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HLTVGYLATPTGDDGVALASALARTFDATVDVVIVVRHELPDGHPGRAEYQQMLVNLGEQWAARAVAALA ADGVTAESSAIVADSFAQALVEFAEEKSSDLIVVGGARDGFFGRHTIGPVTGALLHSSSIPVALAPRGYA EDPDEHFLAVTAAVPSKPGDDNPLPFAIALAGAAGLRMRMLSLVSAENLAEAGSAKEVRALQVAAAEENL AVAARALPDAPDIESLVADGMTLESALKKLRWDDGDLLVVGSSRFAAPRRIFLGSTAARILAGVDVPVIV VPKAE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1573 | - | - | 100% (286) | UspA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1386 | - | 7e-07 | 27.09% (203) | UspA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1378 | - | 7e-07 | 26.64% (229) | UspA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2346c | - | 9e-22 | 28.72% (296) | hypothetical protein Mb2346c |
| M. gilvum PYR-GCK | Mflv_4854 | - | 1e-134 | 85.21% (284) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv2319c | - | 9e-22 | 28.72% (296) | hypothetical protein Rv2319c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4205 | - | 6e-43 | 35.09% (285) | hypothetical protein MAB_4205 |
| M. marinum M | MMAR_3620 | - | 2e-18 | 25.51% (294) | hypothetical protein MMAR_3620 |
| M. avium 104 | MAV_2494 | - | 1e-06 | 25.69% (218) | universal stress protein family protein |
| M. smegmatis MC2 155 | MSMEG_1624 | - | 2e-47 | 37.50% (288) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 2e-06 | 25.21% (242) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_1245 | - | 6e-19 | 26.19% (294) | hypothetical protein MUL_1245 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1573|M.vanbaalenii_PYR-1 ------MHLTVGYLATPTGDDGVALASALARTFDATVDVVIVVRHELPDG
Mflv_4854|M.gilvum_PYR-GCK ------MHLTVGYLATPTGDDGIALASALAKTFDATVDVVIVVREELPDG
MAB_4205|M.abscessus_ATCC_1997 -MNTAATRIAVAYLATPGGDDALAVGAQIARSLGAHLDLCMVLPLDRPIL
MSMEG_1624|M.smegmatis_MC2_155 ------MKLVVGYLATPGGADALALGIRFARTLGAELEICIVLPPDTRAP
Mb2346c|M.bovis_AF2122/97 ------MTIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTP
Rv2319c|M.tuberculosis_H37Rv ------MTIVVGYLAGKVGPSALHLAVRVARMHKTSLTVATIVRRHWPTP
MMAR_3620|M.marinum_M ------MTVVVGYLAGRVGPSALHLAVRAARTLDTSLTVATILTKPWLTP
MUL_1245|M.ulcerans_Agy99 ------MTVVVGYLAGRVGPSALHLAVRAARTLDTSLTVATILTKPWLTP
MAV_2494|M.avium_104 -----------------------MRTIRTAAAFSSGLYLRVVGFPGDCSF
TH_2494|M.thermoresistible__bu VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRN-LQLTLVHVMTATSI
: : : :
Mvan_1573|M.vanbaalenii_PYR-1 H-----------------PGRAE-----YQQMLVNLGEQWAARAVAALAA
Mflv_4854|M.gilvum_PYR-GCK H-----------------PGRLE-----YQQMLIRRGEEWVAKAVEALAV
MAB_4205|M.abscessus_ATCC_1997 AP----------------LPQQE-----RQDILSQNAAHWLNHAEATVPD
MSMEG_1624|M.smegmatis_MC2_155 G-----------------MPKGG-----YEEVLAGQAQEWLDDALKRVPD
Mb2346c|M.bovis_AF2122/97 S-----------------LARVDAEYELWSEQLAAASAREAQRYLRRLAD
Rv2319c|M.tuberculosis_H37Rv S-----------------LARVDAEYELWSEQLAAASAREAQRYLRRLAD
MMAR_3620|M.marinum_M P-----------------LAKG--DYSEWAEQVAEDSEKEAHRYLRTVAT
MUL_1245|M.ulcerans_Agy99 P-----------------LAKG--DYSEWAEQVAEDSEKEAHRYLRTVAT
MAV_2494|M.avium_104 G-------------------------------IAPSSFPRSGAS------
TH_2494|M.thermoresistible__bu GAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPAG
: .
Mvan_1573|M.vanbaalenii_PYR-1 DGVTAESSAIVADSFAQALVEFAEEKSSDLIVVGGARDGFFGRHTIGPVT
Mflv_4854|M.gilvum_PYR-GCK DGVSAGSAVIVGESFAQTLVEFAESKSSDLIVVGGARDGFFGRHTIGPVT
MAB_4205|M.abscessus_ATCC_1997 D-LSVTTHISFHESIAEGLIAQSEALGAAAIVVGGSGGGLVGSLSLGSVV
MSMEG_1624|M.smegmatis_MC2_155 D-VVAHGHVTFAESFTDGLIGLAQKHDAVAIVVGGSGGGLVGSFSLGSVV
Mb2346c|M.bovis_AF2122/97 G-IEVSYHHRAHRSVSAGLLDVVEELEAEVLVLGSFPSGRRARVLIGSTA
Rv2319c|M.tuberculosis_H37Rv G-IEVSYHHRAHRSVSAGLLDVVEELEAEVLVLGSFPSGRRARVLIGSTA
MMAR_3620|M.marinum_M G-IEVSYCHREHRSVSGGLIEVVEELDAEMLILGSFPNGRRARVLIGSTA
MUL_1245|M.ulcerans_Agy99 G-IEVSYCHREHRSVSGGLIEVVEELDAQMLILGSFPNGRRARVLIGSTA
MAV_2494|M.avium_104 ----RISRAIHYSAPVPALLELSG--AVRMLVLGSAGHGLLARGLLGSVS
TH_2494|M.thermoresistible__bu DDAVRVVTGVVRAAPVPTLVDASK--QAKLVAVGSRGQGPLRRVLLGSVS
: *: : :*. * :*..
Mvan_1573|M.vanbaalenii_PYR-1 GALLHSSSIPVALAPRGYAEDPDEHFLAVTAAVPSKPGDDNPLPFAIALA
Mflv_4854|M.gilvum_PYR-GCK GALLHISPIPVALAPRGYAEDPDDKIEALTAAVPTRPGDDNPLPFTIRLA
MAB_4205|M.abscessus_ATCC_1997 NELVHSSPIPLVISPRGARYQKNLRIREVTCAMGTRPGARVLLDTALRIC
MSMEG_1624|M.smegmatis_MC2_155 SELLHSSPLPVAVAPRGTRESAIKKVREVTCAIGQRQGADRLLATAVAAS
Mb2346c|M.bovis_AF2122/97 DRLLHSSPVPVAITPRRYR-CYTDRLTRLSCGYSATSGSVDVVRRCGHLA
Rv2319c|M.tuberculosis_H37Rv DRLLHSSPVPVAITPRRYR-CYTDRLTRLSCGYSATSGSVDVVRRCGHLA
MMAR_3620|M.marinum_M DWVLHSSPVPVAISPRQYH-SRTDRLTRITCGYAATTDSVEVVRRCAELA
MUL_1245|M.ulcerans_Agy99 DWVLHSSPVPVAISPRQYH-SRTDRLTRITCGYAATTDSVEVVRRCAELA
MAV_2494|M.avium_104 SAVVRHANCPVAVVRD--EELPDPHSAPVLLGTDGSPASELATEIAFDEA
TH_2494|M.thermoresistible__bu SGLVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEEA
. ::: : *:.: : . .
Mvan_1573|M.vanbaalenii_PYR-1 GAAGLRMRMLSLVSAEN---LAE--AGSAKEVRALQVAAAEENLAVAARA
Mflv_4854|M.gilvum_PYR-GCK ALAQLRIRMLSLVSAEN---LAE--AGSAREVRALQRAAAEENLAVAARE
MAB_4205|M.abscessus_ATCC_1997 KRAETPLRLVSLVSIDP---IPG--GDDDQSARERATIHAQQSLETAKLV
MSMEG_1624|M.smegmatis_MC2_155 KAAGTPLRLVSLVALDP---AFGHLRSDDDAVRRRAHEHAQKTLDAAKAE
Mb2346c|M.bovis_AF2122/97 SRYGVPMRVITFAVRGRTMYPPEVGLHAEASVLEAWAAQARELLEKLRIN
Rv2319c|M.tuberculosis_H37Rv SRYGVPMRVITFAVRGRTMYPPEVGLHAEASVLEAWAAQARELLEKLRIN
MMAR_3620|M.marinum_M RQYGVPLRVITFAVRGRTMYPPEVGLHAEALVLEAWAEQARGMLEMLQKD
MUL_1245|M.ulcerans_Agy99 RQYGVPLRVITFAVRVRTMYPPEVGLHAEALVLEAWAEQARGMLEMLQKD
MAV_2494|M.avium_104 SRRGVDLVAIHAWSDTA---VTEVFEIDWPIVEAEAERHLAESLAGWQER
TH_2494|M.thermoresistible__bu SFRGVDLIALHAWSDAD---IADIPTLELSAVQQSAERVLSERLAGFRER
: : . *
Mvan_1573|M.vanbaalenii_PYR-1 LPDAPDIESLVADGMTLESALKKLRWDDGDLLVVGSSRFAAPRRIFLGST
Mflv_4854|M.gilvum_PYR-GCK LPDAPDIESLVADGMTLESALKKLKWDDGDLLVVGSSRFAAPKRIFLGST
MAB_4205|M.abscessus_ATCC_1997 LPPDFPVTSTVAEGPTVEAAVNKLDWHEGDIIMVGSSRLAQPRRLFLGST
MSMEG_1624|M.smegmatis_MC2_155 LPEGFPVTSTIVSGTSVENAVSQLDWHDGDVIMVGSSRLSAPKRIFLGNT
Mb2346c|M.bovis_AF2122/97 GVVSEDVVLQVVTGNGWAQALDAADWQDGEILALGTSPFGDVARVFLGSW
Rv2319c|M.tuberculosis_H37Rv GVVSEDVVLQVVTGNGWAQALDAADWQDGEILALGTSPFGDVARVFLGSW
MMAR_3620|M.marinum_M GIVEEDAVLEVITGNGWQHALDAADWEDGEILAVGTSPRGDIARVFLGSN
MUL_1245|M.ulcerans_Agy99 GIVEEDAVLEVITGNGWQHALDAADWEDGEILAVGTSPRGDIARVFLGSN
MAV_2494|M.avium_104 -YPDVTVHRLVARDRAAQHIISSS--ETAQLVVVGSHGRGGLARLLLGSV
TH_2494|M.thermoresistible__bu -YPDVSVHRRIVGSEPARHLVEAS--EDAQLVVVGSRGRGGFTGMLLGSV
: . :. . .::: :*: . ::**.
Mvan_1573|M.vanbaalenii_PYR-1 AARILAGVDVPVIVVPK---AE-----
Mflv_4854|M.gilvum_PYR-GCK ASRILAGVDVPVIVVPR---EG-----
MAB_4205|M.abscessus_ATCC_1997 AAKMLRVLQVPMVVIPK---EEGGDSD
MSMEG_1624|M.smegmatis_MC2_155 AAKMLRVLDVPMVVVPRDDLEDGEDRS
Mb2346c|M.bovis_AF2122/97 SGKIIRYSPVPVLVLPG----------
Rv2319c|M.tuberculosis_H37Rv SGKIIRYSPVPVLVLPG----------
MMAR_3620|M.marinum_M SGKIIRHSPVPVLVLPG----------
MUL_1245|M.ulcerans_Agy99 SGRIIRHSPVPVLVLPG----------
MAV_2494|M.avium_104 SNAVLHSVRVPVIVARPPA--------
TH_2494|M.thermoresistible__bu SRAVVNAVTTPVIVAR-----------
: :: .*::*