans_Agy99           MYPPEVGLHAEALVLEAWAEQARG---MLEMLQKDGIVEEDAVLEVITGN
MAB_3843|M.abscessus_ATCC_1997      MLTAGVGPEAEDAVLASWVTQSEE---ALSELRQAGIVTADVELKVVTGD
MSMEG_1411|M.smegmatis_MC2_155      MYPPLVGLSKEDLILQEWIEQAQD---SLRRLATDGVIGEDVEVVVASGS
Mflv_1999|M.gilvum_PYR-GCK          MFSGAIETSAEDLVVQQWVRRTQEKIAAQLEAVRSGVDTLDAEVVIGAGA
Mvan_1573|M.vanbaalenii_PYR-1       ----LAEAGSAKEVRALQVAAAEEN---LAVAARALPDAPDIESLVADGM
MAV_2507|M.avium_104                FGLPGMDWPAVRSQAERSLAERLAG-------WQERYPDVTVHRMVVCDR
                                                                                 :  . 

Rv2319c|M.tuberculosis_H37Rv        GWAQALDAADWQDGEILALGTSPFGDVARVFLGSWSGKIIRYSPVPVLVL
Mb2346c|M.bovis_AF2122/97           GWAQALDAADWQDGEILALGTSPFGDVARVFLGSWSGKIIRYSPVPVLVL
MMAR_3620|M.marinum_M               GWQHALDAADWEDGEILAVGTSPRGDIARVFLGSNSGKIIRHSPVPVLVL
MUL_1245|M.ulcerans_Agy99           GWQHALDAADWEDGEILAVGTSPRGDIARVFLGSNSGRIIRHSPVPVLVL
MAB_3843|M.abscessus_ATCC_1997      TWDDALDNAEWNDGELLVLGSRPHSAVARVFLGSRATKIVRHSPVPVVVM
MSMEG_1411|M.smegmatis_MC2_155      AWDEALDSIEWIEGEVLAIGTSPAGAVRRVFLGERGTKILRYSPLPVLVL
Mflv_1999|M.gilvum_PYR-GCK          TWRDAVEAIDWGSGDVLVLGSGAAGQVAQVFLGSAAARILRHSPVPTMIV
Mvan_1573|M.vanbaalenii_PYR-1       TLESALKKLRWDDGDLLVVGSSRFAAPRRIFLGSTAARILAGVDVPVIVV
MAV_2507|M.avium_104                PARQLIEQSES--AQLTVVGSHGRGGLAGTLLGSVSNAVVHSVRMPVIVA
                                         :.      .:: .:*:   .     :**. .  ::    :*.:: 

Rv2319c|M.tuberculosis_H37Rv        PG----
Mb2346c|M.bovis_AF2122/97           PG----
MMAR_3620|M.marinum_M               PG----
MUL_1245|M.ulcerans_Agy99           PG----
MAB_3843|M.abscessus_ATCC_1997      PG----
MSMEG_1411|M.smegmatis_MC2_155      PG----
Mflv_1999|M.gilvum_PYR-GCK          PRREGL
Mvan_1573|M.vanbaalenii_PYR-1       PKAE--
MAV_2507|M.avium_104                RPS---