For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_5304 (-)

annotation: two-component sensor kinase
coordinates: 5394189 - 5395772
length: 527

VSGWRPELLARSWPRSLAGQAIALQVIVVAVVVLAGSVLAVYDARRDGEENARDQVVGIATALADSPSTA
EAIESGHATEILQPVTEAVRTGTGIAFITIMSPDGIRFTHTDPSQIGGHYLGTIDPALRGETYTEIYTGT
LGPSVRAIVPVRDADENIVGLVSAGITTQTLAQRWRGQLVTIAAVTACALVLSLIGVWAIRRRLLRQTHG
LRPDELRVMYDHHDAILHSVSEGLIVLDGGGVALVNDEARRLLGLPPGPVRLDDLPGFLRSHDPGARDEL
HVTDERVLVVNHARVADTGSEVVTIRDRTELQGALGELSSLQVLTDSLRAQAHESANKLHTVITMVEMGR
PQDAVRFATSELELSQRLVDRLSEAVSEPALVALLLGKTAQADERGIALTVTEDTQLSDETVLSGPELVT
VLGNLIDNAMDACDRDDPWIEVTVTSDDDQLLITVADSGPGMDPDTFEKATQRGYSTKADTSGHGLGLAL
VAQVVNKHGGTLHADVTYGSVVTVTVPIPERVGGGHA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_5304--100% (527)two-component sensor kinase
M. smegmatis MC2 155MSMEG_4211-2e-5630.49% (528) two component system histidine kinase
M. smegmatis MC2 155MSMEG_5870-1e-0936.19% (105) sensor histidine kinase PhoR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0781phoR2e-0827.23% (224) two component system response sensor kinase membrane
M. gilvum PYR-GCKMflv_3003-1e-5533.94% (495) signal transduction histidine kinase regulating citrate/malate
M. tuberculosis H37RvRv0758phoR2e-0827.23% (224) two component system response sensor kinase membrane
M. leprae Br4923MLBr_00774mtrB1e-0628.57% (154) putative two-component system sensor kinase
M. abscessus ATCC 19977MAB_3251c-1e-0924.68% (389) sensor protein KdpD
M. marinum MMMAR_4941phoR7e-0832.59% (135) two-component system response phosphate sensor kinase, PhoR
M. avium 104MAV_3405-4e-1127.47% (273) hypothetical protein MAV_3405
M. thermoresistible (build 8)TH_2452-5e-1029.87% (231) PUTATIVE putative sensor histidine kinase PhoR
M. ulcerans Agy99MUL_0464phoR3e-0832.59% (135) two component system response phosphate sensor kinase, PhoR
M. vanbaalenii PYR-1Mvan_4697-0.073.45% (516) signal transduction histidine kinase regulating citrate/malate

CLUSTAL 2.0.9 multiple sequence alignment


Mb0781|M.bovis_AF2122/97            --------------------------------------------------
Rv0758|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4941|M.marinum_M               --------------------------------------------------
MUL_0464|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_5304|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4697|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_3405|M.avium_104                --------------------------------------------------
Mflv_3003|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_00774|M.leprae_Br4923          --------------------------------------------------
TH_2452|M.thermoresistible__bu      --------------------------------------------------
MAB_3251c|M.abscessus_ATCC_199      MPDGLRARGTLRIYLGAAPGVGKTFAMLNEAHRRAGRGTDVVAAVVETHG
                                                                                      

Mb0781|M.bovis_AF2122/97            --------------------------------------------------
Rv0758|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4941|M.marinum_M               --------------------------------------------------
MUL_0464|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_5304|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4697|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_3405|M.avium_104                --------------------------------------------------
Mflv_3003|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_00774|M.leprae_Br4923          --------------------------------------------------
TH_2452|M.thermoresistible__bu      --------------------------------------------------
MAB_3251c|M.abscessus_ATCC_199      RSKTAELLDGLELIPPKEMVHRGTAMYELDVDAVLERRPALVLIDEMAHT
                                                                                      

Mb0781|M.bovis_AF2122/97            --------------------------------------------------
Rv0758|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4941|M.marinum_M               --------------------------------------------------
MUL_0464|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_5304|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4697|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_3405|M.avium_104                --------------------------------------------------
Mflv_3003|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_00774|M.leprae_Br4923          --------------------------------------------------
TH_2452|M.thermoresistible__bu      --------------------------------------------------
MAB_3251c|M.abscessus_ATCC_199      NVPGSRNPKRWQDIDEILDAGIDVLTTINVQHLESLNDVVEQITGIVQRE
                                                                                      

Mb0781|M.bovis_AF2122/97            --------------------------------------------------
Rv0758|M.tuberculosis_H37Rv         --------------------------------------------------
MMAR_4941|M.marinum_M               --------------------------------------------------
MUL_0464|M.ulcerans_Agy99           --------------------------------------------------
MSMEG_5304|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_4697|M.vanbaalenii_PYR-1       --------------------------------------------------
MAV_3405|M.avium_104                --------------------------------------------------
Mflv_3003|M.gilvum_PYR-GCK          --------------------------------------------------
MLBr_00774|M.leprae_Br4923          --------------------------------------------------
TH_2452|M.thermoresistible__bu      --------------------------------------------------
MAB_3251c|M.abscessus_ATCC_199      TVPDAVVRRAEQVELVDITPEALRRRMVHGNVYAPEKVGSALSNYFRTGN
                                                                                      

Mb0781|M.bovis_AF2122/97            -----------------------------------------------MAR
Rv0758|M.tuberculosis_H37Rv         -----------------------------------------------MAR
MMAR_4941|M.marinum_M               -----------------------------------------------MAE
MUL_0464|M.ulcerans_Agy99           -----------------------------------------------MAE
MSMEG_5304|M.smegmatis_MC2_155      ----------------------------MSGWRPELLARSWPRSLAGQAI
Mvan_4697|M.vanbaalenii_PYR-1       ----------------------------MRRIRSPSRS-PWPRSLAGQAV
MAV_3405|M.avium_104                -----------------------------------------MFSGGPRAC
Mflv_3003|M.gilvum_PYR-GCK          -----------------------------------------MAQSEGEFR
MLBr_00774|M.leprae_Br4923          --------------------MIFSSRRRIRGRWGRSGPMMRGMGALTRVV
TH_2452|M.thermoresistible__bu      ------------------------------------MTSEPPSPSGRPRW
MAB_3251c|M.abscessus_ATCC_199      LTALRELALLWLADQVDAALAKYRSDNRITKTWEARERVVVAVTGGPESE
                                                                                      

Mb0781|M.bovis_AF2122/97            HLRGRLPLRVRLVAATLILVATG---------------------------
Rv0758|M.tuberculosis_H37Rv         HLRGRLPLRVRLVAATLILVATG---------------------------
MMAR_4941|M.marinum_M               RLPRAVPLRVGLVAATLALVLCG---------------------------
MUL_0464|M.ulcerans_Agy99           RLPRAVQLRVGLVAATLALVLCG---------------------------
MSMEG_5304|M.smegmatis_MC2_155      ALQVIVVAVVVLAGSVLAVYDARRDGEEN---------------------
Mvan_4697|M.vanbaalenii_PYR-1       ALQILVITLIVLAGSALAVLDARRDGDAA---------------------
MAV_3405|M.avium_104                RIEGVHLGISARSAAVAAIVVFC---------------------------
Mflv_3003|M.gilvum_PYR-GCK          DVRGQRMIAVAENMASTPIVRER---------------------------
MLBr_00774|M.leprae_Br4923          GVVWRRSLQLRVVALTFGLSLAVILALGF---------------------
TH_2452|M.thermoresistible__bu      RRLLPSAARTRIIGWVLLLVMVA---------------------------
MAB_3251c|M.abscessus_ATCC_199      TLVRRASRIAAKSSAELLVVHVVRGDGLVGASTAVMTRVRRLANDIGASV
                                                      :                               

Mb0781|M.bovis_AF2122/97            --------------LVASGIAVTSMLQHRLTSRIDRVLLE----------
Rv0758|M.tuberculosis_H37Rv         --------------LVASGIAVTSMLQHRLTSRIDRVLLE----------
MMAR_4941|M.marinum_M               --------------LLASGVAVTSILRHSLVSRIDSTLLE----------
MUL_0464|M.ulcerans_Agy99           --------------LLASGVAVTSILRHSLVSRIDSTLLE----------
MSMEG_5304|M.smegmatis_MC2_155      ----ARDQVVGIATALADSPSTAEAIESGHATEILQPVTE----------
Mvan_4697|M.vanbaalenii_PYR-1       ----AEAQVLGIATSLADSPSTAQAIESGRATEILQPVTE----------
MAV_3405|M.avium_104                -------------ALTVAGAGLDAILYRSLLSGVDYAAAE----------
Mflv_3003|M.gilvum_PYR-GCK          ---------------------TEQTRADPFLARTLAPEVD----------
MLBr_00774|M.leprae_Br4923          ----VLTSQLTSRVLDVKVRVAIEQIERARTTVTGIVNGE----------
TH_2452|M.thermoresistible__bu      --------------LGVVTLTTWRLMVSSIDARMDEALHI----------
MAB_3251c|M.abscessus_ATCC_199      QAVTGDDVPQTLLDFARGVNATQLVLGTSRRSRWARILDEGVAAAVIRDS
                                                                   :                  

Mb0781|M.bovis_AF2122/97            ---EAQIWAQITLPLAPDPYPIHNPDRPPSRF---YVRVISP--------
Rv0758|M.tuberculosis_H37Rv         ---EAQIWAQITLPLAPDPYPGHNPDRPPSRF---YVRVISP--------
MMAR_4941|M.marinum_M               ---ASRTWAQASWRHSMPSVEGPDPARPPSKF---YVRSISP--------
MUL_0464|M.ulcerans_Agy99           ---ASRTWAQASWRHSMPSVEGPDPARPPSKF---YVRSISP--------
MSMEG_5304|M.smegmatis_MC2_155      ---AVRTGTGIAFITIMSPDGIRFTHTDPSQIGGHYLGTIDPAL------
Mvan_4697|M.vanbaalenii_PYR-1       ---QVRTHTDIAFITIMAPDRTRFTHTDPSQIGGDYLGTIEPAL------
MAV_3405|M.avium_104                ---RVRDIAKALQSDSREELDNALLTTDQRVV---ATQLIGP--------
Mflv_3003|M.gilvum_PYR-GCK          ---RAVALSGASLAEILGPDGTVRASSDPSRVGARVDLGATRAD------
MLBr_00774|M.leprae_Br4923          ---ETRSLDSSLQLARNTLTSKTDPTSGAGLVGAFDAVLIVPGD------
TH_2452|M.thermoresistible__bu      ---EVDEFEELTASGLNPRTGAPFTGVAEVIREAIAYNLARPNEKFLGYV
MAB_3251c|M.abscessus_ATCC_199      GAIDVHMVTHGHTSGRLRSWSVPQDGRKRLIINWLAAILVPPATALFIHF
                                                                                      

Mb0781|M.bovis_AF2122/97            DGQSYTALNDNTAIP-AVPANNDVGRHPTTLPSIGGS-------------
Rv0758|M.tuberculosis_H37Rv         DGQSYTALNDNTAIP-AVPANNDVGRHPTTLPSIGGS-------------
MMAR_4941|M.marinum_M               DGRAMTAINDRNAEP-ALPADNDVGSDPTTLPSVNGS-------------
MUL_0464|M.ulcerans_Agy99           DGRAMTAINDRNAEP-ALPADNDVGSDPTTLPSVNGS-------------
MSMEG_5304|M.smegmatis_MC2_155      RGETYTEIYTGTLGP-SVRAIVPVRDADENIVGLVSAGITTQTL------
Mvan_4697|M.vanbaalenii_PYR-1       RGETFTEVYTGTLGP-SIRAVAPVRDSSGRIVGLVAAGILQQSL------
MAV_3405|M.avium_104                DGSVVKRSGSAPATP-LVPTADFDFTLRRGLPDDAVSG----DD------
Mflv_3003|M.gilvum_PYR-GCK          EGRAWFGDTDIDGTH-SLVGQVPILSTDGEVLAIASVSEAYPSV------
MLBr_00774|M.leprae_Br4923          GPRTATTAGPVDQVPNSLRGFIKAGQAAYQYATVHTEG--FSGP------
TH_2452|M.thermoresistible__bu      DGEYHTQSRQEPGFPEVLAGDDAFTERVATVTEPVEGSYDHPEVGEVR--
MAB_3251c|M.abscessus_ATCC_199      FDTAFGVGSKSALFLIAVLGVSLLGGVSTALVSAVISGLLLNFLFVAPRY
                                                     :                                

Mb0781|M.bovis_AF2122/97            KTLWRAVSVRASDGYLTTVAIDLADVRSTVRSLVLLQVGIGSAVLVVLGV
Rv0758|M.tuberculosis_H37Rv         KTLWRAVSVRASDGYLTTVAIDLADVRSTVRSLVLLQVGIGSAVLVVPGV
MMAR_4941|M.marinum_M               NIEWRAVSVHGPQGGLTTVAIDLSDVQHTVRSLVWLQIGIGAGVLVVVGL
MUL_0464|M.ulcerans_Agy99           NIEWRAVSVHGPQGGLTTVAIDLSDVQHTVRSLVWLQIGIGAGVLVVVGL
MSMEG_5304|M.smegmatis_MC2_155      AQRWRGQLVTIAAVTACALVLSLIGVWAIRRRLLRQTHGLRPDELRVMYD
Mvan_4697|M.vanbaalenii_PYR-1       ADRWQAQWPAIAAVGLGALAVSLLGGWGIRRRLMRQTRGLRPEELRVMYD
MAV_3405|M.avium_104                MRVSGQKVATRSGVYTVLVGGGSEAVEATARTLAILLATTAPVIVAVAAG
Mflv_3003|M.gilvum_PYR-GCK          WGLLSGAGESLLVYLGLGAALGLLASWLLSRRIKRQTGGLEVAEIASLAD
MLBr_00774|M.leprae_Br4923          ALIIGTPTSSQVTNLELYLIFPLKNEQATVTLVRGTMATGGMVLLVLLSG
TH_2452|M.thermoresistible__bu      YLAIPVTMAGDPAQGVIVAAYLGDAERAAADDAARLMLLVGAATLFGAIG
MAB_3251c|M.abscessus_ATCC_199      SFTIGETDNALTILMMMVTAVAVAALVDAAATRARQARRASREAELLALF
                                                                                      

Mb0781|M.bovis_AF2122/97            AGYAVVRRSLRPLAEFEQTA-----------AAIGAGQLDRRVPQWHPRT
Rv0758|M.tuberculosis_H37Rv         AGYAVVRRSLRPLAEFEQTA-----------AAIGAGQLDRRVPQWHPRT
MMAR_4941|M.marinum_M               AGFAVVQRSLRPLSEVEQTA-----------AAIASGQLDRRVPERDPRT
MUL_0464|M.ulcerans_Agy99           AGFAVVQRSLRPLSEVEQTA-----------AAIASGQLDRRVPERDPRT
MSMEG_5304|M.smegmatis_MC2_155      HHDAILHSVSEGLIVLDGGG-----------VALVNDEARRLLGLPPGPV
Mvan_4697|M.vanbaalenii_PYR-1       HHDAILHSVSEGLIVLDRSG-----------VAVVNDEARRLLSLPAGEV
MAV_3405|M.avium_104                ATYWLVRRSLKSVDAIRARV-----------ADISASDLAERVPVPDGRD
Mflv_3003|M.gilvum_PYR-GCK          HREALLHSIREGVIAVNGSGE----------ITLLNDGAQELLDVTGPAV
MLBr_00774|M.leprae_Br4923          IALLVSRQVVVPVRSASRIA-----------ERFAEGHLSERMPVRGEDD
TH_2452|M.thermoresistible__bu      AAWLVAGRILRPLRDVADTA-----------RTITDTDLSRRIPSRGEGD
MAB_3251c|M.abscessus_ATCC_199      AGGVLVNSDLSALLERVRTTYNQTAVSLLCAEGPAVASVGEDPPTRESEA
                                        :       :                           .         

Mb0781|M.bovis_AF2122/97            ---------EVGRLSLALNG----MLAQIQRAVASAESSAEKARDS----
Rv0758|M.tuberculosis_H37Rv         ---------EVGRLSLALNG----MLAQIQRAVASAESSAEKARDS----
MMAR_4941|M.marinum_M               ---------EVGQLSLAMNG----MLSQIQVALAASEDSAEKARSS----
MUL_0464|M.ulcerans_Agy99           ---------EVGQLSLAMNG----MLSQIQVALAASEDSAEKARSS----
MSMEG_5304|M.smegmatis_MC2_155      ---------RLDDLPGFLRS----HDPGARDELHVTDERVLVVNHARVAD
Mvan_4697|M.vanbaalenii_PYR-1       ---------ARSDLPEFLRT----YNPGARDEVHVTDDRVLVVNRSPVRD
MAV_3405|M.avium_104                ---------EIAALAVTMNE----MLSRLEAGHRAQQR------------
Mflv_3003|M.gilvum_PYR-GCK          GRPVDSVGIDPAVVSLLTPG----QESESAMDTVIATRTRVLALSRRPAT
MLBr_00774|M.leprae_Br4923          ----------MARLAVSFND----MAESLSRQITQLEEFG----------
TH_2452|M.thermoresistible__bu      ---------EMDSLVRTING----MLDRIEAGVSAQRR------------
MAB_3251c|M.abscessus_ATCC_199      DSVFR---VDDGAYALALNGPPVPSSDARVLQVVAGTAVGLVRSARLAEE
                                                                                      

Mb0781|M.bovis_AF2122/97            ----------EDRMRQFITDASHELRTPLTTIR-GFAELYRQGAARD-VG
Rv0758|M.tuberculosis_H37Rv         ----------EDRMRQFITDASHELRTPLTTIR-GFAELYRQGAARD-VG
MMAR_4941|M.marinum_M               ----------EERMRRFITDASHELRTPLTTIR-GFAELYRQGAARD-VA
MUL_0464|M.ulcerans_Agy99           ----------EERMRRFITDASHELRTPLTTIR-GFAELYRQGAARD-VA
MSMEG_5304|M.smegmatis_MC2_155      T----GSEVVTIRDRTELQGALGELSS-LQVLT-DSLRAQAHESANK-LH
Mvan_4697|M.vanbaalenii_PYR-1       GSDAGGSEVVTIRDRTELQGALGELNS-LKVLT-DSLRAQAHEAANK-LH
MAV_3405|M.avium_104                ----------------FVGDASHELRSPLTTIISGLEVAEAHPELLD-AE
Mflv_3003|M.gilvum_PYR-GCK          SQGRRIGTVTTMRDSTELAALQGQLSSHKSVTD--TLRAQAHEFANQ-LH
MLBr_00774|M.leprae_Br4923          -----------NLQRRFTSDVSHELRTPLTTVRMAADLIYDHSSDLD-PT
TH_2452|M.thermoresistible__bu      ----------------FIDDAGHELRTPITIVR-GHLEVLDPDDPDD-VR
MAB_3251c|M.abscessus_ATCC_199      ASQASALAEADRLRRALLSAVSHDLRTPLAAVKAAVSSLRSPDIEFSPED
                                                           :* :                   .   

Mb0781|M.bovis_AF2122/97            MLLSRIESEASR--MGLLVDDLLLLARLDA-HRPLELCRVDLLALASDAA
Rv0758|M.tuberculosis_H37Rv         MLLSRIESEASR--MGLLVDDLLLLARLDA-HRPLELCRVDLLALASDAA
MMAR_4941|M.marinum_M               MLLSRIESEASR--MGLLVDDLLTLARLDV-QRPLERNRVDLLVLAADAV
MUL_0464|M.ulcerans_Agy99           MLLSRIESEASR--MGLLVDDLLTLARLDV-QRPLERNRVDLLVLAADAV
MSMEG_5304|M.smegmatis_MC2_155      TVITMVEMGRPQDAVRFATSELELSQRLVD-RLSEAVSEPALVALLLGKT
Mvan_4697|M.vanbaalenii_PYR-1       TVVTMVEMGRAEEAITFATAGLELSQQLVD-RLSSAVGEPALVALLLGKT
MAV_3405|M.avium_104                LAVNTLLPEAHR--MRALIDDLLLLARADE-RNLLRRK----ELVALDDL
Mflv_3003|M.gilvum_PYR-GCK          TISGLVQLGEFDAVRDLVGTLTRRRAEISD-AVTQRISDPAVAALLIAKT
MLBr_00774|M.leprae_Br4923          LRRSTELMVSELDRFETLLNDLLEISRHDAGVAELSVEAVDLRVMVNNAL
TH_2452|M.thermoresistible__bu      STVALVDDELVR--MNRMVTDLLLLARSEQ-PTFLTPEPTDIGALTRAIF
MAB_3251c|M.abscessus_ATCC_199      TAELLATVEESADQLTALVGNLLDSSRLAA-----GVVKPRAVPVYVDEI
                                                              .                 :     

Mb0781|M.bovis_AF2122/97            HDARAMDPKRRITLEVLDGPGTPEVLGDESRLRQVLRNLVANAIQHT-PE
Rv0758|M.tuberculosis_H37Rv         HDARAMDPKRRITLEVLDGPGTPEVLGDESRLRQVLRNLVANAIQHT-PE
MMAR_4941|M.marinum_M               HDARAIDRKRAITVEVLEGPGTPEVLGDEPRLRQVLSNLVGNALQHT-PD
MUL_0464|M.ulcerans_Agy99           HDARAIDRKRAITVEVLEGPGTPEVLGDEPRLRQVLSNLVGNALQHT-PD
MSMEG_5304|M.smegmatis_MC2_155      AQADERGIALTVTEDTQL---SDETVLSGPELVTVLGNLIDNAMDACDRD
Mvan_4697|M.vanbaalenii_PYR-1       AQADERGIELTVTEESALPADTDDLLLTGQEMVTVAGNLIDNAMDACDPQ
MAV_3405|M.avium_104                AEAEAARVRRDADCAVHTDIRPARLLADPAAMTRMIRNLVDNAVRHA---
Mflv_3003|M.gilvum_PYR-GCK          SLAAESGVALDLDPASHLAALDPALATD---VITLLGNLIDNAVDVSVGS
MLBr_00774|M.leprae_Br4923          GNVGHLAEEAGIELLVDMPVDEVIAEVDARRVERILRNLIANAIDHS--E
TH_2452|M.thermoresistible__bu      DKVVQLGDRD----YQLQSVAEVTAVLDAQRITQALIALADNACRYT-RD
MAB_3251c|M.abscessus_ATCC_199      AQRALLGATENDRKRVHLDLGGAVVRADPGLLERVLANLVDNALRYS---
                                                                   :      *  **       

Mb0781|M.bovis_AF2122/97            SADVTVRVGTEGDDAILEVADDGPGMSQEDALRVFERFYRADSSRARASG
Rv0758|M.tuberculosis_H37Rv         SADVTVRVGTEGDDAILEVADDGPGMSQEDALRVFERFYRADSSRARASG
MMAR_4941|M.marinum_M               SADVTVRVGTAGQNAVLEVADKGPGMPAEDAARVFERFYRTDSSRARASG
MUL_0464|M.ulcerans_Agy99           SADVTVRVGTAGENAVLEVADKGPGMPAEDAARVFERFYRTDSSRARASG
MSMEG_5304|M.smegmatis_MC2_155      DPWIEVTVTSDDDQLLITVADSGPGMDPDTFEKATQRGYSTK----ADTS
Mvan_4697|M.vanbaalenii_PYR-1       DPWVEVTVNQNSERLLIRVADSGEGMDAGTFEKAMRRGYSTKS--GAEAD
MAV_3405|M.avium_104                VSCVAIEVGSRDGTAVLTVGDDGPGIPPAQRSRVFERFVRLDTDRARSGG
Mflv_3003|M.gilvum_PYR-GCK          TPARVTVGIDDRDGLSILVSDTGPGVPEHLREAIFSRGVTSKP---DVPG
MLBr_00774|M.leprae_Br4923          HKPVRIRMAADEDTVAVTVRDYGIGLRPGEEKLVFSRFWRSDPSRVRRSG
TH_2452|M.thermoresistible__bu      GDWIAVGSGLYDGWLRFWVSDSGPGVSDADRDRIFERFARGSAG-GQRSD
MAB_3251c|M.abscessus_ATCC_199      QGEVRVSHEEVDDRTLVIVADHGKGLEASKRGAAFDAFQRLGDR--DNTV
                                                    . * * * *:                        

Mb0781|M.bovis_AF2122/97            GTGLGLSIVDSLVAAHGGAVTVTTALGEGCCFRVSLPRVSDVDQLSLTPV
Rv0758|M.tuberculosis_H37Rv         GTGLGLSIVDSLVAAHGGAVTVTTALGEGCCFRVSLPRVSDVDQLSLTPV
MMAR_4941|M.marinum_M               GTGLGLSIVHSLVKAHGGDVTLTTAPGEGCCFRVTLPRVSEAAVELTEPV
MUL_0464|M.ulcerans_Agy99           GTGLGLSIVHSLVKAHGGDVTLTTAPGEGCCFRVTLPRVSEAAVELTEPV
MSMEG_5304|M.smegmatis_MC2_155      GHGLGLALVAQVVNKHGGTLHADVTYGSVVTVTVPIPERVGGGHA-----
Mvan_4697|M.vanbaalenii_PYR-1       QHGLGLALVAQVVKRHHGQLSADVTYGSVVTVTVARP-------------
MAV_3405|M.avium_104                GAGLGLAIVAEVVAAHGGTVTIGDRPGGGTTLTVALPQHPAQHSSR----
Mflv_3003|M.gilvum_PYR-GCK          GRGIGLALVRLVTAQHGGTVEVADVPGGGARFEVRLKAATHA--------
MLBr_00774|M.leprae_Br4923          GTGLGLAISIEDARLHQGRLEAWGEPGQGACFRLTLPLVRGHKVTTSPLP
TH_2452|M.thermoresistible__bu      GAGLGLSIVRAIAGAHGGHVDLDTVVGRGSTFTITIPAVLEAPWPAS---
MAB_3251c|M.abscessus_ATCC_199      GVGLGLSVVKGFVEAMEGTVNATDTAGGGLTMIVDLPSAGSAPTGAIR--
                                      *:**::    .    * :      *    . :                

Mb0781|M.bovis_AF2122/97            VPGPP----------------------------
Rv0758|M.tuberculosis_H37Rv         VPGPP----------------------------
MMAR_4941|M.marinum_M               S--------------------------------
MUL_0464|M.ulcerans_Agy99           S--------------------------------
MSMEG_5304|M.smegmatis_MC2_155      ---------------------------------
Mvan_4697|M.vanbaalenii_PYR-1       ---------------------------------
MAV_3405|M.avium_104                ---------------------------------
Mflv_3003|M.gilvum_PYR-GCK          ---------------------------------
MLBr_00774|M.leprae_Br4923          MKPILQPSPQASTAGQQHGTQRQRLREHAERSR
TH_2452|M.thermoresistible__bu      ---------------------------------
MAB_3251c|M.abscessus_ATCC_199      ---------------------------------